|
1
|
Medes G, Thomas A and Weinhouse S:
Metabolism of neoplastic tissue. IV A study of lipid synthesis in
neoplastic tissue slices in vitro. Cancer Res. 13:27–29.
1953.PubMed/NCBI
|
|
2
|
Swinnen JV, Brusselmans K and Verhoeven G:
Increased lipogenesis in cancer cells: new players, novel targets.
Curr Opin Clin Nutr Metab Care. 9:358–365. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Postic C and Girard J: The role of the
lipogenic pathway in the development of hepatic steatosis. Diabetes
Metab. 34:643–648. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ntambi JM: The regulation of stearoyl-CoA
desaturase (SCD). Prog Lipid Res. 34:139–150. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Neuschwander-Tetri BA: Hepatic
lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis:
the central role of nontriglyceride fatty acid metabolites.
Hepatology. 52:774–788. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Viollet B, Guigas B, Leclerc J, et al:
AMP-activated protein kinase in the regulation of hepatic energy
metabolism: from physiology to therapeutic perspectives. Acta
Physiol (Oxf). 196:81–98. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Viollet B, Foretz M, Guigas B, et al:
Activation of AMP-activated protein kinase in the liver: a new
strategy for the management of metabolic hepatic disorders. J
Physiol. 574:41–53. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kuhajda FP: Fatty-acid synthase and human
cancer: new perspectives on its role in tumor biology. Nutrition.
16:202–208. 2000. View Article : Google Scholar
|
|
9
|
Bougnoux P, Chajes V, Lanson M, et al:
Prognostic significance of tumor phosphatidylcholine stearic acid
level in breast carcinoma. Breast Cancer Res Treat. 20:185–194.
1992. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Guo D, Reinitz F, Youssef M, et al: An LXR
agonist promotes glioblastoma cell death through inhibition of an
EGFR/AKT/SREBP-1/LDLR-dependent pathway. Cancer Discov. 1:442–456.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Nieva C, Marro M, Santana-Codina N, Rao S,
Petrov D and Sierra A: The lipid phenotype of breast cancer cells
characterized by Raman microspectroscopy: towards a stratification
of malignancy. PLoS One. 7:e464562012. View Article : Google Scholar
|
|
12
|
Pizer ES, Chrest FJ, DiGiuseppe JA and Han
WF: Pharmacological inhibitors of mammalian fatty acid synthase
suppress DNA replication and induce apoptosis in tumor cell lines.
Cancer Res. 58:4611–4615. 1998.PubMed/NCBI
|
|
13
|
Horiguchi A, Asano T, Asano T, Ito K,
Sumitomo M and Hayakawa M: Pharmacological inhibitor of fatty acid
synthase suppresses growth and invasiveness of renal cancer cells.
J Urol. 180:729–736. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ma J, Yan R, Zu X, et al: Aldo-keto
reductase family 1 B10 affects fatty acid synthesis by regulating
the stability of acetyl-CoA carboxylase-alpha in breast cancer
cells. J Biol Chem. 283:3418–3423. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chajes V, Cambot M, Moreau K, Lenoir GM
and Joulin V: Acetyl-CoA carboxylase alpha is essential to breast
cancer cell survival. Cancer Res. 66:5287–5294. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Brusselmans K, De Schrijver E, Verhoeven G
and Swinnen JV: RNA interference-mediated silencing of the
acetyl-CoA-carboxylase-alpha gene induces growth inhibition and
apoptosis of prostate cancer cells. Cancer Res. 65:6719–6725. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhan Y, Ginanni N, Tota MR, et al: Control
of cell growth and survival by enzymes of the fatty acid synthesis
pathway in HCT-116 colon cancer cells. Clin Cancer Res.
14:5735–5742. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Scaglia N, Caviglia JM and Igal RA: High
stearoyl-CoA desaturase protein and activity levels in simian virus
40 transformed-human lung fibroblasts. Biochim Biophys Acta.
