CHRONIC LYMPHOCYTIC-LEUKEMIA WITH PLEOMORPHIC LYMPHOCYTES (CLL-PLEO) - A COMPARATIVE-STUDY WITH TYPICAL CLL

  • Authors:
    • A BATATA
    • B SHEN
    • S BATATA
  • View Affiliations

  • Published online on: May 1, 1994     https://doi.org/10.3892/ijo.4.5.1083
  • Pages: 1083-1087
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Abstract

Cell suspensions from the peripheral brood of 21 cases of chronic lymphocytic leukemia with pleomorphic lymphocytes (CLL-pleo) and 155 cases of typical CLL were analyzed to define the phenotype of the former and compare it with the phenotype of the latter. CLL-pleo was characterized by weak fluorescence intensity of surface immunoglobulin (mean channel number on flow cytometry <200), positive mouse rosettes and CD5, and negative CD22 and tartrate resistant acid phosphatase. Comparison of the positive rates of the markers and of the mean percentages of marker-expressing cells showed no statistical difference between CLL-pleo and typical CLL. CLL-pleo constitutes a morphological variant of typical CLL bearing the same membrane phenotype as typical CLL, although the mean absolute lymphocyte count in CLL-pleo was significantly higher than that of typical CLL.

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May 1994
Volume 4 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
BATATA A, SHEN B and BATATA S: CHRONIC LYMPHOCYTIC-LEUKEMIA WITH PLEOMORPHIC LYMPHOCYTES (CLL-PLEO) - A COMPARATIVE-STUDY WITH TYPICAL CLL. Int J Oncol 4: 1083-1087, 1994.
APA
BATATA, A., SHEN, B., & BATATA, S. (1994). CHRONIC LYMPHOCYTIC-LEUKEMIA WITH PLEOMORPHIC LYMPHOCYTES (CLL-PLEO) - A COMPARATIVE-STUDY WITH TYPICAL CLL. International Journal of Oncology, 4, 1083-1087. https://doi.org/10.3892/ijo.4.5.1083
MLA
BATATA, A., SHEN, B., BATATA, S."CHRONIC LYMPHOCYTIC-LEUKEMIA WITH PLEOMORPHIC LYMPHOCYTES (CLL-PLEO) - A COMPARATIVE-STUDY WITH TYPICAL CLL". International Journal of Oncology 4.5 (1994): 1083-1087.
Chicago
BATATA, A., SHEN, B., BATATA, S."CHRONIC LYMPHOCYTIC-LEUKEMIA WITH PLEOMORPHIC LYMPHOCYTES (CLL-PLEO) - A COMPARATIVE-STUDY WITH TYPICAL CLL". International Journal of Oncology 4, no. 5 (1994): 1083-1087. https://doi.org/10.3892/ijo.4.5.1083