1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
2
|
Ferlay J, Shin HR, Bray F, Forman D,
Mathers C and Parkin DM: Estimates of worldwide burden of cancer in
2008: GLOBOCAN 2008. Int J Cancer. 127:2893–2917. 2010. View Article : Google Scholar
|
3
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
4
|
Colombo M and Sangiovanni A:
Hepatocellular carcinoma. Recenti Prog Med. 107:386–394. 2016.In
Italian. PubMed/NCBI
|
5
|
Dondeti MF, El-Maadawy EA and Talaat RM:
Hepatitis-related hepatocellular carcinoma: Insights into cytokine
gene polymorphisms. World J Gastroenterol. 22:6800–6816. 2016.
View Article : Google Scholar : PubMed/NCBI
|
6
|
Sucandy I, Cheek S, Golas BJ, Tsung A,
Geller DA and Marsh JW: Longterm survival outcomes of patients
undergoing treatment with radiofrequency ablation for
hepatocellular carcinoma and metastatic colorectal cancer liver
tumors. HPB Oxf. 18:756–763. 2016. View Article : Google Scholar
|
7
|
Liu H, Liu JY, Wu X and Zhang JT:
Biochemistry, molecular biology, and pharmacology of fatty acid
synthase, an emerging therapeutic target and diagnosis/prognosis
marker. Int J Biochem Mol Biol. 1:69–89. 2010.PubMed/NCBI
|
8
|
Cerne D, Zitnik IP and Sok M: Increased
fatty acid synthase activity in non-small cell lung cancer tissue
is a weaker predictor of shorter patient survival than increased
lipoprotein lipase activity. Arch Med Res. 41:405–409. 2010.
View Article : Google Scholar : PubMed/NCBI
|
9
|
Daker M, Bhuvanendran S, Ahmad M, Takada K
and Khoo AS: Deregulation of lipid metabolism pathway genes in
nasopharyngeal carcinoma cells. Mol Med Rep. 7:731–741.
2013.PubMed/NCBI
|
10
|
Grunt TW, Wagner R, Grusch M, Berger W,
Singer CF, Marian B, Zielinski CC and Lupu R: Interaction between
fatty acid synthase- and ErbB-systems in ovarian cancer cells.
Biochem Biophys Res Commun. 385:454–459. 2009. View Article : Google Scholar : PubMed/NCBI
|
11
|
Zhou Y, Niu C, Li Y, Gao B, Zheng J, Guo X
and Ma W: Fatty acid synthase expression and esophageal cancer. Mol
Biol Rep. 39:9733–9739. 2012. View Article : Google Scholar : PubMed/NCBI
|
12
|
Hao Q, Li T, Zhang X, Gao P, Qiao P, Li S
and Geng Z: Expression and roles of fatty acid synthase in
hepatocellular carcinoma. Oncol Rep. 32:2471–2476. 2014.PubMed/NCBI
|
13
|
Long XH, Mao JH, Peng AF, Zhou Y, Huang SH
and Liu ZL: Tumor suppressive microRNA-424 inhibits osteosarcoma
cell migration and invasion via targeting fatty acid synthase. Exp
Ther Med. 5:1048–1052. 2013.PubMed/NCBI
|
14
|
Shi T, Dong Y, Li J, Gao P, Fu D and Ma D:
High-throughput screening identifies CHMP4A associated with
hypoxia-inducible factor 1. Life Sci. 87:604–608. 2010. View Article : Google Scholar : PubMed/NCBI
|
15
|
Gan CS, Chong PK, Pham TK and Wright PC:
Technical, experimental, and biological variations in isobaric tags
for relative and absolute quantitation (iTRAQ). J Proteome Res.
6:821–827. 2007. View Article : Google Scholar : PubMed/NCBI
|
16
|
Firth SM and Baxter RC: Cellular actions
of the insulin-like growth factor binding proteins. Endocr Rev.
23:824–854. 2002. View Article : Google Scholar : PubMed/NCBI
|
17
|
Frede S, Berchner-Pfannschmidt U and
Fandrey J: Regulation of hypoxia-inducible factors during
inflammation. Methods Enzymol. 435:405–419. 2007.PubMed/NCBI
|
18
|
Richard DE, Berra E, Gothié E, Roux D and
Pouysségur J: p42/p44 mitogen-activated protein kinases
phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and
enhance the transcriptional activity of HIF-1. J Biol Chem.
