|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Nagini S: Carcinoma of the stomach: a
review of epidemiology, pathogenesis, molecular genetics and
chemoprevention. World J Gastrointest Oncol. 4:156–169. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Zasloff M: Antimicrobial peptides of
multicellular organisms. Nature. 415:389–395. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Papo N and Shai Y: Host defense peptides
as new weapons in cancer treatment. Cell Mol Life Sci. 62:784–790.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Paredes-Gamero EJ, Martins MN, Cappabianco
FA, Ide JS and Miranda A: Characterization of dual effects induced
by antimicrobial peptides: regulated cell death or membrane
disruption. Biochim Biophys Acta. 1820:1062–1072. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Jin X, Mei H, Li X, Ma Y, Zeng A, Wang Y,
Lu X, Chu F, Wu Q and Zhu J: Apoptosis-inducing activity of the
antimicrobial peptide cecropin of Musca domestica in human
hepatocellular carcinoma cell line BEL-7402 and the possible
mechanism. Acta Biochim Biophys Sin. 42:259–265. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Wang C, Zhou Y, Li S, Li HB, Tian LL, Wang
H and Shang DJ: Anticancer mechanisms of temporin-1CEa, an
amphipathic α-helical antimicrobial peptide, in Bcap-37 human
breast cancer cells. Life Sci. 92:1004–1014. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Risso A, Braidot E, Sordan MC, Vianello A,
Macrì F, Skerlavaj B, Zanetti M, Gennaro R and Bernardi P: BMAP-28,
an antibiotic peptide of innate immunity, induces cell death
through opening of the mitochondrial permeability transition pore.
Mol Cell Biol. 22:1926–1935. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Sun KW, Ma YY, Guan TP, Xia YJ, Shao CM,
Chen LG, Ren YJ, Yao HB, Yang Q and He XJ: Oridonin induces
apoptosis in gastric cancer through Apaf-1, cytochrome c and
caspase-3 signaling pathway. World J Gastroenterol. 18:7166–7174.
2012. View Article : Google Scholar
|
|
10
|
Furlong SJ, Mader JS and Hoskin DW: Bovine
lactoferricin induces caspase-independent apoptosis in human
B-lymphoma cells and extends the survival of immune-deficient mice
bearing B-lymphoma xenografts. Exp Mol Pathol. 88:371–375. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chen YL, Li JH, Yu CY, Lin CJ, Chiu PH,
Chen PW, Lin CC and Chen WJ: Novel cationic antimicrobial peptide
GW-H1 induced caspase-dependent apoptosis of hepatocellular
carcinoma cell lines. Peptides. 36:257–265. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Huh JE, Kang JW, Nam D, Baek YH, Choi DY,
Park DS and Lee JD: Melittin suppresses VEGF-A-induced tumor growth
by blocking VEGFR-2 and the COX-2-mediated MAPK signaling pathway.
J Nat Prod. 75:1922–1929. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang C, Chen T, Zhang N, Yang M, Li B, Lü
X, Cao X and Ling C: Melittin, a major component of bee venom,
sensitizes human hepatocellular carcinoma cells to tumor necrosis
factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis
by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha
kinase-NFkappaB. J Biol Chem. 284:3804–3813. 2009. View Article : Google Scholar
|
|
14
|
Xu XX, Jiang HR, Li HB, Zhang TN, Zhou Q
and Liu N: Apoptosis of stomach cancer cell SGC-7901 and regulation
of Akt signaling way induced by bovine lactoferrin. J Dairy Sci.
93:2344–2350. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Jeong YJ, Choi Y, Shin JM, et al: Melittin
suppresses EGF-induced cell motility and invasion by inhibiting
PI3K/Akt/mTOR signaling pathway in breast cancer cells. Food Chem
Toxicol. 68:218–225. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Fan Q, Hu Y, Pang H, Sun J, Wang Z and Li
J: Melittin protein inhibits the proliferation of MG63 cells by
activating inositol-requiring protein-1α and X-box binding protein
1-mediated apoptosis. Mol Med Rep. 9:1365–1370. 2014.PubMed/NCBI
|
|
17
|
Ting CH, Huang HN, Huang TC, Wu CJ and
Chen JY: The mechanisms by which pardaxin, a natural cationic
antimicrobial peptide, targets the endoplasmic reticulum and
induces c-FOS. Biomaterials. 35:3627–3640. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Song CC, Lu X, Cheng BB, DU J, Li B and
Ling CQ: Effects of melittin on growth and angiogenesis of human
hepatocellular carcinoma BEL-7402 cell xenografts in nude mice. Ai
Zheng. 26:1315–1322. 2007.(In Chinese). PubMed/NCBI
|
|
19
|
Li J, Zhang F and Ma Z: Prokaryotic
expression of cecropin gene isolated from the silk worm Bombyx mori
Xinjiang race and antibacterial activity of fusion cecropin. Acta
Entomol Sin. 47:407–411. 2004.(In Chinese).
