Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 1019-6439 Online ISSN: 1791-2423
Journal Cover
February-2015 Volume 46 Issue 2

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
February-2015 Volume 46 Issue 2

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Review

Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)

  • Authors:
    • Nidhi Jariwala
    • Devaraja Rajasekaran
    • Jyoti Srivastava
    • Rachel Gredler
    • Maaged A. Akiel
    • Chadia L. Robertson
    • Luni Emdad
    • Paul B. Fisher
    • Devanand Sarkar
  • View Affiliations / Copyright

    Affiliations: Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA
  • Pages: 465-473
    |
    Published online on: November 18, 2014
       https://doi.org/10.3892/ijo.2014.2766
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

The staphylococcal nuclease and tudor domain containing 1 (SND1) is a multifunctional protein overexpressed in breast, prostate, colorectal and hepatocellular carcinomas and malignant glioma. Molecular studies have revealed the multifaceted activities of SND1 involved in regulating gene expression at transcriptional as well as post-transcriptional levels. Early studies identified SND1 as a transcriptional co-activator. SND1 is also a component of RNA-induced silencing complex (RISC) thus mediating RNAi function, a regulator of mRNA splicing, editing and stability, and plays a role in maintenance of cell viability. Such diverse actions allow the SND1 to modulate a complex array of molecular networks, thereby promoting carcinogenesis. Here, we describe the crucial role of SND1 in cancer development and progression, and highlight SND1 as a potential target for therapeutic intervention.
View Figures

Figure 1

Figure 2

View References

1 

Hanahan D and Weinberg RA: Hallmarks of cancer: the next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI

2 

Almendro V, Marusyk A and Polyak K: Cellular heterogeneity and molecular evolution in cancer. Annu Rev Pathol. 8:277–302. 2013. View Article : Google Scholar

3 

Callebaut I and Mornon JP: The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development. Biochem J. 321:125–132. 1997.PubMed/NCBI

4 

Yang J, Aittomaki S, Pesu M, et al: Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. EMBO J. 21:4950–4958. 2002. View Article : Google Scholar : PubMed/NCBI

5 

Gao X, Zhao X, Zhu Y, et al: Tudor staphylococcal nuclease (Tudor-SN) participates in small ribonucleoprotein (snRNP) assembly via interacting with symmetrically dimethylated Sm proteins. J Biol Chem. 287:18130–18141. 2012. View Article : Google Scholar : PubMed/NCBI

6 

Caudy AA, Ketting RF, Hammond SM, et al: A micrococcal nuclease homologue in RNAi effector complexes. Nature. 425:411–414. 2003. View Article : Google Scholar : PubMed/NCBI

7 

Paukku K, Kalkkinen N, Silvennoinen O, Kontula KK and Lehtonen JY: p100 increases AT1R expression through interaction with AT1R 3′-UTR. Nucleic Acids Res. 36:4474–4487. 2008. View Article : Google Scholar : PubMed/NCBI

8 

Paukku K, Yang J and Silvennoinen O: Tudor and nuclease-like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5. Mol Endocrinol. 17:1805–1814. 2003. View Article : Google Scholar : PubMed/NCBI

9 

Leverson JD, Koskinen PJ, Orrico FC, et al: Pim-1 kinase and p100 cooperate to enhance c-Myb activity. Mol Cell. 2:417–425. 1998. View Article : Google Scholar : PubMed/NCBI

10 

Garcia-Lopez J, de Hourcade JD and Del Mazo J: Reprogramming of microRNAs by adenosine-to-inosine editing and the selective elimination of edited microRNA precursors in mouse oocytes and preimplantation embryos. Nucleic Acids Res. 41:5483–5493. 2013. View Article : Google Scholar : PubMed/NCBI

11 

Li CL, Yang WZ, Chen YP and Yuan HS: Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing. Nucleic Acids Res. 36:3579–3589. 2008. View Article : Google Scholar : PubMed/NCBI

12 

Yoo BK, Santhekadur PK, Gredler R, et al: Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma. Hepatology. 53:1538–1548. 2011. View Article : Google Scholar : PubMed/NCBI

13 

Ho J, Kong JW, Choong LY, et al: Novel breast cancer metastasis-associated proteins. J Proteome Res. 8:583–594. 2009. View Article : Google Scholar

14 

Blanco MA, Aleckovic M, Hua Y, et al: Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions. J Biol Chem. 286:19982–19992. 2011. View Article : Google Scholar : PubMed/NCBI