274:32631–32637. 1999. View Article : Google Scholar : PubMed/NCBI
|
19
|
Qiao M, Sheng S and Pardee AB: Metastasis
and AKT activation. Cell Cycle. 7:2991–2996. 2008. View Article : Google Scholar : PubMed/NCBI
|
20
|
Belghiti J and Fuks D: Liver resection and
transplantation in hepatocellular carcinoma. Liver Cancer. 1:71–82.
2012. View Article : Google Scholar
|
21
|
Schwartz M, Roayaie S and Llovet J: How
should patients with hepatocellular carcinoma recurrence after
liver transplantation be treated? J Hepatol. 43:584–589. 2005.
View Article : Google Scholar : PubMed/NCBI
|
22
|
Cairns RA, Harris I, McCracken S and Mak
TW: Cancer cell metabolism. Cold Spring Harb Symp Quant Biol.
76:299–311. 2011. View Article : Google Scholar : PubMed/NCBI
|
23
|
Zhang H, Li H, Yang Y, Li S, Ren H, Zhang
D and Hu H: Differential regulation of host genes including hepatic
fatty acid synthase in HBV-transgenic mice. J Proteome Res.
12:2967–2979. 2013. View Article : Google Scholar : PubMed/NCBI
|
24
|
Lee PD, Giudice LC, Conover CA and Powell
DR: Insulin-like growth factor binding protein-1: Recent findings
and new directions. Proc Soc Exp Biol Med. 216:319–357. 1997.
View Article : Google Scholar : PubMed/NCBI
|
25
|
Jones JI, Gockerman A, Busby WH Jr, Wright
G and Clemmons DR: Insulin-like growth factor binding protein 1
stimulates cell migration and binds to the alpha 5 beta 1 integrin
by means of its Arg-Gly-Asp sequence. Proc Natl Acad Sci USA.
90:10553–10557. 1993. View Article : Google Scholar : PubMed/NCBI
|
26
|
Semenza GL: Oxygen sensing, homeostasis,
and disease. N Engl J Med. 365:537–547. 2011. View Article : Google Scholar : PubMed/NCBI
|
27
|
Sugawara J, Tazuke SI, Suen LF, Powell DR,
Kaper F, Giaccia AJ and Giudice LC: Regulation of insulin-like
growth factor-binding protein 1 by hypoxia and 3′,5′-cyclic
adenosine monophosphate is additive in HepG2 cells. J Clin
Endocrinol Metab. 85:3821–3827. 2000.PubMed/NCBI
|
28
|
Tuomisto TT, Rissanen TT, Vajanto I,
Korkeela A, Rutanen J and Ylä-Herttuala S: HIF-VEGF-VEGFR-2,
TNF-alpha and IGF pathways are upregulated in critical human
skeletal muscle ischemia as studied with DNA array.
Atherosclerosis. 174:111–120. 2004. View Article : Google Scholar : PubMed/NCBI
|
29
|
Bertout JA, Patel SA and Simon MC: The
impact of O2 availability on human cancer. Nat Rev Cancer.
8:967–975. 2008. View
Article : Google Scholar : PubMed/NCBI
|
30
|
Menendez JA, Vellon L, Oza BP and Lupu R:
Does endogenous fatty acid metabolism allow cancer cells to sense
hypoxia and mediate hypoxic vasodilatation? Characterization of a
novel molecular connection between fatty acid synthase (FAS) and
hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of
vascular endothelial growth factor (VEGF) in cancer cells
overexpressing her-2/neu oncogene. J Cell Biochem. 94:857–863.
