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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2006 Volume 28 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Oncolytic recombinant herpes simplex virus for treatment of orthotopic liver tumors in nude mice

Young Sik Chung, Shin-Ichi Miyatake, Akiko Miyamoto, Yoshiharu Miyamoto, Takehiko Dohi, Nobuhiko Tanigawa
Pages: 793-798
Published online on: 01 April 2006

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Article

Expression profiles of metastatic brain tumor from lung adenocarcinomas on cDNA microarray

Takefumi Kikuchi, Yataro Daigo, Nobuhisa Ishikawa, Toyomasa Katagiri, Tatsuhiko Tsunoda, Seiichi Yoshida, Yusuke Nakamura
Pages: 799-805
Published online on: 01 April 2006

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Article

Calcitonin inhibits invasion of breast cancer cells: Involvement of urokinase-type plasminogen activator (uPA) and uPA receptor

Bo Han, Misa Nakamura, Gengyin Zhou, Aiko Ishii, Atsushi Nakamura, Yanhua Bai, Ichiro Mori, Kennichi Kakudo
Pages: 807-814
Published online on: 01 April 2006

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Article

Postnatal neovascularization by endothelial progenitor cells immortalized with the simian virus 40T antigen gene

Hui-Ying Qiu, Yoshihiro Fujimori, Keisuke Nishioka, Nobuko Yamaguchi, Tomoko Hashimoto-Tamaoki, Ayako Sugihara, Nobuyuki Terada, Noritoshi Nagaya, Munetake Kanda, Naoya Kobayashi, Noriaki Tanaka, Karen A. Westerman, Philippe Leboulch, Hiroshi Hara
Pages: 815-821
Published online on: 01 April 2006

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Article

Lysocellin, a metabolite of the novel drug ‘alopestatin’, induces G1 arrest and prevents cytotoxicity induced by etoposide

Yoshinori Takahara, Shingo Yogosawa, Sakiko Maruyama, Noriko Watanabe, Hirofumi Yokoyama, Kazuteru Fukasawa, Yoshikazu Sukenaga, Jun Kamiyama, Moriatsu Izumi, Miki Wakada, Helin Zhang, Kaname Yoshizawa, Shigeyuki Kawa, Toshio Nikaido, Toshiyuki Sakai
Pages: 823-829
Published online on: 01 April 2006

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Article

siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells

Ramesh Subramanian, Christopher S. Gondi, Sajani S. Lakka, Aman Jutla, Jasti S. Rao
Pages: 831-839
Published online on: 01 April 2006

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Article

Survivin associates with cell proliferation in renal cancer cells: Regulation of survivin expression by insulin-like growth factor-1, interferon-γ and a novel NF-κB inhibitor

Akinori Sato, Mototsugu Oya, Keiichi Ito, Ryuichi Mizuno, Yutaka Horiguchi, Kazuo Umezawa, Masamichi Hayakawa, Masaru Murai
Pages: 841-846
Published online on: 01 April 2006

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Article

Significance of Id-1 up-regulation and its association with EGFR in bladder cancer cell invasion

Yi Ding, Gang Wang, Ming Tat Ling, Y. C. Wong, Xin Li, Yanqun Na, Xiaomeng Zhang, Chee Wai Chua, Xianghong Wang, Dianqi Xin
Pages: 847-854
Published online on: 01 April 2006

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Article

Immunotherapy for patients with acute myeloid leukemia using autologous dendritic cells generated from leukemic blasts

Li Li, Krzysztof Giannopoulos, Peter Reinhardt, Jacek Tabarkiewicz, Anita Schmitt, Jochen Greiner, Jacek Rolinski, Iwona Hus, Anna Dmoszynska, Markus Wiesneth, Michael Schmitt
Pages: 855-861
Published online on: 01 April 2006

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Article

PLC-β2 is highly expressed in breast cancer and is associated with a poor outcome: a study on tissue microarrays

Valeria Bertagnolo, Mascia Benedusi, Patrizia Querzoli, Massimo Pedriali, Eros Magri, Federica Brugnoli, Silvano Capitani
Pages: 863-872
Published online on: 01 April 2006

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Article

Down-regulation of 1D-myo-inositol 1,4,5-trisphosphate 3-kinase A protein expression in oral squamous cell carcinoma

Hisashi Kato, Katsuhiro Uzawa, Takeshi Onda, Yoshikuni Kato, Kengo Saito, Dai Nakashima, Kastunori Ogawara, Hiroki Bukawa, Hidetake Yokoe, Hideki Tanzawa
Pages: 873-881
Published online on: 01 April 2006

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Article

Role of lymphangiogenesis and lymphangiogenic factors during pancreatic cancer progression and lymphatic spread

Martin Schneider, Peter Büchler, Nathalia Giese, Thomas Giese, Jörg Wilting, Markus W. Büchler, Helmut Friess
Pages: 883-890
Published online on: 01 April 2006

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Article

Novel cryptic chromosomal rearrangements detected in acute lymphoblastic leukemia detected by application of new multicolor fluorescent in situ hybridization approaches

Constanze Karst, Madeleine Gross, Detlef Haase, Ulrich Wedding, Klaus Höffken, Thomas Liehr, Hasmik Mkrtchyan
Pages: 891-897
Published online on: 01 April 2006

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Article

Fluorescence in situ hybridization and chromosomal organization of the human Sirtuin 7 gene

Susanne Voelter-Mahlknecht, Stephan Letzel, Ulrich Mahlknecht
Pages: 899-908
Published online on: 01 April 2006

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Article

Osteoblast-conditioned media stimulate membrane vesicle shedding in prostate cancer cells

