Emerging roles of non‑coding RNAs in the response of rectal cancer to radiotherapy (Review)
Corrigendum in: /10.3892/ijo.2021.5247
- Authors:
- Huyen Trang Ha Thi
- Hong‑Quan Duong
- Suntaek Hong
-
Affiliations: Faculty of Biotechnology, Chemistry and Environmental Engineering, Phenikaa University, Hanoi 100000, Vietnam, Laboratory Center, Hanoi University of Public Health, Hanoi 100000, Vietnam, Laboratory of Cancer Cell Biology, Department of Biochemistry, Gachon University School of Medicine, Incheon 21999, Republic of Korea - Published online on: January 22, 2021 https://doi.org/10.3892/ijo.2021.5175
- Pages: 344-358
This article is mentioned in:
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|
Miller KD, Siegel RL, Lin CC, Mariotto AB, Kramer JL, Rowland JH, Stein KD, Alteri R and Jemal A: Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 66:271–289. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Giuliani ME, Lindsay PE, Kwan JY, Sun A, Bezjak A, Le LW, Brade A, Cho J, Leighl NB, Shepherd FA and Hope AJ: Correlation of dosimetric and clinical factors with the development of esophagitis and radiation pneumonitis in patients with limited-stage small-cell lung carcinoma. Clin Lung Cancer. 16:216–220. 2015. View Article : Google Scholar | |
|
Han S, Gu F, Lin G, Sun X, Wang Y, Wang Z, Lin Q, Weng D, Xu Y and Mao W: Analysis of clinical and dosimetric factors influencing radiation-induced lung injury in patients with lung cancer. J Cancer. 6:1172–1178. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Briere TM, Krafft S, Liao Z and Martel MK: Lung size and the risk of radiation pneumonitis. Int J Radiat Oncol Biol Phys. 94:377–384. 2016. View Article : Google Scholar | |
|
Podralska M, Ciesielska S, Kluiver J, van den Berg A, Dzikiewicz-Krawczyk A and Slezak-Prochazka I: Non-coding RNAs in cancer radiosensitivity: MicroRNAs and lncRNAs as regulators of radiation-induced signaling pathways. Cancers (Basel). 12:16622020. View Article : Google Scholar | |
|
Dreussi E, Pucciarelli S, De Paoli A, Polesel J, Canzonieri V, Agostini M, Friso ML, Belluco C, Buonadonna A, Lonardi S, et al: Predictive role of microRNA-related genetic polymorphisms in the pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients. Oncotarget. 7:19781–19793. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Fanale D, Castiglia M, Bazan V and Russo A: Involvement of non-coding RNAs in chemo- and radioresistance of colorectal cancer. Adv Exp Med Biol. 937:207–228. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Bartel DP: MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell. 116:281–297. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Chen CZ: MicroRNAs as oncogenes and tumor suppressors. N Engl J Med. 353:1768–1771. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Tan S, Xia L, Yi P, Han Y, Tang L, Pan Q, Tian Y, Rao S, Oyang L, Liang J, et al: Exosomal miRNAs in tumor microenvironment. J Exp Clin Cancer Res. 39:672020. View Article : Google Scholar : PubMed/NCBI | |
|
Patil N, Allgayer H and Leupold JH: MicroRNAs in the tumor microenvironment. Adv Exp Med Biol. 1277:1–31. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Kosaka N, Iguchi H and Ochiya T: Circulating microRNA in body fluid: A new potential biomarker for cancer diagnosis and prognosis. Cancer Sci. 101:2087–2092. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Movahedpour A, Ahmadi N, Ghasemi Y, Savardashtaki A and Shabaninejad Z: Circulating microRNAs as potential diagnostic biomarkers and therapeutic targets in prostate cancer: Current status and future perspectives. J Cell Biochem. 120:16316–16329. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Sohel MH: Extracellular/circulating MicroRNAs: Release mechanisms, functions and challenges. Achiev Life Sci. 10:175–186. 2016. | |
|
Mercer TR, Dinger ME and Mattick JS: Long non-coding RNAs: Insights into functions. Nat Rev Genet. 10:155–159. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Fernandes JCR, Acuña SM, Aoki JI, Floeter-Winter LM and Muxel SM: Long non-coding RNAs in the regulation of gene expression: Physiology and disease. Noncoding RNA. 5:172019. | |
|
Statello L, Guo CJ, Chen LL and Huarte M: Gene regulation by long non-coding RNAs and its biological functions. Nat Rev Mol Cell Biol. Dec 22–2020.Epub ahead of print. PubMed/NCBI | |
|
Spizzo R, Almeida MI, Colombatti A and Calin GA: Long non-coding RNAs and cancer: A new frontier of translational research? Oncogene. 31:4577–4587. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Schmitt AM and Chang HY: Long noncoding RNAs in cancer pathways. Cancer Cell. 29:452–463. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Liu K, Gao L, Ma X, Huang JJ, Chen J, Zeng L, Ashby CR Jr, Zou C and Chen ZS: Long non-coding RNAs regulate drug resistance in cancer. Mol Cancer. 19:542020. View Article : Google Scholar : PubMed/NCBI | |
