|
1
|
Keith B and Simon MC: Hypoxia-inducible
factors, stem cells, and cancer. Cell. 129:465–472. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Harris AL: Hypoxia - a key regulatory
factor in tumour growth. Nat Rev Cancer. 2:38–47. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Folkman J: Angiogenesis in cancer,
vascular, rheumatoid and other disease. Nat Med. 1:27–31. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Rich J, Borton A and Wang X: Transforming
growth factor-beta signaling in cancer. Microsc Res Tech.
52:363–373. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Sánchez-Elsner T, Botella LM, Velasco B,
Corbí A, Attisano L and Bernabéu C: Synergistic cooperation between
hypoxia and transforming growth factor-beta pathways on human
vascular endothelial growth factor gene expression. J Biol Chem.
276:38527–38535. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Reya T, Morrison SJ, Clarke MF and
Weissman IL: Stem cells, cancer, and cancer stem cells. Nature.
414:105–111. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Boyer LA, Lee TI, Cole MF, Johnstone SE,
Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG,
et al: Core transcriptional regulatory circuitry in human embryonic
stem cells. Cell. 122:947–956. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Yu F, Li J, Chen H, Fu J, Ray S, Huang S,
Zheng H and Ai W: Kruppel-like factor 4 (KLF4) is required for
maintenance of breast cancer stem cells and for cell migration and
invasion. Oncogene. 30:2161–2172. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Baumann M, Krause M and Hill R: Exploring
the role of cancer stem cells in radioresistance. Nat Rev Cancer.
8:545–554. 2008. View
Article : Google Scholar : PubMed/NCBI
|
|
10
|
Jemal A, Siegel R, Ward E, Hao Y, Xu J,
Murray T and Thun MJ: Cancer statistics, 2008. CA Cancer J Clin.
58:71–96. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
DeSantis C, Siegel R and Jemal A: Breast
cancer facts and figures 2007–2008. Amer Can Soc. 1–32. 2008.
|
|
12
|
Limer JL and Speirs V: Phytooestrogens and
breast cancer chemoprevention. Breast Cancer Res. 6:119–127. 2004.
View Article : Google Scholar :
|
|
13
|
Privat C, Telo JP, Bernardes-Genisson V,
Vieira A, Souchard JP and Nepveu F: Antioxidant properties of
trans-epsilon-viniferin as compared to stilbene derivatives in
aqueous and nonaqueous media. J Agric Food Chem. 50:1213–1217.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Kong AN, Yu R, Hebbar V, Chen C, Owuor E,
Hu R, Ee R and Mandlekar S: Signal transduction events elicited by
cancer prevention compounds. Mutat Res. 480–481:231–241. 2001.
View Article : Google Scholar
|
|
15
|
Jeong SH, Jo WS, Song S, Suh H, Seol SY,
Leem SH, Kwon TK and Yoo YH: A novel resveratrol derivative,
HS1793, overcomes the resistance conferred by Bcl-2 in human
leukemic U937 cells. Biochem Pharmacol. 77:1337–1347. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Raleigh JA, Miller GG, Franko AJ, Koch CJ,
Fuciarelli AF and Kelly DA: Fluorescence immunohistochemical
detection of hypoxic cells in spheroids and tumours. Br J Cancer.
56:395–400. 1987. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Rijken PF, Bernsen HJ, Peters JP, Hodgkiss
RJ, Raleigh JA and van der Kogel AJ: Spatial relationship between
hypoxia and the (perfused) vascular network in a human glioma
xenograft: A quantitative multi-parameter analysis. Int J Radiat
Oncol Biol Phys. 48:571–582. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Raleigh JA, Franko AJ, Treiber EO, Lunt JA
and Allen PS: Covalent binding of a fluorinated 2-nitroimidazole to
EMT-6 tumors in Balb/C mice: Detection by F-19 nuclear magnetic
resonance at 2.35 T. Int J Radiat Oncol Biol Phys. 12:1243–1245.
1986. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Bernsen HJ, Rijken PF, Hagemeier NE and
van der Kogel AJ: A quantitative analysis of vascularization and
perfusion of human glioma xenografts at different implantation
sites. Microvasc Res. 57:244–257. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Durand RE and Raleigh JA: Identification
of nonproliferating but viable hypoxic tumor cells in vivo. Cancer
Res. 58:3547–3550. 1998.PubMed/NCBI
|
|
21
|
Garvin S, Ollinger K and Dabrosin C:
Resveratrol induces apoptosis and inhibits angiogenesis in human
breast cancer xenografts in vivo. Cancer Lett. 231:113–122. 2006.
View Article : Google Scholar
|
|
22
|
Jeong MH, Yang KM, Choi YJ, Kim SD, Yoo
YH, Seo SY, Lee SH, Ryu SR, Lee CM, Suh H, et al: Resveratrol
analog, HS-1793 enhance anti-tumor immunity by reducing the
CD4+CD25+ regulatory T cells in FM3A tumor
bearing mice. Int Immunopharmacol. 14:328–333. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Jögi A, Øra I, Nilsson H, Lindeheim A,
Makino Y, Poellinger L, Axelson H and Påhlman S: Hypoxia alters
gene expression in human neuroblastoma cells toward an immature and
neural crest-like phenotype. Proc Natl Acad Sci USA. 99:7021–7026.
