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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2017 Volume 50 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

Sara Häggblad Sahlberg, Anja C. Mortensen, Jakob Haglöf, Mikael K.R. Engskog, Torbjörn Arvidsson, Curt Pettersson, Bengt Glimelius, Bo Stenerlöw, Marika Nestor
Pages: 5-14
Published online on: 18 November 2016

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Article Open Access

Inhibition of CDH17 gene expression via RNA interference reduces proliferation and apoptosis of human MKN28 gastric cancer cells

Rui Li, Hong‑Qiang Yang, Hai‑Lin Xi, Su Feng, Rui‑Hao Qin
Pages: 15-22
Published online on: 28 November 2016

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Article Open Access

AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway

Masayuki Morishita, Teruya Kawamoto, Hitomi Hara, Yasuo Onishi, Takeshi Ueha, Masaya Minoda, Etsuko Katayama, Toshiyuki Takemori, Naomasa Fukase, Masahiro Kurosaka, Ryosuke Kuroda, Toshihiro Akisue
Pages: 23-30
Published online on: 21 November 2016

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Article Open Access

Stathmin1 overexpression in hypopharyngeal squamous cell carcinoma: A new promoter in FaDu cell proliferation and migration

Yan Chen, Qicheng Zhang, Chuanjin Ding, Xiaobo Zhang, Xiaoxia Qiu, Zhenxin Zhang
Pages: 31-40
Published online on: 23 November 2016

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Article Open Access

Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment

Mariko Hirai, Hiroko Kitahara, Yutaka Kobayashi, Koroku Kato, George Bou-Gharios, Hiroyuki Nakamura, Shuichi Kawashiri
Pages: 41-48
Published online on: 02 December 2016

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Article Open Access

Long-term exposure of MCF-7 breast cancer cells to ethanol stimulates oncogenic features

Robert Gelfand, Dolores Vernet, Kevin W. Bruhn, Suren Sarkissyan, David Heber, Jaydutt V. Vadgama, Nestor F. Gonzalez-Cadavid
Pages: 49-65
Published online on: 09 December 2016

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Article Open Access

Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers

Suni Lee, Hidenori Matsuzaki, Megumi Maeda, Shoko Yamamoto, Naoko Kumagai-Takei, Tamayo Hatayama, Miho Ikeda, Kei Yoshitome, Yasumitsu Nishimura, Takemi Otsuki
Pages: 66-74
Published online on: 22 November 2016

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Article

Enzalutamide inhibits proliferation of gemcitabine-resistant bladder cancer cells with increased androgen receptor expression

Koji Kameyama, Kengo Horie, Kosuke Mizutani, Taku Kato, Yasunori Fujita, Kyojiro Kawakami, Toshio Kojima, Tatsuhiko Miyazaki, Takashi Deguchi, Masafumi Ito
Pages: 75-84
Published online on: 24 November 2016

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Article

Pro-metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-Tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Pages: 85-92
Published online on: 08 December 2016

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Article

Baicalin attenuates DDP (cisplatin) resistance in lung cancer by downregulating MARK2 and p-Akt

Zhiwei Xu, Ju Mei, Yan Tan
Pages: 93-100
Published online on: 15 November 2016

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Article

Tetrandrine inhibits glioma stem-like cells by repressing β-catenin expression

Yong Zhang, Yu-Lin Wen, Ji-Wei Ma, Jie-Cheng Ye, Xiao Wang, Jian-Xian Huang, Chao-Yue Meng, Xiao-Ze Xu, Shao-Xiang Wang, Xue-Yun Zhong
Pages: 101-110
Published online on: 23 November 2016

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Article

Oridonin inhibition and miR‑200b‑3p/ZEB1 axis in human pancreatic cancer

Zhifang Gui, Feng Luo, Yayang Yang, Can Shen, Shuquan Li, Jian Xu
Pages: 111-120
Published online on: 18 November 2016

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Article

Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells

Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Hong Ji, Yiming Li, Xijuan Cui, Ya'an Kang
Pages: 121-128
Published online on: 23 November 2016

