[Corrigendum] Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma
Affiliations: Department of Minimally Invasive Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P.R. China
- Published online on: October 24, 2016 https://doi.org/10.3892/ijo.2016.3749
- Pages: 340-340
Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Int J Oncol 42: [Related article:] 690–698, 2013
Following the publication of this article, an interested reader drew to our attention anomalies associated with the data shown in Fig. 2, which presented the mRNA and protein expression levels of tropomyosin 1 (TPM1) in HuCCT1 cells. Essentially, the control bands for α-tubulin had been duplicated across from Fig. 2A to Fig. 2B, and from Fig. 2D to Fig. 2E [the experiments showing treatment of the cells with (A) manumycin A, (B) U0126, (D) 5-aza-2-deoxycytidine (DAC) and (E) trichostatin A (TSA)], respectively. After having re-examined our original data, we realize that the figure was compiled incorrectly, and have returned to our source data. A corrected version of Fig. 2 is presented here, showing the correct control α-tubulin data for Fig. 2A and E, as they ought to have appeared. This error did not overall affect the conclusions reported in the study. We sincerely apologize for this mistake, and thank the reader of our article who drew this matter to our attention. Furthermore, we regret any inconvenience this mistake has caused.
TPM1 mRNA expression and protein expression in HuCCT1 cells. (A) HuCCT1 cells were treated with 5 and 10 µmol/l manumycin A for 24 h. (B) HuCCT1 cells were treated with 5 and 10 µmol/l U0126 for 24 h. (C) HuCCT1 cells were treated with 20 and 50 µmol/l LY294002 for 24 h. (D) HuCCT1 cells were treated with 1 and 5 µmol/l DAC for 24 h. (E) HuCCT1 cells were treated with 0.1 and 0.25 μmol/l TSA for 24 h. *P<0.05. TPM1, tropomyosin 1; DAC, 5-aza-2-deoxycytidine; TSA, trichostatin A.