Basal and luminal breast cancers: Basic or luminous? (Review)

  • Authors:
    • Daniel Birnbaum
    • François Bertucci
    • Christophe Ginestier
    • Rebecca Tagett
    • Jocelyne Jacquemier
    • Emmanuelle Charafe-Jauffret
  • View Affiliations

  • Published online on: August 1, 2004     https://doi.org/10.3892/ijo.25.2.249
  • Pages: 249-258
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Abstract

Three major, fast developing lines of research are elucidating the biology of the mammary gland and its malignant transformation: phenotypical analyses of epithelial cells and mammary proliferative lesions, the identification, purification and characterization of mammary stem cells and breast cancer-initiating cells, and gene expression profiling studies using high-throughput microarray technologies. These three approaches are providing a flux of new, increasingly coherent information and are improving cellular and molecular models of breast epithelium and its malignancies. A new conceptual framework is emerging, altering viewpoints on the differentiation and transformation of the mammary epithelial cells. The combined effects of these progresses on our understanding of breast cancer biology should have major consequences on the way this disease is managed.

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August 2004
Volume 25 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Birnbaum D, Bertucci F, Ginestier C, Tagett R, Jacquemier J and Charafe-Jauffret E: Basal and luminal breast cancers: Basic or luminous? (Review). Int J Oncol 25: 249-258, 2004
APA
Birnbaum, D., Bertucci, F., Ginestier, C., Tagett, R., Jacquemier, J., & Charafe-Jauffret, E. (2004). Basal and luminal breast cancers: Basic or luminous? (Review). International Journal of Oncology, 25, 249-258. https://doi.org/10.3892/ijo.25.2.249
MLA
Birnbaum, D., Bertucci, F., Ginestier, C., Tagett, R., Jacquemier, J., Charafe-Jauffret, E."Basal and luminal breast cancers: Basic or luminous? (Review)". International Journal of Oncology 25.2 (2004): 249-258.
Chicago
Birnbaum, D., Bertucci, F., Ginestier, C., Tagett, R., Jacquemier, J., Charafe-Jauffret, E."Basal and luminal breast cancers: Basic or luminous? (Review)". International Journal of Oncology 25, no. 2 (2004): 249-258. https://doi.org/10.3892/ijo.25.2.249