1687:141–151. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Scaglia N, Chisholm JW and Igal RA:
Inhibition of stearoylCoA desaturase-1 inactivates acetyl-CoA
carboxylase and impairs proliferation in cancer cells: role of
AMPK. PloS One. 4:e68122009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Scaglia N and Igal RA: Inhibition of
stearoyl-CoA desaturase 1 expression in human lung adenocarcinoma
cells impairs tumorigenesis. Int J Oncol. 33:839–850.
2008.PubMed/NCBI
|
|
21
|
Morgan-Lappe SE, Tucker LA, Huang X, et
al: Identification of Ras-related nuclear protein, targeting
protein for xenopus kinesin-like protein 2, and stearoyl-CoA
desaturase 1 as promising cancer targets from an RNAi-based screen.
Cancer Res. 67:4390–4398. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Guo D, Prins RM, Dang J, et al: EGFR
signaling through an Akt-SREBP-1-dependent, rapamycin-resistant
pathway sensitizes glioblastomas to antilipogenic therapy. Sci
Signal. 2:ra822009.PubMed/NCBI
|
|
23
|
Zhang D, Tai LK, Wong LL, Chiu LL, Sethi
SK and Koay ES: Proteomic study reveals that proteins involved in
metabolic and detoxification pathways are highly expressed in
HER-2/neu-positive breast cancer. Mol Cell Proteomics. 4:1686–1696.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Porstmann T, Griffiths B, Chung YL, et al:
PKB/Akt induces transcription of enzymes involved in cholesterol
and fatty acid biosynthesis via activation of SREBP. Oncogene.
24:6465–6481. 2005.PubMed/NCBI
|
|
25
|
Wang HQ, Altomare DA, Skele KL, et al:
Positive feedback regulation between AKT activation and fatty acid
synthase expression in ovarian carcinoma cells. Oncogene.
24:3574–3582. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bandyopadhyay S, Pai SK, Watabe M, et al:
FAS expression inversely correlates with PTEN level in prostate
cancer and a PI 3-kinase inhibitor synergizes with FAS siRNA to
induce apoptosis. Oncogene. 24:5389–5395. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Chang Y, Wang J, Lu X, Thewke DP and Mason
RJ: KGF induces lipogenic genes through a PI3K and JNK/SREBP-1
pathway in H292 cells. J Lipid Res. 46:2624–2635. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Swinnen JV, Beckers A, Brusselmans K, et
al: Mimicry of a cellular low energy status blocks tumor cell
anabolism and suppresses the malignant phenotype. Cancer Res.
65:2441–2448. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Mehes G, Witt A, Kubista E and Ambros PF:
Circulating breast cancer cells are frequently apoptotic. Am J
Pathol. 159:17–20. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Iwatsuki M, Mimori K, Yokobori T, et al:
Epithelial-mesenchymal transition in cancer development and its
clinical significance. Cancer Sci. 101:293–299. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Polyak K and Weinberg RA: Transitions
between epithelial and mesenchymal states: acquisition of malignant
and stem cell traits. Nat Rev Cancer. 9:265–273. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Thiery JP: Epithelial-mesenchymal
transitions in tumour progression. Nat Rev Cancer. 2:442–454. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Voulgari A and Pintzas A:
Epithelial-mesenchymal transition in cancer metastasis: mechanisms,
markers and strategies to overcome drug resistance in the clinic.
Biochim Biophys Acta. 1796:75–90. 2009.PubMed/NCBI
|
|
34
|
Yang J, Mani SA, Donaher JL, et al: Twist,
a master regulator of morphogenesis, plays an essential role in
tumor metastasis. Cell. 117:927–939. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Batlle E, Sancho E, Franci C, et al: The
transcription factor snail is a repressor of E-cadherin gene
expression in epithelial tumour cells. Nat Cell Biol. 2:84–89.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Darnell JE Jr: Transcription factors as
targets for cancer therapy. Nature reviews Cancer. 2:740–749. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Moustakas A and Heldin CH: Signaling
networks guiding epithelial-mesenchymal transitions during
embryogenesis and cancer progression. Cancer Sci. 98:1512–1520.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Blobe GC, Schiemann WP and Lodish HF: Role
of transforming growth factor beta in human disease. N Engl J Med.
