|
1
|
Ramachandra M, Atencio I, Rahman A,
Vaillancourt M, Zou A, Avanzini J, Wills K, Bookstein R and Shabram
P: Restoration of transforming growth factor beta signaling by
functional expression of smad4 induces anoikis. Cancer Res.
62:6045–6051. 2002.PubMed/NCBI
|
|
2
|
Lefter LP, Furukawa T, Sunamura M, Duda
DG, Takeda K, Kotobuki N, Oshimura M, Matsuno S and Horii A:
Suppression of the tumorigenic phenotype by chromosome 18 transfer
into pancreatic cancer cell lines. Genes Chromosomes Cancer.
34:234–242. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Yatsuoka T, Sunamura M, Furukawa T,
Fukushige S, Yokoyama T, Inoue H, Shibuya K, Takeda K, Matsuno S
and Horii A: Association of poor prognosis with loss of 12q, 17p,
and 18q, and concordant loss of 6q/17p and 12q/18q in human
pancreatic ductal adenocarcinoma. Am J Gastroenterol. 95:2080–2085.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Schwarte-Waldhoff I and Schmiegel W: Smad4
transcriptional pathways and angiogenesis. Int J Gastrointest
Cancer. 31:47–59. 2002. View Article : Google Scholar
|
|
5
|
Radisky DC and Bissell MJ: Cancer. Respect
thy neighbor. Science. 303:775–777. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Berg JN, Gallione CJ, Stenzel TT, Johnson
DW, Allen WP, Schwartz CE, Jackson CE, Porteous ME and Marchuk DA:
The activin receptor-like kinase 1 gene: Genomic structure and
mutations in hereditary hemorrhagic telangiectasia type 2. Am J Hum
Genet. 61:60–67. 1997. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Gallione CJ, Repetto GM, Legius E, Rustgi
AK, Schelley SL, Tejpar S, Mitchell G, Drouin E, Westermann CJ and
Marchuk DA: A combined syndrome of juvenile polyposis and
hereditary haemorrhagic telangiectasia associated with mutations in
MADH4 (SMAD4). Lancet. 363:852–859. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
McAllister KA, Grogg KM, Johnson DW,
Gallione CJ, Baldwin MA, Jackson CE, Helmbold EA, Markel DS,
McKinnon WC, Murrell J, et al: Endoglin, a TGF-beta binding protein
of endothelial cells, is the gene for hereditary haemorrhagic
telangiectasia type 1. Nat Genet. 8:345–351. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Morgan T, McDonald J, Anderson C, Ismail
M, Miller F, Mao R, Madan A, Barnes P, Hudgins L and Manning M:
Intracranial hemorrhage in infants and children with hereditary
hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome).
Pediatrics. 109:E122002. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Liu S, Yu M, He Y, Xiao L, Wang F, Song C,
Sun S, Ling C and Xu Z: Melittin prevents liver cancer cell
metastasis through inhibition of the Rac1-dependent pathway.
Hepatology. 47:1964–1973. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Huang X, Bai X, Cao Y, Wu J, Huang M, Tang
D, Tao S, Zhu T, Liu Y, Yang Y, et al: Lymphoma endothelium
preferentially expresses Tim-3 and facilitates the progression of
lymphoma by mediating immune evasion. J Exp Med. 207:505–520. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lan Y, Liu B, Yao H, Li F, Weng T, Yang G,
Li W, Cheng X, Mao N and Yang X: Essential role of endothelial
Smad4 in vascular remodeling and integrity. Mol Cell Biol.
27:7683–7692. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Nakagawa S, Deli MA, Nakao S, Honda M,
Hayashi K, Nakaoke R, Kataoka Y and Niwa M: Pericytes from brain
microvessels strengthen the barrier integrity in primary cultures
of rat brain endothelial cells. Cell Mol Neurobiol. 27:687–694.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Darland DC and D'Amore PA: TGF beta is
required for the formation of capillary-like structures in
three-dimensional cocultures of 10T1/2 and endothelial cells.
Angiogenesis. 4:11–20. 2001. View Article : Google Scholar
|
|
15
|
Anderberg C, Cunha SI, Zhai Z, Cortez E,
Pardali E, Johnson JR, Franco M, Páez-Ribes M, Cordiner R, Fuxe J,
et al: Deficiency for endoglin in tumor vasculature weakens the
endothelial barrier to metastatic dissemination. J Exp Med.
