Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 1019-6439 Online ISSN: 1791-2423
Journal Cover
January-2023 Volume 62 Issue 1

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
January-2023 Volume 62 Issue 1

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML

  • Supplementary Files
    • Supplementary_Data.pdf
Article Open Access

Overcharged lipid metabolism in mechanisms of antitumor by Tremella fuciformis‑derived polysaccharide

  • Authors:
    • Xiumin Li
    • Qiaoling Su
    • Yutian Pan
  • View Affiliations / Copyright

    Affiliations: The Engineering Technological Center of Mushroom Industry, Minnan Normal University, Zhangzhou, Fujian 363000, P.R. China
    Copyright: © Li et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 11
    |
    Published online on: November 23, 2022
       https://doi.org/10.3892/ijo.2022.5459
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Tremella fuciformis‑derived polysaccharide (TFP) is a natural macromolecular compound that is well known for whitening skin, as well as for its ability to regulate lipids and immunity. However, its mechanism of action is not clear. In the present study, B16 cells treated with TFP were inoculated subcutaneously in the right flank of C57BL/6 mice to explore the effect of TFP on melanoma in vivo. Western blotting, immunohistochemistry, immunofluorescence staining and transcription analysis of tumors were utilized to assess the expression of key molecules in production of melanin, lipid metabolism and immunity. It was found that TFP promoted B16 cell apoptosis and induced G2/M cell cycle arrest, which was associated with activation of cell cycle‑related pathways. TFP induced the expression of glucose transporter type 4 and CD36, thus resulting in an increase in the uptake of lipids, which markedly suppressed sterol regulatory element‑binding transcription factor 1 and phosphorylated‑AMP‑activated protein kinase expression; increased the number of lipids in the cell membrane, endoplasmic reticulum and nucleus; and induced the RNA expression of molecules related to lipid metabolism, as revealed by RNA‑sequencing in vivo. Increased lipid binding, upregulated lipid storage, and elevated triglyceride and lipid catabolism resulted in disruption of cell volume homeostasis and activated innate immune response, thus inhibiting melanoma development and progression. These data revealed a novel molecular mechanism involved in the antitumor effect of TFP via lipid metabolism.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

View References

1 

Mizuta K, Matsubara T, Goto A, Addison WN, Nakatomi M, Matsuo K, Tada-Shigeyama Y, Yaginuma T, Honda H, Yoshioka I and Kokabu S: Plectin promotes tumor formation by B16 mouse melanoma cells via regulation of Rous sarcoma oncogene activity. BMC Cancer. 22:9362022. View Article : Google Scholar : PubMed/NCBI

2 

Wang E, Liu Y, Xu C and Liu J: Antiproliferative and proapoptotic activities of anthocyanin and anthocyanidin extracts from blueberry fruits on B16-F10 melanoma cells. Food Nutr Res. 61:13253082017. View Article : Google Scholar : PubMed/NCBI

3 

Emens LA, Ascierto PA, Darcy PK, Demaria S, Eggermont AMM, Redmond WL, Seliger B and Marincola FM: Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape. Eur J Cancer. 81:116–129. 2017. View Article : Google Scholar : PubMed/NCBI

4 

Navarro C, Ortega A, Santeliz R, Garrido B, Chacín M, Galban N, Vera I, De Sanctis JB and Bermúdez V: Metabolic reprogramming in cancer cells: Emerging molecular mechanisms and novel therapeutic approaches. Pharmaceutics. 14:13032022. View Article : Google Scholar : PubMed/NCBI

5 

Zhao Q, Lin X and Wang G: Targeting SREBP-1-mediated lipogenesis as potential strategies for cancer. Front Oncol. 12:9523712022. View Article : Google Scholar : PubMed/NCBI

6 

Li J, Shen H, Owens GK and Guo LW: SREBP1 regulates Lgals3 activation in response to cholesterol loading. Mol Ther Nucleic Acids. 28:892–909. 2022. View Article : Google Scholar : PubMed/NCBI

7 

Bindesboll C, Aas A, Ogmundsdottir MH, Pankiv S, Reine T, Zoncu R and Simonsen A: NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease. Sci Rep. 10:45282020. View Article : Google Scholar : PubMed/NCBI

8 

Luo H, Chen CY, Li X, Zhang X, Su CW, Liu Y, Cao T, Hao L, Wang M and Kang JX: Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids. Stem Cells. 39:1660–1670. 2021. View Article : Google Scholar : PubMed/NCBI

9 

Kitamura K, Erlangga JS, Tsukamoto S, Sakamoto Y, Mabashi-Asazuma H and Iida K: Daidzein promotes the expression of oxidative phosphorylation- and fatty acid oxidation-related genes via an estrogen-related receptor alpha pathway to decrease lipid accumulation in muscle cells. J Nutr Biochem. 77:1083152020. View Article : Google Scholar

