|
1
|
Conti CB, Agnesi S, Scaravaglio M,
Masseria P, Dinelli ME, Oldani M and Uggeri F: Early gastric
cancer: Update on prevention, diagnosis and treatment. Int J
Environ Res Public Health. 20:21492023. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Rocken C: Predictive biomarkers in gastric
cancer. J Cancer Res Clin Oncol. 149:467–481. 2023. View Article : Google Scholar :
|
|
3
|
Smyth EC, Nilsson M, Grabsch HI, Van
Grieken NC and Lordick F: Gastric cancer. Lancet. 396:635–648.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Drizlionoks E, Tercioti V Junior, Coelho
Neto JS, Andreollo NA and Lopes LR: Surgical treatment of gastric
stump cancer: A cohort study of 51 patients. Arq Bras Cir Dig.
37:e18502025. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yang WJ, Zhao HP, Yu Y, Wang JH, Guo L,
Liu JY, Pu J and Lv J: Updates on global epidemiology, risk and
prognostic factors of gastric cancer. World J Gastroenterol.
29:2452–2468. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Qiu H, Cao S and Xu R: Cancer incidence,
mortality, and burden in China: A time-trend analysis and
comparison with the United States and United Kingdom based on the
global epidemiological data released in 2020. Cancer Commun (Lond).
41:1037–1048. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Veitch AM, Uedo N, Yao K and East JE:
Optimizing early upper gastrointestinal cancer detection at
endoscopy. Nat Rev Gastroenterol Hepatol. 12:660–667. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Haggstrom L, Chan WY, Nagrial A, Chantrill
LA, Sim HW, Yip D and Chin V: Chemotherapy and radiotherapy for
advanced pancreatic cancer. Cochrane Database Syst Rev.
12:CD0110442024.PubMed/NCBI
|
|
9
|
Gao S, Wang Y, Shan Y, Wang W, Li J and
Tan H: Rhizoma Coptidis polysaccharides: Extraction, separation,
purification, structural characteristics and bioactivities. Int J
Biol Macromol. 320(Pt 1): 1456772025. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Gao S, Xu T, Wang W, Li J, Shan Y, Wang Y
and Tan H: Polysaccharides from Anemarrhena asphodeloides Bge, the
extraction, purification, structure characterization, biological
activities and application of a traditional herbal medicine. Int J
Biol Macromol. 311(Pt 1): 1434972025. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Kavyashree S, Harithpriya K and Ramkumar
KM: Miro1-a key player in β-cell function and mitochondrial
dynamics under diabetes mellitus. Mitochondrion. 84:1020392025.
View Article : Google Scholar
|
|
12
|
Li JM, Li X, Chan LWC, Hu R, Zheng T, Li H
and Yang S: Lipotoxicity-polarised macrophage-derived exosomes
regulate mitochondrial fitness through Miro1-mediated mitophagy
inhibition and contribute to type 2 diabetes development in mice.
Diabetologia. 66:2368–2386. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Jeong YY, Jia N, Ganesan D and Cai Q:
Broad activation of the PRKN pathway triggers synaptic failure by
disrupting synaptic mitochondrial supply in early tauopathy.
Autophagy. 18:1472–1474. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Maremanda KP, Sundar IK and Rahman I:
Protective role of mesenchymal stem cells and mesenchymal stem
cell-derived exosomes in cigarette smoke-induced mitochondrial
dysfunction in mice. Toxicol Appl Pharmacol. 385:1147882019.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Li D, Su H, Deng X, Huang Y, Wang Z, Zhang
J, Chen C, Zheng Z, Wang Q, Zhao S, et al: DARS2 promotes bladder
cancer progression by enhancing PINK1-mediated mitophagy. Int J
Biol Sci. 21:1530–1544. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Deng X, Huang Y, Zhang J, Chen Y, Jiang F,
Zhang Z, Li T, Hou L, Tan W and Li F: Histone lactylation regulates
PRKN-Mediated mitophagy to promote M2 Macrophage polarization in
bladder cancer. Int Immunopharmacol. 148:1141192025. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Wang Z, Yu C, Xie G, Tao K, Yin Z and Lv
Q: USP14 inhibits mitophagy and promotes tumorigenesis and
chemosensitivity through deubiquitinating BAG4 in microsatellite
instability-high colorectal cancer. Mol Med. 31:1632025. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Zheng B, Wang Y, Zhou B, Qian F, Liu D, Ye
D, Zhou X and Fang L: Urolithin A inhibits breast cancer
progression via activating TFEB-mediated mitophagy in tumor
macrophages. J Adv Res. 69:125–138. 2025. View Article : Google Scholar :
|
|
19
|
Zheng S, Zhang Y, Gong X, Teng Z and Chen
J: CREB1 regulates RECQL4 to inhibit mitophagy and promote
esophageal cancer metastasis. J Clin Biochem Nutr. 75:102–110.
