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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2017 Volume 50 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells

Sara Häggblad Sahlberg, Anja C. Mortensen, Jakob Haglöf, Mikael K.R. Engskog, Torbjörn Arvidsson, Curt Pettersson, Bengt Glimelius, Bo Stenerlöw, Marika Nestor
Pages: 5-14
Published online on: 18 November 2016

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Article Open Access

Inhibition of CDH17 gene expression via RNA interference reduces proliferation and apoptosis of human MKN28 gastric cancer cells

Rui Li, Hong‑Qiang Yang, Hai‑Lin Xi, Su Feng, Rui‑Hao Qin
Pages: 15-22
Published online on: 28 November 2016

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Article Open Access

AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway

Masayuki Morishita, Teruya Kawamoto, Hitomi Hara, Yasuo Onishi, Takeshi Ueha, Masaya Minoda, Etsuko Katayama, Toshiyuki Takemori, Naomasa Fukase, Masahiro Kurosaka, Ryosuke Kuroda, Toshihiro Akisue
Pages: 23-30
Published online on: 21 November 2016

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Article Open Access

Stathmin1 overexpression in hypopharyngeal squamous cell carcinoma: A new promoter in FaDu cell proliferation and migration

Yan Chen, Qicheng Zhang, Chuanjin Ding, Xiaobo Zhang, Xiaoxia Qiu, Zhenxin Zhang
Pages: 31-40
Published online on: 23 November 2016

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Article Open Access

Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment

Mariko Hirai, Hiroko Kitahara, Yutaka Kobayashi, Koroku Kato, George Bou-Gharios, Hiroyuki Nakamura, Shuichi Kawashiri
Pages: 41-48
Published online on: 02 December 2016

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Article Open Access

Long-term exposure of MCF-7 breast cancer cells to ethanol stimulates oncogenic features

Robert Gelfand, Dolores Vernet, Kevin W. Bruhn, Suren Sarkissyan, David Heber, Jaydutt V. Vadgama, Nestor F. Gonzalez-Cadavid
Pages: 49-65
Published online on: 09 December 2016

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Article Open Access

Accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers

Suni Lee, Hidenori Matsuzaki, Megumi Maeda, Shoko Yamamoto, Naoko Kumagai-Takei, Tamayo Hatayama, Miho Ikeda, Kei Yoshitome, Yasumitsu Nishimura, Takemi Otsuki
Pages: 66-74
Published online on: 22 November 2016

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Article

Enzalutamide inhibits proliferation of gemcitabine-resistant bladder cancer cells with increased androgen receptor expression

Koji Kameyama, Kengo Horie, Kosuke Mizutani, Taku Kato, Yasunori Fujita, Kyojiro Kawakami, Toshio Kojima, Tatsuhiko Miyazaki, Takashi Deguchi, Masafumi Ito
Pages: 75-84
Published online on: 24 November 2016

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Article

Pro-metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-Tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Pages: 85-92
Published online on: 08 December 2016

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Article

Baicalin attenuates DDP (cisplatin) resistance in lung cancer by downregulating MARK2 and p-Akt

Zhiwei Xu, Ju Mei, Yan Tan
Pages: 93-100
Published online on: 15 November 2016

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Article

Tetrandrine inhibits glioma stem-like cells by repressing β-catenin expression

Yong Zhang, Yu-Lin Wen, Ji-Wei Ma, Jie-Cheng Ye, Xiao Wang, Jian-Xian Huang, Chao-Yue Meng, Xiao-Ze Xu, Shao-Xiang Wang, Xue-Yun Zhong
Pages: 101-110
Published online on: 23 November 2016

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Article

Oridonin inhibition and miR‑200b‑3p/ZEB1 axis in human pancreatic cancer

Zhifang Gui, Feng Luo, Yayang Yang, Can Shen, Shuquan Li, Jian Xu
Pages: 111-120
Published online on: 18 November 2016

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Article

Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells

Tao Shan, Shuo Chen, Xi Chen, Wan Run Lin, Wei Li, Jiancang Ma, Tao Wu, Hong Ji, Yiming Li, Xijuan Cui, Ya'an Kang
Pages: 121-128
Published online on: 23 November 2016

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Article

Differential detection of cytoplasmic Wilms tumor 1 expression by immunohistochemistry, western blotting and mRNA quantification