10 

Hu B, Lin JZ, Yang XB and Sang XT: Aberrant lipid metabolism in hepatocellular carcinoma cells as well as immune microenvironment: A review. Cell Prolif. 53:e127722020. View Article : Google Scholar : PubMed/NCBI

11 

Simeone P, Tacconi S, Longo S, Lanuti P, Bravaccini S, Pirini F, Ravaioli S, Dini L and Giudetti AM: Expanding roles of de novo lipogenesis in breast cancer. Int J Environ Res Public Health. 18:35752021. View Article : Google Scholar : PubMed/NCBI

12 

Zhao S, Torres A, Henry RA, Trefely S, Wallace M, Lee JV, Carrer A, Sengupta A, Campbell SL, Kuo YM, et al: ATP-citrate lyase controls a glucose-to-acetate metabolic switch. Cell Rep. 17:1037–1052. 2016. View Article : Google Scholar : PubMed/NCBI

13 

Ramapriyan R, Caetano MS, Barsoumian HB, Mafra ACP, Zambalde EP, Menon H, Tsouko E, Welsh JW and Cortez MA: Altered cancer metabolism in mechanisms of immunotherapy resistance. Pharmacol Ther. 195:162–171. 2019. View Article : Google Scholar

14 

Welte MA: Expanding roles for lipid droplets. Curr Biol. 25:R470–R481. 2015. View Article : Google Scholar : PubMed/NCBI

15 

Todisco S, Santarsiero A, Convertini P, De Stefano G, Gilio M, Iacobazzi V and Infantino V: PPAR alpha as a metabolic modulator of the liver: Role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Biology (Basel). 11:7922022.PubMed/NCBI

16 

Thiam AR, Farese RV Jr and Walther TC: The biophysics and cell biology of lipid droplets. Nat Rev Mol Cell Biol. 14:775–786. 2013. View Article : Google Scholar : PubMed/NCBI

17 

Hashemi HF and Goodman JM: The life cycle of lipid droplets. Curr Opin Cell Biol. 33:119–124. 2015. View Article : Google Scholar : PubMed/NCBI

18 

Cartwright BR, Binns DD, Hilton CL, Han S, Gao Q and Goodman JM: Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology. Mol Biol Cell. 26:726–739. 2015. View Article : Google Scholar :

19 

Shen T, Duan C, Chen B, Li M, Ruan Y, Xu D, Shi D, Yu D, Li J and Wang C: Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1. Mol Med Rep. 16:1340–1346. 2017. View Article : Google Scholar : PubMed/NCBI

20 

Terrazas C, Oghumu S, Varikuti S, Martinez-Saucedo D, Beverley SM and Satoskar AR: Uncovering Leishmania-macrophage interplay using imaging flow cytometry. J Immunol Methods. 423:93–98. 2015. View Article : Google Scholar : PubMed/NCBI

21 

Lee YT, Lim SH, Lee B, Kang I and Yeo EJ: Compound C Inhibits B16-F1 tumor growth in a syngeneic mouse model via the blockage of cell cycle progression and angiogenesis. Cancers (Basel). 11:8232019. View Article : Google Scholar : PubMed/NCBI

22 

Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES and Mesirov JP: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 102:15545–15550. 2005. View Article : Google Scholar : PubMed/NCBI

23 

Steinbusch LK, Schwenk RW, Ouwens DM, Diamant M, Glatz JF and Luiken JJ: Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes. Cell Mol Life Sci. 68:2525–2538. 2011. View Article : Google Scholar : PubMed/NCBI

24 

Romanauska A and Kohler A: The inner nuclear membrane is a metabolically active territory that generates nuclear lipid droplets. Cell. 174:700–715.e718. 2018. View Article : Google Scholar : PubMed/NCBI

25 

Chiu CH, Chiu KC and Yang LC: Amelioration of obesity in mice fed a high-fat diet with uronic acid-rich polysaccharides derived from tremella fuciformis. Polymers (Basel). 14:15142022. View Article : Google Scholar : PubMed/NCBI

26 

Shao W and Espenshade PJ: Expanding roles for SREBP in metabolism. Cell Metab. 16:414–419. 2012. View Article : Google Scholar : PubMed/NCBI

27 

Guo D, Bell EH, Mischel P and Chakravarti A: Targeting SREBP-1-driven lipid metabolism to treat cancer. Curr Pharm Des. 20:2619–2626. 2014. View Article : Google Scholar :

28 

Queiroz EA, Fortes ZB, da Cunha MA, Barbosa AM, Khaper N and Dekker RF: Antiproliferative and pro-apoptotic effects of three fungal exocellular beta-glucans in MCF-7 breast cancer cells is mediated by oxidative stress, AMP-activated protein kinase (AMPK) and the Forkhead transcription factor, FOXO3a. Int J Biochem Cell Biol. 67:14–24. 2015. View Article : Google Scholar : PubMed/NCBI

29 

Kim I and He YY: Targeting the AMP-activated protein kinase for cancer prevention and therapy. Front Oncol. 3:1752013. View Article : Google Scholar : PubMed/NCBI

30 

Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JYJ, et al: AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice. Cell Metab. 13:376–388. 2011. View Article : Google Scholar : PubMed/NCBI

31 

Rigel J, Kishton, Carson E, Cohen S, Gerriets VA, Siska PJ, Macintyre AN, Goraksha-Hicks P, de Cubas AA, Liu T, et al: AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival. Cell Metab. 12:649–662. 2016.

