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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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December-2015 Volume 47 Issue 6

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Review

The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review)

  • Authors:
    • Xuan Wang
    • Hongwei Zhang
    • Taihong Wang
    • Wan Yee Lau
    • Xin Wang
    • Jingfeng Sun
    • Zhenhua Yuan
    • Yewei Zhang
  • View Affiliations / Copyright

    Affiliations: Department of Hepatobiliary and Pancreatic Surgery, Affiliated Jiangsu Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu 210009, P.R. China, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, P.R. China, Department of Oncology, Affiliated Jiangsu Cancer Hospital of Nanjing Medical University, Nanjing, Jiangsu 210009, P.R. China
  • Pages: 2017-2027
    |
    Published online on: October 6, 2015
       https://doi.org/10.3892/ijo.2015.3190
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Abstract

Pancreatic head cancer is a common but the most lethal cancer of the human digestive system. It is invasive, resulting in early infiltration of adjacent structures and lymph node and distant metastases. Its biological characteristics of neurotropic growth lead to early neural invasion (NI) which is an independent prognostic factor of survival for pancreatic cancer. Radical surgical resection remains the only form of curative treatment. The extent of surgical resection and whether extended resection results in better long-term survival have been controversial. Studies have reported that peripancreatic plexus invasion is a frequent cause of pancreatic cancer recurrence and death. The relationship between cancer microenvironment and nerve cells, and whether the peripancreatic nerve plexus nearby needs to be resected require further studies. The present review aims to discuss the role of peripancreatic nerve and its implications in pancreatic head cancer resection.
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Copy and paste a formatted citation
Spandidos Publications style
Wang X, Zhang H, Wang T, Lau WY, Wang X, Sun J, Yuan Z and Zhang Y: The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review). Int J Oncol 47: 2017-2027, 2015.
APA
Wang, X., Zhang, H., Wang, T., Lau, W.Y., Wang, X., Sun, J. ... Zhang, Y. (2015). The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review). International Journal of Oncology, 47, 2017-2027. https://doi.org/10.3892/ijo.2015.3190
MLA
Wang, X., Zhang, H., Wang, T., Lau, W. Y., Wang, X., Sun, J., Yuan, Z., Zhang, Y."The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review)". International Journal of Oncology 47.6 (2015): 2017-2027.
Chicago
Wang, X., Zhang, H., Wang, T., Lau, W. Y., Wang, X., Sun, J., Yuan, Z., Zhang, Y."The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review)". International Journal of Oncology 47, no. 6 (2015): 2017-2027. https://doi.org/10.3892/ijo.2015.3190
Copy and paste a formatted citation
x
Spandidos Publications style
Wang X, Zhang H, Wang T, Lau WY, Wang X, Sun J, Yuan Z and Zhang Y: The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review). Int J Oncol 47: 2017-2027, 2015.
APA
Wang, X., Zhang, H., Wang, T., Lau, W.Y., Wang, X., Sun, J. ... Zhang, Y. (2015). The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review). International Journal of Oncology, 47, 2017-2027. https://doi.org/10.3892/ijo.2015.3190
MLA
Wang, X., Zhang, H., Wang, T., Lau, W. Y., Wang, X., Sun, J., Yuan, Z., Zhang, Y."The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review)". International Journal of Oncology 47.6 (2015): 2017-2027.
Chicago
Wang, X., Zhang, H., Wang, T., Lau, W. Y., Wang, X., Sun, J., Yuan, Z., Zhang, Y."The concept and controversy of retroperitoneal nerve dissection in pancreatic head carcinoma (Review)". International Journal of Oncology 47, no. 6 (2015): 2017-2027. https://doi.org/10.3892/ijo.2015.3190
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