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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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April 2006 Volume 28 Issue 4

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

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An International Open Access Journal Devoted to General Medicine.

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April 2006 Volume 28 Issue 4

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Article

Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma

  • Authors:
    • Kazutaka Kurokohchi
    • Tsutomu Masaki
    • Seishiro Watanabe
    • Seiji Nakai
    • Akihiro Deguchi
    • Asahiro Morishita
    • Hirohito Yoneyama
    • Tomohiro Ohgi
    • Masahiro Ono
    • Akira Yoshitake
    • Takeshi Kako
    • Naoko Ohmachi
    • Takaaki Kiuchi
    • Tsuyoshi Maeta
    • Mitsuo Yoshida
    • Yoshihiro Mori
    • Fumikazu Kohi
    • Shigeki Kuriyama

  • View Affiliations / Copyright

    Affiliations: Third Department of Internal Medicine, Kagawa University School of Medicine, Miki-cho, Kita-gun, Kagawa 761-0793, Japan
  • Pages: 971-976
    |
    Published online on: April 1, 2006
       https://doi.org/10.3892/ijo.28.4.971
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Abstract

We have previously reported that the combination therapy of percutaneous ethanol injection and radiofrequency ablation (PEI-RFA) was more effective than RFA alone to induce wider coagulated necrosis for the treatment of hepatocellular carcinoma (HCC). In the present study, the effect of time-lag performance of RFA after PEI was evaluated under the same ablation condition as PEI-RFA by analyzing the volume of coagulated necrosis, the energy requirement for ablation and the amount of ethanol injected into HCC. The comparative study between time-lag PEI-RFA and no time-lag PEI-RFA showed that the total energy requirement and the energy requirement per unit volume for whole and marginal coagulated necrosis were significantly smaller in the time-lag group than in the no time-lag PEI-RFA group. In time-lag PEI-RFA, the volume of coagulated necrosis induced positively correlated with the amount of ethanol injected into HCC as previously observed in PEI-RFA treatment. These results suggest that time-lag PEI-RFA can induce comparable coagulated necrosis with a smaller energy requirement than no time-lag PEI-RFA, and that time-lag PEI-RFA is likely to be less invasive than no time-lag PEI-RFA for inducing comparable coagulated necrosis. Thus, time-lag performance of RFA after PEI may make RFA treatment more effective and less invasive for the treatment of patients with HCC.

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Copy and paste a formatted citation
Spandidos Publications style
Kurokohchi K, Masaki T, Watanabe S, Nakai S, Deguchi A, Morishita A, Yoneyama H, Ohgi T, Ono M, Yoshitake A, Yoshitake A, et al: Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma. Int J Oncol 28: 971-976, 2006.
APA
Kurokohchi, K., Masaki, T., Watanabe, S., Nakai, S., Deguchi, A., Morishita, A. ... Kuriyama, S. (2006). Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma. International Journal of Oncology, 28, 971-976. https://doi.org/10.3892/ijo.28.4.971
MLA
Kurokohchi, K., Masaki, T., Watanabe, S., Nakai, S., Deguchi, A., Morishita, A., Yoneyama, H., Ohgi, T., Ono, M., Yoshitake, A., Kako, T., Ohmachi, N., Kiuchi, T., Maeta, T., Yoshida, M., Mori, Y., Kohi, F., Kuriyama, S."Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma". International Journal of Oncology 28.4 (2006): 971-976.
Chicago
Kurokohchi, K., Masaki, T., Watanabe, S., Nakai, S., Deguchi, A., Morishita, A., Yoneyama, H., Ohgi, T., Ono, M., Yoshitake, A., Kako, T., Ohmachi, N., Kiuchi, T., Maeta, T., Yoshida, M., Mori, Y., Kohi, F., Kuriyama, S."Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma". International Journal of Oncology 28, no. 4 (2006): 971-976. https://doi.org/10.3892/ijo.28.4.971
Copy and paste a formatted citation
x
Spandidos Publications style
Kurokohchi K, Masaki T, Watanabe S, Nakai S, Deguchi A, Morishita A, Yoneyama H, Ohgi T, Ono M, Yoshitake A, Yoshitake A, et al: Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma. Int J Oncol 28: 971-976, 2006.
APA
Kurokohchi, K., Masaki, T., Watanabe, S., Nakai, S., Deguchi, A., Morishita, A. ... Kuriyama, S. (2006). Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma. International Journal of Oncology, 28, 971-976. https://doi.org/10.3892/ijo.28.4.971
MLA
Kurokohchi, K., Masaki, T., Watanabe, S., Nakai, S., Deguchi, A., Morishita, A., Yoneyama, H., Ohgi, T., Ono, M., Yoshitake, A., Kako, T., Ohmachi, N., Kiuchi, T., Maeta, T., Yoshida, M., Mori, Y., Kohi, F., Kuriyama, S."Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma". International Journal of Oncology 28.4 (2006): 971-976.
Chicago
Kurokohchi, K., Masaki, T., Watanabe, S., Nakai, S., Deguchi, A., Morishita, A., Yoneyama, H., Ohgi, T., Ono, M., Yoshitake, A., Kako, T., Ohmachi, N., Kiuchi, T., Maeta, T., Yoshida, M., Mori, Y., Kohi, F., Kuriyama, S."Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma". International Journal of Oncology 28, no. 4 (2006): 971-976. https://doi.org/10.3892/ijo.28.4.971
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