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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2003 Volume 22 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Chemoprevention of prostate cancer by diet-derived antioxidant agents and hormonal manipulation (Review)

S. K. Pathak, R. A. Sharma, J. K. Mellon
Pages: 5-13
Published online on: 01 January 2003

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Review

Molecular signaling in death receptor and mitochondrial pathways of apoptosis (Review)

Sudhir Gupta
Pages: 15-20
Published online on: 01 January 2003

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Review

Cellular signaling pathways affect the function of ribonucleotide reductase mRNA binding proteins: mRNA stabilization, drug resistance, and malignancy (Review)

Teralee R. Burton, Tarek Kashour, Jim A. Wright, Francis M. Amara
Pages: 21-31
Published online on: 01 January 2003

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Article

Constitutive expression of cytotoxic proteases and down-regulation of protease inhibitors in LGL leukemia

Ravi Kothapalli, Ratna D. Bailey, Irina Kusmartseva, Shrikant Mane, P. K. Epling-Burnette, Thomas P. Loughran
Pages: 33-39
Published online on: 01 January 2003

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Article

Combined deficiency of hMLH1, hMSH2, hMSH3 and hMSH6 is an independent prognostic factor in colorectal cancer

Agneta Jansson, Gunnar Arbman, Hong Zhang, Xiao-Feng Sun
Pages: 41-49
Published online on: 01 January 2003

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Article

Role of p53 in G2/M cell cycle arrest and apoptosis in response to γ-irradiation in ovarian carcinoma cell lines

Nicole Concin, Margit Stimpfl, Christa Zeillinger, Uwe Wolff, Lukas Hefler, Jan Sedlak, Sepp Leodolter, Robert Zeillinger
Pages: 51-57
Published online on: 01 January 2003

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Article

Expression of the anti-apoptotic gene survivin in myelodysplastic syndrome

Adel Badran, Akira Yoshida, Yuji Wano, Masato Mutoh, Shin Imamura, Taro Yamashita, Hiroshi Tsutani, Manabu Inuzuka, Takanori Ueda
Pages: 59-64
Published online on: 01 January 2003

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Article

Genetic pathways of ‘de novo’ colorectal carcinomas with reference to fetal-type glycogen phosphorylase positive foci

Kenji Shiomori, Shinya Shimada, Takashi Marutsuka, Ichiro Hatayama, Michio Ogawa
Pages: 65-74
Published online on: 01 January 2003

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Article

Clinical significance of the expression of activin A in esophageal carcinoma

Keiji Yoshinaga, Koshi Mimori, Keishi Yamashita, Tohru Utsunomiya, Hiroshi Inoue, Masaki Mori
Pages: 75-80
Published online on: 01 January 2003

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Article

Restoration of p53 gene function in 12-O-tetradecanoylphorbor 13-acetate-resistant human leukemia K562/TPA cells

Jitsuo Usuda, Motoko Inomata, Hisao Fukumoto, Yasuo Iwamoto, Toshihiro Suzuki, Hyo-Jeong Kuh, Kazuya Fukuoka, Harubumi Kato, Nagahiro Saijo, Kazuto Nishio
Pages: 81-86
Published online on: 01 January 2003

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Article

Angiostatin inhibits extracellular HIV-Tat-induced inflammatory angiogenesis

Roberto Benelli, Monica Morini, Claudio Brigati, Douglas M. Noonan, Adriana Albini
Pages: 87-91
Published online on: 01 January 2003

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Article

A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo

Lori Holle, Wendy Song, Eric Holle, Yanzhang Wei, Thomas Wagner, Xianzhong Yu
Pages: 93-98
Published online on: 01 January 2003

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Article

Expression of cyclooxygenase-2 and its relationship to p53 accumulation in ovarian adenocarcinomas

Kazushi Shigemasa, Xiurong Tian, Lijun Gu, Yuko Shiroyama, Nobutaka Nagai, Koso Ohama
Pages: 99-105
Published online on: 01 January 2003

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Article

In vitro inhibition of growth and induction of apoptosis in cancer cell lines by thymoquinone

Ahmed M. Shoieb, Mona Elgayyar, Paul S. Dudrick, John L. Bell, Patricia K. Tithof
Pages: 107-113
Published online on: 01 January 2003

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Article

Apoptosis, proliferation, and hormone receptors in endometrial carcinoma: Results depending on methods of analysis

M. Dahmoun, T. Bäckström, K. Boman, S. Cajander
Pages: 115-122
Published online on: 01 January 2003

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Article

Determination of the in vivo effects of prednisone on Bcl-2 family protein expression in childhood acute lymphoblastic leukemia

F. Casale, R. Addeo, V. D'Angelo, P. Indolfi, V. Poggi, C. Morgera, S. Crisci, M. T. Di Tullio
Pages: 123-128
Published online on: 01 January 2003

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Article

Engagement of PI-3-kinase mediated Protein kinase C ζ activation in protecting Friend cells from ionizing radiation-induced apoptosis