Takehiro Maki, Hiroaki Ikeda, Aki Kuroda, Noriaki Kyogoku, Yoshiyuki Yamamura, Yukiko Tabata, Takehiro Abiko, Takahiro Tsuchikawa, Yasuhiro Hida, Toshiaki Shichinohe, Eiichi Tanaka, Kichizo Kaga, Kanako Hatanaka, Yoshihiro Matsuno, Naoko Imai, Satoshi Hirano
Pages: 129-140
Published online on: 02 December 2016

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Article

The expression and function of epithelial membrane protein 1 in laryngeal carcinoma

Hong Li, Xiaowen Zhang, Xuejun Jiang, Xu Ji
Pages: 141-148
Published online on: 28 November 2016

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Article

Rb knockdown accelerates bladder cancer progression through E2F3 activation

Jiang-Ping Wang, Yong Jiao, Cheng-Yuan Wang, Zhi-Bin Xu, Bo Zhang
Pages: 149-160
Published online on: 06 December 2016

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Article

Metabolic reprogramming and AMPKα1 pathway activation by caulerpin in colorectal cancer cells

Hua Yu, Huiqin Zhang, Mingjun Dong, Zhou Wu, Zhonglei Shen, Yangyang Xie, Zhenfang Kong, Xiaoyu Dai, Binbin Xu
Pages: 161-172
Published online on: 06 December 2016

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Article

Aberrant TIMELESS expression is associated with poor clinical survival and lymph node metastasis in early-stage cervical carcinoma

Weijing Zhang, Weiling He, Yongjie Shi, Jing Zhao, Sailan Liu, Fengxiang Zhang, Jiarui Yang, Chuanmiao Xie, Yanna Zhang
Pages: 173-184
Published online on: 29 November 2016

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Article

NecroX-5 prevents breast cancer metastasis by AKT inhibition via reducing intracellular calcium levels

Jin-Hee Park, Hyoung Kyu Kim, Hana Jung, Ki Hyang Kim, Mi Seon Kang, Jun Hyuk Hong, Byeng Chul Yu, Sungjae Park, Su-Kil Seo, Il Whan Choi, Soon Ha Kim, Nari Kim, Jin Han, Sae Gwang Park
Pages: 185-192
Published online on: 05 December 2016

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Article

BMP signaling pathways affect differently migration and invasion of esophageal squamous cancer cells

Min Hu, Facai Cui, Fengzhen Liu, Jinlin Wang, Xiaoxia Wei, Yi Li
Pages: 193-202
Published online on: 12 December 2016

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Article

Dual inhibition using cabozantinib overcomes HGF/MET signaling mediated resistance to pan-VEGFR inhibition in orthotopic and metastatic neuroblastoma tumors

Estelle Daudigeos-Dubus, Ludivine Le Dret, Olivia Bawa, Paule Opolon, Albane Vievard, Irène Villa, Jacques Bosq, Gilles Vassal, Birgit Geoerger
Pages: 203-211
Published online on: 06 December 2016

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Article

Development of a therapeutic model of precancerous liver using crocin-coated magnetite nanoparticles

Rkia El-Kharrag, Amr Amin, Soleiman Hisaindee, Yaser Greish, Sherif M. Karam
Pages: 212-222
Published online on: 15 November 2016

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Article

Involvement of bleomycin hydrolase and poly(ADP-ribose) polymerase-1 in Ubc9-mediated resistance to chemotherapy agents

Yang Chen, Huixian Zhang, Qiyang He
Pages: 223-231
Published online on: 23 November 2016

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Article

ETS-1: A potential target of glycolysis for metabolic therapy by regulating glucose metabolism in pancreatic cancer Expression of Concern in /10.3892/ijo.2025.5786

Xiu Zhang, Dan Wu, Mohanad Aldarouish, Xiaodong Yin, Chunyan Li, Cailian Wang
Pages: 232-240
Published online on: 16 November 2016

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Article

ESC-3 induces apoptosis of human ovarian carcinomas through Wnt/β-catenin and Notch signaling in vitro and in vivo

Qi-Rui Fu, Wei Song, Yi-Tao Deng, Hua-Liang Li, Xiao-Mei Mao, Chen-Lu Lin, Ya-Hui Zheng, Shu-Ming Chen, Qiong-Hua Chen, Qing-Xi Chen
Pages: 241-251
Published online on: 18 November 2016

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Article

Glyceraldehyde-3-phosphate dehydrogenase promotes cancer growth and metastasis through upregulation of SNAIL expression