|
Zhu Y, Zhao Y, Dong S, Liu L, Tai L and Xu Y: Systematic identification of dysregulated lncRNAs associated with platinum-based chemotherapy response across 11 cancer types. Genomics. 112:1214–1222. 2020. View Article : Google Scholar | |
|
Huang L, Zeng L, Chu J, Xu P, Lv M, Xu J, Wen J, Li W, Wang L, Wu X, et al: Chemoresistance-related long non-coding RNA expression profiles in human breast cancer cells. Mol Med Rep. 18:243–253. 2018.PubMed/NCBI | |
|
Arnold M, Sierra MS, Laversanne M, Soerjomataram I, Jemal A and Bray F: Global patterns and trends in colorectal cancer incidence and mortality. Gut. 66:683–691. 2017. View Article : Google Scholar | |
|
Siegel RL, Miller KD, Goding Sauer A, Fedewa SA, Butterly LF, Anderson JC, Cercek A, Smith RA and Jemal A: Colorectal cancer statistics, 2020. CA Cancer J Clin. 70:145–164. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Siegel R, Desantis C and Jemal A: Colorectal cancer statistics, 2014. CA Cancer J Clin. 64:104–117. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Lo AC, Soliman AS, Khaled HM, Aboelyazid A and Greenson JK: Lifestyle, occupational, and reproductive factors and risk of colorectal cancer. Dis Colon Rectum. 53:830–837. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Basen-Engquist K and Chang M: Obesity and cancer risk: Recent review and evidence. Curr Oncol Rep. 13:71–76. 2011. View Article : Google Scholar | |
|
De Roos AJ, Ray RM, Gao DL, Fitzgibbons ED, Ziding F, Astrakianakis G, Thomas DB and Checkoway H: Colorectal cancer incidence among female textile workers in Shanghai, China: A case-cohort analysis of occupational exposures. Cancer Causes Control. 16:1177–1188. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Oddone E, Modonesi C and Gatta G: Occupational exposures and colorectal cancers: A quantitative overview of epidemiological evidence. World J Gastroenterol. 20:12431–12444. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Rattray NJW, Charkoftaki G, Rattray Z, Hansen JE, Vasiliou V and Johnson CH: Environmental influences in the etiology of colorectal cancer: The premise of metabolomics. Curr Pharmacol Rep. 3:114–125. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Peters RK, Garabrant DH, Yu MC and Mack TM: A case-control study of occupational and dietary factors in colorectal cancer in young men by subsite. Cancer Res. 49:5459–5468. 1989.PubMed/NCBI | |
|
Wang Y, Lewis-Michl EL, Hwang SA, Fitzgerald EF and Stark AD: Cancer incidence among a cohort of female farm residents in New York State. Arch Environ Health. 57:561–567. 2002. View Article : Google Scholar | |
|
Wesseling C, Antich D, Hogstedt C, Rodríguez AC and Ahlbom A: Geographical differences of cancer incidence in Costa Rica in relation to environmental and occupational pesticide exposure. Int J Epidemiol. 28:365–374. 1999. View Article : Google Scholar : PubMed/NCBI | |
|
Rushton L, Hutchings S and Brown T: The burden of cancer at work: Estimation as the first step to prevention. Occup Environ Med. 65:789–800. 2008. View Article : Google Scholar | |
|
Toiyama Y and Kusunoki M: Changes in surgical therapies for rectal cancer over the past 100 years: A review. Ann Gastroenterol Surg. 4:331–342. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Knol J and Keller DS: Total mesorectal excision technique-past, present, and future. Clin Colon Rectal Surg. 33:134–143. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Kapiteijn E, Marijnen CA, Nagtegaal ID, Putter H, Steup WH, Wiggers T, Rutten HJ, Pahlman L, Glimelius B, van Krieken JH, et al: Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med. 345:638–646. 2001. View Article : Google Scholar : PubMed/NCBI | |
|
Sauer R, Becker H, Hohenberger W, Rödel C, Wittekind C, Fietkau R, Martus P, Tschmelitsch J, Hager E, Hess CF, et al: Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med. 351:1731–1740. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Roeder F, Meldolesi E, Gerum S, Valentini V and Rödel C: Recent advances in (chemo-)radiation therapy for rectal cancer: A comprehensive review. Radiat Oncol. 15:2622020. View Article : Google Scholar : PubMed/NCBI | |
|
Heald RJ, Husband EM and Ryall RD: The mesorectum in rectal cancer surgery-the clue to pelvic recurrence? Br J Surg. 69:613–616. 1982. View Article : Google Scholar : PubMed/NCBI | |
|
Hermanek P, Hermanek P, Hohenberger W, Klimpfinger M, Köckerling F and Papadopoulos T: The pathological assessment of mesorectal excision: Implications for further treatment and quality management. Int J Colorectal Dis. 18:335–341. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
