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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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May 1993 Volume 2 Issue 5

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
May 1993 Volume 2 Issue 5

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Article

INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA

  • Authors:
    • A CIVIDALLI
    • FP GENTILE
    • L BEGNOZZI
    • L CHIATTI
    • M BENASSI
    • A FLORIDI
  • View Affiliations / Copyright

    Affiliations: REGINA ELENA INST CANC RES,CTR EXPTL RES,CELL METAB & PHARMACOKINET LAB,VIA MESSI ORO 156,I-00158 ROME,ITALY. ENEA,DEPT BIOL & HEALTHY EFFECTS,I-00060 ROME,ITALY. REGINA ELENA INST CANC RES,CTR EXPTL RES,MED PHYS & EXPERT SYST LAB,I-00158 ROME,ITALY.
  • Pages: 791-795
    |
    Published online on: May 1, 1993
       https://doi.org/10.3892/ijo.2.5.791
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Abstract

The effect of lonidamine (LND) in association with fractionated doses of radiation and/or hyperthermia on tumor growth has been evaluated. The results may be summarized as follows: (i) the fractionation of the radiation dose, in spite of the higher dose delivered (20 Gy) does not increase tumor growth delay when compared to that obtained with a single irradiation treatment. A similar behaviour was also found when the fractionated irradiation was associated with LND. (ii) Hyperthermia is less effective than radiation in controlling tumor growth, but its effect is potentiated by LND although to a lesser extent that with radiation. (iii) LND delivered together with hyperthermia and radiation arrests tumor growth, and leads to the disappearance of the tumor in 75% of mice. The possible mechanisms underlying these effects are discussed.

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Copy and paste a formatted citation
Spandidos Publications style
CIVIDALLI A, GENTILE F, BEGNOZZI L, CHIATTI L, BENASSI M and FLORIDI A: INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA. Int J Oncol 2: 791-795, 1993.
APA
CIVIDALLI, A., GENTILE, F., BEGNOZZI, L., CHIATTI, L., BENASSI, M., & FLORIDI, A. (1993). INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA. International Journal of Oncology, 2, 791-795. https://doi.org/10.3892/ijo.2.5.791
MLA
CIVIDALLI, A., GENTILE, F., BEGNOZZI, L., CHIATTI, L., BENASSI, M., FLORIDI, A."INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA". International Journal of Oncology 2.5 (1993): 791-795.
Chicago
CIVIDALLI, A., GENTILE, F., BEGNOZZI, L., CHIATTI, L., BENASSI, M., FLORIDI, A."INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA". International Journal of Oncology 2, no. 5 (1993): 791-795. https://doi.org/10.3892/ijo.2.5.791
Copy and paste a formatted citation
x
Spandidos Publications style
CIVIDALLI A, GENTILE F, BEGNOZZI L, CHIATTI L, BENASSI M and FLORIDI A: INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA. Int J Oncol 2: 791-795, 1993.
APA
CIVIDALLI, A., GENTILE, F., BEGNOZZI, L., CHIATTI, L., BENASSI, M., & FLORIDI, A. (1993). INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA. International Journal of Oncology, 2, 791-795. https://doi.org/10.3892/ijo.2.5.791
MLA
CIVIDALLI, A., GENTILE, F., BEGNOZZI, L., CHIATTI, L., BENASSI, M., FLORIDI, A."INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA". International Journal of Oncology 2.5 (1993): 791-795.
Chicago
CIVIDALLI, A., GENTILE, F., BEGNOZZI, L., CHIATTI, L., BENASSI, M., FLORIDI, A."INVIVO CONTROL OF TUMOR-GROWTH WITH THE ASSOCIATION OF IONIDAMINE WITH RADIATION AND OR HYPERTHERMIA". International Journal of Oncology 2, no. 5 (1993): 791-795. https://doi.org/10.3892/ijo.2.5.791
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