|
1
|
Bray F, Ferlay J, Soerjomataram I, Siegel
RL, Torre LA and Jemal A: Global cancer statistics 2018: GLOBOCAN
estimates of incidence and mortality worldwide for 36 cancers in
185 countries. CA Cancer J Clin. 68:394–424. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Jacobs IJ and Menon U: Progress and
challenges in screening for early detection of ovarian cancer. Mol
Cell Proteomics. 3:355–366. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Ebell MH, Culp MB and Radke TJ: A
systematic review of symptoms for the diagnosis of ovarian cancer.
Am J Prev Med. 50:384–394. 2016. View Article : Google Scholar
|
|
4
|
Matulonis UA, Sood AK, Fallowfield L,
Howitt BE, Sehouli J and Karlan BY: Ovarian cancer. Nat Rev Dis
Primers. 2:160612016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Prat J, D'Angelo E and Espinosa I: Ovarian
carcinomas: At least five different diseases with distinct
histological features and molecular genetics. Hum Pathol. 80:11–27.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang Y, Hong S, Mu J, Wang Y, Lea J, Kong
B and Zheng W: Tubal origin of 'ovarian' low-grade serous
carcinoma: A gene expression profile study. J Oncol.
2019:86597542019. View Article : Google Scholar
|
|
7
|
Hao D, Li J, Jia S, Meng Y, Zhang C, Wang
L and Di LJ: Integrated analysis reveals tubaland
ovarian-originated serous ovarian cancer and predicts differential
therapeutic responses. Clin Cancer Res. 23:7400–7411. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kotsopoulos IC, Papanikolaou A,
Lambropoulos AF, Papazisis KT, Tsolakidis D, Touplikioti P and
Tarlatzis BC: Serous ovarian cancer signaling pathways. Int J
Gynecol Cancer. 24:410–417. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen Q, Gao G and Luo S: Hedgehog
signaling pathway and ovarian cancer. Chin J Cancer Res.
25:346–353. 2013.PubMed/NCBI
|
|
10
|
Szkandera J, Kiesslich T, Haybaeck J,
Gerger A and Pichler M: Hedgehog signaling pathway in ovarian
cancer. Int J Mol Sci. 14:1179–1196. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Jeng KS, Chang CF and Lin SS: Sonic
hedgehog signaling in organogenesis, tumors, and tumor
microenvironments. Int J Mol Sci. 21:7582020. View Article : Google Scholar :
|
|
12
|
Skoda AM, Simovic D, Karin V, Kardum V,
Vranic S and Serman L: The role of the hedgehog signaling pathway
in cancer: A comprehensive review. Bosn J Basic Med Sci. 18:8–20.
2018. View Article : Google Scholar :
|
|
13
|
Ryan KE and Chiang C: Hedgehog secretion
and signal transduction in vertebrates. J Biol Chem.
287:17905–17913. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Hanna A and Shevde LA: Hedgehog signaling:
Modulation of cancer properies and tumor mircroenvironment. Mol
Cancer. 15:242016. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Guo YY, Zhang JY, Li XF, Luo HY, Chen F
and Li TJ: PTCH1 gene mutations in keratocystic odontogenic tumors:
A study of 43 Chinese patients and a systematic review. PLoS One.
8:e773052013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Rudolf AF, Kinnebrew M, Kowatsch C, Ansell
TB, El Omari K, Bishop B, Pardon E, Schwab RA, Malinauskas T, Qian
M, et al: The morphogen Sonic hedgehog inhibits its receptor
patched by a pincer grasp mechanism. Nat Chem Biol. 15:975–982.