MacFarlane JK, Ryall RD and Heald RJ: Mesorectal excision for rectal cancer. Lancet. 341:457–460. 1993. View Article : Google Scholar : PubMed/NCBI | |
|
Havenga K, Enker WE, Norstein J, Moriya Y, Heald RJ, van Houwelingen HC and van de Velde CJ: Improved survival and local control after total mesorectal excision or D3 lymph-adenectomy in the treatment of primary rectal cancer: An international analysis of 1411 patients. Eur J Surg Oncol. 25:368–374. 1999. View Article : Google Scholar : PubMed/NCBI | |
|
Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer. Medical research council rectal cancer working party Lancet. 348:1605–1610. 1996. | |
|
Kim SH, Lee JM, Hong SH, Kim GH, Lee JY, Han JK and Choi BI: Locally advanced rectal cancer: Added value of diffusion-weighted MR imaging in the evaluation of tumor response to neoadjuvant chemo- and radiation therapy. Radiology. 253:116–125. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Christou N, Meyer J, Toso C, Ris F and Buchs NC: Lateral lymph node dissection for low rectal cancer: Is it necessary? World J Gastroenterol. 25:4294–4299. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Benson AB, Venook AP, Al-Hawary MM, Arain MA, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Garrido-Laguna I, et al: NCCN Guidelines insights: Rectal cancer, version 6.2020. J Natl Compr Canc Netw. 18:806–815. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang S, Bai W, Tong X, Bu P, Xu J and Xi Y: Correlation between tumor microenvironment-associated factors and the efficacy and prognosis of neoadjuvant therapy for rectal cancer. Oncol Lett. 17:1062–1070. 2019.PubMed/NCBI | |
|
Ma B, Gao P, Song Y, Huang X, Wang H, Xu Q, Zhao S and Wang Z: Short-course radiotherapy in neoadjuvant treatment for rectal cancer: A systematic review and meta-analysis. Clin Colorectal Cancer. 17:320–330.e5. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Bujko K, Wyrwicz L, Rutkowski A, Malinowska M, Pietrzak L, Kryński J, Michalski W, Olędzki J, Kuśnierz J, Zając L, et al: Long-course oxaliplatin-based preoperative chemoradiation versus 5×5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: Results of a randomized phase III study. Ann Oncol. 27:834–842. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
From the American Association of Neurological Surgeons (AANS); American Society of Neuroradiology (ASNR); Canadian Interventional Radiology Association (CIRA); Congress of Neurological Surgeons (CNS); European Society of Minimally Invasive Neurological Therapy (ESMINT); European Society of Neuroradiology (ESNR); European Stroke Organization (ESO); Society for Cardiovascular Angiography; Interventions (SCAI); Society of Interventional Radiology (SIR); Society of Interventional Radiology (SIR); et al: Multisociety consensus quality improvement revised consensus statement for endovascular therapy of acute ischemic stroke. Int J Stroke. 13:612–632. 2018.PubMed/NCBI | |
|
Ngan SY, Burmeister B, Fisher RJ, Solomon M, Goldstein D, Joseph D, Ackland SP, Schache D, McClure B, McLachlan SA, et al: Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman radiation oncology group trial 01.04. J Clin Oncol. 30:3827–3833. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
McLachlan SA, Fisher RJ, Zalcberg J, Solomon M, Burmeister B, Goldstein D, Leong T, Ackland SP, McKendrick J, McClure B, et al: The impact on health-related quality of life in the first 12 months: A randomised comparison of preoperative short-course radiation versus long-course chemoradiation for T3 rectal cancer (Trans-Tasman Radiation Oncology Group Trial 01.04). Eur J Cancer. 55:15–26. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Mowery YM, Salama JK, Zafar SY, Moore HG, Willett CG, Czito BG, Hopkins MB and Palta M: Neoadjuvant long-course chemoradiation remains strongly favored over short-course radiotherapy by radiation oncologists in the United States. Cancer. 123:1434–1441. 2017. View Article : Google Scholar | |
|
Glynne-Jones R, Wyrwicz L, Tiret E, Brown G, Rödel C, Cervantes A and Arnold D; ESMO Guidelines Committee: Rectal cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 29(Suppl 4): iv2632018. View Article : Google Scholar : PubMed/NCBI | |
|
Sineshaw HM, Jemal A, Thomas CR Jr and Mitin T: Changes in treatment patterns for patients with locally advanced rectal cancer in the United States over the past decade: An analysis from the national cancer data base. Cancer. 122:1996–2003. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Wang X, Zheng B, Lu X, Bai R, Feng L, Wang Q, Zhao Y and He S: Preoperative short-course radiotherapy and long-course radiochemotherapy for locally advanced rectal cancer: Meta-analysis with trial sequential analysis of long-term survival data. PLoS One. 13:e02001422018. View Article : Google Scholar : PubMed/NCBI | |