Kaiyan Liu, Zhenjie Tang, Amin Huang, Ping Chen, Panpan Liu, Jing Yang, Wenhua Lu, Jianwei Liao, Yicheng Sun, Shijun Wen, Yumin Hu, Peng Huang
Pages: 252-262
Published online on: 18 November 2016

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Article

Downregulation of LAPTM5 suppresses cell proliferation and viability inducing cell cycle arrest at G0/G1 phase of bladder cancer cells

Liang Chen, Gang Wang, Yi Luo, Yongzhi Wang, Conghua Xie, Wei Jiang, Yu Xiao, Guofeng Qian, Xinghuan Wang
Pages: 263-271
Published online on: 05 December 2016

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Article

Upregulation of SMAD4 by MZF1 inhibits migration of human gastric cancer cells

Jin-Hee Lee, Sung-Su Kim, Hun Seok Lee, Sungyoul Hong, Nirmal Rajasekaran, Li-Hui Wang, Joon-Seok Choi, Young Kee Shin
Pages: 272-282
Published online on: 06 December 2016

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Article

2'-Hydroxycinnamaldehyde induces apoptosis through HSF1-mediated BAG3 expression

Hai-Anh Nguyen, Soo-A Kim
Pages: 283-289
Published online on: 06 December 2016

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Article

Low-dose irradiation promotes proliferation of the human breast cancer MDA-MB-231 cells through accumulation of mutant P53

Si-Jie Li, Xin-Yue Liang, Hai-Jun Li, Wei Li, Lei Zhou, Hua-Qiu Chen, Song-Gen Ye, De-Hai Yu, Jiu-Wei Cui
Pages: 290-296
Published online on: 06 December 2016

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Article

Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway

Sunbin Ling, Lei Song, Ning Fan, Tingting Feng, Lu Liu, Xu Yang, Mingjie Wang, Yanling Li, Yu Tian, Feng Zhao, Ying Liu, Qihong Huang, Zhaoyuan Hou, Fei Xu, Lei Shi, Yan Li
Pages: 297-309
Published online on: 09 December 2016

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Article

Microtubule actin cross-linking factor 1, a novel target in glioblastoma

Najlaa Afghani, Toral Mehta, Jialiang Wang, Nan Tang, Omar Skalli, Quincy A. Quick
Pages: 310-316
Published online on: 09 December 2016

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Article

Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1 Corrigendum in /10.3892/ijo.2019.4670

Ahmed Abdelbaset‑Ismail, Daniel Pedziwiatr, Gabriela Schneider, Jacek Niklinski, Radoslaw Charkiewicz, Marcin Moniuszko, Magda Kucia, Mariusz Z. Ratajczak
Pages: 317-328
Published online on: 02 December 2016

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Article

CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells

Soo Young Lee, Kyung Ae Kim, Chang Hyun Kim, Young Jin Kim, Jae-Hyuk Lee, Hyeong Rok Kim
Pages: 329-336
Published online on: 09 December 2016

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Retraction Open Access

[Retracted] Epidermal growth factor-stimulated human cervical cancer cell growth is associated with EGFR and cyclin D1 activation, independent of COX-2 expression levels

Rajkishen Narayanan, Hye Na Kim, Narayanan K. Narayanan, Dominick Nargi, Bhagavathi Narayanan
Pages: 337-337
Published online on: 18 October 2016

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Correction Open Access

[Erratum] The cnidarian origin of the proto-oncogenes NF-κB/STAT and WNT-like oncogenic pathway drives the ctenophores (Review)

Joseph G. Sinkovics
Pages: 338-338
Published online on: 09 November 2016

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Correction Open Access

[Corrigendum] Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs

Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao
Pages: 339-339
Published online on: 06 October 2016

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Correction Open Access

[Corrigendum] Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma

Wei Yang, Xiaoyuan Wang, Wei Zheng, Kedong Li, Haofeng Liu, Yueming Sun
Pages: 340-340
Published online on: 24 October 2016

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Journal Cover
July-2026 Volume 69 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Emerging agents that target signaling pathways in cancer fibroblast cells (Review)

Yan Wan, Xiang-Qing Liu, Dong Liu, Ke-Di Li, Dan-Dan Zhang
Article Number: 87
Published online on: 03 June 2026

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Review Open Access

Metabolic remodeling by circular RNAs in gastric tumorigenesis: From mechanisms to biomarker discovery (Review)