2002. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Tavaluc RT, Hart LS, Dicker DT and
El-Deiry WS: Effects of low confluency, serum starvation and
hypoxia on the side population of cancer cell lines. Cell Cycle.
6:2554–2562. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Giuntoli S, Rovida E, Gozzini A, Barbetti
V, Cipolleschi MG, Olivotto M and Dello Sbarba P: Severe hypoxia
defines heterogeneity and selects highly immature progenitors
within clonal erythroleukemia cells. Stem Cells. 25:1119–1125.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Das B, Tsuchida R, Malkin D, Koren G,
Baruchel S and Yeger H: Hypoxia enhances tumor stemness by
increasing the invasive and tumorigenic side population fraction.
Stem Cells. 26:1818–1830. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
McCord AM, Jamal M, Shankavaram UT, Lang
FF, Camphausen K and Tofilon PJ: Physiologic oxygen concentration
enhances the stem-like properties of CD133+ human
glioblastoma cells in vitro. Mol Cancer Res. 7:489–497. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Vaupel P: The role of hypoxia-induced
factors in tumor progression. Oncologist. 9(Suppl 5): 10–17. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Ryan HE, Poloni M, McNulty W, Elson D,
Gassmann M, Arbeit JM and Johnson RS: Hypoxia-inducible
factor-1alpha is a positive factor in solid tumor growth. Cancer
Res. 60:4010–4015. 2000.PubMed/NCBI
|
|
30
|
Brizel DM, Scully SP, Harrelson JM,
Layfield LJ, Bean JM, Prosnitz LR and Dewhirst MW: Tumor
oxygenation predicts for the likelihood of distant metastases in
human soft tissue sarcoma. Cancer Res. 56:941–943. 1996.PubMed/NCBI
|
|
31
|
Bergers G and Benjamin LE: Tumorigenesis
and the angiogenic switch. Nat Rev Cancer. 3:401–410. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Zagzag D, Zhong H, Scalzitti JM, Laughner
E, Simons JW and Semenza GL: Expression of hypoxia-inducible factor
1alpha in brain tumors: Association with angiogenesis, invasion,
and progression. Cancer. 88:2606–2618. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Brown NS, Jones A, Fujiyama C, Harris AL
and Bicknell R: Thymidine phosphorylase induces carcinoma cell
oxidative stress and promotes secretion of angiogenic factors.
Cancer Res. 60:6298–6302. 2000.PubMed/NCBI
|
|
34
|
Benckert C, Jonas S, Cramer T, Von
Marschall Z, Schäfer G, Peters M, Wagner K, Radke C, Wiedenmann B,
Neuhaus P, et al: Transforming growth factor beta 1 stimulates
vascular endothelial growth factor gene transcription in human
cholangiocellular carcinoma cells. Cancer Res. 63:1083–1092.
2003.PubMed/NCBI
|
|
35
|
Ferrara N, Gerber HP and LeCouter J: The
biology of VEGF and its receptors. Nat Med. 9:669–676. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Zhang Q, Tang X, Lu QY, Zhang ZF, Brown J
and Le AD: Resveratrol inhibits hypoxia-induced accumulation of
hypoxia-inducible factor-1alpha and VEGF expression in human tongue
squamous cell carcinoma and hepatoma cells. Mol Cancer Ther.
4:1465–1474. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Conley SJ, Gheordunescu E, Kakarala P,
Newman B, Korkaya H, Heath AN, Clouthier SG and Wicha MS:
Antiangiogenic agents increase breast cancer stem cells via the
generation of tumor hypoxia. Proc Natl Acad Sci USA. 109:2784–2789.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Schwab LP, Peacock DL, Majumdar D, Ingels
JF, Jensen LC, Smith KD, Cushing RC and Seagroves TN:
Hypoxia-inducible factor 1α promotes primary tumor growth and
tumor-initiating cell activity in breast cancer. Breast Cancer Res.
14:R62012. View Article : Google Scholar
|
|
39
|
Li Z, Bao S, Wu Q, Wang H, Eyler C,
Sathornsumetee S, Shi Q, Cao Y, Lathia J, McLendon RE, et al:
Hypoxia-inducible factors regulate tumorigenic capacity of glioma
stem cells. Cancer Cell. 15:501–513. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Rosen EM, Fan S, Rockwell S and Goldberg
ID: The molecular and cellular basis of radiosensitivity:
Implications for understanding how normal tissues and tumors
respond to therapeutic radiation. Cancer Invest. 17:56–72. 1999.
View Article : Google Scholar
|
|
41
|
Camphausen K and Tofilon PJ: Combining
radiation and molecular targeting in cancer therapy. Cancer Biol
Ther. 3:247–250. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Moeller BJ, Cao Y, Li CY and Dewhirst MW:
Radiation activates HIF-1 to regulate vascular radiosensitivity in
tumors: Role of reoxygenation, free radicals, and stress granules.
Cancer Cell. 5:429–441. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Dewhirst MW, Cao Y and Moeller B: Cycling
hypoxia and free radicals regulate angiogenesis and radiotherapy
response. Nat Rev Cancer. 8:425–437. 2008. View Article : Google Scholar : PubMed/NCBI
|
