|
1
|
Chen Q, Cao HZ and Zheng PS: LGR5 promotes
the proliferation and tumor formation of cervical cancer cells
through the Wnt/β-catenin signaling pathway. Oncotarget.
5:9092–9105. 2014.PubMed/NCBI
|
|
2
|
Chung SH, Wiedmeyer K, Shai A, Korach KS
and Lambert PF: Requirement for estrogen receptor alpha in a mouse
model for human papillomavirus-associated cervical cancer. Cancer
Res. 68:9928–9934. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Riera-Leal A, Ramirez De Arellano A,
Ramirez-Lopez IG, Lopez-Pulido EI, Davila Rodriguez JR,
Macias-Barragan JG, Ortiz-Lazareno PC, Jave-Suárez LF,
Artaza-Irigaray C, Del Toro Arreola S, et al: Effects of 60 kDa
prolactin and estradiol on metabolism and cell survival in cervical
cancer: Coexpression of their hormonal receptors during cancer
progression. Oncol Rep. 40:3781–3793. 2018.PubMed/NCBI
|
|
4
|
Otto AM: Warburg effect(s)-a biographical
sketch of otto warburg and his impacts on tumor metabolism. Cancer
Metab. 4:52016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Asgari Y, Zabihinpour Z, Salehzadeh-Yazdi
A, Schreiber F and Masoudi-Nejad A: Alterations in cancer cell
metabolism: The warburg effect and metabolic adaptation. Genomics.
105:275–281. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wu M, Neilson A, Swift AL, Moran R,
Tamagnine J, Parslow D, Armistead S, Lemire K, Orrell J, Teich J,
et al: Multiparameter metabolic analysis reveals a close link
between attenuated mitochondrial bioenergetic function and enhanced
glycolysis dependency in human tumor cells. Am J Physiol Cell
Physiol. 292:C125–C136. 2007. View Article : Google Scholar
|
|
7
|
Chen JQ, Yager JD and Russo J: Regulation
of mitochondrial respiratory chain structure and function by
estrogens/estrogen receptors and potential
physiological/pathophysiological implications. Biochim Biophys
Acta. 1746:1–17. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Paterni I, Granchi C, Katzenellenbogen JA
and Minutolo F: Estrogen receptors alpha (ERα) and beta (ERβ):
Subtype-selective ligands and clinical potential. Steroids.
90:13–29. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen JQ, Cammarata PR, Baines CP and Yager
JD: Regulation of mitochondrial respiratory chain biogenesis by
estrogens/estrogen receptors and physiological, pathological and
pharmacological implications. Biochim Biophys Acta. 1793:1540–1570.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Simpkins JW, Yang SH, Sarkar SN and Pearce
V: Estrogen actions on mitochondria-physiological and pathological
implications. Mol Cell Endocrinol. 290:51–59. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Ribas V, Drew BG, Zhou Z, Phun J, Kalajian
NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim
TQ, et al: Skeletal muscle action of estrogen receptor alpha is
critical for the maintenance of mitochondrial function and
metabolic homeostasis in females. Sci Transl Med. 8:334ra542016.
View Article : Google Scholar
|
|
12
|
Lobaton CD, Vay L, Hernandez-Sanmiguel E,
Santodomingo J, Moreno A, Montero M and Alvarez J: Modulation of
mitochondrial Ca(2+) uptake by estrogen receptor agonists and
antagonists. Br J Pharmacol. 145:862–871. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Palsson-McDermott EM and O'Neill LA: The
Warburg effect then and now: From cancer to inflammatory diseases.
BioEssays. 35:965–973. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Liu YQ, Zhang GA, Zhang BC, Wang Y, Liu Z,
Jiao YL, Liu N and Zhao YR: Short low concentration cisplatin
treatment leads to an epithelial mesenchymal transition-like
response in DU145 prostate cancer cells. Asian Pac J Cancer Prev.
16:1025–1028. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chen Y, Wang S, Bu S, Xu M and Lai D:
Low-dose cisplatin-induced CXCR4 expression promotes proliferation
of ovarian cancer stem-like cells. Acta Biochim Biophys Sin
(Shanghai). 48:282–289. 2016. View Article : Google Scholar
|
|
16
|
Dodt M, Roehr JT, Ahmed R and Dieterich C:
FLEXBAR-flexible barcode and adapter processing for next-generation
sequencing platforms. Biology (Basel). 1:895–905. 2012.
|
|
17
|
Bray NL, Pimentel H, Melsted P and Pachter
L: Near-optimal probabilistic RNA-seq quantification. Nat
Biotechnol. 34:525–527. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Love MI, Huber W and Anders S: Moderated
estimation of fold change and dispersion for RNA-seq data with
DESeq2. Genome Biol. 15:5502014. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Mi H, Muruganujan A, Ebert D, Huang X and
Thomas PD: PANTHER version 14: More genomes, a new PANTHER GO-slim
and improvements in enrichment analysis tools. Nucleic Acids Res.