15 

Wan L, Lu X, Yuan S, et al: MTDH- SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors. Cancer Cell. 26:92–105. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Santhekadur PK, Akiel M, Emdad L, et al: Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFbeta signaling. FEBS Open Bio. 4:353–361. 2014. View Article : Google Scholar

17 

Santhekadur PK, Das SK, Gredler R, et al: Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumor angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor kappaB and miR-221. J Biol Chem. 287:13952–13958. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Kuruma H, Kamata Y, Takahashi H, et al: Staphylococcal nuclease domain-containing protein 1 as a potential tissue marker for prostate cancer. Am J Pathol. 174:2044–2050. 2009. View Article : Google Scholar : PubMed/NCBI

19 

Tsuchiya N, Ochiai M, Nakashima K, Ubagai T, Sugimura T and Nakagama H: SND1, a component of RNA-induced silencing complex, is up-regulated in human colon cancers and implicated in early stage colon carcinogenesis. Cancer Res. 67:9568–9576. 2007. View Article : Google Scholar : PubMed/NCBI

20 

Emdad L, Janjic A, Al-Zubi M, et al: Suppression of miR-184 in malignant gliomas upregulates SND1 and promotes tumor aggressiveness. Neuro Oncol. Sep 12–2014.(Epub ahead of print). pii: nou220. View Article : Google Scholar : PubMed/NCBI

21 

Lienard P, Riviere M, Van Vooren P, Szpirer C and Szpirer J: Assignment of SND1, the gene encoding coactivator p100, to human chromosome 7q31.3 and rat chromosome 4q23 by in situ hybridization. Cytogenet Cell Genet. 90:253–254. 2000. View Article : Google Scholar : PubMed/NCBI

22 

Voeghtly LM, Mamula K, Campbell JL, Shriver CD and Ellsworth RE: Molecular alterations associated with breast cancer mortality. PLoS One. 7:e468142012. View Article : Google Scholar : PubMed/NCBI

23 

Jenkins RB, Qian J, Lee HK, et al: A molecular cytogenetic analysis of 7q31 in prostate cancer. Cancer Res. 58:759–766. 1998.PubMed/NCBI

24 

Glukhova L, Lavialle C, Fauvet D, et al: Mapping of the 7q31 subregion common to the small chromosome 7 derivatives from two sporadic papillary renal cell carcinomas: increased copy number and overexpression of the MET proto-oncogene. Oncogene. 19:754–761. 2000. View Article : Google Scholar : PubMed/NCBI

25 

Theobald DL, Mitton-Fry RM and Wuttke DS: Nucleic acid recognition by OB-fold proteins. Annu Rev Biophys Biomol Struct. 32:115–133. 2003. View Article : Google Scholar : PubMed/NCBI

26 

Ying M and Chen D: Tudor domain-containing proteins of Drosophila melanogaster. Dev Growth Differ. 54:32–43. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Armengol S, Arretxe E, Rodriguez L, Ochoa B, Chico Y and Martinez MJ: NF-kappaB, Sp1 and NF-Y as transcriptional regulators of human SND1 gene. Biochimie. 95:735–742. 2013. View Article : Google Scholar

28 

Rodriguez L, Bartolome N, Ochoa B and Martinez MJ: Isolation and characterization of the rat SND p102 gene promoter: putative role for nuclear factor-Y in regulation of transcription. Ann NY Acad Sci. 1091:282–295. 2006. View Article : Google Scholar

29 

Rodriguez L, Ochoa B and Martinez MJ: NF-Y and Sp1 are involved in transcriptional regulation of rat SND p102 gene. Biochem Biophys Res Commun. 356:226–232. 2007. View Article : Google Scholar : PubMed/NCBI

30 

Fashe T, Saarikettu J, Isomaki P, Yang J and Silvennoinen O: Expression analysis of Tudor-SN protein in mouse tissues. Tissue Cell. 45:21–31. 2013. View Article : Google Scholar

31 

Keenan TW, Winter S, Rackwitz HR and Heid HW: Nuclear coactivator protein p100 is present in endoplasmic reticulum and lipid droplets of milk secreting cells. Biochim Biophys Acta. 1523:84–90. 2000. View Article : Google Scholar : PubMed/NCBI

32 

Tong X, Drapkin R, Yalamanchili R, Mosialos G and Kieff E: The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE. Mol Cell Biol. 15:4735–4744. 1995.PubMed/NCBI

33 

Valineva T, Yang J, Palovuori R and Silvennoinen O: The transcriptional co-activator protein p100 recruits histone acetyl-transferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6. J Biol Chem. 280:14989–14996. 2005. View Article : Google Scholar

34 

Bromberg J: Stat proteins and oncogenesis. J Clin Invest. 109:1139–1142. 2002. View Article : Google Scholar : PubMed/NCBI