32 

Jeon SM, Chandel NS and Hay N: AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress. Nature. 485:661–665. 2012. View Article : Google Scholar : PubMed/NCBI

33 

Flori E, Rosati E, Cardinali G, Kovacs D, Bellei B, Picardo M and Maresca V: The α-melanocyte stimulating hormone/peroxisome proliferator activated receptor-γ pathway down-regulates proliferation in melanoma cell lines. J Exp Clin Cancer Res. 36:1422017. View Article : Google Scholar

34 

Cheng C, Geng F, Cheng X and Guo D: Lipid metabolism reprogramming and its potential targets in cancer. Cancer Commun (Lond). 38:272018. View Article : Google Scholar : PubMed/NCBI

35 

Wu Q, Li B, Li Z, Li J and Sun S and Sun S: Cancer-associated adipocytes: Key players in breast cancer progression. J Hematol Oncol. 12:952019. View Article : Google Scholar : PubMed/NCBI

36 

Martin P: Cancer cachexia syndrome: Reflecting on 20 years of providing cancer cachexia care as the leader of an interdisciplinary team in an Australian cancer center. Asia Pac J Oncol Nurs. 9:1000702022. View Article : Google Scholar : PubMed/NCBI

37 

Ryan DG, Murphy MP, Frezza C, Prag HA, Chouchani ET, O'Neill LA and Mills EL: Coupling Krebs cycle metabolites to signalling in immunity and cancer. Nat Metab. 1:16–33. 2019. View Article : Google Scholar : PubMed/NCBI

38 

Bartolacci C, Andreani C, Vale G, Berto S, Melegari M, Crouch AC, Baluya DL, Kemble G, Hodges K, Starrett J, et al: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer. Nat Commun. 13:43272022. View Article : Google Scholar : PubMed/NCBI

39 

Li L, Che L, Tharp KM, Park HM, Pilo MG, Cao D, Cigliano A, Latte G, Xu Z, Ribback S, et al: Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans. Hepatology. 63:1900–1913. 2016. View Article : Google Scholar : PubMed/NCBI

40 

Zaidi N, Lupien L, Kuemmerle NB, Kinlaw WB, Swinnen JV and Smans K: Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids. Prog Lipid Res. 52:585–589. 2013. View Article : Google Scholar : PubMed/NCBI

41 

Rizzo AM, Colombo I, Montorfano G, Zava S and Corsetto PA: Exogenous fatty acids modulate ER lipid composition and metabolism in breast cancer cells. Cells. 10:1752021. View Article : Google Scholar : PubMed/NCBI

42 

Dondossola E, Dobroff AS, Marchio S, Cardó-Vila M, Hosoya H, Libutti SK, Corti A, Sidman RL, Arap W and Pasqualini R: Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors. Proc Natl Acad Sci USA. 113:2223–2228. 2016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li X, Su Q and Pan Y: Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide. Int J Oncol 62: 11, 2023.
APA
Li, X., Su, Q., & Pan, Y. (2023). Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide. International Journal of Oncology, 62, 11. https://doi.org/10.3892/ijo.2022.5459
MLA
Li, X., Su, Q., Pan, Y."Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide". International Journal of Oncology 62.1 (2023): 11.
Chicago
Li, X., Su, Q., Pan, Y."Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide". International Journal of Oncology 62, no. 1 (2023): 11. https://doi.org/10.3892/ijo.2022.5459
Copy and paste a formatted citation
x
Spandidos Publications style
Li X, Su Q and Pan Y: Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide. Int J Oncol 62: 11, 2023.
APA
Li, X., Su, Q., & Pan, Y. (2023). Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide. International Journal of Oncology, 62, 11. https://doi.org/10.3892/ijo.2022.5459
MLA
Li, X., Su, Q., Pan, Y."Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide". International Journal of Oncology 62.1 (2023): 11.
Chicago
Li, X., Su, Q., Pan, Y."Overcharged lipid metabolism in mechanisms of antitumor by <em>Tremella fuciformis</em>‑derived polysaccharide". International Journal of Oncology 62, no. 1 (2023): 11. https://doi.org/10.3892/ijo.2022.5459
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team