|
1
|
Cancer Facts Figures: American Cancer
Society. 2016, https://www.cancer.org/research/cancer-facts-statistics/all-cancer-facts-figures/cancer-facts-figures-2016.html,
Accessed on 11-13-17.
|
|
2
|
Dasari R, De Carvalho A, Medellin DC,
Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La
Chapa JJ, Dybdal-Hargreaves NF, et al: Wittig derivatization of
sesquiterpenoid polygodial leads to cytostatic agents with activity
against drug resistant cancer cells and capable of pyrrolylation of
primary amines. Eur J Med Chem. 103:226–237. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
da Cunha FM, Fröde TS, Mendes GL,
Malheiros A, Cechinel Filho V, Yunes RA and Calixto JB: Additional
evidence for the anti-inflammatory and anti-allergic properties of
the sesquiterpene polygodial. Life Sci. 70:159–169. 2001.
View Article : Google Scholar
|
|
4
|
McCallion RF, Cole AL, Walker JR, Blunt JW
and Munro MH: Antibiotic substances from New Zealand plants. II.
Polygodial, an anti-Candida agent from Pseudowintera colorata.
Planta Med. 44:134–138. 1982. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Barnes CS and Loder JW: Structure of
polygodial-a new sesquiterpene dialdehyde from polygonum hydropiper
L. Aust J Chem. 15:322–327. 1962. View Article : Google Scholar
|
|
6
|
André E, Campi B, Trevisani M, Ferreira J,
Malheiros A, Yunes RA, Calixto JB and Geppetti P: Pharmacological
charac-terisation of the plant sesquiterpenes polygodial and
drimanial as vanilloid receptor agonists. Biochem Pharmacol.
71:1248–1254. 2006. View Article : Google Scholar
|
|
7
|
Kubo I, Fujita K and Lee SH: Antifungal
mechanism of polygodial. J Agric Food Chem. 49:1607–1611. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Leonard CM and Viljoen AM: Warburgia: A
comprehensive review of the botany, traditional uses and
phytochemistry. J Ethnopharmacol. 165:260–285. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Montenegro I, Tomasoni G, Bosio C,
Quiñones N, Madrid A, Carrasco H, Olea A, Martinez R, Cuellar M and
Villena J: Study on the cytotoxic activity of drimane
sesquiterpenes and nordrimane compounds against cancer cell lines.
Molecules. 19:18993–19006. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Just J, Jordan TB, Paull B, Bissember AC
and Smith JA: Practical isolation of polygodial from Tasmannia
lanceolata: A viable scaffold for synthesis. Org Biomol Chem.
13:11200–11207. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Rooney L, Vidal A, D'Souza AM, Devereux N,
Masick B, Boissel V, West R, Head V, Stringer R, Lao J, et al:
Discovery, optimization, and biological evaluation of
5-(2-(trifluoromethyl) phenyl)indazoles as a novel class of
transient receptor potential A1 (TRPA1) antagonists. J Med Chem.
57:5129–5140. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Gonzales CB, De La Chapa JJ, Saikumar P,
Singha PK, Dybdal-Hargreaves NF, Chavez J, Horning AM, Parra J and
Kirma NB: Co-targeting ALK and EGFR parallel signaling in oral
squamous cell carcinoma. Oral Oncol. 59:12–19. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Jensen MM, Jørgensen JT, Binderup T and
Kjaer A: Tumor volume in subcutaneous mouse xenografts measured by
microCT is more accurate and reproducible than determined by
18F-FDG-microPET or external caliper. BMC Med Imaging. 8:162008.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Austah ON, Ruparel NB, Henry MA, Fajardo
RJ, Schmitz JE and Diogenes A: Capsaicin-sensitive innervation
modulates the development of apical periodontitis. J Endod.
42:1496–1502. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Karai L, Brown DC, Mannes AJ, Connelly ST,
Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z and Iadarola MJ:
Deletion of vanilloid receptor 1-expressing primary afferent
neurons for pain control. J Clin Invest. 113:1344–1352. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Anke H and Sterner O: Comparison of the
antimicrobial and cytotoxic activities of twenty unsaturated
sesquiterpene dialdehydes from plants and mushrooms. Planta Med.
57:344–346. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Forsby A, Walum E and Sterner O: The
effect of six sesquiter-penoid unsaturated dialdehydes on cell
membrane permeability in human neuroblastoma SH-SY5Y cells. Chem
Biol Interact. 84:85–95. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Dasari R, De Carvalho A, Medellin DC,
Middleton KN, Hague F, Volmar MN, Frolova LV, Rossato MF, De La
Chapa JJ, Dybdal-Hargreaves NF, et al: Synthetic and biological
studies of sesquiterpene polygodial: Activity of 9-epipolygodial
against drug-resistant cancer cells. ChemMedChem. 10:2014–2026.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Kiso T, Fujita K, Ping X, Tanaka T and
Taniguchi M: Screening for microtubule-disrupting antifungal agents
by using a mitotic-arrest mutant of Aspergillus nidulans and novel
action of phenylalanine derivatives accompanying tubulin loss.
Antimicrob Agents Chemother. 48:1739–1748. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Castelli MV, Lodeyro AF, Malheiros A,
Zacchino SA and Roveri OA: Inhibition of the mitochondrial ATP
synthesis by polygodial, a naturally occurring dialdehyde
unsaturated sesqui-terpene. Biochem Pharmacol. 70:82–89. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Boland ML, Chourasia AH and Macleod KF:
Mitochondrial dysfunction in cancer. Front Oncol. 3:2922013.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Perry SW, Norman JP, Barbieri J, Brown EB
and Gelbard HA: Mitochondrial membrane potential probes and the
proton gradient: A practical usage guide. Biotechniques. 50:98–115.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Haynes CM, Titus EA and Cooper AA:
Degradation of misfolded proteins prevents ER-derived oxidative
stress and cell death. Mol Cell. 15:767–776. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Malhotra JD, Miao H, Zhang K, Wolfson A,
Pennathur S, Pipe SW and Kaufman RJ: Antioxidants reduce
endoplasmic reticulum stress and improve protein secretion. Proc
Natl Acad Sci USA. 105:18525–18530. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Zeeshan HM, Lee GH, Kim HR and Chae HJ:
Endoplasmic Reticulum Stress and Associated ROS. Int J Mol Sci.
17:3272016. View Article : Google Scholar : PubMed/NCBI
|
