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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Jul 1999 Volume 15 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
Jul 1999 Volume 15 Issue 1

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Article

Decreased expression of galectin-3 in basal cell carcinoma of the skin.

  • Authors:
    • V Castronovo
    • F T Liu
    • F A van den Brule
  • View Affiliations / Copyright

    Affiliations: Metastasis Research Laboratory, University Hospital, University of Liege, B-4000 Liege 1, Belgium.
  • Pages: 67-137
    |
    Published online on: July 1, 1999
       https://doi.org/10.3892/ijo.15.1.67
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Abstract

Galectins are beta-galactoside-binding lectins that play multiple roles during tumor progression. Previous work conducted in our laboratory has demonstrated decreased galectin-3 expression in carcinomas from colon, breast, ovary and endometrium, compared to the corresponding normal tissues. In this study, we examined the pattern of galectin-3 expression by immunohistochemistry in a group of 10 basal cell carcinomas of the skin. In the surrounding normal skin, galectin-3 immunostaining was found predominantly in the middle epidermis (spine layer) and eccrine sweat glands. Compared to the normal epidermal cells, basal carcinoma cells observed in all 10 samples examined presented with significantly decreased galectin-3 immunostaining. These data further demonstrates that galectin-3 is down-regulated in a variety of human cancers, including basal cell carcinoma.

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Copy and paste a formatted citation
Spandidos Publications style
Castronovo V, Liu F and van den Brule F: Decreased expression of galectin-3 in basal cell carcinoma of the skin.. Int J Oncol 15: 67-137, 1999.
APA
Castronovo, V., Liu, F., & van den Brule, F. (1999). Decreased expression of galectin-3 in basal cell carcinoma of the skin.. International Journal of Oncology, 15, 67-137. https://doi.org/10.3892/ijo.15.1.67
MLA
Castronovo, V., Liu, F., van den Brule, F."Decreased expression of galectin-3 in basal cell carcinoma of the skin.". International Journal of Oncology 15.1 (1999): 67-137.
Chicago
Castronovo, V., Liu, F., van den Brule, F."Decreased expression of galectin-3 in basal cell carcinoma of the skin.". International Journal of Oncology 15, no. 1 (1999): 67-137. https://doi.org/10.3892/ijo.15.1.67
Copy and paste a formatted citation
x
Spandidos Publications style
Castronovo V, Liu F and van den Brule F: Decreased expression of galectin-3 in basal cell carcinoma of the skin.. Int J Oncol 15: 67-137, 1999.
APA
Castronovo, V., Liu, F., & van den Brule, F. (1999). Decreased expression of galectin-3 in basal cell carcinoma of the skin.. International Journal of Oncology, 15, 67-137. https://doi.org/10.3892/ijo.15.1.67
MLA
Castronovo, V., Liu, F., van den Brule, F."Decreased expression of galectin-3 in basal cell carcinoma of the skin.". International Journal of Oncology 15.1 (1999): 67-137.
Chicago
Castronovo, V., Liu, F., van den Brule, F."Decreased expression of galectin-3 in basal cell carcinoma of the skin.". International Journal of Oncology 15, no. 1 (1999): 67-137. https://doi.org/10.3892/ijo.15.1.67
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