|
|
20
|
Liu Z, Zhang F, Cai L, Zhao G and Wang B:
Studies on the properties of cecropin-XJ expressed in yeast from
Xinjiang silkworm. Wei Sheng Wu Xue Bao. 43:635–641. 2003.(In
Chinese).
|
|
21
|
Wu Y, Xia L and Zhang F: Inhibition of
CecropinXJ on proliferation of human gastric cancer AGS cells.
Chinese J Cell Biol. 36:1355–1361. 2014.(In Chinese).
|
|
22
|
Xia L, Zhang F, Liu Z, Ma J and Yang J:
Expression and characterization of cecropinXJ, a bioactive
antimicrobial peptide from Bombyx mori (Bombycidae, Lepidoptera) in
Escherichia coli. Exp Ther Med. 5:1745–1751. 2013.PubMed/NCBI
|
|
23
|
Xia L, Liu Z, Ma J, Sun S, Yang J and
Zhang F: Expression, purification and characterization of cecropin
antibacterial peptide from Bombyx mori in Saccharomyces cerevisiae.
Protein Expr Purif. 90:47–54. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Shai Y: Mechanism of the binding,
insertion and destabilization of phospholipid bilayer membranes by
alpha-helical antimicrobial and cell non-selective membrane-lytic
peptides. Biochim Biophys Acta. 1462:55–70. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mahassni SH and Al-Reemi RM: Apoptosis and
necrosis of human breast cancer cells by an aqueous extract of
garden cress (Lepidium sativum) seeds. Saudi J Biol Sci.
20:131–139. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Cerón JM, Contreras-Moreno J, Puertollano
E, de Cienfuegos GÁ, Puertollano MA and de Pablo MA: The
antimicrobial peptide cecropin A induces caspase-independent cell
death in human promyelocytic leukemia cells. Peptides.
31:1494–1503. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Jeong JC, Jang SW, Kim TH, Kwon CH and Kim
YK: Mulberry fruit (Moris fructus) extracts induce human glioma
cell death in vitro through ROS-dependent mitochondrial pathway and
inhibits glioma tumor growth in vivo. Nutr Cancer. 62:402–412.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
She EX and Hao Z: A novel piperazine
derivative potently induces caspase-dependent apoptosis of cancer
cells via inhibition of multiple cancer signaling pathways. Am J
Transl Res. 5:622–633. 2013.PubMed/NCBI
|
|
29
|
Bao R, Shu Y, Wu X, et al: Oridonin
induces apoptosis and cell cycle arrest of gallbladder cancer cells
via the mitochondrial pathway. BMC Cancer. 14:2172014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Folkman J: What is the evidence that
tumors are angiogenesis dependent? J Natl Cancer Inst. 82:4–6.
1990. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Orditura M, Galizia G, Sforza V, et al:
Treatment of gastric cancer. World J Gastroenterol. 20:1635–1649.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Garnier-Suillerot A, Marbeuf-Gueye C,
Salerno M, Loetchutinat C, Fokt I, Krawczyk M, Kowalczyk T and
Priebe W: Analysis of drug transport kinetics in
multidrug-resistant cells: implications for drug action. Curr Med
Chem. 8:51–64. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Moore AJ, Devine DA and Bibby MC:
Preliminary experimental anticancer activity of cecropins. Pept
Res. 7:265–269. 1994.PubMed/NCBI
|
|
34
|
Suttmann H, Retz M, Paulsen F, Harder J,
Zwergel U, Kamradt J, Wullich B, Unteregger G, Stöckle M and
Lehmann J: Antimicrobial peptides of the Cecropin-family show
potent antitumor activity against bladder cancer cells. BMC Urol.