342:1350–1358. 2000. View Article : Google Scholar
|
|
39
|
Stambolic V and Woodgett JR: Mitogen
inactivation of glycogen synthase kinase-3 beta in intact cells via
serine 9 phosphorylation. Biochem J. 303:701–704. 1994.
|
|
40
|
Peinado H, Portillo F and Cano A:
Transcriptional regulation of cadherins during development and
carcinogenesis. Int J Dev Biol. 48:365–375. 2004. View Article : Google Scholar
|
|
41
|
Hamada F and Bienz M: The APC tumor
suppressor binds to C-terminal binding protein to divert nuclear
beta-catenin from TCF. Dev Cell. 7:677–685. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
He TC, Sparks AB, Rago C, et al:
Identification of c-MYC as a target of the APC pathway. Science.
281:1509–1512. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Takeichi M, Nakagawa S, Aono S, Usui T and
Uemura T: Patterning of cell assemblies regulated by adhesion
receptors of the cadherin superfamily. Philos Trans R Soc Lond B
Biol Sci. 355:885–890. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Efstathiou JA and Pignatelli M: Modulation
of epithelial cell adhesion in gastrointestinal homeostasis. Am J
Pathol. 153:341–347. 1998. View Article : Google Scholar
|
|
45
|
Wijnhoven BP and Pignatelli M:
E-cadherin-catenin: more than a ‘sticky’ molecular complex. Lancet.
354:356–357. 1999.
|
|
46
|
Gilles C, Polette M, Mestdagt M, et al:
Transactivation of vimentin by beta-catenin in human breast cancer
cells. Cancer Res. 63:2658–2664. 2003.PubMed/NCBI
|
|
47
|
Takahashi M, Tsunoda T, Seiki M, Nakamura
Y and Furukawa Y: Identification of membrane-type matrix
metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in
human colorectal cancers. Oncogene. 21:5861–5867. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Rakha EA: Pitfalls in outcome prediction
of breast cancer. J Clin Pathol. 66:458–464. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Milgraum LZ, Witters LA, Pasternack GR and
Kuhajda FP: Enzymes of the fatty acid synthesis pathway are highly
expressed in in situ breast carcinoma. Clin Cancer Res.
3:2115–2120. 1997.PubMed/NCBI
|
|
50
|
Epstein JI, Carmichael M and Partin AW:
OA-519 (fatty acid synthase) as an independent predictor of
pathologic state in adenocarcinoma of the prostate. Urology.
45:81–86. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Lupu R and Menendez JA: Targeting fatty
acid synthase in breast and endometrial cancer: An alternative to
selective estrogen receptor modulators? Endocrinology.
147:4056–4066. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Davidson B, Smith Y, Nesland JM, Kaern J,
Reich R and Trope CG: Defining a prognostic marker panel for
patients with ovarian serous carcinoma effusion. Hum Pathol.
44:2449–2460. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Pflug BR, Pecher SM, Brink AW, Nelson JB
and Foster BA: Increased fatty acid synthase expression and
activity during progression of prostate cancer in the TRAMP model.
Prostate. 57:245–254. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Greenberg NM, DeMayo F, Finegold MJ, et
al: Prostate cancer in a transgenic mouse. Proc Natl Acad Sci USA.
92:3439–3443. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Migita T, Ruiz S, Fornari A, Fiorentino M,
Priolo C, Zadra G, et al: Fatty acid synthase: a metabolic enzyme
and candidate oncogene in prostate cancer. J Natl Cancer Inst.
