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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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June 2003 Volume 22 Issue 6

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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June 2003 Volume 22 Issue 6

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Article

Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group

  • Authors:
    • Paolo A. Ascierto
    • Giuseppe Palmieri
    • Gerardo Botti
    • Rocco A. Satriano
    • Ignazio Stanganelli
    • Riccardo Bono
    • Alessandro Testori
    • Leonardo Bosco
    • Antonio Daponte
    • Corrado Caracò
    • Maria Grazia Chiofalo
    • Maria Teresa Melucci
    • Rosario Calignano
    • Fabiana Tatangelo
    • Alistair J. Cochran
    • Giuseppe Castello

  • View Affiliations / Copyright

    Affiliations: Unit of Clinical Immunology, National Tumor Institute ‘G. Pascale’, I-80131 Naples, Italy. pasciert@tin.it
  • Pages: 1209-1215
    |
    Published online on: June 1, 2003
       https://doi.org/10.3892/ijo.22.6.1209
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Abstract

Epiluminescence microscopy (ELM) strongly improves the separation of different types of cutaneous pigmented lesions (CPL) and facilitates the early diagnosis of cutaneous melanoma (CM). ELM alone is not 100% accurate in routine diagnosis, and should not be considered the only criterion in the diagnosis of high-risk skin lesions. We have however, demonstrated close agreement between ELM classification criteria and histology in 2,731 cutaneous lesions. In the past five years, our Melanoma Cooperative Group has evaluated 61,000 skin lesions from 30,000 individuals and identified 478 cutaneous melanomas. Most newly diagnosed patients had very early stage melanoma [299 (62%) were Stage I (203 Stage IA and 96 Stage IB), by the American Joint Committee on Cancer (AJCC) criteria]. We have compared data from the patient histories and clinical evaluations with ELM-based morphological patterns to better characterize skin lesions and minimize interpretative problems. From these comparisons, we propose new guidelines for the management of CPL to provide a standard diagnostic and therapeutic approaches and to foster the early identification of lesions at risk for malignant transformation.

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Copy and paste a formatted citation
Spandidos Publications style
Ascierto PA, Palmieri G, Botti G, Satriano RA, Stanganelli I, Bono R, Testori A, Bosco L, Daponte A, Caracò C, Caracò C, et al: Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group. Int J Oncol 22: 1209-1215, 2003.
APA
Ascierto, P.A., Palmieri, G., Botti, G., Satriano, R.A., Stanganelli, I., Bono, R. ... Castello, G. (2003). Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group. International Journal of Oncology, 22, 1209-1215. https://doi.org/10.3892/ijo.22.6.1209
MLA
Ascierto, P. A., Palmieri, G., Botti, G., Satriano, R. A., Stanganelli, I., Bono, R., Testori, A., Bosco, L., Daponte, A., Caracò, C., Chiofalo, M. G., Melucci, M. T., Calignano, R., Tatangelo, F., Cochran, A. J., Castello, G."Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group". International Journal of Oncology 22.6 (2003): 1209-1215.
Chicago
Ascierto, P. A., Palmieri, G., Botti, G., Satriano, R. A., Stanganelli, I., Bono, R., Testori, A., Bosco, L., Daponte, A., Caracò, C., Chiofalo, M. G., Melucci, M. T., Calignano, R., Tatangelo, F., Cochran, A. J., Castello, G."Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group". International Journal of Oncology 22, no. 6 (2003): 1209-1215. https://doi.org/10.3892/ijo.22.6.1209
Copy and paste a formatted citation
x
Spandidos Publications style
Ascierto PA, Palmieri G, Botti G, Satriano RA, Stanganelli I, Bono R, Testori A, Bosco L, Daponte A, Caracò C, Caracò C, et al: Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group. Int J Oncol 22: 1209-1215, 2003.
APA
Ascierto, P.A., Palmieri, G., Botti, G., Satriano, R.A., Stanganelli, I., Bono, R. ... Castello, G. (2003). Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group. International Journal of Oncology, 22, 1209-1215. https://doi.org/10.3892/ijo.22.6.1209
MLA
Ascierto, P. A., Palmieri, G., Botti, G., Satriano, R. A., Stanganelli, I., Bono, R., Testori, A., Bosco, L., Daponte, A., Caracò, C., Chiofalo, M. G., Melucci, M. T., Calignano, R., Tatangelo, F., Cochran, A. J., Castello, G."Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group". International Journal of Oncology 22.6 (2003): 1209-1215.
Chicago
Ascierto, P. A., Palmieri, G., Botti, G., Satriano, R. A., Stanganelli, I., Bono, R., Testori, A., Bosco, L., Daponte, A., Caracò, C., Chiofalo, M. G., Melucci, M. T., Calignano, R., Tatangelo, F., Cochran, A. J., Castello, G."Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group". International Journal of Oncology 22, no. 6 (2003): 1209-1215. https://doi.org/10.3892/ijo.22.6.1209
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