8:52008. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Jin XB, Wang YJ, Liang LL, Pu QH, Shen J,
Lu XM, Chu FJ and Zhu JY: Cecropin suppresses human hepatocellular
carcinoma BEL-7402 cell growth and survival in vivo without
side-toxicity. Asian Pac J Cancer Prev. 15:5433–5436. 2014.
View Article : Google Scholar
|
|
36
|
Boman HG: Antibacterial peptides: basic
facts and emerging concepts. J Intern Med. 254:197–215. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zhang WM, Lai ZS, He MR, Xu G, Huang W and
Zhou DY: Effects of the antibacterial peptide cecropins from
Chinese oak silkworm, antheraea pernyi on 1,
2-dimethylhydrazine-induced colon carcinogenesis in rats. Di Yi Jun
Yi Da Xue Xue Bao. 23:1066–1068. 2003.(In Chinese). PubMed/NCBI
|
|
38
|
Hui L, Leung K and Chen HM: The combined
effects of antibacterial peptide cecropin A and anti-cancer agents
on leukemia cells. Anticancer Res. 22:2811–2816. 2002.
|
|
39
|
Harris F, Dennison SR, Singh J and Phoenix
DA: On the selectivity and efficacy of defense peptides with
respect to cancer cells. Med Res Rev. 33:190–234. 2013. View Article : Google Scholar
|
|
40
|
Wang C, Tian LL, Li S, Li HB, Zhou Y, Wang
H, Yang QZ, Ma LJ and Shang DJ: Rapid cytotoxicity of antimicrobial
peptide Tempoprin-1CEa in breast cancer cells through membrane
destruction and intracellular calcium mechanism. PLoS One.
8:e604622013. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Lee JH, Kim IW, Kim SH, Yun EY, Nam SH,
Ahn MY, Kang DC and Hwang JS: Anticancer activity of CopA3 dimer
peptide in human gastric cancer cells. BMB Rep. Jul 22–2014.(Epub
ahead of print).
|
|
42
|
Huang TC, Lee JF and Chen JY: Pardaxin, an
antimicrobial peptide, triggers caspase-dependent and ROS-mediated
apoptosis in HT-1080 cells. Mar Drugs. 9:1995–2009. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Tsujimoto Y: Bcl-2 family of proteins:
life-or-death switch in mitochondria. Biosci Rep. 22:47–58. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Du L, Mei HF, Yin X and Xing YQ: Delayed
growth of glioma by a polysaccharide from Aster tataricus involve
upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and
downregulation of the Akt. Tumour Biol. 35:1819–1825. 2014.
View Article : Google Scholar
|
|
45
|
Das A, Banik NL, Patel SJ and Ray SK:
Dexamethasone protected human glioblastoma U87MG cells from
temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and
preventing proteolytic activities. Mol Cancer. 3:362004. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Gajski G and Garaj-Vrhovac V: Melittin: a
lytic peptide with anticancer properties. Environ Toxicol
Pharmacol. 36:697–705. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Emmett MS, Dewing D and Pritchard-Jones
RO: Angiogenesis and melanoma: from basic science to clinical
trials. Am J Cancer Res. 1:852–868. 2011.
|
|
48
|
Folkman J: Role of angiogenesis in tumor
growth and metastasis. Semin Oncol. 29:15–18. 2002. View Article : Google Scholar
|
|
49
|
Javle M, Smyth EC and Chau I: Ramucirumab:
successfully targeting angiogenesis in gastric cancer. Clin Cancer
Res. 20:5875–5881. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Presta M, Dell’Era P, Mitola S, Moroni E,
Ronca R and Rusnati M: Fibroblast growth factor/fibroblast growth
factor receptor system in angiogenesis. Cytokine Growth Factor Rev.
16:159–178. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Starke RD, Ferraro F, Paschalaki KE, et
al: Endothelial von Willebrand factor regulates angiogenesis.
Blood. 117:1071–1080. 2011. View Article : Google Scholar :
|
|
52
|
Aoyagi K, Kouhuji K, Kizaki J, Isobe T,
Hashimoto K and Shirouzu K: Molecular targeting to treat gastric
cancer. World J Gastroenterol. 20:13741–13755. 2014. View Article : Google Scholar : PubMed/NCBI
|