2024. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Chemla A, Arena G, Sacripanti G, Barmpa K,
Zagare A, Garcia P, Gorgogietas V, Antony P, Ohnmacht J, Baron A,
et al: Parkinson's disease mutant Miro1 causes mitochondrial
dysfunction and dopaminergic neuron loss. Brain. Feb 6–2025.Epub
ahead of print. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Cavinato M: Mitochondrial dysfunction and
cisplatin sensitivity in gastric cancer: GDF15 as a master player.
FEBS J. 291:1111–1114. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lo YL, Wang TY, Chen CJ, Chang YH and Lin
AM: Two-in-one nanoparticle formulation to deliver a tyrosine
kinase inhibitor and microRNA for targeting metabolic reprogramming
and mitochondrial dysfunction in gastric cancer. Pharmaceutics.
14:17592022. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Chen W, Zou P, Zhao Z, Weng Q, Chen X,
Ying S, Ye Q, Wang Z, Ji J and Liang G: Selective killing of
gastric cancer cells by a small molecule via targeting TrxR1 and
ROS-mediated ER stress activation. Oncotarget. 7:16593–16609. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Rong Y, Teng Y and Zhou X: Advances in the
study of metabolic reprogramming in gastric cancer. Cancer Med.
14:e709482025. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Peng YY, Sun D and Xin Y: Hsa_circ_0005230
is up-regulated and promotes gastric cancer cell invasion and
migration via regulating the miR-1299/RHOT1 axis. Bioengineered.
13:5046–5063. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
27
|
Li M, Pi H, Yang Z, Reiter RJ, Xu S, Chen
X, Chen C, Zhang L, Yang M, Li Y, et al: Melatonin antagonizes
cadmium-induced neurotoxicity by activating the transcription
factor EB-dependent autophagy-lysosome machinery in mouse
neuroblastoma cells. J Pineal Res. 61:353–369. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Procaccio L, Schirripa M, Fassan M,
Vecchione L, Bergamo F, Prete AA, Intini R, Manai C, Dadduzio V,
Boscolo A, et al: Immunotherapy in gastrointestinal cancers. Biomed
Res Int. 2017:43465762017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Leites EP and Morais VA: Mitochondrial
quality control pathways: PINK1 acts as a gatekeeper. Biochem
Biophys Res Commun. 500:45–50. 2018. View Article : Google Scholar
|
|
30
|
Yao RQ, Ren C, Xia ZF and Yao YM:
Organelle-specific autophagy in inflammatory diseases: A potential
therapeutic target underlying the quality control of multiple
organelles. Autophagy. 17:385–401. 2021. View Article : Google Scholar :
|
|
31
|
Wang Z, Chen C, Ai J, Shu J, Ding Y, Wang
W, Gao Y, Jia Y and Qin Y: Identifying mitophagy-related genes as
prognostic biomarkers and therapeutic targets of gastric carcinoma
by integrated analysis of single-cell and bulk-RNA sequencing data.
Comput Biol Med. 163:1072272023. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Eberhardt EL, Ludlam AV, Tan Z and
Cianfrocco MA: Miro: A molecular switch at the center of
mitochondrial regulation. Protein Sci. 29:1269–1284. 2020.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lopez-Domenech G, Howden JH, Covill-Cooke
C, Morfill C, Patel JV, Burli R, Crowther D, Birsa N, Brandon NJ
and Kittler JT: Loss of neuronal Miro1 disrupts mitophagy and
induces hyperactivation of the integrated stress response. EMBO J.