101:519–532. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Swinnen JV, Esquenet M, Goossens K, Heyns
W and Verhoeven G: Androgens stimulate fatty acid synthase in the
human prostate cancer cell line LNCaP. Cancer Res. 57:1086–1090.
1997.PubMed/NCBI
|
|
57
|
Heemers H, Maes B, Foufelle F, Heyns W,
Verhoeven G and Swinnen JV: Androgens stimulate lipogenic gene
expression in prostate cancer cells by activation of the sterol
regulatory element-binding protein cleavage activating
protein/sterol regulatory element-binding protein pathway. Mol
Endocrinol. 15:1817–1828. 2001. View Article : Google Scholar
|
|
58
|
Van de Sande T, De Schrijver E, Heyns W,
Verhoeven G and Swinnen JV: Role of the phosphatidylinositol
3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty
acid synthase in LNCaP prostate cancer cells. Cancer Res.
62:642–646. 2002.
|
|
59
|
Graner E, Tang D, Rossi S, et al: The
isopeptidase USP2a regulates the stability of fatty acid synthase
in prostate cancer. Cancer Cell. 5:253–261. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Selvendiran K, Ahmed S, Dayton A, et al:
HO-3867, a synthetic compound, inhibits the migration and invasion
of ovarian carcinoma cells through downregulation of fatty acid
synthase and focal adhesion kinase. Mol Cancer Res. 8:1188–1197.
2010. View Article : Google Scholar
|
|
61
|
Hsu YC and Liou YM: The anti-cancer
effects of (−)-epigallocatechin-3-gallate on the signaling pathways
associated with membrane receptors in MCF-7 cells. J Cell Physiol.
226:2721–2730. 2011.
|
|
62
|
Menendez JA, Vellon L, Mehmi I, et al:
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu
(erbB-2) oncogene overexpression in cancer cells. Proc Natl Acad
Sci USA. 101:10715–10720. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Hartkopf AD, Banys M and Fehm T:
HER2-positive DTCs/CTCs in breast cancer. Recent Results Cancer
Res. 195:203–215. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Lee JS, Yoon IS, Lee MS, et al: Anticancer
activity of pristimerin in epidermal growth factor receptor
2-positive SKBR3 human breast cancer cells. Biol Pharm Bull.
36:316–325. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Swinnen JV, Heemers H, Deboel L, Foufelle
F, Heyns W and Verhoeven G: Stimulation of tumor-associated fatty
acid synthase expression by growth factor activation of the sterol
regulatory element-binding protein pathway. Oncogene. 19:5173–5181.
2000. View Article : Google Scholar
|
|
66
|
Oskouian B: Overexpression of fatty acid
synthase in SKBR3 breast cancer cell line is mediated via a
transcriptional mechanism. Cancer Lett. 149:43–51. 2000. View Article : Google Scholar
|
|
67
|
Kumar-Sinha C, Ignatoski KW, Lippman ME,
Ethier SP and Chinnaiyan AM: Transcriptome analysis of HER2 reveals
a molecular connection to fatty acid synthesis. Cancer Res.
63:132–139. 2003.PubMed/NCBI
|
|
68
|
Nicolini A, Giardino R, Carpi A, et al:
Metastatic breast cancer: an updating. Biomed Pharmacother.
60:548–556. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Camassei FD, Cozza R, Acquaviva A, et al:
Expression of the lipogenic enzyme fatty acid synthase (FAS) in
retinoblastoma and its correlation with tumor aggressiveness.
Invest Ophthalmol Vis Sci. 44:2399–2403. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Rashid A, Pizer ES, Moga M, et al:
Elevated expression of fatty acid synthase and fatty acid synthetic
activity in colorectal neoplasia. Am J Pathol. 150:201–208.