2019. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Fleet AJ and Hamel PA: The
protein-specific activities of the transmembrane modules of Ptch1
and Ptch2 are determined by their adjacent protein domains. J Biol
Chem. 293:16583–16595. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Riobo-Del Galdo NA, Lara Montero Á and
Wertheimer EV: Role of hedgehog signaling in breast cancer:
Pathogenesis and therapeutics. Cells. 8:3752019. View Article : Google Scholar :
|
|
19
|
Shimokawa T, Svärd J, Heby-Henricson K,
Teglund S, Toftgård R and Zaphiropoulos PG: Distinct roles of first
exon variants of the tumor-suppressor patched1 in hedgehog
signaling. Oncogene. 26:4889–4896. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Wils LJ and Bijlsma MF: Epigenetic
regulation of the hedgehog and Wnt pathways in cancer. Crit Rev
Oncol Hematol. 121:23–44. 2018. View Article : Google Scholar
|
|
21
|
Chung JH and Bunz F: A loss-of-function
mutation in PTCH1 suggests a role for autocrine hedgehog signaling
in colorectal tumorigenesis. Oncotarget. 4:2208–2211. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Wang CY, Chang YC, Kuo YL, Lee KT, Chen
PS, Cheung CHA, Chang CP, Phan NN, Shen MR and Hsu HP: Mutation of
the PTCH1 gene predicts recurrence of breast cancer. Sci Rep.
9:163592019. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Musani V, Sabol M, Car D, Ozretic P,
Oreskovic S, Leovic D and Levanat S: LOH of PTCH1 region in BCC and
ovarian carcinoma: Microsatellite vs HRM analysis. Front Biosci
(Elite Ed). 4:1049–1057. 2012.
|
|
24
|
McGarvey TW, Maruta Y, Tomaszewski JE,
Linnenbach AJ and Malkowicz SB: PTCH gene mutations in invasive
transitional cell carcinoma of the bladder. Oncogene. 17:1167–1172.
1998. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Heitzer E, Bambach I, Dandachi N, Horn M
and Wolf P: PTCH promoter methylation at low level in sporadic
basal cell carcinoma analysed by three different approaches. Exp
Dermatol. 19:926–928. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Sinha S, Singh RK, Alam N, Roy A,
Roychoudhury S and Panda CK: Alterations in candidate genes PHF2,
FANCC, PTCH1 and XPA at chromosomal 9q22.3 region: Pathological
significance in early- and late-onset breast carcinoma. Mol Cancer.
7:842008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zuo Y, Song Y, Zhang M, Xu Z and Qian X:
Role of PTCH1 gene methylation in gastric carcinogenesis. Oncol
Lett. 8:679–682. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Im S, Choi HJ, Yoo C, Jung JH, Jeon YW,
Suh YJ and Kang CS: Hedgehog related protein expression in breast
cancer: gli-2 is associated with poor overall survival. Korean J
Pathol. 47:116–123. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Gonnissen A, Isebaert S, Perneel C, McKee
CM, Van Utterbeeck F, Lerut E, Verrill C, Bryant RJ, Joniau S,
Muschel RJ and Haustermans K: Patched 1 expression correlates with
biochemical relapse in high-risk prostate cancer patients. Am J
Pathol. 188:795–804. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Hasanovic A and Mus-Veteau I: Targeting
the multidrug transporter Ptch1 potentiates chemotherapy
efficiency. Cells. 7:1072018. View Article : Google Scholar :
|
|
31
|
Chen X, Horiuchi A, Kikuchi N, Osada R,
Yoshida J, Shiozawa T and Konishi I: Hedgehog signal pathway is
activated in ovarian carcinomas, correlating with cell
proliferation: It's inhibition leads to growth suppression and
apoptosis. Cancer Sci. 98:68–76. 2007. View Article : Google Scholar
|
|
32
|
Liao X, Siu MK, Au CW, Wong ES, Chan HY,
Ip PP, Ngan HY and Cheung AN: Aberrant activation of hedgehog
signaling pathway in ovarian cancers: Effect on prognosis, cell
invasion and differentiation. Carcinogenesis. 30:131–140. 2009.
