|
1
|
Berner K, Johannesen TB and Bruland OS:
Clinical epidemiology of low-grade and dedifferentiated
osteosarcoma in Norway during 1975 and 2009. Sarcoma.
2015:9176792015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Longhi A, Errani C, De Paolis M, Mercuri M
and Bacci G: Primary bone osteosarcoma in the pediatric age: State
of the art. Cancer Treat Rev. 32:423–436. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Anderson ME: Update on survival in
osteosarcoma. Orthop Clin North Am. 47:283–292. 2016. View Article : Google Scholar
|
|
4
|
Morrow JJ and Khanna C: Osteosarcoma
genetics and epigenetics: Emerging biology and candidate therapies.
Crit Rev Oncog. 20:173–197. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Van Wynsberghe PM, Chan SP, Slack FJ and
Pasquinelli AE: Analysis of microRNA expression and function.
Methods Cell Biol. 106:219–252. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Farh KK, Grimson A, Jan C, Lewis BP,
Johnston WK, Lim LP, Burge CB and Bartel DP: The widespread impact
of mammalian MicroRNAs on mRNA repression and evolution. Science.
310:1817–1821. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Mendell JT: MicroRNAs: Critical regulators
of development, cellular physiology and malignancy. Cell Cycle.
4:1179–1184. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Pourrajab F, Babaei Zarch M, BaghiYazdi M,
Hekmatimoghaddam S and Zare-Khormizi MR: MicroRNA-based system in
stem cell reprogramming; differentiation/dedifferentiation. Int J
Biochem Cell Biol. 55:318–328. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Dumortier O, Hinault C and Van Obberghen
E: MicroRNAs and metabolism crosstalk in energy homeostasis. Cell
Metab. 18:312–324. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Frankel LB and Lund AH: MicroRNA
regulation of autophagy. Carcinogenesis. 33:2018–2025. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Tian X, Zhang J, Yan L, Dong JM and Guo Q:
miRNA-15a inhibits proliferation, migration and invasion by
targeting TNFAIP1 in human osteosarcoma cells. Int J Clin Exp
Pathol. 8:6442–6449. 2015.PubMed/NCBI
|
|
12
|
Calin GA, Dumitru CD, Shimizu M, Bichi R,
Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, et al:
Frequent deletions and down-regulation of micro- RNA genes miR15
and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad
Sci USA. 99:15524–15529. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Bonci D, Coppola V, Musumeci M, Addario A,
Giuffrida R, Memeo L, D'Urso L, Pagliuca A, Biffoni M, Labbaye C,
et al: The miR-15a-miR-16-1 cluster controls prostate cancer by
targeting multiple oncogenic activities. Nat Med. 14:1271–1277.
2008. View
Article : Google Scholar : PubMed/NCBI
|
|
14
|
Aqeilan RI, Calin GA and Croce CM: miR-15a
and miR-16-1 in cancer: Discovery, function and future
perspectives. Cell Death Differ. 17:215–220. 2010. View Article : Google Scholar
|
|
15
|
Luo Q, Li X, Li J, Kong X, Zhang J, Chen
L, Huang Y and Fang L: miR-15a is underexpressed and inhibits the
cell cycle by targeting CCNE1 in breast cancer. Int J Oncol.
43:1212–1218. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Shi L, Jackstadt R, Siemens H, Li H,
Kirchner T and Hermeking H: p53-induced miR-15a/16-1 and AP4 form a
double-negative feedback loop to regulate epithelial-mesenchymal
transition and metastasis in colorectal cancer. Cancer Res.
74:532–542. 2014. View Article : Google Scholar
|
|
17
|
Bandi N and Vassella E: miR-34a and
miR-15a/16 are co-regulated in non-small cell lung cancer and
control cell cycle progression in a synergistic and Rb-dependent
manner. Mol Cancer. 10:552011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zhang H, Li L, Liu F, Zhang WY, Wei YZ, Wu
XJ, Xi YY, Zhou YR, Chen HX and Lin YL: Proliferation, migration
and invasion of cervical cancer cells. Xiandai Shengwu Yixue
Jinzhan. 16:2801–2805. 2016.In Chinese.
|
|
19
|
Liu G, Li Y and Gao XG: microRNA-181a is
upregulated in human atherosclerosis plaques and involves in the
oxidative stress-induced endothelial cell dysfunction through
direct targeting Bcl-2. Eur Rev Med Pharmacol Sci. 20:3092–3100.
2016.PubMed/NCBI
|
|
20
|
Zhu DX, Miao KR, Zhu YD, Zhu HY, Fan L,
Liu P, Xu W and Li JY: Detection of miRNA levels in leukemia
patients by real-time quantitative PCR. Zhongguo Shi Yan Xue Ye Xue
Za Zhi. 18:757–761. 2010.In Chinese. PubMed/NCBI
|
|
21
|
Cimmino A, Calin GA, Fabbri M, Iorio MV,
Ferracin M, Shimizu M, Wojcik SE, Aqeilan RI, Zupo S, Dono M, et
al: miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl
Acad Sci USA. 102:13944–13949. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wu MZ, Chen SF, Nieh S, Benner C, Ger LP,
Jan CI, Ma L, Chen CH, Hishida T, Chang HT, et al: Hypoxia drives
breast tumor malignancy through a TET-TNFα-p38-MAPK signaling axis.
Cancer Res. 75:3912–3924. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Deacon K, Onion D, Kumari R, Watson SA and
Knox AJ: Elevated SP-1 transcription factor expression and activity
drives basal and hypoxia-induced vascular endothelial growth factor
(VEGF) expression in non-small cell lung cancer. J Biol Chem.
