|
1
|
Savolainen K, Bhaumik P, Schmitz W, Kotti
TJ, Conzelmann E, Wierenga RK and Hiltunen JK: Alpha-methylacyl-CoA
racemase from Mycobacterium tuberculosis. Mutational and structural
characterization of the active site and the fold. J Biol Chem.
280:12611–12620. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bhaumik P, Schmitz W, Hassinen A, Hiltunen
JK, Conzelmann E and Wierenga RK: The catalysis of the 1,1-proton
transfer by alpha-methyl-acyl-CoA racemase is coupled to a movement
of the fatty acyl moiety over a hydrophobic, methionine-rich
surface. J Mol Biol. 367:1145–1161. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Lloyd MD, Darley DJ, Wierzbicki AS and
Threadgill MD: Alpha-methylacyl-CoA racemase--an 'obscure'
metabolic enzyme takes centre stage. FEBS J. 275:1089–1102. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Lloyd MD, Yevglevskis M, Lee GL, Wood PJ,
Threadgill MD and Woodman TJ: α-Methylacyl-CoA racemase (AMACR):
Metabolic enzyme, drug metabolizer and cancer marker P504S. Prog
Lipid Res. 52:220–230. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Baron A, Migita T, Tang D and Loda M:
Fatty acid synthase: A metabolic oncogene in prostate cancer? J
Cell Biochem. 91:47–53. 2004. View Article : Google Scholar
|
|
6
|
Jiang Z, Fanger GR, Woda BA, Banner BF,
Algate P, Dresser K, Xu J and Chu PG: Expression of
alpha-methylacyl-CoA racemase (P504s) in various malignant
neoplasms and normal tissues: Astudy of 761 cases. Hum Pathol.
34:792–796. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Rohrmann S, Platz EA, Kavanaugh CJ, Thuita
L, Hoffman SC and Helzlsouer KJ: Meat and dairy consumption and
subsequent risk of prostate cancer in a US cohort study. Cancer
Causes Control. 18:41–50. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Carnell AJ, Hale I, Denis S, Wanders RJ,
Isaacs WB, Wilson BA and Ferdinandusse S: Design, synthesis, and in
vitro testing of alpha-methylacyl-CoA racemase inhibitors. J Med
Chem. 50:2700–2707. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Carnell AJ, Kirk R, Smith M, McKenna S,
Lian LY and Gibson R: Inhibition of human α-methylacyl CoA racemase
(AMACR): A target for prostate cancer. ChemMedChem. 8:1643–1647.
2013.PubMed/NCBI
|
|
10
|
Schmitz W, Fingerhut R and Conzelmann E:
Purification and properties of an alpha-methylacyl-CoA racemase
from rat liver. Eur J Biochem. 222:313–323. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Xu J, Stolk JA, Zhang X, Silva SJ,
Houghton RL, Matsumura M, Vedvick TS, Leslie KB, Badaro R and Reed
SG: Identification of differentially expressed genes in human
prostate cancer using subtraction and microarray. Cancer Res.
60:1677–1682. 2000.PubMed/NCBI
|
|
12
|
Jiang Z, Woda BA, Rock KL, Xu Y, Savas L,
Khan A, Pihan G, Cai F, Babcook JS, Rathanaswami P, et al: P504S: A
new molecular marker for the detection of prostate carcinoma. Am J
Surg Pathol. 25:1397–1404. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Luo J, Zha S, Gage WR, Dunn TA, Hicks JL,
Bennett CJ, Ewing CM, Platz EA, Ferdinandusse S, Wanders RJ, et al:
Alpha-methylacyl-CoA racemase: A new molecular marker for prostate
cancer. Cancer Res. 62:2220–2226. 2002.PubMed/NCBI
|
|
14
|
Zhou M, Chinnaiyan AM, Kleer CG, Lucas PC
and Rubin MA: Alpha-Methylacyl-CoA racemase: A novel tumor marker
over-expressed in several human cancers and their precursor
lesions. Am J Surg Pathol. 26:926–931. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Rubin MA, Zhou M, Dhanasekaran SM,
Varambally S, Barrette TR, Sanda MG, Pienta KJ, Ghosh D and
Chinnaiyan AM: alpha-Methylacyl coenzyme A racemase as a tissue
biomarker for prostate cancer. JAMA. 287:1662–1670. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Jiang Z, Woda BA, Wu CL and Yang XJ:
Discovery and clinical application of a novel prostate cancer
marker: Alpha-methylacyl CoA racemase (P504S). Am J Clin Pathol.
122:275–289. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Adley BP and Yang XJ: Application of
alpha-methylacyl coenzyme A racemase immunohistochemistry in the
diagnosis of prostate cancer: A review. Anal Quant Cytol Histol.
28:1–13. 2006.PubMed/NCBI
|
|
18
|
Kapoor S: AMACR: An emerging diagnostic
and prognostic tool in systemic malignancies. Int Urol Nephrol.
45:439–440. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Chen W, Wu W, Zhao J, Yu C, Liu W, Jiang A
and Zhang J: Molecular cloning and preliminary analysis of the
human alpha-methylacyl-CoA racemase promoter. Mol Biol Rep.
36:423–430. 2009. View Article : Google Scholar
|
|
20
|
Sekine S, Ogawa R, Ojima H and Kanai Y:
Overexpression of α-methylacyl-CoA racemase is associated with
CTNNB1 mutations in hepatocellular carcinomas. Histopathology.
58:712–719. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Nusse R and Clevers H: Wnt/β-catenin
signaling, disease, and emerging therapeutic modalities. Cell.
