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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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April 1993 Volume 2 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April 1993 Volume 2 Issue 4

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Article

PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER

  • Authors:
    • Y YONEMURA
    • M KAJI
    • H TAKAMURA
    • K SUGIYAMA
    • I NINOMIYA
    • K TSUGAWA
    • T FUJIMURA
    • H FUJITA
    • A YAMAGUCHI
    • G NISHIMURA
    • I MIYAZAKI
  • View Affiliations / Copyright

    Affiliations: Affliations not specified
  • Pages: 577-582
    |
    Published online on: April 1, 1993
       https://doi.org/10.3892/ijo.2.4.577
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Abstract

The prognostic value of nucleolar organizer region (Ag-NOR) and ploidy status in 233 gastric cancer was determined. In addition, correlation of bromodeoxyuridine labeling indices (BrdU LIs) and Ag-NOR scores was studied. The proportion of Ag-NOR scores varied from 1.85 to 12.0 (mean, 3.6; S.D., 1.9). A significant correlation was found between Ag-NOR scores and BrdU LIs, tumor size, serosal invasion, and lymph node metastasis. By univariate analysis, Ag-NOR score was proved to be a significant prognostic indicator. However, Cox regression analysis revealed that Ag-NOR scores and DNA ploidy were not independent prognostic parameters. However, when the combination analysis of Ag-NOR scores and DNA ploidy was entered into the Cox model, this parameter emerged as an independent prognostic parameter. These studies indicate that Ag-NOR scores reflect proliferative activity of gastric cancer, and that the Ag-NOR scores may possibly be useful prognostic parameters, when combined with DNA ploidy.

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Copy and paste a formatted citation
Spandidos Publications style
YONEMURA Y, KAJI M, TAKAMURA H, SUGIYAMA K, NINOMIYA I, TSUGAWA K, FUJIMURA T, FUJITA H, YAMAGUCHI A, NISHIMURA G, NISHIMURA G, et al: PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER. Int J Oncol 2: 577-582, 1993.
APA
YONEMURA, Y., KAJI, M., TAKAMURA, H., SUGIYAMA, K., NINOMIYA, I., TSUGAWA, K. ... MIYAZAKI, I. (1993). PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER. International Journal of Oncology, 2, 577-582. https://doi.org/10.3892/ijo.2.4.577
MLA
YONEMURA, Y., KAJI, M., TAKAMURA, H., SUGIYAMA, K., NINOMIYA, I., TSUGAWA, K., FUJIMURA, T., FUJITA, H., YAMAGUCHI, A., NISHIMURA, G., MIYAZAKI, I."PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER". International Journal of Oncology 2.4 (1993): 577-582.
Chicago
YONEMURA, Y., KAJI, M., TAKAMURA, H., SUGIYAMA, K., NINOMIYA, I., TSUGAWA, K., FUJIMURA, T., FUJITA, H., YAMAGUCHI, A., NISHIMURA, G., MIYAZAKI, I."PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER". International Journal of Oncology 2, no. 4 (1993): 577-582. https://doi.org/10.3892/ijo.2.4.577
Copy and paste a formatted citation
x
Spandidos Publications style
YONEMURA Y, KAJI M, TAKAMURA H, SUGIYAMA K, NINOMIYA I, TSUGAWA K, FUJIMURA T, FUJITA H, YAMAGUCHI A, NISHIMURA G, NISHIMURA G, et al: PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER. Int J Oncol 2: 577-582, 1993.
APA
YONEMURA, Y., KAJI, M., TAKAMURA, H., SUGIYAMA, K., NINOMIYA, I., TSUGAWA, K. ... MIYAZAKI, I. (1993). PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER. International Journal of Oncology, 2, 577-582. https://doi.org/10.3892/ijo.2.4.577
MLA
YONEMURA, Y., KAJI, M., TAKAMURA, H., SUGIYAMA, K., NINOMIYA, I., TSUGAWA, K., FUJIMURA, T., FUJITA, H., YAMAGUCHI, A., NISHIMURA, G., MIYAZAKI, I."PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER". International Journal of Oncology 2.4 (1993): 577-582.
Chicago
YONEMURA, Y., KAJI, M., TAKAMURA, H., SUGIYAMA, K., NINOMIYA, I., TSUGAWA, K., FUJIMURA, T., FUJITA, H., YAMAGUCHI, A., NISHIMURA, G., MIYAZAKI, I."PROGNOSTIC VALUE OF NUCLEOLAR ORGANIZER REGIONS AND DNA PLOIDY IN GASTRIC-CANCER". International Journal of Oncology 2, no. 4 (1993): 577-582. https://doi.org/10.3892/ijo.2.4.577
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