Journal Articles

Open Access

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

Sara Häggblad Sahlberg, Anja C. Mortensen, Jakob Haglöf, Mikael K.R. Engskog, Torbjörn Arvidsson, Curt Pettersson, Bengt Glimelius, Bo Stenerlöw, Marika Nestor

Pages: 5-14 Published online on: 18 November 2016
Open Access

Inhibition of CDH17 gene expression via RNA interference reduces proliferation and apoptosis of human MKN28 gastric cancer cells

Rui Li, Hong‑Qiang Yang, Hai‑Lin Xi, Su Feng, Rui‑Hao Qin

Pages: 15-22 Published online on: 28 November 2016
Open Access

AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway

Masayuki Morishita, Teruya Kawamoto, Hitomi Hara, Yasuo Onishi, Takeshi Ueha, Masaya Minoda, Etsuko Katayama, Toshiyuki Takemori, Naomasa Fukase, Masahiro Kurosaka, Ryosuke Kuroda, Toshihiro Akisue

Pages: 23-30 Published online on: 21 November 2016
Open Access

Stathmin1 overexpression in hypopharyngeal squamous cell carcinoma: A new promoter in FaDu cell proliferation and migration

Yan Chen, Qicheng Zhang, Chuanjin Ding, Xiaobo Zhang, Xiaoxia Qiu, Zhenxin Zhang

Pages: 31-40 Published online on: 23 November 2016
Open Access

Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment

Mariko Hirai, Hiroko Kitahara, Yutaka Kobayashi, Koroku Kato, George Bou-Gharios, Hiroyuki Nakamura, Shuichi Kawashiri

Pages: 41-48 Published online on: 02 December 2016
Open Access

Long-term exposure of MCF-7 breast cancer cells to ethanol stimulates oncogenic features

Robert Gelfand, Dolores Vernet, Kevin W. Bruhn, Suren Sarkissyan, David Heber, Jaydutt V. Vadgama, Nestor F. Gonzalez-Cadavid

Pages: 49-65 Published online on: 09 December 2016
Open Access

Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers

Suni Lee, Hidenori Matsuzaki, Megumi Maeda, Shoko Yamamoto, Naoko Kumagai-Takei, Tamayo Hatayama, Miho Ikeda, Kei Yoshitome, Yasumitsu Nishimura, Takemi Otsuki

Pages: 66-74 Published online on: 22 November 2016

Enzalutamide inhibits proliferation of gemcitabine-resistant bladder cancer cells with increased androgen receptor expression

Koji Kameyama, Kengo Horie, Kosuke Mizutani, Taku Kato, Yasunori Fujita, Kyojiro Kawakami, Toshio Kojima, Tatsuhiko Miyazaki, Takashi Deguchi, Masafumi Ito

Pages: 75-84 Published online on: 24 November 2016

Pro-metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-Tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu

Pages: 85-92 Published online on: 08 December 2016

Baicalin attenuates DDP (cisplatin) resistance in lung cancer by downregulating MARK2 and p-Akt

Zhiwei Xu, Ju Mei, Yan Tan

Pages: 93-100 Published online on: 15 November 2016

Tetrandrine inhibits glioma stem-like cells by repressing β-catenin expression

Yong Zhang, Yu-Lin Wen, Ji-Wei Ma, Jie-Cheng Ye, Xiao Wang, Jian-Xian Huang, Chao-Yue Meng, Xiao-Ze Xu, Shao-Xiang Wang, Xue-Yun Zhong

Pages: 101-110 Published online on: 23 November 2016

Oridonin inhibition and miR‑200b‑3p/ZEB1 axis in human pancreatic cancer

Zhifang Gui, Feng Luo, Yayang Yang, Can Shen, Shuquan Li, Jian Xu

Pages: 111-120 Published online on: 18 November 2016

Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells

Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Hong Ji, Yiming Li, Xijuan Cui, Ya'an Kang

Pages: 121-128 Published online on: 23 November 2016

Differential detection of cytoplasmic Wilms tumor 1 expression by immunohistochemistry, western blotting and mRNA quantification

Takehiro Maki, Hiroaki Ikeda, Aki Kuroda, Noriaki Kyogoku, Yoshiyuki Yamamura, Yukiko Tabata, Takehiro Abiko, Takahiro Tsuchikawa, Yasuhiro Hida, Toshiaki Shichinohe, Eiichi Tanaka, Kichizo Kaga, Kanako Hatanaka, Yoshihiro Matsuno, Naoko Imai, Satoshi Hirano

Pages: 129-140 Published online on: 02 December 2016

The expression and function of epithelial membrane protein 1 in laryngeal carcinoma

Hong Li, Xiaowen Zhang, Xuejun Jiang, Xu Ji

Pages: 141-148 Published online on: 28 November 2016

Rb knockdown accelerates bladder cancer progression through E2F3 activation

Jiang-Ping Wang, Yong Jiao, Cheng-Yuan Wang, Zhi-Bin Xu, Bo Zhang

Pages: 149-160 Published online on: 06 December 2016

Metabolic reprogramming and AMPKα1 pathway activation by caulerpin in colorectal cancer cells

Hua Yu, Huiqin Zhang, Mingjun Dong, Zhou Wu, Zhonglei Shen, Yangyang Xie, Zhenfang Kong, Xiaoyu Dai, Binbin Xu

Pages: 161-172 Published online on: 06 December 2016

Aberrant TIMELESS expression is associated with poor clinical survival and lymph node metastasis in early-stage cervical carcinoma

Weijing Zhang, Weiling He, Yongjie Shi, Jing Zhao, Sailan Liu, Fengxiang Zhang, Jiarui Yang, Chuanmiao Xie, Yanna Zhang