35 

Liu X, Dong L, Zhang X, et al: Identification of p100 target promoters by chromatin immunoprecipitation-guided ligation and selection (ChIP-GLAS). Cell Mol Immunol. 8:88–91. 2011. View Article : Google Scholar

36 

Sarkar D and Fisher PB: AEG-1/MTDH/LYRIC: clinical significance. Adv Cancer Res. 120:39–74. 2013. View Article : Google Scholar : PubMed/NCBI

37 

Yoo BK, Emdad L, Lee SG, et al: Astrocyte elevated gene-1 (AEG-1): A multifunctional regulator of normal and abnormal physiology. Pharmacol Ther. 130:1–8. 2011. View Article : Google Scholar : PubMed/NCBI

38 

Milochau A, Lagree V, Benassy MN, et al: Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. FEBS Lett. 588:2217–2222. 2014. View Article : Google Scholar : PubMed/NCBI

39 

Heinrich EM, Wagner J, Kruger M, et al: Regulation of miR-17-92a cluster processing by the microRNA binding protein SND1. FEBS Lett. 587:2405–2411. 2013. View Article : Google Scholar : PubMed/NCBI

40 

Gao X, Shi X, Fu X, et al: Human Tudor staphylococcal nuclease (Tudor-SN) protein modulates the kinetics of AGTR1–3′UTR granule formation. FEBS Lett. 588:2154–2161. 2014. View Article : Google Scholar : PubMed/NCBI

41 

Lei Y, Huang Y, Zhang H, Yu L, Zhang M and Dayton A: Functional interaction between cellular p100 and the dengue virus 3′ UTR. J Gen Virol. 92:796–806. 2011. View Article : Google Scholar

42 

Wahl MC, Will CL and Luhrmann R: The spliceosome: design principles of a dynamic RNP machine. Cell. 136:701–718. 2009. View Article : Google Scholar : PubMed/NCBI

43 

David CJ and Manley JL: Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev. 24:2343–2364. 2010. View Article : Google Scholar : PubMed/NCBI

44 

Yang J, Valineva T, Hong J, et al: Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. Nucleic Acids Res. 35:4485–4494. 2007. View Article : Google Scholar : PubMed/NCBI

45 

Cappellari M, Bielli P, Paronetto MP, et al: The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells. Oncogene. 33:3794–3802. 2014. View Article : Google Scholar

46 

Nishikura K: Functions and regulation of RNA editing by ADAR deaminases. Annu Rev Biochem. 79:321–349. 2010. View Article : Google Scholar : PubMed/NCBI

47 

Gao X, Ge L, Shao J, et al: Tudor-SN interacts with and co-localizes with G3BP in stress granules under stress conditions. FEBS Lett. 584:3525–3532. 2010. View Article : Google Scholar : PubMed/NCBI

48 

Weissbach R and Scadden AD: Tudor-SN and ADAR1 are components of cytoplasmic stress granules. RNA. 18:462–471. 2012. View Article : Google Scholar : PubMed/NCBI

49 

Sundstrom JF, Vaculova A, Smertenko AP, et al: Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. Nat Cell Biol. 11:1347–1354. 2009. View Article : Google Scholar : PubMed/NCBI

50 

El-Serag HB: Hepatocellular carcinoma. N Engl J Med. 365:1118–1127. 2011. View Article : Google Scholar : PubMed/NCBI

51 

Villanueva A, Hernandez-Gea V and Llovet JM: Medical therapies for hepatocellular carcinoma: a critical view of the evidence. Nat Rev Gastroenterol Hepatol. 10:34–42. 2013. View Article : Google Scholar

52 

Llovet JM, Ricci S, Mazzaferro V, et al: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 359:378–390. 2008. View Article : Google Scholar : PubMed/NCBI

53 

Yin J, Ding J, Huang L, et al: SND1 affects proliferation of hepatocellular carcinoma cell line SMMC-7721 by regulating IGFBP3 expression. Anat Rec. 296:1568–1575. 2013. View Article : Google Scholar

54 

Nguyen DX, Bos PD and Massague J: Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer. 9:274–284. 2009. View Article : Google Scholar : PubMed/NCBI

55 

Brown DM and Ruoslahti E: Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell. 5:365–374. 2004. View Article : Google Scholar : PubMed/NCBI

56 

Hu G, Chong RA, Yang Q, et al: MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. Cancer Cell. 15:9–20. 2009. View Article : Google Scholar :

57 

Yoo BK, Emdad L, Su ZZ, et al: Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. J Clin Invest. 119:465–477. 2009. View Article : Google Scholar : PubMed/NCBI

