|
1
|
Nelson WJ: Adaptation of core mechanisms
to generate cell polarity. Nature. 422:766–774. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Tepass U, Theres C and Knust E: Crumbs
encodes an EGF-like protein expressed on apical membranes of
Drosophila epithelial cells and required for organization of
epithelia. Cell. 61:787–799. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Tepass U and Knust E: Crumbs and stardust
act in a genetic pathway that controls the organization of
epithelia in Drosophila melanogaster. Dev Biol. 159:311–326. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bhat MA, Izaddoost S, Lu Y, Cho KO, Choi
KW and Bellen HJ: Discs Lost, a novel multi-PDZ domain protein,
establishes and maintains epithelial polarity. Cell. 96:833–845.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Margolis B and Borg JP: Apicobasal
polarity complexes. J Cell Sci. 118:5157–5159. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Suzuki A and Ohno S: The PAR-aPKC system:
lessons in polarity. J Cell Sci. 119:979–987. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Bilder D: Epithelial polarity and
proliferation control: links from the Drosophila neoplastic tumor
suppressors. Genes Dev. 18:1909–1925. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Assémat E, Bazellières E,
Pallesi-Pocachard E, Le Bivic A and Massey-Harroche D: Polarity
complex proteins. Biochim Biophys Acta. 1778:614–630. 2008.
View Article : Google Scholar
|
|
9
|
Nolan ME, Aranda V, Lee S, et al: The
polarity protein Par6 induces cell proliferation and is
overexpressed in breast cancer. Cancer Res. 68:8201–8209. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Eder AM, Sui X, Rosen DG, et al: Atypical
PKCiota contributes to poor prognosis through loss of apical-basal
polarity and cyclin E overexpression in ovarian cancer. Proc Natl
Acad Sci USA. 102:12519–12524. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Regala RP, Weems C, Jamieson L, et al:
Atypical protein kinase C iota is an oncogene in human non-small
cell lung cancer. Cancer Res. 65:8905–8911. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Xue B, Krishnamurthy K, Allred DC and
Muthuswamy SK: Loss of Par3 promotes breast cancer metastasis by
compromising cell-cell cohesion. Nat Cell Biol. 15:189–200. 2013.
View Article : Google Scholar
|
|
13
|
McCaffrey LM, Montalbano J, Mihai C and
Macara IG: Loss of the Par3 polarity protein promotes breast
tumorigenesis and metastasis. Cancer cell. 22:601–614. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ellenbroek SI, Iden S and Collard JG: Cell
polarity proteins and cancer. Semin Cancer Biol. 22:208–215. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Spaderna S, Schmalhofer O, Wahlbuhl M, et
al: The transcriptional repressor ZEB1 promotes metastasis and loss
of cell polarity in cancer. Cancer Res. 68:537–544. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Sandoval GJ, Graham DB, Gmyrek GB, et al:
Novel mechanism of tumor suppression by polarity gene discs large 1
(DLG1) revealed in a murine model of pediatric B-ALL. Cancer
Immunol Res. 1:426–437. 2013. View Article : Google Scholar
|
|
17
|
Etienne-Manneville S: Polarity proteins in
migration and invasion. Oncogene. 27:6970–6980. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Dow LE and Humbert PO: Polarity regulators
and the control of epithelial architecture, cell migration, and
tumorigenesis. Int Rev Cytol. 262:253–302. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Martin-Belmonte F and Perez-Moreno M:
Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer.
12:23–38. 2011.PubMed/NCBI
|
|
20
|
Dow LE, Elsum IA, King CL, Kinross KM,
Richardson HE and Humbert PO: Loss of human Scribble cooperates
with H-Ras to promote cell invasion through deregulation of MAPK
signalling. Oncogene. 27:5988–6001. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Ling C, Zheng Y, Yin F, et al: The apical
transmembrane protein Crumbs functions as a tumor suppressor that
regulates Hippo signaling by binding to Expanded. Proc Natl Acad
Sci USA. 107:10532–10537. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Karp CM, Tan TT, Mathew R, et al: Role of
the polarity determinant crumbs in suppressing mammalian epithelial
tumor progression. Cancer Res. 68:4105–4115. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Athar U and Gentile TC: Treatment options
for metastatic renal cell carcinoma: a review. Can J Urol.
