[Corrigendum] LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells <em>in vitro</em> and <em>in vivo</em> through enhancing PDGFRβ signaling

Xiao,Qungen; Dong,Minhai; Cheng,Fangling; Mao,Feng; Zong,Weifeng; Wu,Kang; Wang,Heping; Xie,Ruifan; Wang,Baofeng; Lei,Ting; Guo,Dongsheng

doi:10.3892/ijo.2022.5305

February-2022 Volume 60 Issue 2

Full Size Image

Cover Legend PDF

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

An International Open Access Journal Devoted to General Medicine.

February-2022 Volume 60 Issue 2

Full Size Image

Cover Legend PDF

Correction Open Access

[Corrigendum] LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling

Authors:
- Qungen Xiao
- Minhai Dong
- Fangling Cheng
- Feng Mao
- Weifeng Zong
- Kang Wu
- Heping Wang
- Ruifan Xie
- Baofeng Wang
- Ting Lei
- Dongsheng Guo
View Affiliations / Copyright

Affiliations: Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, P.R. China

Copyright: © Xiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 15
|
Published online on: January 10, 2022

https://doi.org/10.3892/ijo.2022.5305
Expand metrics +

Article

Int J Oncol 53: [Related article:] 1069-1082, 2018; DOI: 10.3892/ijo.2018.4482

Subsequently to the publication of the above article and a Corrigendum that addressed the issue of a misspelling of one of the authors' names (DOI: 10.3892/ijo.2019.4769; published online on April 2, 2019), the authors have subsequently discovered that Fig. 7 on p. 1079 contained a duplication in two of the panels that might cause the readers some confusion. The authors were able to re-examine the original data, repeat the experiment, and have decided to revise Fig. 7.

Figure 7

LRIG2 enhances the activation of PDGFRβ and regulates its downstream pathways and effectors in vivo. A total of four groups of indicated stable U87 glioblastoma cells (U87-LRIG2, LRIG2 -overexpressing; U87-Con, control U87 cells; U87-LRIG2-sh, LRIG2-knockdown cells; and U87-scr, scramble U87 cells) were injected subcutaneously into the flanks of mice with severe combined immunodeficiency. At the end of the animal experiments, tumor xenografts were isolated and immunohistochemistry was performed to evaluate the expression of LRIG2, PDGFRβ and its downstream pathways, as indicated. Representative images are depicted (scale bars, 20 μm). LRIG2, leucine-rich repeats and immunoglobulin-like domain 2; PDGFRβ, platelet-derived growth factor receptor β.

The corrected version of Fig. 7, showing replacement data for the p-Akt and Cyclin D1 experiments, is shown on the next page. The authors confirm that these data continue to support the main conclusions presented in their paper, and are grateful to the Editor of International Journal of Oncology for allowing them this opportunity to publish a Corrigendum. They also apologize to the readership for any inconvenience caused.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Corrigendum] LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling

This article is mentioned in:

Article

Figure 7

Figure 7

Related Articles