1997.PubMed/NCBI
|
|
71
|
Kalyankrishna S and Grandis JR: Epidermal
growth factor receptor biology in head and neck cancer. J Clin
Oncol. 24:2666–2672. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Qiu Z, Huang C, Sun J, et al: RNA
interference-mediated signal transducers and activators of
transcription 3 gene silencing inhibits invasion and metastasis of
human pancreatic cancer cells. Cancer Sci. 98:1099–1106. 2007.
View Article : Google Scholar
|
|
73
|
Horiguchi A, Asano T, Asano T, Ito K,
Sumitomo M and Hayakawa M: Fatty acid synthase over expression is
an indicator of tumor aggressiveness and poor prognosis in renal
cell carcinoma. J Urol. 180:1137–1140. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Piyathilake CJ, Frost AR, Manne U, Bell
WC, Weiss H, Heimburger DC, et al: The expression of fatty acid
synthase (FASE) is an early event in the development and
progression of squamous cell carcinoma of the lung. Hum Pathol.
31:1068–1073. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Carvalho MA, Zecchin KG, Seguin F, et al:
Fatty acid synthase inhibition with Orlistat promotes apoptosis and
reduces cell growth and lymph node metastasis in a mouse melanoma
model. Int J Cancer. 123:2557–2565. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Murata S, Yanagisawa K, Fukunaga K, et al:
Fatty acid synthase inhibitor cerulenin suppresses liver metastasis
of colon cancer in mice. Cancer Sci. 101:1861–1865. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Zaytseva YY, Rychahou PG, Gulhati P, et
al: Inhibition of fatty acid synthase attenuates CD44-associated
signaling and reduces metastasis in colorectal cancer. Cancer Res.
72:1504–1517. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Chajes V, Hulten K, Van Kappel AL, et al:
Fatty-acid composition in serum phospholipids and risk of breast
cancer: an incident case-control study in Sweden. Int J Cancer.
83:585–590. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Chajes V, Thiebaut AC, Rotival M, et al:
Association between serum trans-monounsaturated fatty acids and
breast cancer risk in the E3N-EPIC study. Am J Epidemiol.
167:1312–1320. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Pala V, Krogh V, Muti P, et al:
Erythrocyte membrane fatty acids and subsequent breast cancer: a
prospective Italian study. J Natl Cancer Inst. 93:1088–1095. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Mauvoisin D, Charfi C, Lounis AM, Rassart
E and Mounier C: Decreasing stearoyl-CoA desaturase-1 expression
inhibits beta-catenin signaling in breast cancer cells. Cancer Sci.
104:36–42. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Goodridge AG: Regulation of the activity
of acetyl coenzyme A carboxylase by palmitoyl coenzyme A and
citrate. J Biol Chem. 247:6946–6952. 1972.PubMed/NCBI
|
|
83
|
Zureik M, Ducimetiere P, Warnet JM and
Orssaud G: Fatty acid proportions in cholesterol esters and risk of
premature death from cancer in middle aged French men. BMJ.
311:1251–1254. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Petrek JA, Hudgins LC, Ho M, Bajorunas DR
and Hirsch J: Fatty acid composition of adipose tissue, an
indication of dietary fatty acids, and breast cancer prognosis. J
Clin Oncol. 15:1377–1384. 1997.PubMed/NCBI
|
|
85
|
Zhu ZR, Agren J, Mannisto S, et al: Fatty
acid composition of breast adipose tissue in breast cancer patients
and in patients with benign breast disease. Nutr Cancer.
24:151–160. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Simonsen NR, Fernandez-Crehuet Navajas J,
Martin-Moreno JM, et al: Tissue stores of individual
monounsaturated fatty acids and breast cancer: the EURAMIC study.
European Community Multicenter Study on Antioxidants, Myocardial
Infarction, and Breast. Cancer Am J Clin Nutr. 68:134–141.