47:D419–D426. 2019. View Article : Google Scholar :
|
|
20
|
Kanehisa M and Goto S: KEGG: Kyoto
encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30.
2000. View Article : Google Scholar
|
|
21
|
Kanehisa M, Sato Y, Furumichi M, Morishima
K and Tanabe M: New approach for understanding genome variations in
KEGG. Nucleic Acids Res. 47:D590–D595. 2019. View Article : Google Scholar :
|
|
22
|
Latunde-Dada GO: Ferroptosis: Role of
lipid peroxidation, iron and ferritinophagy. Biochim Biophys Acta
Gen Subj. 1861:1893–1900. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chen K, Liu H, Liu Z, Bloomer W, Amos CI,
Lee JE, Li X, Nan H and Wei Q: Genetic variants in glutamine
metabolic pathway genes predict cutaneous melanoma-specific
survival. Mol Carcinog. 2019.Epub ahead of print. View Article : Google Scholar
|
|
24
|
Cheng M, Bhujwalla ZM and Glunde K:
Targeting phospholipid metabolism in cancer. Front Oncol.
6:2662016. View Article : Google Scholar
|
|
25
|
Zou RC, Xiao SF, Shi ZT, Ke Y, Tang HR, Wu
TG, Guo ZT, Ni F, Li WX and Wang L: Identification of
metabolism-associated pathways and genes involved in male and
female liver cancer patients. J Theor Biol. 480:218–228. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ikhlas S and Ahmad M: Metformin: Insights
into its anticancer potential with special reference to AMPK
dependent and independent pathways. Life Sci. 185:53–62. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Tyszka-Czochara M, Bukowska-Strakova K and
Majka M: Metformin and caffeic acid regulate metabolic
reprogramming in human cervical carcinoma SiHa/HTB-35 cells and
augment anticancer activity of Cisplatin via cell cycle regulation.
Food Chem Toxicol. 106:260–272. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Wang T, Liu B, Guan Y, Gong M, Zhang W,
Pan J, Liu Y, Liang R, Yuan Y and Ye L: Melatonin inhibits the
proliferation of breast cancer cells induced by bisphenol A via
targeting estrogen receptor-related pathways. Thorac Cancer.
9:368–375. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Vallance P and Chan N: Endothelial
function and nitric oxide: Clinical relevance. Heart. 85:342–350.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Chiueh C, Lee S, Andoh T and Murphy D:
Induction of anti-oxidative and antiapoptotic thioredoxin supports
neuroprotective hypothesis of estrogen. Endocrine. 21:27–31. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Ronchetti SA, Machiavelli LI, Quinteros
FA, Duvilanski BH and Cabilla JP: Nitric oxide plays a key role in
ovariectomy-induced apoptosis in anterior pituitary: Interplay
between nitric oxide pathway and estrogen. PLoS One.
11:e01624552016. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Schmidt AJ, Krieg J and Vedder H:
Differential effects of gluco-corticoids and gonadal steroids on
glutathione levels in neuronal and glial cell systems. J Neurosci
Res. 67:544–550. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Schapira A and Lodi R: Assessment of in
vitro and in vivo mitochondrial function in Friedreich's ataxia and
Huntington's disease. Methods Mol Biol. 277:293–307.
2004.PubMed/NCBI
|
|
34
|
Yang X, Xu MM, Wang J and Xie JX: Effect
of estrogen on iron metabolism in mammals. Sheng Li Xue Bao.
68:637–643. 2016.PubMed/NCBI
|
|
35
|
Chen B, Li GF, Shen Y, Huang XI and Xu YJ:
Reducing iron accumulation: A potential approach for the prevention
and treatment of postmenopausal osteoporosis. Exp Ther Med.
10:7–11. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Xie Q, Xi G, Keep RF and Hua Y: Effects of
gender and estrogen receptors on iron-induced brain edema
formation. Acta Neurochir Suppl. 121:341–345. 2016. View Article : Google Scholar
|
|
37
|
Asano M, Yamasaki K, Yamauchi T, Terui T
and Aiba S: Epidermal iron metabolism for iron salvage. J Dermatol
Sci. 87:101–109. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
El-Rifaie AA, Sabry D, Doss RW, Kamal MA
and Abd El Hassib DM: Heme oxygenase and iron status in exosomes of
psoriasis patients. Arch Dermatol Res. 310:651–656. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Miniaci MC, Irace C, Capuozzo A, Piccolo
M, Di Pascale A, Russo A, Lippiello P, Lepre F, Russo G and
Santamaria R: Cysteine prevents the reduction in keratin synthesis
induced by iron deficiency in human keratinocytes. J Cell Biochem.
