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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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February 2004 Volume 24 Issue 2

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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February 2004 Volume 24 Issue 2

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Article

Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients

  • Authors:
    • Hiroko Takedatsu
    • Shigeki Shichijo
    • Kouichi Azuma
    • Hidetoshi Takedatsu
    • Michio Sata
    • Kyogo Itoh

  • View Affiliations / Copyright

    Affiliations: Department of Immunology, Kurume University School of Medicine, Kurume, Japan
  • Pages: 337-347
    |
    Published online on: February 1, 2004
       https://doi.org/10.3892/ijo.24.2.337
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Abstract

The molecular basis of host-tumor interaction in HLA-A31+ cancer patients has not been well understood. This lack of clarification is hampering the development of specific immunotherapies for these patients. This study aimed to identify a set of CTL-epitope peptides applicable for the specific immunotherapy of cancer patients with HLA-A31 allele. HLA-A31 allele is expressed in 5-10% of the world population, with the highest expression among Brazilian Amerinds (65%), and the lowest in the Eskimo population (0%). We report herein four cDNAs encoding CTL-epitopes and 7 epitope peptides with the ability to induce HLA-A31-restricted CTLs cytotoxic to tumor cell lines in the peripheral blood mononuclear cells of HLA-A31+ cancer patients. These peptides might be useful for the development of a peptide-based immunotherapy for HLA-A31+ cancer patients.

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Copy and paste a formatted citation
Spandidos Publications style
Takedatsu H, Shichijo S, Azuma K, Takedatsu H, Sata M and Itoh K: Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients. Int J Oncol 24: 337-347, 2004.
APA
Takedatsu, H., Shichijo, S., Azuma, K., Takedatsu, H., Sata, M., & Itoh, K. (2004). Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients. International Journal of Oncology, 24, 337-347. https://doi.org/10.3892/ijo.24.2.337
MLA
Takedatsu, H., Shichijo, S., Azuma, K., Takedatsu, H., Sata, M., Itoh, K."Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients". International Journal of Oncology 24.2 (2004): 337-347.
Chicago
Takedatsu, H., Shichijo, S., Azuma, K., Takedatsu, H., Sata, M., Itoh, K."Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients". International Journal of Oncology 24, no. 2 (2004): 337-347. https://doi.org/10.3892/ijo.24.2.337
Copy and paste a formatted citation
x
Spandidos Publications style
Takedatsu H, Shichijo S, Azuma K, Takedatsu H, Sata M and Itoh K: Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients. Int J Oncol 24: 337-347, 2004.
APA
Takedatsu, H., Shichijo, S., Azuma, K., Takedatsu, H., Sata, M., & Itoh, K. (2004). Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients. International Journal of Oncology, 24, 337-347. https://doi.org/10.3892/ijo.24.2.337
MLA
Takedatsu, H., Shichijo, S., Azuma, K., Takedatsu, H., Sata, M., Itoh, K."Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients". International Journal of Oncology 24.2 (2004): 337-347.
Chicago
Takedatsu, H., Shichijo, S., Azuma, K., Takedatsu, H., Sata, M., Itoh, K."Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients". International Journal of Oncology 24, no. 2 (2004): 337-347. https://doi.org/10.3892/ijo.24.2.337
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