40:e1007152021. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Diaz-Moreno I and De La Rosa MA: IUBMB
focused meeting/FEBS workshop: Crosstalk between nucleus and
mitochondria in human disease (CrossMitoNus). IUBMB Life.
73:489–491. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Grossmann D, Berenguer-Escuder C, Chemla
A, Arena G and Kruger R: The Emerging role of RHOT1/Miro1 in the
pathogenesis of parkinson's disease. Front Neurol. 11:5872020.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Jiang H, He C, Geng S, Sheng H, Shen X,
Zhang X, Li H, Zhu S, Chen X, Yang C and Gao H: RhoT1 and Smad4 are
correlated with lymph node metastasis and overall survival in
pancreatic cancer. PLoS One. 7:e422342012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Li Q, Yao L, Wei Y, Geng S, He C and Jiang
H: Role of RHOT1 on migration and proliferation of pancreatic
cancer. Am J Cancer Res. 5:1460–1470. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Lopez-Domenech G, Higgs NF, Vaccaro V, Ros
H, Arancibia-Carcamo IL, Macaskill AF and Kittler JT: Loss of
dendritic complexity precedes neurodegeneration in a mouse model
with disrupted mitochondrial distribution in mature dendrites. Cell
Rep. 17:317–327. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Singh F, Prescott AR, Rosewell P, Ball G,
Reith AD and Ganley IG: Pharmacological rescue of impaired
mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in
mice. Elife. 10:e676042021. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Cao Y, Zheng J, Wan H, Sun Y, Fu S, Liu S,
He B, Cai G, Cao Y, Huang H, et al: A mitochondrial SCF-FBXL4
ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain
mitophagy and prevent mitochondrial disease. EMBO J.
42:e1130332023. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Lu Y, Li Z, Zhang S, Zhang T, Liu Y and
Zhang L: Cellular mitophagy: Mechanism, roles in diseases and small
molecule pharmacological regulation. Theranostics. 13:736–766.
2023. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Lemasters JJ: Selective mitochondrial
autophagy, or mitophagy, as a targeted defense against oxidative
stress, mitochondrial dysfunction, and aging. Rejuvenation Res.
8:3–5. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Covill-Cooke C, Toncheva VS, Drew J, Birsa
N, Lopez-Domenech G and Kittler JT: Peroxisomal fission is
modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2. EMBO
Rep. 21:e498652020. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Costello JL, Castro IG, Camoes F, Schrader
TA, Mcneall D, Yang J, Giannopoulou EA, Gomes S, Pogenberg V,
Bonekamp NA, et al: Predicting the targeting of tail-anchored
proteins to subcellular compartments in mammalian cells. J Cell
Sci. 130:1675–1687. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Raiff A, Zhao S, Bekturova A, Zenge C,
Mazor S, Chen X, Ru W, Makaros Y, Ast T, Ordureau A, et al:
TOM20-driven E3 ligase recruitment regulates mitochondrial dynamics
through PLD6. Nat Chem Biol. Apr 22–2025.Epub ahead of print.
View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Saleem A, Iqbal S, Zhang Y and Hood DA:
Effect of p53 on mitochondrial morphology, import, and assembly in
skeletal muscle. Am J Physiol Cell Physiol. 308:C319–C329. 2015.
View Article : Google Scholar :
|
|
47
|
Zha J, Li J, Yin H, Shen M and Xia Y:
TIMM23 overexpression drives NSCLC cell growth and survival by
enhancing mitochondrial function. Cell Death Dis. 16:1742025.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Kumar N, Shukla A, Kumar S, Ulasov I,
Singh RK, Kumar S, Patel A, Yadav L, Tiwari R, Paswan R, et al: FNC
(4'-azido-2'-deoxy-2'-fluoro(arbino)cytidine) as an effective
therapeutic agent for NHL: ROS generation, cell cycle arrest, and
mitochondrial-mediated apoptosis. Cell Biochem Biophys. 82:623–639.