Xinyi Liang, Tianlin Wang, Jiale Ma, Shuangmei Zhao, Wang Gao, Yan Yang, Xinyuan Zhang, Huizhen Li
Article Number: 86
Published online on: 03 June 2026

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Correction Open Access

[Corrigendum] Cell density‑dependent regulation of p73 in breast cancer cells

Chaitali Tophkhane, Shihe Yang, Zhizhuang Joe Zhao, Xiaohe Yang
Article Number: 85
Published online on: 25 May 2026

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Review Open Access

P2X7 receptor: An emerging therapeutic target in acute myeloid leukemia (Review)

Yunqing Liu, Hongfan Xue, Hanheng Mai, Tan Sang, Zonghong Li, Na Wang, Lili Feng
Article Number: 84
Published online on: 22 May 2026

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Expression of Concern Open Access

[Expression of Concern] Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects

D. Carlisi, B. Vassallo, M. Lauricella, S.  Emanuele, A. D'anneo, E. Di Leonardo, P. Di Fazio, R.  Vento, G.  Tesoriere
Article Number: 83
Published online on: 20 May 2026

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Article Open Access

Integrin beta 4 promotes colorectal cancer progression by upregulating Ezrin and activating the Wnt/β‑catenin signaling pathway

Jing Wang, Yi Si, Mingda Xuan, Shuangshuang Han, Kunyi Liu, Jiao Jiao, Xiaoyan Men, Hongfei Li, Jia Wang, Ting Liu, Weifang Yu
Article Number: 82
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Semaphorin 5A suppresses the proliferation and migration of lung adenocarcinoma cells

Pin-Hao Ko, Govinda Lenka, Yu-An Chen, Eric Y. Chuang, Mong-Hsun Tsai, Yuh-Pyng Sher, Liang-Chuan Lai
Article Number: 81
Published online on: 18 May 2026

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Review Open Access

snoRNAs and their derived sdRNAs: Emerging regulators, biomarkers, and therapeutic targets in human cancers (Review)

Jiahui Mao, Hao Lin, Feng Gu, Zhaoji Pan
Article Number: 80
Published online on: 15 May 2026

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Review Open Access

Deubiquitinating enzymes in cervical cancer: Molecular mechanisms and therapeutic implications (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 79
Published online on: 14 May 2026

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Article Open Access

BMP4 derived from human gastrointestinal carcinoma cells impairs myogenic differentiation: A possible in vitro mechanism of cancer‑induced cachexia

Kazuki Higure, Yoshihiko Kitajima, Naoya Kimura, Shota Ikeda, Shohei Matsufuji, Tomokazu Tanaka, Hirokazu Noshiro
Article Number: 78
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Radiation‑inducible silencing of uPA and uPAR in vitro and in vivo in meningioma

Venkateswara Rao Gogineni, Arun Kumar Nalla, Reshu Gupta, Bharathi Gorantla, Meena Gujrati, Dzung H. Dinh, Jasti S. Rao
Article Number: 77
Published online on: 11 May 2026

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Review Open Access

Circulating proteins as biomarkers of response to cancer immunotherapy (Review)

Celeste Pinard, Angeline Ginzac, Catherine Abrial, Xavier Durando, Nina Radosevic‑Robin
Article Number: 76
Published online on: 06 May 2026

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Correction Open Access

[Corrigendum] Tumor necrosis factor‑α triggers opposing signals in head and neck squamous cell carcinoma and induces apoptosis via mitochondrial‑ and non‑mitochondrial‑dependent pathways

Denis Selimovic, Renate   U. Wahl, Emmanuelle Ruiz, Rizwan Aslam, Thomas   W. Flanagan, Sofie-Yasmin Hassan, Simeon Santourlidis, Youssef Haikel, Paul Friedlander, Mosaad Megahed, Emad Kandil, Mohamed Hassan
Article Number: 75
Published online on: 27 April 2026

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Journal Cover
August-2026 Volume 69 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Downregulation of uPA/uPAR inhibits intermittent hypoxia‑induced epithelial‑mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells

Reshu Gupta, Chandramu Chetty, Praveen Bhoopathi, Sajani Lakka, Sanjeeva Mohanam, Asti S. Rao, Dzung H. Dinh
Article Number: 89
Published online on: 08 June 2026

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Review Open Access

Targeted therapy in BRAF‑mutant melanoma: Advances and challenges (Review)

Lu Zhang, Dongliang Shen, Jianguo Feng, Liling Tang
Article Number: 88
Published online on: 04 June 2026

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