MISSED NODAL METASTASES IN BREAST-CANCER

  • Authors:
    • F HARTVEIT
    • PK LILLENG
  • View Affiliations

  • Published online on: April 1, 1994     https://doi.org/10.3892/ijo.4.4.873
  • Pages: 873-876
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The routine use of immunohistochemistry has been suggested in the examination of the axillary nodes from patients with node-negative breast cancer in order to detect possible micrometastases. In this study, comprising 70 axillary specimens, we found missed micrometastases in 5 lymph nodes from a total of 40 cases following staining with epithelial membrane antigen. These metastases were also visible in the original haematoxylin and eosin stained slides, but missed on first examination. This makes a total of 10% of the cases, but only 0.8% of the nodes examined. Due to the increased expense of immunohistochemistry we would not recommend it as a routine in the examination of the axillary specimens. Until the prognostic significance of such deposits has been clearly defined we recommend hilar sectioning of the nodes, i.e. targeting of the sites of choice for micrometastases, and a second look at the slides from 'node-negative' cases, before they are reported.

Related Articles

Journal Cover

April 1994
Volume 4 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

Sign up for eToc alerts

Recommend to Library

Copy and paste a formatted citation
x
Spandidos Publications style
HARTVEIT F and HARTVEIT F: MISSED NODAL METASTASES IN BREAST-CANCER. Int J Oncol 4: 873-876, 1994
APA
HARTVEIT, F., & HARTVEIT, F. (1994). MISSED NODAL METASTASES IN BREAST-CANCER. International Journal of Oncology, 4, 873-876. https://doi.org/10.3892/ijo.4.4.873
MLA
HARTVEIT, F., LILLENG, P."MISSED NODAL METASTASES IN BREAST-CANCER". International Journal of Oncology 4.4 (1994): 873-876.
Chicago
HARTVEIT, F., LILLENG, P."MISSED NODAL METASTASES IN BREAST-CANCER". International Journal of Oncology 4, no. 4 (1994): 873-876. https://doi.org/10.3892/ijo.4.4.873