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Article

Differential detection of cytoplasmic Wilms tumor 1 expression by immunohistochemistry, western blotting and mRNA quantification

Takehiro Maki, Hiroaki Ikeda, Aki Kuroda, Noriaki Kyogoku, Yoshiyuki Yamamura, Yukiko Tabata, Takehiro Abiko, Takahiro Tsuchikawa, Yasuhiro Hida, Toshiaki Shichinohe, Eiichi Tanaka, Kichizo Kaga, Kanako Hatanaka, Yoshihiro Matsuno, Naoko Imai, Satoshi Hirano
Pages: 129-140
Published online on: 02 December 2016

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Article

The expression and function of epithelial membrane protein 1 in laryngeal carcinoma

Hong Li, Xiaowen Zhang, Xuejun Jiang, Xu Ji
Pages: 141-148
Published online on: 28 November 2016

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Article

Rb knockdown accelerates bladder cancer progression through E2F3 activation

Jiang-Ping Wang, Yong Jiao, Cheng-Yuan Wang, Zhi-Bin Xu, Bo Zhang
Pages: 149-160
Published online on: 06 December 2016

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Article

Metabolic reprogramming and AMPKα1 pathway activation by caulerpin in colorectal cancer cells

Hua Yu, Huiqin Zhang, Mingjun Dong, Zhou Wu, Zhonglei Shen, Yangyang Xie, Zhenfang Kong, Xiaoyu Dai, Binbin Xu
Pages: 161-172
Published online on: 06 December 2016

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Article

Aberrant TIMELESS expression is associated with poor clinical survival and lymph node metastasis in early-stage cervical carcinoma

Weijing Zhang, Weiling He, Yongjie Shi, Jing Zhao, Sailan Liu, Fengxiang Zhang, Jiarui Yang, Chuanmiao Xie, Yanna Zhang
Pages: 173-184
Published online on: 29 November 2016

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Article

NecroX-5 prevents breast cancer metastasis by AKT inhibition via reducing intracellular calcium levels

Jin-Hee Park, Hyoung Kyu Kim, Hana Jung, Ki Hyang Kim, Mi Seon Kang, Jun Hyuk Hong, Byeng Chul Yu, Sungjae Park, Su-Kil Seo, Il Whan Choi, Soon Ha Kim, Nari Kim, Jin Han, Sae Gwang Park
Pages: 185-192
Published online on: 05 December 2016

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Article

BMP signaling pathways affect differently migration and invasion of esophageal squamous cancer cells

Min Hu, Facai Cui, Fengzhen Liu, Jinlin Wang, Xiaoxia Wei, Yi Li
Pages: 193-202
Published online on: 12 December 2016

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Article

Dual inhibition using cabozantinib overcomes HGF/MET signaling mediated resistance to pan-VEGFR inhibition in orthotopic and metastatic neuroblastoma tumors

Estelle Daudigeos-Dubus, Ludivine Le Dret, Olivia Bawa, Paule Opolon, Albane Vievard, Irène Villa, Jacques Bosq, Gilles Vassal, Birgit Geoerger
Pages: 203-211
Published online on: 06 December 2016

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Article

Development of a therapeutic model of precancerous liver using crocin-coated magnetite nanoparticles

Rkia El-Kharrag, Amr Amin, Soleiman Hisaindee, Yaser Greish, Sherif M. Karam
Pages: 212-222
Published online on: 15 November 2016

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Article

Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents

Yang Chen, Huixian Zhang, Qiyang He
Pages: 223-231
Published online on: 23 November 2016

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Article

ETS-1: A potential target of glycolysis for metabolic therapy by regulating glucose metabolism in pancreatic cancer Expression of Concern in /10.3892/ijo.2025.5786

Xiu Zhang, Dan Wu, Mohanad Aldarouish, Xiaodong Yin, Chunyan Li, Cailian Wang
Pages: 232-240
Published online on: 16 November 2016

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Article

ESC-3 induces apoptosis of human ovarian carcinomas through Wnt/β-catenin and Notch signaling in vitro and in vivo