117:402–412. 2016. View Article : Google Scholar
|
|
40
|
Pelle E, Jian J, Zhang Q, Muizzuddin N,
Yang Q, Dai J, Maes D, Pernodet N, Yarosh DB, Frenkel K and Huang
X: Menopause increases the iron storage protein ferritin in skin. J
Cosmet Sci. 64:175–179. 2013.PubMed/NCBI
|
|
41
|
Roberts and Szego CM: The influence of
steroids on uterine respiration and glycolysis. J Biol Chem.
201:21–30. 1953.PubMed/NCBI
|
|
42
|
Faulds MH, Zhao C, Dahlman-Wright K and
Gustafsson JÅ: The diversity of sex steroid action: Regulation of
metabolism by estrogen signaling. J Endocrinol. 212:3–12. 2012.
View Article : Google Scholar
|
|
43
|
Chen X, Qian Y and Wu S: The Warburg
effect: Evolving interpretations of an established concept. Free
Radic Biol Med. 79:253–263. 2015. View Article : Google Scholar
|
|
44
|
Liberti MV and Locasale JW: The warburg
effect: How does it benefit cancer cells? Trends Biochem Sci.
41:211–218. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Potter M; Newport E; Morten KJ: The
warburg effect: 80 years on. Biochem Soc Trans. 44:1499–1505. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Jhingran A, Russell AH, Seiden MV, Duska
LR, Goodman A, Lee SL, et al: 84-Cancers of the Cervix, Vulva, and
Vagina. Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH and
Tepper JE: Abeloff's Clinical Oncology (Sixth Edition)
Philadelphia: Content Repository Only; 2020, pp. 1468–1507.e8
|
|
47
|
Valle A, Català-Niell A, Colom B,
García-Palmer FJ, Oliver J and Roca P: Sex-related differences in
energy balance in response to caloric restriction. Am J Physiol
Endocrinol Metab. 289:E15–E22. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Demonacos CV, Karayanni N, Hatzoglou E,
Tsiriyiotis C, Spandidos DA and Sekeris CE: Mitochondrial genes as
sites of primary action of steroid hormones. Steroids. 61:226–232.
1996. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Chen JQ, Eshete M, Alworth WL and Yager
JD: Binding of MCF-7 cell mitochondrial proteins and recombinant
human estrogen receptors alpha and beta to human mitochondrial DNA
estrogen response elements. J Cell Biochem. 93:358–373. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Zhai P, Eurell TE, Cooke PS, Lubahn DB and
Gross DR: Myocardial ischemia-reperfusion injury in estrogen
receptor-alpha knockout and wild-type mice. Am J Physiol Heart Circ
Physiol. 278:H1640–H1647. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Zhai P, Eurell TE, Cotthaus R, Jeffery EH,
Bahr JM and Gross DR: Effect of estrogen on global myocardial
ischemia-reperfusion injury in female rats. Am J Physiol Heart Circ
Physiol. 279:H2766–H2775. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Thompson CJ, Tam NN, Joyce JM, Leav I and
Ho SM: Gene expression profiling of testosterone and estradiol-17
beta-induced prostatic dysplasia in Noble rats and response to the
antiestrogen ICI 182-780. Endocrinology. 143:2093–2105. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Weisz A, Basile W, Scafoglio C, Altucci L,
Bresciani F, Facchiano A, Sismondi P, Cicatiello L and De Bortoli
M: Molecular identification of ERalpha-positive breast cancer cells
by the expression profile of an intrinsic set of estrogen regulated
genes. J Cell Physiol. 200:440–450. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Wang J, Green PS and Simpkins JW:
Estradiol protects against ATP depletion, mitochondrial membrane
potential decline and the generation of reactive oxygen species
induced by 3-nitroproprionic acid in SK-N-SH human neuroblastoma
cells. J Neurochem. 77:804–811. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Nilsen J and Brinton RD: Mitochondria as
therapeutic targets of estrogen action in the central nervous
system. Curr Drug Targets CNS Neurol Disord. 3:297–313. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Berg JM, Tymoczko JL, Gatto GJ and Stryer
L: Biochemistry. 2015.
|
|
57
|
Kim NH, Cha YH, Lee J, Lee SH, Yang JH,
Yun JS, Cho ES, Zhang X, Nam M, Kim N, et al: Snail reprograms
glucose metabolism by repressing phosphofructokinase PFKP allowing
cancer cell survival under metabolic stress. Nat Commun.