|
Otero de Pablos J and Mayol J: Controversies in the management of lateral pelvic lymph nodes in patients with advanced rectal cancer: East or west? Front Surg. 6:792019. View Article : Google Scholar | |
|
Watanabe T, Muro K, Ajioka Y, Hashiguchi Y, Ito Y, Saito Y, Hamaguchi T, Ishida H, Ishiguro M, Ishihara S, et al: Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer. Int J Clin Oncol. 23:1–34. 2018. View Article : Google Scholar : | |
|
Tokuhara K, Ueyama Y, Nakatani K, Yoshioka K and Kon M: Outcomes of neoadjuvant chemoradiotherapy in Japanese locally advanced rectal carcinoma patients. World J Surg Oncol. 14:1362016. View Article : Google Scholar : PubMed/NCBI | |
|
Numasaki H, Shibuya H, Nishio M, Ikeda H, Sekiguchi K, Kamikonya N, Koizumi M, Tago M, Ando Y, Tsukamoto N, et al: Japanese structure survey of radiation oncology in 2007 with special reference to designated cancer care hospitals. Strahlenther Onkol. 187:167–174. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Teshima T, Numasaki H, Shibuya H, Nishio M, Ikeda H, Sekiguchi K, Kamikonya N, Koizumi M, Tago M, Ando Y, et al: Japanese structure survey of radiation oncology in 2007 based on institutional stratification of patterns of care study. Int J Radiat Oncol Biol Phys. 78:1483–1493. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Minsky BD, Cohen AM, Enker WE, Sigurdson E and Harrison LB: Radiation therapy for unresectable rectal cancer. Int J Radiat Oncol Biol Phys. 21:1283–1289. 1991. View Article : Google Scholar : PubMed/NCBI | |
|
Wang G, Wang W, Jin H, Dong H, Chen W, Li X, Li G and Li L: The effect of primary tumor radiotherapy in patients with unresectable stage IV rectal or rectosigmoid cancer: A propensity score matching analysis for survival. Radiat Oncol. 15:1262020. View Article : Google Scholar : PubMed/NCBI | |
|
van der Valk MJM, Hilling DE, Bastiaannet E, Meershoek-Klein Kranenbarg E, Beets GL, Figueiredo NL, Habr-Gama A, Perez RO, Renehan AG and van de Velde CJH: IWWD Consortium: Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the international watch & wait database (IWWD): An international multicentre registry study. Lancet. 391:2537–2545. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhao F, Wang J, Yu H, Cheng X, Li X, Zhu X, Xu X, Lin J, Chen X and Yan S: Neoadjuvant radiotherapy improves overall survival for T3/4N+M0 rectal cancer patients: A population-based study of 20300 patients. Radiat Oncol. 15:492020. View Article : Google Scholar : PubMed/NCBI | |
|
Petrelli F, Trevisan F, Cabiddu M, Sgroi G, Bruschieri L, Rausa E, Ghidini M and Turati L: Total neoadjuvant therapy in rectal cancer: A systematic review and meta-analysis of treatment outcomes. Ann Surg. 271:440–448. 2020. View Article : Google Scholar | |
|
Cercek A, Roxburgh CSD, Strombom P, Smith JJ, Temple LKF, Nash GM, Guillem JG, Paty PB, Yaeger R, Stadler ZK, et al: Adoption of total neoadjuvant therapy for locally advanced rectal cancer. JAMA Oncol. 4:e1800712018. View Article : Google Scholar : PubMed/NCBI | |
|
Gilshtein H, Ghuman A, Dawoud M, Yellinek S, Kent I, Sharp SP, Nagarajan A and Wexner SD: Total neoadjuvant treatment for rectal cancer: Preliminary experience. Am Surg. Nov 10–2020.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
|
den Dulk M, Krijnen P, Marijnen CA, Rutten HJ, van de Poll-Franse LV, Putter H, Meershoek-Klein Kranenbarg E, Jansen-Landheer ML, Coebergh JW and van de Velde CJ: Improved overall survival for patients with rectal cancer since 1990: The effects of TME surgery and pre-operative radio-therapy. Eur J Cancer. 44:1710–1716. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Birgisson H, Påhlman L, Gunnarsson U and Glimelius B: Late adverse effects of radiation therapy for rectal cancer-a systematic overview. Acta Oncol. 46:504–516. 2007. View Article : Google Scholar | |
|
Bruheim K, Guren MG, Skovlund E, Hjermstad MJ, Dahl O, Frykholm G, Carlsen E and Tveit KM: Late side effects and quality of life after radiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys. 76:1005–1011. 2010. View Article : Google Scholar | |
|
Joye I and Haustermans K: Early and late toxicity of radiotherapy for rectal cancer. Recent Results Cancer Res. 203:189–201. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Marijnen CA, Kapiteijn E, van de Velde CJ, Martijn H, Steup WH, Wiggers T, Kranenbarg EK and Leer JW; Cooperative Investigators of the Dutch Colorectal Cancer Group: Acute side effects and complications after short-term preoperative radio-therapy combined with total mesorectal excision in primary rectal cancer: Report of a multicenter randomized trial. J Clin Oncol. 20:817–825. 2002. View Article : Google Scholar : PubMed/NCBI | |
