Treatment of hepatocellular carcinoma and the exacerbation of liver function

Okano,Hiroshi; Shiraki,Katsuya; Inoue,Hidekazu; Deguchi,Masatoshi; Sugimoto,Kazushi; Sakai,Takahisa; Ohmori,Shigeru; Murata,Kazumoto; Nakano,Takeshi; Yamakado,Koichiro; Takeda,Kan

doi:10.3892/ijo.19.6.1279

December 2001 Volume 19 Issue 6

Full Size Image

Cover Legend PDF

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

December 2001 Volume 19 Issue 6

Full Size Image

Cover Legend PDF

Article

Treatment of hepatocellular carcinoma and the exacerbation of liver function

Authors:
- Hiroshi Okano
- Katsuya Shiraki
- Hidekazu Inoue
- Masatoshi Deguchi
- Kazushi Sugimoto
- Takahisa Sakai
- Shigeru Ohmori
- Kazumoto Murata
- Takeshi Nakano
- Koichiro Yamakado
- Kan Takeda
View Affiliations / Copyright

Affiliations: First Department of Internal Medicine, Mie University School of Medicine, Tsu 514-8507, Japan
Pages: 1279-1282
|
Published online on: December 1, 2001

https://doi.org/10.3892/ijo.19.6.1279
Expand metrics +

Abstract

We performed interventional treatments on 50 patients with hepatocellular carcinoma (HCC) and analyzed the relationship between these treatments and the exacerbation of liver function after treatment. The different treatments included transcatheter arterial embolization (TAE), percutaneous ethanol injection therapy (PEIT), selective segmental sclerotherapy (SSS), combined TAE and PEIT, or transcatheter arterial chemo-injection (TAI). Thirteen patients showed an exacerbation of liver function after treatment. The laboratory data on admission, showed the lower levels of serum albumin and cholinesterase in this group. In comparison to patients who did not show any exacerbation of liver function, these 13 patients had undergone combined TAE and PEIT. An analysis of cases after TAE and PEIT treatment revealed that the time from TAE to PEIT was shorter in the exacerbation group than in the non-exacerbation group, however, there was no significant difference in the amount of injected ethanol between the two groups. It is assumed that the values of albumin and cholinesterase before treatment, or the period from TAE to PEIT are related to liver failure after treatment. Combining TAE and PEIT treatment may be effective for HCC, however, we should pay special attention to liver failure after treatment.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Treatment of hepatocellular carcinoma and the exacerbation of liver function

This article is mentioned in:

Abstract

Related Articles