58 

Yoo BK, Chen D, Su ZZ, et al: Molecular mechanism of chemoresistance by astrocyte elevated gene-1. Cancer Res. 70:3249–3258. 2010. View Article : Google Scholar : PubMed/NCBI

59 

Emdad L, Lee SG, Su ZZ, et al: Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis. Proc Natl Acad Sci USA. 106:21300–21305. 2009. View Article : Google Scholar : PubMed/NCBI

60 

Liu W, Beck BH, Vaidya KS, et al: Metastasis suppressor KISS1 seems to reverse the Warburg effect by enhancing mitochondrial biogenesis. Cancer Res. 74:954–963. 2014. View Article : Google Scholar

61 

Quintana AM, Liu F, O’Rourke JP and Ness SA: Identification and regulation of c-Myb target genes in MCF-7 cells. BMC Cancer. 11:302011. View Article : Google Scholar : PubMed/NCBI

62 

Naumov VA, Generozov EV, Zaharjevskaya NB, et al: Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 8:921–934. 2013. View Article : Google Scholar : PubMed/NCBI

63 

Wang N, Du X, Zang L, et al: Prognostic impact of Metadherin-SND1 interaction in colon cancer. Mol Biol Rep. 39:10497–10504. 2012. View Article : Google Scholar : PubMed/NCBI

64 

Ostrom QT, Gittleman H, Farah P, et al: CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2006–2010. Neuro Oncol. 15:1–56. 2013. View Article : Google Scholar

65 

Wen PY and Kesari S: Malignant gliomas in adults. N Engl J Med. 359:492–507. 2008. View Article : Google Scholar : PubMed/NCBI

66 

Lefranc F, Brotchi J and Kiss R: Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol. 23:2411–2422. 2005. View Article : Google Scholar : PubMed/NCBI

67 

Stupp R, Mason WP, van den Bent MJ, et al: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 352:987–996. 2005. View Article : Google Scholar : PubMed/NCBI

68 

Hossain MJ, Korde R, Singh S, et al: Tudor domain proteins in protozoan parasites and characterization of Plasmodium falciparum tudor staphylococcal nuclease. Int J Parasitol. 38:513–526. 2008. View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Jariwala N, Rajasekaran D, Srivastava J, Gredler R, Akiel MA, Robertson CL, Emdad L, Fisher PB and Sarkar D: Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review). Int J Oncol 46: 465-473, 2015.
APA
Jariwala, N., Rajasekaran, D., Srivastava, J., Gredler, R., Akiel, M.A., Robertson, C.L. ... Sarkar, D. (2015). Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review). International Journal of Oncology, 46, 465-473. https://doi.org/10.3892/ijo.2014.2766
MLA
Jariwala, N., Rajasekaran, D., Srivastava, J., Gredler, R., Akiel, M. A., Robertson, C. L., Emdad, L., Fisher, P. B., Sarkar, D."Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)". International Journal of Oncology 46.2 (2015): 465-473.
Chicago
Jariwala, N., Rajasekaran, D., Srivastava, J., Gredler, R., Akiel, M. A., Robertson, C. L., Emdad, L., Fisher, P. B., Sarkar, D."Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)". International Journal of Oncology 46, no. 2 (2015): 465-473. https://doi.org/10.3892/ijo.2014.2766
Copy and paste a formatted citation
x
Spandidos Publications style
Jariwala N, Rajasekaran D, Srivastava J, Gredler R, Akiel MA, Robertson CL, Emdad L, Fisher PB and Sarkar D: Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review). Int J Oncol 46: 465-473, 2015.
APA
Jariwala, N., Rajasekaran, D., Srivastava, J., Gredler, R., Akiel, M.A., Robertson, C.L. ... Sarkar, D. (2015). Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review). International Journal of Oncology, 46, 465-473. https://doi.org/10.3892/ijo.2014.2766
MLA
Jariwala, N., Rajasekaran, D., Srivastava, J., Gredler, R., Akiel, M. A., Robertson, C. L., Emdad, L., Fisher, P. B., Sarkar, D."Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)". International Journal of Oncology 46.2 (2015): 465-473.
Chicago
Jariwala, N., Rajasekaran, D., Srivastava, J., Gredler, R., Akiel, M. A., Robertson, C. L., Emdad, L., Fisher, P. B., Sarkar, D."Role of the staphylococcal nuclease and tudor domain containing 1 in oncogenesis (Review)". International Journal of Oncology 46, no. 2 (2015): 465-473. https://doi.org/10.3892/ijo.2014.2766
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team