|
Frykholm GJ, Isacsson U, Nygård K, Montelius A, Jung B, Påhlman L and Glimelius B: Preoperative radiotherapy in rectal carcinoma-aspects of acute adverse effects and radiation technique. Int J Radiat Oncol Biol Phys. 35:1039–1048. 1996. View Article : Google Scholar : PubMed/NCBI | |
|
Sipaviciute A, Sileika E, Burneckis A and Dulskas A: Late gastrointestinal toxicity after radiotherapy for rectal cancer: A systematic review. Int J Colorectal Dis. 35:977–983. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Swedish Rectal Cancer Trial; Cedermark B, Dahlberg M, Glimelius B, Påhlman L, Rutqvist LE and Wilking N: Improved survival with preoperative radiotherapy in resectable rectal cancer. N Engl J Med. 336:980–987. 1997. View Article : Google Scholar : PubMed/NCBI | |
|
van Gijn W, Marijnen CA, Nagtegaal ID, Kranenbarg EM, Putter H, Wiggers T, Rutten HJ, Påhlman L, Glimelius B and van de Velde CJ; Dutch Colorectal Cancer Group: Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial. Lancet Oncol. 12:575–582. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Randomized study on preoperative radiotherapy in rectal carcinoma. Stockholm colorectal cancer study group. Ann Surg Oncol. 3:423–430. 1996. View Article : Google Scholar : PubMed/NCBI | |
|
Birgisson H, Påhlman L, Gunnarsson U and Glimelius B; Swedish Rectal Cancer Trial Group: Adverse effects of preoperative radiation therapy for rectal cancer: Long-term follow-up of the Swedish rectal cancer trial. J Clin Oncol. 23:8697–8705. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Peeters KC, van de Velde CJ, Leer JW, Martijn H, Junggeburt JM, Kranenbarg EK, Steup WH, Wiggers T, Rutten HJ and Marijnen CA: Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: Increased bowel dysfunction in irradiated patients-a Dutch colorectal cancer group study. J Clin Oncol. 23:6199–6206. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Pollack J, Holm T, Cedermark B, Altman D, Holmström B, Glimelius B and Mellgren A: Late adverse effects of short-course preoperative radiotherapy in rectal cancer. Br J Surg. 93:1519–1525. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Marijnen CA, van de Velde CJ, Putter H, van den Brink M, Maas CP, Martijn H, Rutten HJ, Wiggers T, Kranenbarg EK, Leer JW and Stiggelbout AM: Impact of short-term preoperative radiotherapy on health-related quality of life and sexual functioning in primary rectal cancer: Report of a multicenter randomized trial. J Clin Oncol. 23:1847–1858. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Frykholm GJ, Glimelius B and Påhlman L: Preoperative or postoperative irradiation in adenocarcinoma of the rectum: Final treatment results of a randomized trial and an evaluation of late secondary effects. Dis Colon Rectum. 36:564–572. 1993. View Article : Google Scholar : PubMed/NCBI | |
|
Shi Y, Liu N, Lai W, Yan B, Chen L, Liu S, Liu S, Wang X, Xiao D, Liu X, et al: Nuclear EGFR-PKM2 axis induces cancer stem cell-like characteristics in irradiation-resistant cells. Cancer Lett. 422:81–93. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Yan B, Liu S, Shi Y, Liu N, Chen L, Wang X, Xiao D, Liu X, Mao C, Jiang Y, et al: Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radio-resistance. Cell Death Dis. 9:4902018. View Article : Google Scholar | |
|
Rycaj K and Tang DG: Cancer stem cells and radioresistance. Int J Radiat Biol. 90:615–621. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Li F, Zhou K, Gao L, Zhang B, Li W, Yan W, Song X, Yu H, Wang S, Yu N and Jiang Q: Radiation induces the generation of cancer stem cells: A novel mechanism for cancer radioresistance. Oncol Lett. 12:3059–3065. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Hartley A, Ho KF, McConkey C and Geh JI: Pathological complete response following pre-operative chemoradiotherapy in rectal cancer: Analysis of phase II/III trials. Br J Radiol. 78:934–938. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Sinukumar S, Patil P, Engineer R, Desouza A and Saklani A: Clinical outcome of patients with complete pathological response to neoadjuvant chemoradiotherapy for locally advanced rectal cancers: The Indian scenario. Gastroenterol Res Pract. 2014:8678412014. View Article : Google Scholar | |
|