287:39967–39981. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Hartmann A, Kunz M, Köstlin S, Gillitzer
R, Toksoy A, Bröcker EB and Klein CE: Hypoxia-induced up-regulation
of angiogenin in human malignant melanoma. Cancer Res.
59:1578–1583. 1999.PubMed/NCBI
|
|
25
|
Timani KA, Liu Y, Fan Y, Mohammad KS and
He JJ: Tip110 regulates the cross talk between p53 and
hypoxia-inducible factor 1α under hypoxia and promotes survival of
cancer cells. Mol Cell Biol. 35:2254–2264. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Liu L, Salnikov AV, Bauer N,
Aleksandrowicz E, Labsch S, Nwaeburu C, Mattern J, Gladkich J,
Schemmer P, Werner J, et al: Triptolide reverses hypoxia-induced
epithelial-mesenchymal transition and stem-like features in
pancreatic cancer by NF-κB downregulation. Int J Cancer.
134:2489–2503. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Shimizu S, Eguchi Y, Kosaka H, Kamiike W,
Matsuda H and Tsujimoto Y: Prevention of hypoxia-induced cell death
by Bcl-2 and Bcl-xL. Nature. 374:811–813. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kasar S, Salerno E, Yuan Y, Underbayev C,
Vollenweider D, Laurindo MF, Fernandes H, Bonci D, Addario A,
Mazzella F, et al: Systemic in vivo lentiviral delivery of
miR-15a/16 reduces malignancy in the NZB de novo mouse model of
chronic lymphocytic leukemia. Genes Immun. 13:109–119. 2012.
View Article : Google Scholar :
|
|
29
|
Dai L, Wang W, Zhang S, Jiang Q, Wang R,
Dai L, Cheng L, Yang Y, Wei YQ and Deng HX: Vector-based
miR-15a/16-1 plasmid inhibits colon cancer growth in vivo. Cell
Biol Int. 36:765–770. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Shen G, Li X, Jia YF, Piazza GA and Xi Y:
Hypoxia-regulated microRNAs in human cancer. Acta Pharmacol Sin.
34:336–341. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zuo J, Wen M, Lei M, Peng X, Yang X and
Liu Z: miR-210 links hypoxia with cell proliferation regulation in
human Laryngocarcinoma cancer. J Cell Biochem. 116:1039–1049. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li W, Zhang X, Zhuang H, Chen HG, Chen Y,
Tian W, Wu W, Li Y, Wang S, Zhang L, et al: MicroRNA-137 is a novel
hypoxia-responsive microRNA that inhibits mitophagy via regulation
of two mitophagy receptors FUNDC1 and NIX. J Biol Chem.
289:10691–10701. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yang Y, Ding S, Xu G, Chen F and Ding F:
MicroRNA-15a inhibition protects against
hypoxia/reoxygenation-induced apoptosis of cardiomyocytes by
targeting mothers against decapentaplegic homolog 7. Mol Med Rep.
15:3699–3705. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Xue G, Yan HL, Zhang Y, Hao LQ, Zhu XT,
Mei Q and Sun SH: c-Myc-mediated repression of miR-15-16 in hypoxia
is induced by increased HIF-2α and promotes tumor angiogenesis and
metastasis by upregulating FGF2. Oncogene. 34:1393–1406. 2015.
View Article : Google Scholar
|
|
35
|
Reed JC: Regulation of apoptosis by bcl-2
family proteins and its role in cancer and chemoresistance. Curr
Opin Oncol. 7:541–546. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Pinkas J, Martin SS and Leder P:
Bcl-2-mediated cell survival promotes metastasis of EpH4 betaMEKDD
mammary epithelial cells. Mol Cancer Res. 2:551–556.
2004.PubMed/NCBI
|
|
37
|
Planas-Silva MD, Bruggeman RD, Grenko RT
and Smith JS: Overexpression of c-Myc and Bcl-2 during progression
and distant metastasis of hormone-treated breast cancer. Exp Mol
Pathol. 82:85–90. 2007. View Article : Google Scholar
|
|
38
|
Ricca A, Biroccio A, Del Bufalo D, Mackay
AR, Santoni A and Cippitelli M: bcl-2 over-expression enhances
NF-kappaB activity and induces mmp-9 transcription in human
MCF7(ADR) breast-cancer cells. Int J Cancer. 86:188–196. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Bartel DP: MicroRNAs: Genomics,
biogenesis, mechanism, and function. Cell. 116:281–297. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Wang Y, Li M, Zang W, Ma Y, Wang N, Li P,
Wang T and Zhao G: miR-429 up-regulation induces apoptosis and
suppresses invasion by targeting Bcl-2 and SP-1 in esophageal
carcinoma. Cell Oncol (Dordr). 36:385–394. 2013. View Article : Google Scholar
|
|
41
|
Wu WL, Wang WY, Yao WQ and Li GD:
Suppressive effects of microRNA-16 on the proliferation, invasion
and metastasis of hepatocellular carcinoma cells. Int J Mol Med.
36:1713–1719. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Lerner M, Harada M, Lovén J, Castro J,
Davis Z, Oscier D, Henriksson M, Sangfelt O, Grandér D and Corcoran
MM: DLEU2, frequently deleted in malignancy, functions as a
critical host gene of the cell cycle inhibitory microRNAs miR-15a
and miR-16-1. Exp Cell Res. 315:2941–2952. 2009. View Article : Google Scholar : PubMed/NCBI
|