169:985–999. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Bosetti C, Bertuccio P, Malvezzi M, Levi
F, Chatenoud L, Negri E and La Vecchia C: Cancer mortality in
Europe, 2005–2009, and an overview of trends since 1980. Ann Oncol.
24:2657–2671. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Honma I, Torigoe T, Hirohashi Y, Kitamura
H, Sato E, Masumori N, Tamura Y, Tsukamoto T and Sato N and Sato N:
Aberrant expression and potency as a cancer immunotherapy target of
alpha-methylacyl-coenzyme A racemase in prostate cancer. J Transl
Med. 7:1032009. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lin PY, Cheng KL, McGuffin-Cawley JD,
Shieu FS, Samia AC, Gupta S, Cooney M, Thompson CL and Liu CC:
Detection of alpha-methylacyl-CoA racemase (AMACR), a biomarker of
prostate cancer, in patient blood samples using a nanoparticle
electrochemical biosensor. Biosensors (Basel). 2:377–387. 2012.
View Article : Google Scholar
|
|
25
|
Nickens KP, Ali A, Scoggin T, Tan SH,
Ravindranath L, McLeod DG, Dobi A, Tacha D, Sesterhenn IA,
Srivastava S, et al: Prostate cancer marker panel with single cell
sensitivity in urine. Prostate. 75:969–975. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mayrose I, Penn O, Erez E, Rubinstein ND,
Shlomi T, Freund NT, Bublil EM, Ruppin E, Sharan R, Gershoni JM, et
al: Pepitope: Epitope mapping from affinity-selected peptides.
Bioinformatics. 23:3244–3246. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Mayrose I, Shlomi T, Rubinstein ND,
Gershoni JM, Ruppin E, Sharan R and Pupko T: Epitope mapping using
combinatorial phage-display libraries: A graph-based algorithm.
Nucleic Acids Res. 35:69–78. 2007. View Article : Google Scholar :
|
|
28
|
Liu HM, Newbrough SE, Bhatia SK, Dahle CE,
Krieg AM and Weiner GJ: Immunostimulatory CpG oligodeoxynucleotides
enhance the immune response to vaccine strategies involving
granulocyte-macrophage colony-stimulating factor. Blood.
92:3730–3736. 1998.PubMed/NCBI
|
|
29
|
Popov B and Kaczmarek L: Antibody raised
to the short sequence from the zinc-finger domain of the EGR-1
recognizes 102 KD protein in mouse fibroblasts. Biochem Mol Biol
Int. 32:39–47. 1994.PubMed/NCBI
|
|
30
|
Negi SS and Braun W: Automated detection
of conformational epitopes using phage display Peptide sequences.
Bioinform Biol Insights. 3:71–81. 2009. View Article : Google Scholar
|
|
31
|
Petrov NS and Popov BV: Study of Wnt2
secreted by A-549 cells in paracrine activation of β-catenin in
co-cultured mesenchymal stem cells. Biochemistry (Mosc).
79:524–530. 2014. View Article : Google Scholar
|
|
32
|
Weill CO, Biri S and Erbacher P: Cationic
lipid-mediated intracellular delivery of antibodies into live
cells. Biotechniques. 44:Pvii–Pxi. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Amery L, Fransen M, De Nys K, Mannaerts GP
and Van Veldhoven PP: Mitochondrial and peroxisomal targeting of
2-methylacyl-CoA racemase in humans. J Lipid Res. 41:1752–1759.
2000.PubMed/NCBI
|
|
34
|
Pedersen JI, Veggan T and Björkhem I:
Substrate stereospecificity in oxidation of (25S)-3 alpha, 7 alpha,
12 alpha-trihydroxy-5 beta-cholestanoyl-CoA by peroxisomal
trihydroxy-5 beta-cholestanoyl-CoA oxidase. Biochem Biophys Res
Commun. 224:37–42. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Hiltunen JK and Qin Y: beta-oxidation -
strategies for the metabolism of a wide variety of acyl-CoA esters.
Biochim Biophys Acta. 1484:117–128. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Russell DW: The enzymes, regulation, and
genetics of bile acid synthesis. Annu Rev Biochem. 72:137–174.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kotti TJ, Savolainen K, Helander HM, Yagi
A, Novikov DK, Kalkkinen N, Conzelmann E, Hiltunen JK and Schmitz
W: In mouse alpha -methylacyl-CoA racemase, the same gene product
is simultaneously located in mitochondria and peroxisomes. J Biol
Chem. 275:20887–20895. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ouyang B, Leung YK, Wang V, Chung E, Levin
L, Bracken B, Cheng L and Ho SM: α-Methylacyl-CoA racemase spliced
variants and their expression in normal and malignant prostate
tissues. Urology. 77:249.e1–249.e7. 2011. View Article : Google Scholar
|
|
39
|
White WB, Coleman JP and Hylemon PB:
Molecular cloning of a gene encoding a 45,000-dalton polypeptide
associated with bile acid 7-dehydroxylation in Eubacterium sp
strain VPI 12708. J Bacteriol. 170:611–616. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Sharma S, Bhaumik P, Schmitz W, Venkatesan
R, Hiltunen JK, Conzelmann E, Juffer AH and Wierenga RK: The
enolization chemistry of a thioester-dependent racemase: The 1.4 Å
crystal structure of a reaction intermediate complex characterized
by detailed QM/MM calculations. J Phys Chem B. 116:3619–3629. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Li X, Zheng QC and Zhang HX: Quantum
chemical modeling of 1,1-proton transfer reaction catalyzed by a
cofactor-independent α-methylacyl-CoA racemase. Int J Quantum Chem.
112:619–624. 2012. View Article : Google Scholar
|
