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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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September 1994 Volume 5 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
September 1994 Volume 5 Issue 3

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Article

ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS

  • Authors:
    • O ROSEN
    • C SCHYMANIETZ
    • F HOLZEL
  • View Affiliations / Copyright

    Affiliations: UNIV HAMBURG,HOSP EPPENDORF,INST PHYSIOL CHEM,D-20246 HAMBURG,GERMANY. UNIV HAMBURG,HOSP EPPENDORF,DEPT GYNECOL,D-20246 HAMBURG,GERMANY.
  • Pages: 517-523
    |
    Published online on: September 1, 1994
       https://doi.org/10.3892/ijo.5.3.517
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Abstract

Antiproliferative and cytotoxic efficacies of the phospholipids OPP and HPC were compared in a panel of 10 human and rat tumor cell lines. The dose ranges were similar for the inhibition of cell growth measured by ID50 and for the cytotoxic effect (LD(50)). The ratios of LD(50)/ID50 revealed variations between the individual cell lines. After initial inhibition by twice the ID50 complete recovery of proliferation was observed in OPP withdrawal experiments. Cultivation in the continuous presence of OPP resulted in the recovery of proliferation in 3 of 5 cell lines tested, apparently based on resistant subpopulations.

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Copy and paste a formatted citation
Spandidos Publications style
ROSEN O, SCHYMANIETZ C and HOLZEL F: ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS. Int J Oncol 5: 517-523, 1994.
APA
ROSEN, O., SCHYMANIETZ, C., & HOLZEL, F. (1994). ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS. International Journal of Oncology, 5, 517-523. https://doi.org/10.3892/ijo.5.3.517
MLA
ROSEN, O., SCHYMANIETZ, C., HOLZEL, F."ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS". International Journal of Oncology 5.3 (1994): 517-523.
Chicago
ROSEN, O., SCHYMANIETZ, C., HOLZEL, F."ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS". International Journal of Oncology 5, no. 3 (1994): 517-523. https://doi.org/10.3892/ijo.5.3.517
Copy and paste a formatted citation
x
Spandidos Publications style
ROSEN O, SCHYMANIETZ C and HOLZEL F: ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS. Int J Oncol 5: 517-523, 1994.
APA
ROSEN, O., SCHYMANIETZ, C., & HOLZEL, F. (1994). ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS. International Journal of Oncology, 5, 517-523. https://doi.org/10.3892/ijo.5.3.517
MLA
ROSEN, O., SCHYMANIETZ, C., HOLZEL, F."ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS". International Journal of Oncology 5.3 (1994): 517-523.
Chicago
ROSEN, O., SCHYMANIETZ, C., HOLZEL, F."ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS". International Journal of Oncology 5, no. 3 (1994): 517-523. https://doi.org/10.3892/ijo.5.3.517
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