15:3954–3966. 2008.PubMed/NCBI
|
|
24
|
Cohen HT and McGovern FJ: Renal-cell
carcinoma. N Engl J Med. 353:2477–2490. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Kaelin WG Jr: Treatment of kidney cancer:
insights provided by the VHL tumor-suppressor protein. Cancer.
115(Suppl 10): S2262–S2272. 2009. View Article : Google Scholar
|
|
26
|
Kinouchi T, Kotake T, Mori Y and Abe T:
Human renal cell carcinoma: establishment and characterization of a
new cell line (OS-RC-2). In Vitro Cell Dev Biol. 21:195–199. 1985.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Fagerberg L, Hallström BM, Oksvold P, et
al: Analysis of the human tissue-specific expression by genome-wide
integration of transcriptomics and antibody-based proteomics. Mol
Cell Proteomics. 13:397–406. 2014. View Article : Google Scholar
|
|
28
|
Bulgakova NA and Knust E: The Crumbs
complex: from epithelial-cell polarity to retinal degeneration. J
Cell Sci. 122:2587–2596. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Makarova O, Roh MH, Liu CJ, Laurinec S and
Margolis B: Mammalian Crumbs3 is a small transmembrane protein
linked to protein associated with Lin-7 (Pals1). Gene. 302:21–29.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lemmers C, Michel D, Lane-Guermonprez L,
et al: CRB3 binds directly to Par6 and regulates the morphogenesis
of the tight junctions in mammalian epithelial cells. Mol Biol
Cell. 15:1324–1333. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lu H and Bilder D: Endocytic control of
epithelial polarity and proliferation in Drosophila. Nat Cell Biol.
7:1232–1239. 2005. View
Article : Google Scholar : PubMed/NCBI
|
|
32
|
Roeth JF, Sawyer JK, Wilner DA and Peifer
M: Rab11 helps maintain apical crumbs and adherens junctions in the
Drosophila embryonic ectoderm. PLoS One. 4:e76342009. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Thiery JP and Sleeman JP: Complex networks
orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell
Biol. 7:131–142. 2006. View
Article : Google Scholar : PubMed/NCBI
|
|
34
|
Aigner K, Dampier B, Descovich L, et al:
The transcription factor ZEB1 (deltaEF1) promotes tumour cell
dedifferentiation by repressing master regulators of epithelial
polarity. Oncogene. 26:6979–6988. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Whiteman EL, Liu CJ, Fearon ER and
Margolis B: The transcription factor snail represses Crumbs3
expression and disrupts apico-basal polarity complexes. Oncogene.
27:3875–3879. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Gilles C, Polette M, Mestdagt M, et al:
Transactivation of vimentin by beta-catenin in human breast cancer
cells. Cancer Res. 63:2658–2664. 2003.PubMed/NCBI
|
|
37
|
Onder TT, Gupta PB, Mani SA, Yang J,
Lander ES and Weinberg RA: Loss of E-cadherin promotes metastasis
via multiple downstream transcriptional pathways. Cancer Res.
68:3645–3654. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Stoops SL, Pearson AS, Weaver C, et al:
Identification and optimization of small molecules that restore
E-cadherin expression and reduce invasion in colorectal carcinoma
cells. ACS Chem Biol. 6:452–465. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Weng W, Yin J, Zhang Y, Qiu J and Wang X:
Metastasis-associated protein 1 promotes tumor invasion by
downregulation of E-cadherin. Int J Oncol. 44:812–818.
2014.PubMed/NCBI
|
|
40
|
Fogg VC, Liu CJ and Margolis B: Multiple
regions of Crumbs3 are required for tight junction formation in
MCF10A cells. J Cell Sci. 118:2859–2869. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Roh MH, Fan S, Liu CJ and Margolis B: The
Crumbs3-Pals1 complex participates in the establishment of polarity
in mammalian epithelial cells. J Cell Sci. 116:2895–2906. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Tunggal JA, Helfrich I, Schmitz A, et al:
E-cadherin is essential for in vivo epidermal barrier function by
regulating tight junctions. EMBO J. 24:1146–1156. 2005. View Article : Google Scholar : PubMed/NCBI
|