Valentini V, Aristei C, Glimelius B, Minsky BD, Beets-Tan R, Borras JM, Haustermans K, Maingon P, Overgaard J, Pahlman L, et al: Multidisciplinary rectal cancer management: 2nd European rectal cancer consensus conference (EURECA-CC2). Radiother Oncol. 92:148–163. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Gérard JP, Conroy T, Bonnetain F, Bouché O, Chapet O, Closon-Dejardin MT, Untereiner M, Leduc B, Francois E, Maurel J, et al: Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3-4 rectal cancers: Results of FFCD 9203. J Clin Oncol. 24:4620–4625. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Yoon WH, Kim HJ, Kim CH, Joo JK, Kim YJ and Kim HR: Oncologic impact of pathologic response on clinical outcome after preoperative chemoradiotherapy in locally advanced rectal cancer. Ann Surg Treat Res. 88:15–20. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Pozo ME and Fang SH: Watch and wait approach to rectal cancer: A review. World J Gastrointest Surg. 7:306–312. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Renehan AG, Malcomson L, Emsley R, Gollins S, Maw A, Myint AS, Rooney PS, Susnerwala S, Blower A, Saunders MP, et al: Watch-and-wait approach versus surgical resection after chemoradiotherapy for patients with rectal cancer (the OnCoRe project): A propensity-score matched cohort analysis. Lancet Oncol. 17:174–183. 2016. View Article : Google Scholar | |
|
Chan N, Milosevic M and Bristow RG: Tumor hypoxia, DNA repair and prostate cancer progression: New targets and new therapies. Future Oncol. 3:329–341. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Anastasiadou E, Jacob LS and Slack FJ: Non-coding RNA networks in cancer. Nat Rev Cancer. 18:5–18. 2018. View Article : Google Scholar | |
|
Zhu J, Chen S, Yang B, Mao W, Yang X and Cai J: Molecular mechanisms of lncRNAs in regulating cancer cell radiosensitivity. Biosci Rep. 39:BSR201905902019. View Article : Google Scholar : PubMed/NCBI | |
|
Sole C, Arnaiz E, Manterola L, Otaegui D and Lawrie CH: The circulating transcriptome as a source of cancer liquid biopsy biomarkers. Semin Cancer Biol. 58:100–108. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Li N, Yu J, Luo A, Tang Y, Liu W, Wang S, Liu Y, Song Y, Fang H, Chen B, et al: LncRNA and mRNA signatures associated with neoadjuvant chemoradiotherapy downstaging effects in rectal cancer. J Cell Biochem. 120:5207–5217. 2019. View Article : Google Scholar | |
|
Liz J and Esteller M: lncRNAs and microRNAs with a role in cancer development. Biochim Biophys Acta. 1859:169–176. 2016. View Article : Google Scholar | |
|
Cao MX, Jiang YP, Tang YL and Liang XH: The crosstalk between lncRNA and microRNA in cancer metastasis: Orchestrating the epithelial-mesenchymal plasticity. Oncotarget. 8:12472–12483. 2017. View Article : Google Scholar : | |
|
Ferrando L, Cirmena G, Garuti A, Scabini S, Grillo F, Mastracci L, Isnaldi E, Marrone C, Gonella R, Murialdo R, et al: Development of a long non-coding RNA signature for prediction of response to neoadjuvant chemoradiotherapy in locally advanced rectal adenocarcinoma. PLoS One. 15:e02265952020. View Article : Google Scholar : PubMed/NCBI | |
|
Wang ZK, Yang L, Wu LL, Mao H, Zhou YH, Zhang PF and Dai GH: Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy. Braz J Med Biol Res. 51:e67932017. View Article : Google Scholar : PubMed/NCBI | |
|
Liao J and Dong LP: Linc00261 suppresses growth and metastasis of non-small cell lung cancer via repressing epithelial-mesenchymal transition. Eur Rev Med Pharmacol Sci. 23:3829–3837. 2019.PubMed/NCBI | |
|
Fang Q, Sang L and Du S: Long noncoding RNA LINC00261 regulates endometrial carcinoma progression by modulating miRNA/FOXO1 expression. Cell Biochem Funct. 36:323–330. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Drebber U, Lay M, Wedemeyer I, Vallböhmer D, Bollschweiler E, Brabender J, Mönig SP, Hölscher AH, Dienes HP and Odenthal M: Altered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapy. Int J Oncol. 39:409–415. 2011.PubMed/NCBI | |
|
Zhu H, Zhu X, Cheng G, Zhou M and Lou W: Downregulation of microRNA-21 enhances radiosensitivity in nasopharyngeal carcinoma. Exp Ther Med. 9:2185–2189. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Huang Q: Predictive relevance of ncRNAs in non-small-cell lung cancer patients with radiotherapy: A review of the published data. Biomark Med. 12:1149–1159. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Lopes-Ramos CM, Habr-Gama A, Quevedo Bde S, Felício NM, Bettoni F, Koyama FC, Asprino PF, Galante PA, Gama-Rodrigues J, Camargo AA, et al: Overexpression of miR-21-5p as a predictive marker for complete tumor regression to neoadjuvant chemoradiotherapy in rectal cancer patients. BMC Med Genomics. 7:682014. View Article : Google Scholar : PubMed/NCBI | |
|
Caramés C, Cristóbal I, Moreno V, del Puerto L, Moreno I, Rodriguez M, Marín JP, Correa AV, Hernández R, Zenzola V, et al: MicroRNA-21 predicts response to preoperative chemoradiotherapy in locally advanced rectal cancer. Int J Colorectal Dis. 30:899–906. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Svoboda M, Izakovicova Holla L, Sefr R, Vrtkova I, Kocakova I, Tichy B and Dvorak J: Micro-RNAs miR125b and miR137 are frequently upregulated in response to capecitabine chemoradiotherapy of rectal cancer. Int J Oncol. 33:541–547. 2008.PubMed/NCBI | |
