Prognostic significance of hTERT expression in non-small cell lung cancer.

  • Authors:
    • T Komiya
    • I Kawase
    • T Nitta
    • T Yasumitsu
    • M Kikui
    • M Fukuoka
    • K Nakagawa
    • T Hirashima
  • View Affiliations

  • Published online on: June 1, 2000     https://doi.org/10.3892/ijo.16.6.1173
  • Pages: 1173-1180
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Abstract

To investigate the prognostic role of hTERT expression in non-small cell lung cancer (NSCLC), we examined the expression of hTERT mRNA in tumor specimens from 68 patients with NSCLC using RT-PCR. The expression of hTERT was detected in 34 (50%) of 68 cancer tissues. There were no correlations between hTERT status and any common clinical features except age. Patients with hTERT expression had shorter survival than those without hTERT expression. Multivariate analysis showed that hTERT expression was an independent negative prognostic factor. These results suggest that expression of hTERT may be an independent prognostic factor for NSCLC patients.

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Jun 2000
Volume 16 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Komiya T, Kawase I, Nitta T, Yasumitsu T, Kikui M, Fukuoka M, Nakagawa K and Hirashima T: Prognostic significance of hTERT expression in non-small cell lung cancer.. Int J Oncol 16: 1173-1180, 2000
APA
Komiya, T., Kawase, I., Nitta, T., Yasumitsu, T., Kikui, M., Fukuoka, M. ... Hirashima, T. (2000). Prognostic significance of hTERT expression in non-small cell lung cancer.. International Journal of Oncology, 16, 1173-1180. https://doi.org/10.3892/ijo.16.6.1173
MLA
Komiya, T., Kawase, I., Nitta, T., Yasumitsu, T., Kikui, M., Fukuoka, M., Nakagawa, K., Hirashima, T."Prognostic significance of hTERT expression in non-small cell lung cancer.". International Journal of Oncology 16.6 (2000): 1173-1180.
Chicago
Komiya, T., Kawase, I., Nitta, T., Yasumitsu, T., Kikui, M., Fukuoka, M., Nakagawa, K., Hirashima, T."Prognostic significance of hTERT expression in non-small cell lung cancer.". International Journal of Oncology 16, no. 6 (2000): 1173-1180. https://doi.org/10.3892/ijo.16.6.1173