Amelia Cataldi, Roberta Di Pietro, Lucia Centurione, Monica Rapino, Eugenio Santavenere, Francesco Garaci, Lucio Cocco, Gabriella Giuliani-Piccari, Rosalba Rana
Pages: 129-135
Published online on: 01 January 2003

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Article

Protein kinase C-α activation by phorbol ester induces secretion of gelatinase B/MMP-9 through ERK 1/2 pathway in capillary endothelial cells

Myung-Jin Park, In-Chul Park, Hyung-Chan Lee, Sang-Hyeok Woo, Jae-Young Lee, Young-Joon Hong, Chang-Hun Rhee, Yun-Sil Lee, Seung-Hoon Lee, Bum-Sang Shim, Toshino Kuroki, Seok-Il Hong
Pages: 137-143
Published online on: 01 January 2003

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Article

Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors

Prashant R. Nambiar, Geoff Girnun, Nicholas A. Lillo, Kishore Guda, Herbert E. Whiteley, Daniel W. Rosenberg
Pages: 145-150
Published online on: 01 January 2003

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Article

N-phenethyl-2-phenylacetamide isolated from Xenorhabdus nematophilus induces apoptosis through caspase activation and calpain-mediated Bax cleavage in U937 cells

Seok-Young Hwang, Seunguk Paik, Sun-Ho Park, Hyun-Su Kim, In-Seon Lee, Sang-Pyo Kim, Won-Ki Baek, Min-Ho Suh, Taeg Kyu Kwon, Jong-Wook Park, Jae-Bok Park, Jung-Jeung Lee, Seong-Il Suh
Pages: 151-157
Published online on: 01 January 2003

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Article

Quercetin regulates growth of Ishikawa cells through the suppression of EGF and cyclin D1

Masanori Kaneuchi, Masahiro Sasaki, Yuichiro Tanaka, Noriaki Sakuragi, Seiichiro Fujimoto, Rajvir Dahiya
Pages: 159-164
Published online on: 01 January 2003

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Article

Expression of angiogenic factors including VEGFs and the effects of hypoxia and thalidomide on human myeloma cells

Kenichiro Yata, Takemi Otsuki, Junichi Kurebayashi, Masako Uno, Tomohiro Fujii, Yoshihito Yawata, Akiko Takata, Fuminori Hyodoh, Takashi Sugihara
Pages: 165-173
Published online on: 01 January 2003

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Article

Profiling of gene expression associated with hepatolithiasis by complementary DNA expression array

Toshio Kokuryo, Tatsuyoshi Yamamoto, Koji Oda, Junichi Kamiya, Yuji Nimura, Takeshi Senga, Yoshinari Yasuda, Yoshiyuki Ohno, Yasuni Nakanuma, Miin-Fu Chen, Yi-Yin Jan, Ta-Sen Yeh, Cheng-Taug Chiu, Ling-Ling Hsieh, Michinari Hamaguchi
Pages: 175-179
Published online on: 01 January 2003

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Article

Bcl-2 in cancer and normal tissue cells as a prediction marker of response to 5-fluorouracil

Masao Sasaki, Tsutomu Kumazaki, Keiji Tanimoto, Masahiko Nishiyama
Pages: 181-186
Published online on: 01 January 2003

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Review

Simian virus 40 and malignant mesothelioma (Review)

Paolo Giuseppe Cerrano, Bharat Jasani, Rosangela Filiberti, Monica Neri, Franco Merlo, Silvio De Flora, Luciano Mutti, Riccardo Puntoni
Pages: 187-194
Published online on: 01 January 2003

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Article

Rap1 activity is elevated in malignant astrocytomas independent of tuberous sclerosis complex-2 gene expression

Nelson Lau, Erik J. Uhlmann, Friederike C. Von Lintig, Andras Nagy, Gerry R. Boss, David H. Gutmann, Abhijit Guha
Pages: 195-200
Published online on: 01 January 2003

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Article

Effect of gemcitabine and cis-platinum combinations on ribonucleotide and deoxyribonucleotide pools in ovarian cancer cell lines

C. J.A. Van Moorsel, K. Smid, D. A. Voorn, A. M. Bergman, H. M. Pinedo, G. J. Peters
Pages: 201-207
Published online on: 01 January 2003

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Article

Expression and regulation of WNT1 in human cancer: Up-regulation of WNT1 by β-estradiol in MCF-7 cells

Masaru Katoh
Pages: 209-212
Published online on: 01 January 2003

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Article

Determination of RNA expression for cholecystokinin/gastrin receptors (CCKA, CCKB and CCKC) in human tumors of the central and peripheral nervous system

Florence Lefranc, Carole Chaboteaux, Nathalie Belot, Jacques Brotchi, Isabelle Salmon, Robert Kiss
Pages: 213-219
Published online on: 01 January 2003

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Article

Risk estimation of radiation-incuced thyroid cancer from treatment of brain tumors in adults and children

M. Mazonakis, J. Damilakis, H. Varveris, M. Fasoulaki, N. Gourtsoyiannis
Pages: 221-225
Published online on: 01 January 2003

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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