210:563–579. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Daneman R, Zhou L, Kebede AA and Barres
BA: Pericytes are required for blood-brain barrier integrity during
embryogenesis. Nature. 468:562–566. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Lindahl P, Johansson BR, Levéen P and
Betsholtz C: Pericyte loss and microaneurysm formation in
PDGF-B-deficient mice. Science. 277:242–245. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Dickson MC, Martin JS, Cousins FM,
Kulkarni AB, Karlsson S and Akhurst RJ: Defective haematopoiesis
and vasculogenesis in transforming growth factor-beta 1 knock out
mice. Development. 121:1845–1854. 1995.PubMed/NCBI
|
|
19
|
Larsson J, Goumans MJ, Sjöstrand LJ, van
Rooijen MA, Ward D, Levéen P, Xu X, ten Dijke P, Mummery CL and
Karlsson S: Abnormal angiogenesis but intact hematopoietic
potential in TGF-beta type I receptor-deficient mice. EMBO J.
20:1663–1673. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Li DY, Sorensen LK, Brooke BS, Urness LD,
Davis EC, Taylor DG, Boak BB and Wendel DP: Defective angiogenesis
in mice lacking endoglin. Science. 284:1534–1537. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Oh SP, Seki T, Goss KA, Imamura T, Yi Y,
Donahoe PK, Li L, Miyazono K, ten Dijke P, Kim S, et al: Activin
receptor-like kinase 1 modulates transforming growth factor-beta 1
signaling in the regulation of angiogenesis. Proc Natl Acad Sci
USA. 97:2626–2631. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yang X, Castilla LH, Xu X, Li C, Gotay J,
Weinstein M, Liu PP and Deng CX: Angiogenesis defects and
mesenchymal apoptosis in mice lacking SMAD5. Development.
126:1571–1580. 1999.PubMed/NCBI
|
|
23
|
Kumar P, Shen Q, Pivetti CD, Lee ES, Wu MH
and Yuan SY: Molecular mechanisms of endothelial hyperpermeability:
Implications in inflammation. Expert Rev Mol Med. 11:e192009.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Nwariaku FE, Liu Z, Zhu X, Turnage RH,
Sarosi GA and Terada LS: Tyrosine phosphorylation of vascular
endothelial cadherin and the regulation of microvascular
permeability. Surgery. 132:180–185. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Tinsley JH, Ustinova EE, Xu W and Yuan SY:
Src-dependent, neutrophil-mediated vascular hyperpermeability and
beta-catenin modification. Am J Physiol Cell Physiol.
283:C1745–C1751. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Paul R, Zhang ZG, Eliceiri BP, Jiang Q,
Boccia AD, Zhang RL, Chopp M and Cheresh DA: Src deficiency or
blockade of Src activity in mice provides cerebral protection
following stroke. Nat Med. 7:222–227. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Weis S, Shintani S, Weber A, Kirchmair R,
Wood M, Cravens A, McSharry H, Iwakura A, Yoon YS, Himes N, et al:
Src blockade stabilizes a Flk/cadherin complex, reducing edema and
tissue injury following myocardial infarction. J Clin Invest.
113:885–894. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Eliceiri BP, Paul R, Schwartzberg PL, Hood
JD, Leng J and Cheresh DA: Selective requirement for Src kinases
during VEGF-induced angiogenesis and vascular permeability. Mol
Cell. 4:915–924. 1999. View Article : Google Scholar
|
|
29
|
Mehta D and Malik AB: Signaling mechanisms
regulating endothelial permeability. Physiol Rev. 286:279–367.
2006. View Article : Google Scholar
|
|
30
|
Gong P, Angelini DJ, Yang S, Xia G, Cross
AS, Mann D, Bannerman DD, Vogel SN and Goldblum SE: TLR4 signaling
is coupled to SRC family kinase activation, tyrosine
phosphorylation of zonula adherens proteins, and opening of the
paracellular pathway in human lung microvascular endothelia. J Biol
Chem. 283:13437–13449. 2008. View Article : Google Scholar : PubMed/NCBI
|