Danilo Millimaggi, Claudio Festuccia, Adriano Angelucci, Sandra D'Ascenzo, Nadia Rucci, Silvio Flati, Mauro Bologna, Anna Teti, Antonio Pavan, Vincenza Dolo
Pages: 909-914
Published online on: 01 April 2006

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Article

The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines

Hideki Miyata, Tamito Sasaki, Kenichi Kuwahara, Masahiro Serikawa, Kazuaki Chayama
Pages: 915-921
Published online on: 01 April 2006

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Article

Antitumor effects of the novel NF-κB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production

Paola Poma, Monica Notarbartolo, Manuela Labbozzetta, Rosario Sanguedolce, Alessandra Alaimo, Valeria Carina, Annamaria Maurici, Antonella Cusimano, Melchiorre Cervello, Natale D'Alessandro
Pages: 923-930
Published online on: 01 April 2006

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Article

Suppression of invasive characteristics by antisense introduction of overexpressed HOX genes in ovarian cancer cells

Tsuyoshi Yamashita, Seishiro Tazawa, Zhao Yawei, Hideto Katayama, Yasuhito Kato, Kunihiko Nishiwaki, Yuko Yokohama, Mutsuo Ishikawa
Pages: 931-938
Published online on: 01 April 2006

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Article

Signal of proteinase-activated receptor-2 contributes to highly malignant potential of human pancreatic cancer by up-regulation of interleukin-8 release

Osamu Ikeda, Hiroshi Egami, Takatoshi Ishiko, Shinji Ishikawa, Hidenobu Kamohara, Hideki Hidaka, Masahumi Takahashi, Michio Ogawa
Pages: 939-946
Published online on: 01 April 2006

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Article

The boosting effect of co-transduction with cytokine genes on cancer vaccine therapy using genetically modified dendritic cells expressing tumor-associated antigen

Toshiyasu Ojima, Makoto Iwahashi, Masaki Nakamura, Kenji Matsuda, Teiji Naka, Mikihito Nakamori, Kentaro Ueda, Koichiro Ishida, Hiroki Yamaue
Pages: 947-953
Published online on: 01 April 2006

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Article

Inhibition of melanoma tumor growth by a pharmacological inhibitor of MetAP-2, PPI-2458

Gerhard Hannig, Douglas D. Lazarus, Sylvie G. Bernier, Russell M. Karp, Jeanine Lorusso, Daniel Qiu, Matthew T. Labenski, Jim D. Wakefield, Charles D. Thompson, William F. Westlin
Pages: 955-963
Published online on: 01 April 2006

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Article

Differential profiling analysis of proteins involved in anti-proliferative effect of interferon-α on renal cell carcinoma cell lines by protein biochip technology

Kogenta Nakamura, Kazuhiro Yoshikawa, Yoshiaki Yamada, Shinsuke Saga, Shigeyuki Aoki, Tomohiro Taki, Motoi Tobiume, Toru Shimazui, Hideyuki Akaza, Nobuaki Honda
Pages: 965-970
Published online on: 01 April 2006

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Article

Time-lag performance of radiofrequency ablation after percutaneous ethanol injection for the treatment of hepatocellular carcinoma

Kazutaka Kurokohchi, Tsutomu Masaki, Seishiro Watanabe, Seiji Nakai, Akihiro Deguchi, Asahiro Morishita, Hirohito Yoneyama, Tomohiro Ohgi, Masahiro Ono, Akira Yoshitake, Takeshi Kako, Naoko Ohmachi, Takaaki Kiuchi, Tsuyoshi Maeta, Mitsuo Yoshida, Yoshihiro Mori, Fumikazu Kohi, Shigeki Kuriyama
Pages: 971-976
Published online on: 01 April 2006

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Article

Effects of PPAR and RXR ligands in semaphorin 6B gene expression of human MCF-7 breast cancer cells

Hossam Murad, Philippe Collet, Cecile Huin-Schohn, Nehmann Al-Makdissy, Geraldine Kerjan, Alain Chedotal, Mireille Donner, Marie Dominique Devignes, Philippe Becuwe, Herve Schohn, Lionel Domenjoud, Michel Dauça
Pages: 977-984
Published online on: 01 April 2006

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Article

Leptin receptor expression and cell signaling in breast cancer

Krista A. Frankenberry, Heath Skinner, Ponnandai Somasundar, David W. McFadden, Linda C. Vona-Davis
Pages: 985-993
Published online on: 01 April 2006

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Article

Mutant p53 protein in serum could be used as a molecular marker in human breast cancer

G. A. Balogh, D. A. Mailo, M. M. Corte, P. Roncoroni, H. Nardi, E. Vincent, D. Martinez, M. E. Cafasso, A. Frizza, G. Ponce, E. Barutta, P. Lizarraga, G. Lizarraga, C. Monti, E. Paolillo, R. Vincent, R. Quatroquio, C. Grimi, H. Maturi, M. Aimale, C. Spinsanti, H. Montero, J. Santiago, L. Shulman, M. Rivadulla, M. Machiavelli, G. Salum, M. A. Cuevas, J. Picolini, A. Gentili, R. Gentili, J. Mordoh
Pages: 995-1002
Published online on: 01 April 2006

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Article

The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer

Jane-Jen Wang, Jen-Yi Lee, Yu-Chen Chen, Yaw-Terng Chern, Chin-Wen Chi
Pages: 1003-1012
Published online on: 01 April 2006

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Article Number: 22
Published online on: 10 December 2025

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Review Open Access

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review)

Xiao Pang, Huai Liu, Ying Long, Hui Wang
Article Number: 21
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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