1998.PubMed/NCBI
|
|
87
|
Lamouille S and Derynck R: Emergence of
the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin
axis in transforming growth factor-beta-induced
epithelial-mesenchymal transition. Cells Tissues Organs. 193:8–22.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Lin SY, Xia W, Wang JC, et al:
Beta-catenin, a novel prognostic marker for breast cancer: its
roles in cyclin D1 expression and cancer progression. Proc Natl
Acad Sci USA. 97:4262–4266. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Rios-Esteves J and Resh MD: Stearoyl CoA
desaturase is required to produce active, lipid-modified Wnt
proteins. Cell Rep. 4:1072–1081. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
90
|
Samuel W, Nagineni CN, Kutty RK, et al:
Transforming growth factor-beta regulates stearoyl coenzyme A
desaturase expression through a Smad signaling pathway. J Biol
Chem. 277:59–66. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
McIntyre E, Blackburn E, Brown PJ, Johnson
CG and Gullick WJ: The complete family of epidermal growth factor
receptors and their ligands are co-ordinately expressed in breast
cancer. Breast Cancer Res Treat. 122:105–110. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Menendez JA, Vazquez-Martin A, Ropero S,
Colomer R and Lupu R: HER2 (erbB-2)-targeted effects of the omega-3
polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in
breast cancer cells: the ‘fat features’ of the ‘Mediterranean diet’
as an ‘anti-HER2 cocktail’. Clin Transl Oncol. 8:812–820.
2006.PubMed/NCBI
|
|
93
|
Wells WA, Schwartz GN, Morganelli PM, Cole
BF, Gibson JJ and Kinlaw WB: Expression of ‘Spot 14’ (THRSP)
predicts disease free survival in invasive breast cancer:
immunohistochemical analysis of a new molecular marker. Breast
Cancer Res Treat. 98:231–240. 2006.
|
|
94
|
Kinlaw WB, Quinn JL, Wells WA, Roser-Jones
C and Moncur JT: Spot 14: A marker of aggressive breast cancer and
a potential therapeutic target. Endocrinology. 147:4048–4055. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Chin K, DeVries S, Fridlyand J, et al:
Genomic and transcriptional aberrations linked to breast cancer
pathophysiologies. Cancer Cell. 10:529–541. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
96
|
Moreau K, Dizin E, Ray H, et al: BRCA1
affects lipid synthesis through its interaction with acetyl-CoA
carboxylase. J Biol Chem. 281:3172–3181. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Saxena NK and Sharma D: Metastasis
suppression by adiponectin: LKB1 rises up to the challenge. Cell
Adh Migr. 4:358–362. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Scott KE, Wheeler FB, Davis AL, Thomas MJ,
Ntambi JM, Seals DF, et al: Metabolic regulation of invadopodia and
invasion by acetyl-CoA carboxylase 1 and de novo lipogenesis. PloS
One. 7:e297612012. View Article : Google Scholar : PubMed/NCBI
|
|
99
|
Menendez JA and Lupu R: Mediterranean
dietary traditions for the molecular treatment of human cancer:
anti-oncogenic actions of the main olive oil’s monounsaturated
fatty acid oleic acid (18:1n-9). Curr Pharm Biotechnol. 7:495–502.
2006.PubMed/NCBI
|
|
100
|
Swinnen JV, Ulrix W, Heyns W and Verhoeven
G: Coordinate regulation of lipogenic gene expression by androgens:
evidence for a cascade mechanism involving sterol regulatory
element binding proteins. Proc Natl Acad Sci USA. 94:12975–12980.
1997. View Article : Google Scholar
|
|
101
|
Huang WC, Li X, Liu J, Lin J and Chung LW:
Activation of androgen receptor, lipogenesis, and oxidative stress
converged by SREBP-1 is responsible for regulating growth and
progression of prostate cancer cells. Mol Cancer Res. 10:133–142.
2012. View Article : Google Scholar
|
|
102
|
Bhandary B, Marahatta A, Kim HR and Chae
HJ: Mitochondria in relation to cancer metastasis. J Bioenerg
Biomembr. 44:623–627. 2012. View Article : Google Scholar : PubMed/NCBI
|