2024. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Tian X, Yuan M, Li L, Chen D, Liu B, Zou
X, He M and Wu Z: Enterovirus 71 induces mitophagy via PINK1/Parkin
signaling pathway to promote viral replication. FASEB J.
39:e706592025. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Lu J, Zhang Y, Song H, Wang F, Wang L,
Xiong L and Shen X: A novel polysaccharide from tremella fuciformis
alleviated high-fat diet-induced obesity by promoting
AMPK/PINK1/PRKN-Mediated mitophagy in mice. Mol Nutr Food Res.
69:e2024006992025. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Bai LY, Su JH, Chiu CF, Lin WY, Hu JL,
Feng CH, Shu CW and Weng JR: Antitumor effects of a sesquiterpene
derivative from marine sponge in human breast cancer cells. Mar
Drugs. 19:2442021. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Bhavya K, Mantipally M, Roy S, Arora L,
Badavath VN, Gangireddy M, Dasgupta S, Gundla R and Pal D: Novel
imidazo[1,2-a]pyridine derivatives induce apoptosis and cell cycle
arrest in non-small cell lung cancer by activating NADPH oxidase
mediated oxidative stress. Life Sci. 294:1203342022. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Minella AC, Swanger J, Bryant E, Welcker
M, Hwang H and Clurman BE: p53 and p21 form an inducible barrier
that protects cells against cyclin E-cdk2 deregulation. Curr Biol.
12:1817–1827. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Yu C, Sun J, Lai X, Tan Z, Wang Y, Du H,
Pan Z, Chen T, Yang Z, Ye S, et al: Gefitinib induces apoptosis in
Caco-2 cells via ER stress-mediated mitochondrial pathways and the
IRE1alpha/JNK/p38 MAPK signaling axis. Med Oncol. 42:712025.
View Article : Google Scholar
|
|
55
|
Guefack MF, Talukdar D, Mukherjee R, Guha
S, Mitra D, Saha D, Das G, Damen F, Kuete V and Murmu N: Hypericum
roeperianum bark extract suppresses breast cancer proliferation via
induction of apoptosis, downregulation of PI3K/Akt/mTOR signaling
cascade and reversal of EMT. J Ethnopharmacol. 319(Pt 1):
1170932024. View Article : Google Scholar
|
|
56
|
Huang J, Zhang Y, Cheng A, Wang M, Liu M,
Zhu D, Chen S, Zhao X, Yang Q, Wu Y, et al: Duck Circovirus
genotype 2 ORF3 protein induces apoptosis through the mitochondrial
pathway. Poult Sci. 102:1025332023. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Peng J, Yang Z, Li H, Hao B, Cui D, Shang
R, Lv Y, Liu Y, Pu W, Zhang H, et al: Quercetin reprograms
immunometabolism of macrophages via the SIRT1/PGC-1alpha signaling
pathway to ameliorate lipopolysaccharide-induced oxidative damage.
Int J Mol Sci. 24:55422023. View Article : Google Scholar
|
|
58
|
Chen JT, Wei L, Chen TL, Huang CJ and Chen
RM: Regulation of cytochrome P450 gene expression by ketamine: A
review. Expert Opin Drug Metab Toxicol. 14:709–720. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
59
|
Qin W, Li C, Zheng W, Guo Q, Zhang Y, Kang
M, Zhang B, Yang B, Li B, Yang H and Wu Y: Inhibition of autophagy
promotes metastasis and glycolysis by inducing ROS in gastric
cancer cells. Oncotarget. 6:39839–39854. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Agarwal E, Altman BJ, Ho Seo J, Bertolini
I, Ghosh JC, Kaur A, Kossenkov AV, Languino LR, Gabrilovich DI,
Speicher DW, et al: Myc regulation of a mitochondrial trafficking
network mediates tumor cell invasion and metastasis. Mol Cell Biol.
39:e00109–19. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Panigrahi DP, Praharaj PP, Bhol CS,
Mahapatra KK, Patra S, Behera BP, Mishra SR and Bhutia SK: The
emerging, multifaceted role of mitophagy in cancer and cancer
therapeutics. Semin Cancer Biol. 66:45–58. 2020. View Article : Google Scholar
|