Pages: 173-184 Published online on: 29 November 2016

NecroX-5 prevents breast cancer metastasis by AKT inhibition via reducing intracellular calcium levels

Jin-Hee Park, Hyoung Kyu Kim, Hana Jung, Ki Hyang Kim, Mi Seon Kang, Jun Hyuk Hong, Byeng Chul Yu, Sungjae Park, Su-Kil Seo, Il Whan Choi, Soon Ha Kim, Nari Kim, Jin Han, Sae Gwang Park

Pages: 185-192 Published online on: 05 December 2016

BMP signaling pathways affect differently migration and invasion of esophageal squamous cancer cells

Min Hu, Facai Cui, Fengzhen Liu, Jinlin Wang, Xiaoxia Wei, Yi Li

Pages: 193-202 Published online on: 12 December 2016

Dual inhibition using cabozantinib overcomes HGF/MET signaling mediated resistance to pan-VEGFR inhibition in orthotopic and metastatic neuroblastoma tumors

Estelle Daudigeos-Dubus, Ludivine Le Dret, Olivia Bawa, Paule Opolon, Albane Vievard, Irène Villa, Jacques Bosq, Gilles Vassal, Birgit Geoerger

Pages: 203-211 Published online on: 06 December 2016

Development of a therapeutic model of precancerous liver using crocin-coated magnetite nanoparticles

Rkia El-Kharrag, Amr Amin, Soleiman Hisaindee, Yaser Greish, Sherif M. Karam

Pages: 212-222 Published online on: 15 November 2016

Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents

Yang Chen, Huixian Zhang, Qiyang He

Pages: 223-231 Published online on: 23 November 2016

ETS-1: A potential target of glycolysis for metabolic therapy by regulating glucose metabolism in pancreatic cancer

Xiu Zhang, Dan Wu, Mohanad Aldarouish, Xiaodong Yin, Chunyan Li, Cailian Wang

Pages: 232-240 Published online on: 16 November 2016

ESC-3 induces apoptosis of human ovarian carcinomas through Wnt/β-catenin and Notch signaling in vitro and in vivo

Qi-Rui Fu, Wei Song, Yi-Tao Deng, Hua-Liang Li, Xiao-Mei Mao, Chen-Lu Lin, Ya-Hui Zheng, Shu-Ming Chen, Qiong-Hua Chen, Qing-Xi Chen

Pages: 241-251 Published online on: 18 November 2016

Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression

Kaiyan Liu, Zhenjie Tang, Amin Huang, Ping Chen, Panpan Liu, Jing Yang, Wenhua Lu, Jianwei Liao, Yicheng Sun, Shijun Wen, Yumin Hu, Peng Huang

Pages: 252-262 Published online on: 18 November 2016

Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells

Liang Chen, Gang Wang, Yi Luo, Yongzhi Wang, Conghua Xie, Wei Jiang, Yu Xiao, Guofeng Qian, Xinghuan Wang

Pages: 263-271 Published online on: 05 December 2016

Upregulation of SMAD4 by MZF1 inhibits migration of human gastric cancer cells

Jin-Hee Lee, Sung-Su Kim, Hun Seok Lee, Sungyoul Hong, Nirmal Rajasekaran, Li-Hui Wang, Joon-Seok Choi, Young Kee Shin

Pages: 272-282 Published online on: 06 December 2016

2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression

Hai-Anh Nguyen, Soo-A Kim

Pages: 283-289 Published online on: 06 December 2016

Low-dose irradiation promotes proliferation of the human breast cancer MDA-MB-231 cells through accumulation of mutant P53

Si-Jie Li, Xin-Yue Liang, Hai-Jun Li, Wei Li, Lei Zhou, Hua-Qiu Chen, Song-Gen Ye, De-Hai Yu, Jiu-Wei Cui

Pages: 290-296 Published online on: 06 December 2016

Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway

Sunbin Ling, Lei Song, Ning Fan, Tingting Feng, Lu Liu, Xu Yang, Mingjie Wang, Yanling Li, Yu Tian, Feng Zhao, Ying Liu, Qihong Huang, Zhaoyuan Hou, Fei Xu, Lei Shi, Yan Li

Pages: 297-309 Published online on: 09 December 2016

Microtubule actin cross-linking factor 1, a novel target in glioblastoma

Najlaa Afghani, Toral Mehta, Jialiang Wang, Nan Tang, Omar Skalli, Quincy A. Quick

Pages: 310-316 Published online on: 09 December 2016

Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1 Corrigendum in /10.3892/ijo.2019.4670

Ahmed Abdelbaset‑Ismail, Daniel Pedziwiatr, Gabriela Schneider, Jacek Niklinski, Radoslaw Charkiewicz, Marcin Moniuszko, Magda Kucia, Mariusz Z. Ratajczak

Pages: 317-328 Published online on: 02 December 2016

CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells

Soo Young Lee, Kyung Ae Kim, Chang Hyun Kim, Young Jin Kim, Jae-Hyuk Lee, Hyeong Rok Kim

Pages: 329-336 Published online on: 09 December 2016
Open Access

[Retracted] Epidermal growth factor-stimulated human cervical cancer cell growth is associated with EGFR and cyclin D1 activation, independent of COX-2 expression levels

Rajkishen Narayanan, Hye Na Kim, Narayanan K. Narayanan, Dominick Nargi, Bhagavathi Narayanan

Pages: 337-337 Published online on: 18 October 2016
Open Access

[Corrigendum] Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs

Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao

Pages: 339-339 Published online on: 06 October 2016
Open Access

[Corrigendum] Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma

Wei Yang, Xiaoyuan Wang, Wei Zheng, Kedong Li, Haofeng Liu, Yueming Sun

Pages: 340-340 Published online on: 24 October 2016
Journal Cover

Cover Legend PDF

January 2017
Volume 50 Issue 1

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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