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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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May 2013 Volume 42 Issue 5

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

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Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

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Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

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Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

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Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

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International Journal of Epigenetics

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Article

Selenium-binding protein 1 may decrease gastric cellular proliferation and migration

Retraction in: /10.3892/ijo.2025.5731
  • Authors:
    • Chenjing Zhang
    • Wen Xu
    • Wensheng Pan
    • Nana Wang
    • Guogang Li
    • Xiaoyuan Fan
    • Xiang Xu
    • Shengrong Shen
    • Undurti N. Das
  • View Affiliations / Copyright

    Affiliations: Department of Gastroenterology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, P.R. China, Department of Internal Medicine, Tianhe Hospital, Tianjin 300070, P.R. China, Department of Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, P.R. China, Department of Gastroenterology, Yinzhou People's Hospital, Ningbo 315040, P.R. China, Department of Pharmacy, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, P.R. China, Zhejiang University School of Biosystems Engineering and Food Science, Hangzhou 310000, P.R. China, UND Life Sciences, Shaker Heights, OH 44120, USA
  • Pages: 1620-1629
    |
    Published online on: March 7, 2013
       https://doi.org/10.3892/ijo.2013.1850
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Abstract

It has been reported that suppression of selenium‑binding protein 1 (SBP1) occurs in many human malignancies which is considered to play an important role in cancer development and progression. Despite its importance in cancer, the function and factors that regulate its expression are not known. Using cell proliferation assays, immunochemical staining and immunoblotting and flow cytometry methods and in a xenograft model, we evaluated the role of SBP1 in proliferation, migration, senescence and chemoresistance of gastric cancer cells (SGC7901 and BGC823) to cisplatin. It was noted that diminished SBP1 expression increased gastric cancer cell proliferation and cell migration and decreased cisplatin-induced apoptosis while its overexpression produced the opposite effects. These results suggest that SBP1 plays a significant role in gastric cancer cell proliferation and modulates its response to anticancer drugs. These results suggest that SBP1 can serve as a potential target to suppress gastric cancer.
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Copy and paste a formatted citation
Spandidos Publications style
Zhang C, Xu W, Pan W, Wang N, Li G, Fan X, Xu X, Shen S and Das UN: Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731. Int J Oncol 42: 1620-1629, 2013.
APA
Zhang, C., Xu, W., Pan, W., Wang, N., Li, G., Fan, X. ... Das, U.N. (2013). Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731. International Journal of Oncology, 42, 1620-1629. https://doi.org/10.3892/ijo.2013.1850
MLA
Zhang, C., Xu, W., Pan, W., Wang, N., Li, G., Fan, X., Xu, X., Shen, S., Das, U. N."Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731". International Journal of Oncology 42.5 (2013): 1620-1629.
Chicago
Zhang, C., Xu, W., Pan, W., Wang, N., Li, G., Fan, X., Xu, X., Shen, S., Das, U. N."Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731". International Journal of Oncology 42, no. 5 (2013): 1620-1629. https://doi.org/10.3892/ijo.2013.1850
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang C, Xu W, Pan W, Wang N, Li G, Fan X, Xu X, Shen S and Das UN: Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731. Int J Oncol 42: 1620-1629, 2013.
APA
Zhang, C., Xu, W., Pan, W., Wang, N., Li, G., Fan, X. ... Das, U.N. (2013). Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731. International Journal of Oncology, 42, 1620-1629. https://doi.org/10.3892/ijo.2013.1850
MLA
Zhang, C., Xu, W., Pan, W., Wang, N., Li, G., Fan, X., Xu, X., Shen, S., Das, U. N."Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731". International Journal of Oncology 42.5 (2013): 1620-1629.
Chicago
Zhang, C., Xu, W., Pan, W., Wang, N., Li, G., Fan, X., Xu, X., Shen, S., Das, U. N."Selenium-binding protein 1 may decrease gastric cellular proliferation and migration Retraction in /10.3892/ijo.2025.5731". International Journal of Oncology 42, no. 5 (2013): 1620-1629. https://doi.org/10.3892/ijo.2013.1850
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