[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Tentori,Lucio; Leonetti,Carlo; Muzi,Alessia; Dorio,Annalisa Susanna; Porru,Manuela; Dolci,Susanna; Campolo,Federica; Vernole,Patrizia; Lacal,Pedro Miguel; Praz,Françoise; Graziani,Grazia

doi:10.3892/ijo.2026.5868

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Authors:
- Lucio Tentori
- Carlo Leonetti
- Alessia Muzi
- Annalisa Susanna Dorio
- Manuela Porru
- Susanna Dolci
- Federica Campolo
- Patrizia Vernole
- Pedro Miguel Lacal
- Françoise Praz
- Grazia Graziani
View Affiliations / Copyright

Affiliations: Department of System Medicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy, Experimental Preclinical Laboratory, Regina Elena National Cancer Institute, I-00158 Rome, Italy, Department of Biomedicine, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy, Department of Science and Technology of Education, University of Rome ‘Tor Vergata’, I-00133 Rome, Italy, Laboratory of Molecular Oncology, Istituto Dermopatico Dell'Immacolata (IDI), Istituto di Recovero e Cura a Carattere Scientifico (IRCCS)’, I-00167 Rome, Italy, INSERM, UMR_S 938, Saint-Antoine Research Centre, F-75012 Paris, France

Copyright: © Tentori et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].
Article Number: 55
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Published online on: March 9, 2026

https://doi.org/10.3892/ijo.2026.5868
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Int J Oncol 43: [Related article:] 210-218, 2013; DOI: 10.3892/ijo.2013.1932

Following the publication of the above article, an interested reader drew to the attention of the Editorial Office that the immunofluorescence images shown in Fig. 3B on p. 214 to represent the 'HCT116 SiP' and 'HCT116+3 SiP' experiments (top row of data) were strikingly similar.

Figure 3

Analysis of DNA damage induced by SN-38 in HCT116 or HCT116+3 cells control or stably silenced for PARP-1 expression. (A) Immunoblot analysis of γ-H2AX expression in SN-38 treated cells. Cells were treated with SN-38 (1.2 and 2.5 nM) for 24 h and analysed for the expression of γ-H2AX or tubulin. Histograms represent the ratios between the OD of γ-H2AX in SN-38 treated groups and tubulin. The results are representative of one out of two experiments with similar results. (B) Immunofluorescence analysis of γ-H2AX foci (green) in untreated or SN-38 treated cells. Nuclei were stained with DAPI (blue). The percentage of cells with ≥5 γ-H2AX foci of one representative out of two experiments is presented (50 cells counted for each experiment).

Upon examining their data, the authors have realized that the data in Fig. 3B were presented incorrectly; specifically, the data shown in the 'HCT116+3 SiP' panel were erroneously duplicated from the data shown correctly in the 'HCT116 SiP' panel.

The authors have now submitted a revised version of Fig. 3, containing the corrected version of the 'HCT116+3 SiP' data panel in Fig. 3B, and this is shown on the next page. Note that this error did not affect the overall conclusions reported in the study. The authors are grateful to the Editor of International Journal of Oncology for allowing them this opportunity to publish a Corrigendum, and all the authors agree with its publication. Furthermore, the authors apologize to the readership for any inconvenience caused.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

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