|
D'Angelo E, Fassan M, Maretto I, Pucciarelli S, Zanon C, Digito M, Rugge M, Nitti D and Agostini M: Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma. Oncotarget. 7:28647–28657. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Yu J, Li N, Wang X, Ren H, Wang W, Wang S, Song Y, Liu Y, Li Y, Zhou X, et al: Circulating serum microRNA-345 correlates with unfavorable pathological response to preoperative chemo-radiotherapy in locally advanced rectal cancer. Oncotarget. 7:64233–64243. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Caramés C, Cristobal I, Moreno V, Marín JP, González-Alonso P, Torrejón B, Minguez P, Leon A, Martín JI, Hernández R, et al: MicroRNA-31 emerges as a predictive biomarker of pathological response and outcome in locally advanced rectal cancer. Int J Mol Sci. 17:8782016. View Article : Google Scholar : | |
|
Chiang Y, Song Y, Wang Z, Liu Z, Gao P, Liang J, Zhu J, Xing C and Xu H: microRNA-192, -194 and -215 are frequently down-regulated in colorectal cancer. Exp Ther Med. 3:560–566. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Wang B, Shen ZL, Gao ZD, Zhao G, Wang CY, Yang Y, Zhang JZ, Yan YC, Shen C, Jiang KW, et al: MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway. Cell Cycle. 14:1046–1058. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Zhao Y, Li F, Zhang X, Liu A, Qi J, Cui H and Zhao P: MicroRNA-194 acts as a prognostic marker and inhibits proliferation in hepatocellular carcinoma by targeting MAP4K4. Int J Clin Exp Pathol. 8:12446–12454. 2015. | |
|
D'Angelo E, Zanon C, Sensi F, Digito M, Rugge M, Fassan M, Scarpa M, Pucciarelli S, Nitti D and Agostini M: miR-194 as predictive biomarker of responsiveness to neoadjuvant chemoradiotherapy in patients with locally advanced rectal adenocarcinoma. J Clin Pathol. 71:344–350. 2018. View Article : Google Scholar | |
|
Slotta-Huspenina J, Drecoll E, Feith M, Habermehl D, Combs S, Weichert W, Bettstetter M, Becker K and Langer R: MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus. J Transl Med. 16:1092018. View Article : Google Scholar : PubMed/NCBI | |
|
Du B, Wang X, Wu D, Wang T, Yang X, Wang J, Shi X, Chen L and Zhang W: MicroRNA expression profiles identify biomarkers for predicting the response to chemoradiotherapy in rectal cancer. Mol Med Rep. 18:1909–1916. 2018.PubMed/NCBI | |
|
Della Vittoria Scarpati G, Falcetta F, Carlomagno C, Ubezio P, Marchini S, De Stefano A, Singh VK, D'Incalci M, De Placido S and Pepe S: A specific miRNA signature correlates with complete pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 83:1113–1119. 2012. View Article : Google Scholar | |
|
Hotchi M, Shimada M, Kurita N, Iwata T, Sato H, Morimoto S, Yoshikawa K, Higashijima J and Miyatani T: microRNA expression is able to predict response to chemoradiotherapy in rectal cancer. Mol Clin Oncol. 1:137–142. 2013.PubMed/NCBI | |
|
Kheirelseid EA, Miller N, Chang KH, Curran C, Hennessey E, Sheehan M, Newell J, Lemetre C, Balls G and Kerin MJ: miRNA expressions in rectal cancer as predictors of response to neoadjuvant chemoradiation therapy. Int J Colorectal Dis. 28:247–260. 2013. View Article : Google Scholar | |
|
Svoboda M, Sana J, Fabian P, Kocakova I, Gombosova J, Nekvindova J, Radova L, Vyzula R and Slaby O: MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients. Radiat Oncol. 7:1952012. View Article : Google Scholar : PubMed/NCBI | |
|
Calanzani N, Druce PE, Snudden C, Milley KM, Boscott R, Behiyat D, Saji S, Martinez-Gutierrez J, Oberoi J, Funston G, et al: Identifying novel biomarkers ready for evaluation in low-prevalence populations for the early detection of upper gastrointestinal cancers: A systematic review. Adv Ther. Dec 11–2020.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI | |
|
Azizian A, Epping I, Kramer F, Jo P, Bernhardt M, Kitz J, Salinas G, Wolff HA, Grade M, Beißbarth T, et al: Prognostic value of MicroRNAs in preoperative treated rectal cancer. Int J Mol Sci. 17:5682016. View Article : Google Scholar : PubMed/NCBI | |
|
Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, Shinomura Y and Tokino T: Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res. 68:4123–4132. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Campayo M, Navarro A, Benítez JC, Santasusagna S, Ferrer C, Monzó M and Cirera L: miR-21, miR-99b and miR-375 combination as predictive response signature for preoperative chemoradiotherapy in rectal cancer. PLoS One. 13:e02065422018. View Article : Google Scholar : PubMed/NCBI | |
|