8:143742017. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Glunde K, Jie C and Bhujwalla ZM:
Molecular causes of the aberrant choline phospholipid metabolism in
breast cancer. Cancer Res. 64:4270–4276. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Palmisano BT, Zhu L and Stafford JM: Role
of estrogens in the regulation of liver lipid metabolism. Adv Exp
Med Biol. 1043:227–256. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Di Croce L, Vicent GP, Pecci A, Bruscalupi
G, Trentalance A and Beato M: The promoter of the rat
3-hydroxy-3-methylgl-utaryl coenzyme A reductase gene contains a
tissue-specific estrogen-responsive region. Mol Endocrinol.
13:1225–1236. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Wang D, Zhu W, Wang Y, Yan J, Teng M, Miao
J and Zhou Z: Metabolomics approach to investigate estrogen
receptor-dependent and independent effects of o, p'-DDT in the
uterus and brain of immature mice. J Agric Food Chem. 65:3609–3616.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Marín-Hernández A, Gallardo-Pérez JC,
Ralph SJ, Rodríguez-Enríquez S and Moreno-Sánchez R: HIF-1alpha
modulates energy metabolism in cancer cells by inducing
over-expression of specific glycolytic isoforms. Mini Rev Med Chem.
9:1084–1101. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Zhang X, Ma L, Qi J, Shan H, Yu W and Gu
Y: MAPK/ERK signaling pathway-induced hyper-O-GlcNAcylation
enhances cancer malignancy. Mol Cell Biochem. 410:101–110. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Han J, Zhang L, Guo H, Wysham WZ, Roque
DR, Willson AK, Sheng X, Zhou C and Bae-Jump VL: Glucose promotes
cell proliferation, glucose uptake and invasion in endometrial
cancer cells via AMPK/mTOR/S6 and MAPK signaling. Gynecol Oncol.
138:668–675. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Cao M, Jiang J, Du Y and Yan P:
Mitochondria-targeted antioxidant attenuates high glucose-induced
P38 MAPK pathway activation in human neuroblastoma cells. Mol Med
Rep. 5:929–934. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Faubert B, Boily G, Izreig S, Griss T,
Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B, et
al: AMPK is a negative regulator of the Warburg effect and
suppresses tumor growth in vivo. Cell Metab. 17:113–124. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Lipovka Y, Chen H, Vagner J, Price TJ,
Tsao TS and Konhilas JP: Oestrogen receptors interact with the
α-catalytic subunit of AMP-activated protein kinase. Biosci Rep.
35:e002642015. View Article : Google Scholar
|
|
68
|
Linher-Melville K, Zantinge S and Singh G:
Liver kinase B1 expression (LKB1) is repressed by estrogen receptor
alpha (ERα) in MCF-7 human breast cancer cells. Biochem Biophys Res
Commun. 417:1063–1068. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Artaza-Irigaray C, Molina-Pineda A,
Aguilar-Lemarroy A, Ortiz-Lazareno P, Limón-Toledo LP,
Pereira-Suárez AL, Rojo-Contreras W and Jave-Suárez LF: E6/E7 and
E6* from HPV16 and HPV18 upregulate IL-6 expression independently
of p53 in keratinocytes. Front Immunol. 10:16762019. View Article : Google Scholar
|
|
70
|
Bridges HR, Sirviö VA, Agip AN and Hirst
J: Molecular features of biguanides required for targeting of
mitochondrial respiratory complex I and activation of AMP-kinase.
BMC Biol. 14:652016. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Brown KA, Hunger NI, Docanto M and Simpson
ER: Metformin inhibits aromatase expression in human breast adipose
stromal cells via stimulation of AMP-activated protein kinase.
Breast Cancer Res Treat. 123:591–596. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Zhang J, Zhang B, Yin Z, Chen F, Liu T, Xu
H, Liu Y and Zhou X: Effects of metformin on the estrogen-induced
proliferation and the expression of ER in human endometrial cancer
cells. Zhonghua Fu Chan Ke Za Zhi. 49:932–937. 2014.In Chinese.
|
|
73
|
Kim J, Lee J, Jang SY, Kim C, Choi Y and
Kim A: Anticancer effect of metformin on estrogen receptor-positive
and tamoxifen-resistant breast cancer cell lines. Oncol Rep.
35:2553–2560. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Scherbakov AM, Sorokin DV, Tatarskiy VV
Jr, Prokhorov NS, Semina SE, Berstein LM and Krasil'nikov MA: The
phenomenon of acquired resistance to metformin in breast cancer
cells: The interaction of growth pathways and estrogen receptor
signaling. IUBMB Life. 68:281–292. 2016. View Article : Google Scholar : PubMed/NCBI
|
