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Long non‑coding RNAs in multiple myeloma (Review)

  • Authors:
    • Chenbo Yang
    • Yinghao Liang
    • Jiao Shu
    • Shuaiyuan Wang
    • Yichen Hong
    • Kuisheng Chen
    • Miaomiao Sun
  • View Affiliations / Copyright

    Affiliations: Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China, Henan Key Laboratory of Tumor Pathology, Zhengzhou University, Zhengzhou, Henan 450052, P.R. China
    Copyright: © Yang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Article Number: 69
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    Published online on: May 4, 2023
       https://doi.org/10.3892/ijo.2023.5517
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Abstract

Multiple myeloma (MM) is one of the three major malignancies of the hematological system in middle‑aged and older individuals. The incidence of MM increases with age and due to its drug resistance and high recurrence, MM seriously harms human health. Long non‑coding RNAs (lncRNAs) are RNA molecules with a length of >200 nt and rarely encode proteins. Numerous studies reported that lncRNAs regulate carcinogenesis and cancer progression. MM‑associated lncRNAs affect features of tumor cells, including proliferation, apoptosis, adhesion and treatment resistance. The present review aims to summarize the latest findings on the roles of lncRNAs in MM to deepen the understanding of this field and provide insight for developing specific diagnostic tools and effective treatment strategies for MM, including novel biomarkers and targeted lncRNA therapeutics.
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Copy and paste a formatted citation
Spandidos Publications style
Yang C, Liang Y, Shu J, Wang S, Hong Y, Chen K and Sun M: Long non‑coding RNAs in multiple myeloma (Review). Int J Oncol 62: 69, 2023.
APA
Yang, C., Liang, Y., Shu, J., Wang, S., Hong, Y., Chen, K., & Sun, M. (2023). Long non‑coding RNAs in multiple myeloma (Review). International Journal of Oncology, 62, 69. https://doi.org/10.3892/ijo.2023.5517
MLA
Yang, C., Liang, Y., Shu, J., Wang, S., Hong, Y., Chen, K., Sun, M."Long non‑coding RNAs in multiple myeloma (Review)". International Journal of Oncology 62.6 (2023): 69.
Chicago
Yang, C., Liang, Y., Shu, J., Wang, S., Hong, Y., Chen, K., Sun, M."Long non‑coding RNAs in multiple myeloma (Review)". International Journal of Oncology 62, no. 6 (2023): 69. https://doi.org/10.3892/ijo.2023.5517
Copy and paste a formatted citation
x
Spandidos Publications style
Yang C, Liang Y, Shu J, Wang S, Hong Y, Chen K and Sun M: Long non‑coding RNAs in multiple myeloma (Review). Int J Oncol 62: 69, 2023.
APA
Yang, C., Liang, Y., Shu, J., Wang, S., Hong, Y., Chen, K., & Sun, M. (2023). Long non‑coding RNAs in multiple myeloma (Review). International Journal of Oncology, 62, 69. https://doi.org/10.3892/ijo.2023.5517
MLA
Yang, C., Liang, Y., Shu, J., Wang, S., Hong, Y., Chen, K., Sun, M."Long non‑coding RNAs in multiple myeloma (Review)". International Journal of Oncology 62.6 (2023): 69.
Chicago
Yang, C., Liang, Y., Shu, J., Wang, S., Hong, Y., Chen, K., Sun, M."Long non‑coding RNAs in multiple myeloma (Review)". International Journal of Oncology 62, no. 6 (2023): 69. https://doi.org/10.3892/ijo.2023.5517
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