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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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September-2025 Volume 67 Issue 3

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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Correction Open Access

[Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer

  • Authors:
    • Lei Yan
    • Jing Zhang
    • Dong Guo
    • Ji Ma
    • Shao-Feng Shui
    • Xin-Wei Han
  • View Affiliations / Copyright

    Affiliations: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China, Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China
    Copyright: © Yan et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
  • Article Number: 74
    |
    Published online on: July 28, 2025
       https://doi.org/10.3892/ijo.2025.5780
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Article

View Figures

Figure 1

Knockdown of IL-21R suppresses cell
proliferation and invasion. (A) RT-qPCR and western blot analysis
of the knockdown efficiency following transfection with siIL-21R
for 48 h in the HGC-27 and MKN-45 cell lines. (B) CCK-8 assay was
used to detect the effects of IL-21R knockdown on cell
proliferative activities. (C and D) Transwell invasion assay was
conducted to assess the effects of IL-2R knockdown on the invasive
potential of gastric cancer (GC) cells. **P<0.01 vs.
NC.

Figure 2

IL-21R overexpression reverses the
tumor suppressive effects of miR-34a on gastric cancer (GC) cells.
(A) Cell proliferative activities were evaluated by CCK-8 assay in
the HGC-27 and MKN-45 cell lines following transfection with
Lv-IL-21R and/or miR-125a mimic. (B-D) Cell invasive potential was
assessed by Transwell invasion assay in the HGC-27 and MKN-45 cell
lines following transfection with Lv-IL-21R and/or miR-125a mimic.
(E and F) In vivo animal experiments for the validation of
the effects of IL-21R overexpression on the antitumor effects of
miR-125a. *P<0.05 and **P<0.01..

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Copy and paste a formatted citation
Spandidos Publications style
Yan L, Zhang J, Guo D, Ma J, Shui S and Han X: [Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer. Int J Oncol 67: 74, 2025.
APA
Yan, L., Zhang, J., Guo, D., Ma, J., Shui, S., & Han, X. (2025). [Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer. International Journal of Oncology, 67, 74. https://doi.org/10.3892/ijo.2025.5780
MLA
Yan, L., Zhang, J., Guo, D., Ma, J., Shui, S., Han, X."[Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer". International Journal of Oncology 67.3 (2025): 74.
Chicago
Yan, L., Zhang, J., Guo, D., Ma, J., Shui, S., Han, X."[Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer". International Journal of Oncology 67, no. 3 (2025): 74. https://doi.org/10.3892/ijo.2025.5780
Copy and paste a formatted citation
x
Spandidos Publications style
Yan L, Zhang J, Guo D, Ma J, Shui S and Han X: [Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer. Int J Oncol 67: 74, 2025.
APA
Yan, L., Zhang, J., Guo, D., Ma, J., Shui, S., & Han, X. (2025). [Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer. International Journal of Oncology, 67, 74. https://doi.org/10.3892/ijo.2025.5780
MLA
Yan, L., Zhang, J., Guo, D., Ma, J., Shui, S., Han, X."[Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer". International Journal of Oncology 67.3 (2025): 74.
Chicago
Yan, L., Zhang, J., Guo, D., Ma, J., Shui, S., Han, X."[Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in gastric cancer". International Journal of Oncology 67, no. 3 (2025): 74. https://doi.org/10.3892/ijo.2025.5780
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