Qi-Rui Fu, Wei Song, Yi-Tao Deng, Hua-Liang Li, Xiao-Mei Mao, Chen-Lu Lin, Ya-Hui Zheng, Shu-Ming Chen, Qiong-Hua Chen, Qing-Xi Chen
Pages: 241-251
Published online on: 18 November 2016

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Article

Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression

Kaiyan Liu, Zhenjie Tang, Amin Huang, Ping Chen, Panpan Liu, Jing Yang, Wenhua Lu, Jianwei Liao, Yicheng Sun, Shijun Wen, Yumin Hu, Peng Huang
Pages: 252-262
Published online on: 18 November 2016

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Article

Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells

Liang Chen, Gang Wang, Yi Luo, Yongzhi Wang, Conghua Xie, Wei Jiang, Yu Xiao, Guofeng Qian, Xinghuan Wang
Pages: 263-271
Published online on: 05 December 2016

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Article

Upregulation of SMAD4 by MZF1 inhibits migration of human gastric cancer cells

Jin-Hee Lee, Sung-Su Kim, Hun Seok Lee, Sungyoul Hong, Nirmal Rajasekaran, Li-Hui Wang, Joon-Seok Choi, Young Kee Shin
Pages: 272-282
Published online on: 06 December 2016

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Article

2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression

Hai-Anh Nguyen, Soo-A Kim
Pages: 283-289
Published online on: 06 December 2016

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Article

Low-dose irradiation promotes proliferation of the human breast cancer MDA-MB-231 cells through accumulation of mutant P53

Si-Jie Li, Xin-Yue Liang, Hai-Jun Li, Wei Li, Lei Zhou, Hua-Qiu Chen, Song-Gen Ye, De-Hai Yu, Jiu-Wei Cui
Pages: 290-296
Published online on: 06 December 2016

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Article

Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway

Sunbin Ling, Lei Song, Ning Fan, Tingting Feng, Lu Liu, Xu Yang, Mingjie Wang, Yanling Li, Yu Tian, Feng Zhao, Ying Liu, Qihong Huang, Zhaoyuan Hou, Fei Xu, Lei Shi, Yan Li
Pages: 297-309
Published online on: 09 December 2016

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Article

Microtubule actin cross-linking factor 1, a novel target in glioblastoma

Najlaa Afghani, Toral Mehta, Jialiang Wang, Nan Tang, Omar Skalli, Quincy A. Quick
Pages: 310-316
Published online on: 09 December 2016

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Article

Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1 Corrigendum in /10.3892/ijo.2019.4670

Ahmed Abdelbaset‑Ismail, Daniel Pedziwiatr, Gabriela Schneider, Jacek Niklinski, Radoslaw Charkiewicz, Marcin Moniuszko, Magda Kucia, Mariusz Z. Ratajczak
Pages: 317-328
Published online on: 02 December 2016

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Article

CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells

Soo Young Lee, Kyung Ae Kim, Chang Hyun Kim, Young Jin Kim, Jae-Hyuk Lee, Hyeong Rok Kim
Pages: 329-336
Published online on: 09 December 2016

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Retraction Open Access

[Retracted] Epidermal growth factor-stimulated human cervical cancer cell growth is associated with EGFR and cyclin D1 activation, independent of COX-2 expression levels

Rajkishen Narayanan, Hye Na Kim, Narayanan K. Narayanan, Dominick Nargi, Bhagavathi Narayanan
Pages: 337-337
Published online on: 18 October 2016

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Correction Open Access

[Erratum] The cnidarian origin of the proto-oncogenes NF-κB/STAT and WNT-like oncogenic pathway drives the ctenophores (Review)

Joseph G. Sinkovics
Pages: 338-338
Published online on: 09 November 2016

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Correction Open Access

[Corrigendum] Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs

Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao
Pages: 339-339
Published online on: 06 October 2016

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Correction Open Access

[Corrigendum] Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma

Wei Yang, Xiaoyuan Wang, Wei Zheng, Kedong Li, Haofeng Liu, Yueming Sun
Pages: 340-340
Published online on: 24 October 2016

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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