Machackova T, Trachtova K, Prochazka V, Grolich T, Farkasova M, Fiala L, Sefr R, Kiss I, Skrovina M, Dosoudil M, et al: Tumor microRNAs identified by small RNA sequencing as potential response predictors in locally advanced rectal cancer patients treated with neoadjuvant chemoradiotherapy. Cancer Genomics Proteomics. 17:249–257. 2020. View Article : Google Scholar : PubMed/NCBI | |
|
Li AL, Chung TS, Chan YN, Chen CL, Lin SC, Chiang YR, Lin CH, Chen CC and Ma N: microRNA expression pattern as an ancillary prognostic signature for radiotherapy. J Transl Med. 16:3412018. View Article : Google Scholar : PubMed/NCBI | |
|
Rupaimoole R and Slack FJ: MicroRNA therapeutics: Towards a new era for the management of cancer and other diseases. Nat Rev Drug Discov. 16:203–222. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Renganathan A and Felley-Bosco E: Long noncoding RNAs in cancer and therapeutic potential. Adv Exp Med Biol. 1008:199–222. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Guzel E, Okyay TM, Yalcinkaya B, Karacaoglu S, Gocmen M and Akcakuyu MH: Tumor suppressor and oncogenic role of long non-coding RNAs in cancer. North Clin Istanb. 7:81–86. 2019. | |
|
Zhang H, Chen Z, Wang X, Huang Z, He Z and Chen Y: Long non-coding RNA: A new player in cancer. J Hematol Oncol. 6:372013. View Article : Google Scholar : PubMed/NCBI | |
|
Rasool M, Malik A, Zahid S, Basit Ashraf MA, Qazi MH, Asif M, Zaheer A, Arshad M, Raza A and Jamal MS: Non-coding RNAs in cancer diagnosis and therapy. Noncoding RNA Res. 1:69–76. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Dizaji BF: Strategies to target long non-coding RNAs in cancer treatment: Progress and challenges. Egypt J Med Hum Genet. 21:412020. View Article : Google Scholar | |
|
Yang N: An overview of viral and nonviral delivery systems for microRNA. Int J Pharm Investig. 5:179–181. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Labatut AE and Mattheolabakis G: Non-viral based miR delivery and recent developments. Eur J Pharm Biopharm. 128:82–90. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Zhang Y, Wang Z and Gemeinhart RA: Progress in microRNA delivery. J Control Release. 172:962–974. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Meng WJ, Yan H, Zhou B, Zhang W, Kong XH, Wang R, Zhan L, Li Y, Zhou ZG and Sun XF: Correlation of SATB1 overexpression with the progression of human rectal cancer. Int J Colorectal Dis. 27:143–150. 2012. View Article : Google Scholar | |
|
Zhang P, Wang L, Rodriguez-Aguayo C, Yuan Y, Debeb BG, Chen D, Sun Y, You MJ, Liu Y, Dean DC, et al: miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13. Nat Commun. 5:56712014. View Article : Google Scholar : PubMed/NCBI | |
|
Huang X, Taeb S, Jahangiri S, Emmenegger U, Tran E, Bruce J, Mesci A, Korpela E, Vesprini D, Wong CS, et al: miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1. Cancer Res. 73:6972–6986. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Ha Thi HT, Kim HY, Kim YM and Hong S: MicroRNA-130a modulates a radiosensitivity of rectal cancer by targeting SOX4. Neoplasia. 21:882–892. 2019. View Article : Google Scholar : PubMed/NCBI | |
|
Kelley KA, Ruhl RA, Rana SR, Dewey E, Espinosa C, Thomas CR Jr, Martindale RG, Anand S and Tsikitis VL: Understanding and resetting radiation sensitivity in rectal cancer. Ann Surg. 266:610–616. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Ruhl R, Rana S, Kelley K, Espinosa-Diez C, Hudson C, Lanciault C, Thomas CR Jr, Liana Tsikitis V and Anand S: microRNA-451a regulates colorectal cancer proliferation in response to radiation. BMC Cancer. 18:5172018. View Article : Google Scholar : PubMed/NCBI | |
|
Luo J, Liu L, Zhou N, Shen J, Sun Q, Zhu Y and Chen M: miR-519b-3p promotes responsiveness to preoperative chemo-radiotherapy in rectal cancer patients by targeting ARID4B. Gene. 655:84–90. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Winter SF, Lukes L, Walker RC, Welch DR and Hunter KW: Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis. PLoS Genet. 8:e10027352012. View Article : Google Scholar : PubMed/NCBI | |
|
Yang P, Yang Y, An W, Xu J, Zhang G, Jie J and Zhang Q: The long noncoding RNA-ROR promotes the resistance of radiotherapy for human colorectal cancer cells by targeting the p53/miR-145 pathway. J Gastroenterol Hepatol. 32:837–845. 2017. View Article : Google Scholar | |
|
Zou Y, Yao S, Chen X, Liu D, Wang J, Yuan X, Rao J, Xiong H, Yu S, Yuan X, et al: LncRNA OIP5-AS1 regulates radioresistance by targeting DYRK1A through miR-369-3p in colorectal cancer cells. Eur J Cell Biol. 97:369–378. 2018. View Article : Google Scholar : PubMed/NCBI | |
|
Wang G, Li Z, Zhao Q, Zhu Y, Zhao C, Li X, Ma Z, Li X and Zhang Y: LincRNA-p21 enhances the sensitivity of radiotherapy for human colorectal cancer by targeting the Wnt/β-catenin signaling pathway. Oncol Rep. 31:1839–1845. 2014. View Article : Google Scholar : PubMed/NCBI |