View Article : Google Scholar
|
|
33
|
Bhattacharya R, Kwon J, Ali B, Wang E,
Patra S, Shridhar V and Mukherjee P: Role of hedgehog signaling in
ovarian cancer. Clin Cancer Res. 14:7659–7666. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zheng F, Xiao X and Wang C: The effect of
PTCH1 on ovarian cancer cell proliferation and apoptosis. Cancer
Biother Radiopharm. 34:103–109. 2019. View Article : Google Scholar
|
|
35
|
Kardum V, Karin V, Glibo M, Skrtic A,
Martic TN, Ibisevic N, Skenderi F, Vranic S and Serman L:
Methylation-associated silencing of SFRP1 gene in high-grade serous
ovarian carcinomas. Ann Diagn Pathol. 31:45–49. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Karin-Kujundzic V, Kardum V, Sola IM, Paic
F, Skrtic A, Skenderi F, Serman A, Nikuseva-Martic T, Vranic S and
Serman L: Dishevelled family proteins in serous ovarian carcinomas:
A clinicopathologic and molecular study. APMIS. 128:201–210. 2020.
View Article : Google Scholar
|
|
37
|
Vrsalovic MM, Korac P, Dominis M, Ostojic
S, Mannhalter C and Kusec R: T- and B-cell clonality and frequency
of human herpes viruses-6, -8 and Epstein Barr virus in
angioimmunoblastic T-cell lymphoma. Hematol Oncol. 22:169–177.
2004. View Article : Google Scholar
|
|
38
|
Peng L, Hu J, Li S, Wang Z, Xia B, Jiang
B, Li B, Zhang Y, Wang J and Wang X: Aberrant methylation of the
PTCH1 gene promoter region in aberrant crypt foci. Int J Cancer.
132:E18–E25. 2013. View Article : Google Scholar
|
|
39
|
McDonald D, Carrero G, Andrin C, de Vries
G and Hendzel MJ: Nucleoplasmic beta-actin exists in a dynamic
equilibrium between low-mobility polymeric species and rapidly
diffusing populations. J Cell Biol. 172:541–552. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Hoock TC, Newcomb PM and Herman IM: Beta
actin and its mRNA are localized at the plasma membrane and the
regions of moving cytoplasm during the cellular response to injury.
J Cell Biol. 112:653–664. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Acharya P, Quinlan A and Neumeister V: The
ABCs of finding a good antibody: How to find a good antibody,
validate it, and publish meaningful data. F1000Res. 6:8512017.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Pak E and Segal RA: Hedgehog signal
transduction: Key players, oncogenic drivers, and cancer therapy.
Dev Cell. 38:333–344. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Carpenter G: Nuclear localization and
possible functions of receptor tyrosine kinases. Curr Opin Cell
Biol. 15:143–148. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Anido J, Scaltriti M, Bech Serra JJ,
Santiago Josefat B, Todo FR, Baselga J and Arribas J: Biosynthesis
of tumorigenic HER2 C-terminal fragments by alternative initiation
of translation. EMBO J. 25:3234–3244. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Kagawa H, Shino Y, Kobayashi D, Demizu S,
Shimada M, Ariga H and Kawahara H: A novel signaling pathway
mediated by the nuclear targeting of C-terminal fragments of
mammalian patched 1. PLoS One. 6:e186382011. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Cretnik M, Musani V, Oreskovic S, Leovic D
and Levanat S: The patched gene is epigenetically regulated in
ovarian dermoids and fibromas, but not in basocellular carcinomas.
Int J Mol Med. 19:875–883. 2007.PubMed/NCBI
|
|
47
|
Löf-Öhlin ZM, Levanat S, Sabol M, Sorbe B
and Nilsson TK: Promoter methylation in the PTCH gene in cervical
epithelial cancer and ovarian cancer tissue as studied by eight
novel Pyrosequencing® assays. Int J Oncol. 38:685–692.
2011.
|