2005. View Article : Google Scholar : PubMed/NCBI
|
31
|
Seguin F, Carvalho MA, Bastos DC, Agostini
M, Zecchin KG, Alvarez-Flores MP, Chudzinski-Tavassi AM, Coletta RD
and Graner E: The fatty acid synthase inhibitor orlistat reduces
experimental metastases and angiogenesis in B16-F10 melanomas. Br J
Cancer. 107:977–987. 2012. View Article : Google Scholar : PubMed/NCBI
|
32
|
Zhou Y, Jin G, Mi R, Zhang J, Zhang J, Xu
H, Cheng S, Zhang Y, Song W and Liu F: Inhibition of fatty acid
synthase suppresses neovascularization via regulating the
expression of VEGF-A in glioma. J Cancer Res Clin Oncol.
142:2447–2459. 2016. View Article : Google Scholar : PubMed/NCBI
|
33
|
Lu GY, Huang SM, Liu ST, Liu PY, Chou WY
and Lin WS: Caffeine induces tumor cytotoxicity via the regulation
of alternative splicing in subsets of cancer-associated genes. Int
J Biochem Cell Biol. 47:83–92. 2014. View Article : Google Scholar
|
34
|
Chang L, Wu P, Senthilkumar R, Tian X, Liu
H, Shen X, Tao Z and Huang P: Loss of fatty acid synthase
suppresses the malignant phenotype of colorectal cancer cells by
down-regulating energy metabolism and mTOR signaling pathway. J
Cancer Res Clin Oncol. 142:59–72. 2016. View Article : Google Scholar
|
35
|
Liu ZL, Mao JH, Peng AF, Yin QS, Zhou Y,
Long XH and Huang SH: Inhibition of fatty acid synthase suppresses
osteosarcoma cell invasion and migration via downregulation of the
PI3K/Akt signaling pathway in vitro. Mol Med Rep. 7:608–612.
2013.
|
36
|
Mao JH, Zhou RP, Peng AF, Liu ZL, Huang
SH, Long XH and Shu Y: microRNA-195 suppresses osteosarcoma cell
invasion and migration in vitro by targeting FASN. Oncol Lett.
4:1125–1129. 2012.PubMed/NCBI
|
37
|
Singh R, Yadav V, Kumar S and Saini N:
MicroRNA-195 inhibits proliferation, invasion and metastasis in
breast cancer cells by targeting FASN, HMGCR, ACACA and CYP27B1.
Sci Rep. 5:174542015. View Article : Google Scholar : PubMed/NCBI
|
38
|
Wang TF, Wang H, Peng AF, Luo QF, Liu ZL,
Zhou RP, Gao S, Zhou Y and Chen WZ: Inhibition of fatty acid
synthase suppresses U-2 OS cell invasion and migration via
down-regulating the activity of HER2/PI3K/AKT signaling pathway in
vitro. Biochem Biophys Res Commun. 440:229–234. 2013. View Article : Google Scholar : PubMed/NCBI
|
39
|
Yu B, Miao ZH, Jiang Y, Li MH, Yang N, Li
T and Ding J: c-Jun protects hypoxia-inducible factor-1alpha from
degradation via its oxygen-dependent degradation domain in a
nontranscriptional manner. Cancer Res. 69:7704–7712. 2009.
View Article : Google Scholar : PubMed/NCBI
|
40
|
Cai Q, Wang Z, Wang S, Weng M, Zhou D, Li
C, Wang J, Chen E and Quan Z: Long non-coding RNA LINC00152
promotes gallbladder cancer metastasis and epithelial-mesenchymal
transition by regulating HIF-1alpha via miR-138. Open Biol.
7:1602472017. View Article : Google Scholar
|
41
|
Maroni P, Matteucci E, Bendinelli P and
Desiderio MA: Functions and epigenetic regulation of Wwox in bone
metastasis from breast carcinoma: Comparison with primary tumors.
Int J Mol Sci. 18:182017. View Article : Google Scholar
|
42
|
Sun LL, Song Z, Li WZ and Tang SY: Hypoxia
facilitates epithelial-mesenchymal transition-mediated rectal
cancer progress. Genet Mol Res. 15:152016. View Article : Google Scholar
|
43
|
Yan X, Jiao SC, Zhang GQ, Guan Y and Wang
JL: Tumor-associated immune factors are associated with recurrence
and metastasis in non-small cell lung cancer. Cancer Gene Ther.
2017. View Article : Google Scholar : PubMed/NCBI
|