IMPACT OF DELAY TO TREATMENT UPON SURVIVAL IN 1067 PATIENTS WITH BREAST-CANCER

RABINOVICH,MG; VALLEJO,CT; PEREZ,JE; RODRIGUEZ,R; CUEVAS,MA; MACHIAVELLI,MR; LACAVA,JA; LEONE,BA; ROMERO,AO; MICKIEWICZ,E; CHACON,RD; ESTEVEZ,RA

doi:10.3892/ijo.2.2.197

February 1993 Volume 2 Issue 2

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February 1993 Volume 2 Issue 2

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Article

IMPACT OF DELAY TO TREATMENT UPON SURVIVAL IN 1067 PATIENTS WITH BREAST-CANCER

Authors:
- MG RABINOVICH
- CT VALLEJO
- JE PEREZ
- R RODRIGUEZ
- MA CUEVAS
- MR MACHIAVELLI
- JA LACAVA
- BA LEONE
- AO ROMERO
- E MICKIEWICZ
- RD CHACON
- RA ESTEVEZ
View Affiliations / Copyright

Affiliations: INST ANGEL H ROFFO,RA-1417 BUENOS AIRES,ARGENTINA. CLIN INDEPENDENCIA,RA-1605 MUNRO,BUENOS AIRES,ARGENTINA. UNIV SALVADOR,CATEDRA ONCOL,RA-1425 BUENOS AIRES,ARGENTINA.
Pages: 197-201
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Published online on: February 1, 1993

https://doi.org/10.3892/ijo.2.2.197
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Abstract

The medical records of 1067 patients with breast cancer were reviewed to evaluate the influence of delay between first symptom and first treatment upon survival. Three delay intervals were considered: <3 months; 3-6 months and >6 months. At a follow-up of 120 months, survival analyses identified a statistically significant difference (p=0.029) favoring patients with <3 months delay in the whole cohort, and in the group of women aged 50 or older (p=0.001). No differences were found when survival according to delay was considered within each clinical stage. A Cox multivariate analysis revealed that performance status, stage, age and menopausal status were significant predictors of survival for the whole group of patients. However, delay was an independent prognostic factor in patients with age greater-than-or-equal-to 50. In summary, 38/1067 patients (3.1%) could have been adversely affected by a >3 months delay between first symptom and first treatment. Better survival rate for patients with a short delay would obey to a greater number of patients in favorable stages and a higher proportion of women aged 50 or older in this group.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

IMPACT OF DELAY TO TREATMENT UPON SURVIVAL IN 1067 PATIENTS WITH BREAST-CANCER

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