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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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January 2003 Volume 22 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January 2003 Volume 22 Issue 1

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Article

Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array

  • Authors:
    • Toshio Kokuryo
    • Tatsuyoshi Yamamoto
    • Koji Oda
    • Junichi Kamiya
    • Yuji Nimura
    • Takeshi Senga
    • Yoshinari Yasuda
    • Yoshiyuki Ohno
    • Yasuni Nakanuma
    • Miin-Fu Chen
    • Yi-Yin Jan
    • Ta-Sen Yeh
    • Cheng-Taug Chiu
    • Ling-Ling Hsieh
    • Michinari Hamaguchi

  • View Affiliations / Copyright

    Affiliations: Division of Surgical Oncology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan
  • Pages: 175-179
    |
    Published online on: January 1, 2003
       https://doi.org/10.3892/ijo.22.1.175
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Abstract

By use of cDNA expression array method, we compared the expression profiles of genes in hepatolithiasis tissues with those of paired normal tissues. Expression of 1176 cancer related genes that include 33 tumor suppressor genes, 100 proto-oncogenes and 37 DNA damage repair genes were examined in this study. We found that expression of tumor suppressor genes and proto-oncogenes was systemically activated in hepatholithiasis tissues, suggesting that expression of genes controlling cell growth becomes unstable in liver lobe of hepatolithiasis. In contrast, expression of DNA damage repair genes were not activated but rather remained unchanged in hepatholithiasis tissues, suggesting that repair process is not strongly activated but rather impaired in hepatholithiasis tissues.

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Copy and paste a formatted citation
Spandidos Publications style
Kokuryo T, Yamamoto T, Oda K, Kamiya J, Nimura Y, Senga T, Yasuda Y, Ohno Y, Nakanuma Y, Chen M, Chen M, et al: Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array. Int J Oncol 22: 175-179, 2003.
APA
Kokuryo, T., Yamamoto, T., Oda, K., Kamiya, J., Nimura, Y., Senga, T. ... Hamaguchi, M. (2003). Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array. International Journal of Oncology, 22, 175-179. https://doi.org/10.3892/ijo.22.1.175
MLA
Kokuryo, T., Yamamoto, T., Oda, K., Kamiya, J., Nimura, Y., Senga, T., Yasuda, Y., Ohno, Y., Nakanuma, Y., Chen, M., Jan, Y., Yeh, T., Chiu, C., Hsieh, L., Hamaguchi, M."Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array". International Journal of Oncology 22.1 (2003): 175-179.
Chicago
Kokuryo, T., Yamamoto, T., Oda, K., Kamiya, J., Nimura, Y., Senga, T., Yasuda, Y., Ohno, Y., Nakanuma, Y., Chen, M., Jan, Y., Yeh, T., Chiu, C., Hsieh, L., Hamaguchi, M."Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array". International Journal of Oncology 22, no. 1 (2003): 175-179. https://doi.org/10.3892/ijo.22.1.175
Copy and paste a formatted citation
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Spandidos Publications style
Kokuryo T, Yamamoto T, Oda K, Kamiya J, Nimura Y, Senga T, Yasuda Y, Ohno Y, Nakanuma Y, Chen M, Chen M, et al: Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array. Int J Oncol 22: 175-179, 2003.
APA
Kokuryo, T., Yamamoto, T., Oda, K., Kamiya, J., Nimura, Y., Senga, T. ... Hamaguchi, M. (2003). Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array. International Journal of Oncology, 22, 175-179. https://doi.org/10.3892/ijo.22.1.175
MLA
Kokuryo, T., Yamamoto, T., Oda, K., Kamiya, J., Nimura, Y., Senga, T., Yasuda, Y., Ohno, Y., Nakanuma, Y., Chen, M., Jan, Y., Yeh, T., Chiu, C., Hsieh, L., Hamaguchi, M."Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array". International Journal of Oncology 22.1 (2003): 175-179.
Chicago
Kokuryo, T., Yamamoto, T., Oda, K., Kamiya, J., Nimura, Y., Senga, T., Yasuda, Y., Ohno, Y., Nakanuma, Y., Chen, M., Jan, Y., Yeh, T., Chiu, C., Hsieh, L., Hamaguchi, M."Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array". International Journal of Oncology 22, no. 1 (2003): 175-179. https://doi.org/10.3892/ijo.22.1.175
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