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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

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International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

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Journal Cover
September 1994 Volume 5 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

ADENOVIRUS E1A PROTEINS AND TRANSFORMATION (REVIEW)

ST BAYLEY, JS MYMRYK
Pages: 425-444
Published online on: 01 September 1994

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Article

EXPRESSION OF CRIPTO-1 IN HUMAN COLORECTAL ADENOMAS AND CARCINOMAS IS RELATED TO THE DEGREE OF DYSPLASIA

T SAEKI, DS SALOMON, WJ GULLICK, K MANDAI, K YAMAGAMI, S MORIWAKI, S TAKASHIMA, Y NISHIKAWA, E TAHARA
Pages: 445-451
Published online on: 01 September 1994

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Article

PCR AMPLIFICATION OF 40-YEAR-OLD PARAFFIN-EMBEDDED TUMOR-TISSUES - COMPARISON OF 4 DIFFERENT DNA EXTRACTION AND PURIFICATION METHODS

WG WANG, P KUMAR, M SCHWARZ, G MALONE, A HAWORTH, S KUMAR
Pages: 453-457
Published online on: 01 September 1994

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Article

CHARACTERIZATION OF VARIANTS OF A HUMAN BREAST-CANCER CELL-LINE ISOLATED FROM METASTASES IN DIFFERENT ORGANS OF NUDE-MICE

JE PRICE, A FABRA, RD ZHANG, R RADINSKY, S PATHAK
Pages: 459-467
Published online on: 01 September 1994

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Article

EXPRESSION OF CYCLIN D1 IN SQUAMOUS-CELL CARCINOMAS OF THE HEAD AND NECK

JM LUCAS, RE MOUNTAIN, AW GRAMZA, DE SCHULLER, NM WILKIE, JC LANG
Pages: 469-472
Published online on: 01 September 1994

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Article

HER-2/NEU AND FIBRINOLYTIC FACTORS IN HUMAN BREAST-CANCER

S TOMMASI, C RELLA, C GIANNELLA, M QUARANTA, F SCHITTULLI, A PARADISO, M COVIELLO, M DELENA
Pages: 473-477
Published online on: 01 September 1994

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Article

A METHOD TO DETECT AND QUANTITATE THE EXPRESSION OF NORMAL VERSUS MUTANT H-RAS TRANSCRIPTS AT CODON-12

A KOTSINAS, H KIARIS, DA SPANDIDOS
Pages: 479-483
Published online on: 01 September 1994

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Article

BROMELAIN PROTEINASES MODULATE THE CD44 EXPRESSION ON HUMAN MOLT-4/8 LEUKEMIA AND SK-MEL-28 MELANOMA-CELLS IN-VITRO

T HARRACH, F GEBAUER, K ECKERT, R KUNZE, HR MAURER
Pages: 485-488
Published online on: 01 September 1994

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Article

THE RET PROTOONCOGENE IS EXPRESSED IN PREDOMINANTLY EPITHELIAL HUMAN THYMOMAS

N FABIEN, C PAULIN, M SANTORO, G CHIAPPETTA, G BOTTI, M GRIECO, PM DUBOIS, A FUSCO
Pages: 489-493
Published online on: 01 September 1994

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Article

P53 EXPRESSION IN STAGE III-IV SQUAMOUS-CELL CARCINOMA OF THE LARYNX - AN IMMUNOHISTOCHEMICAL STUDY RELATED TO CLINICOPATHOLOGICAL, FLOW-CYTOMETRIC DNA ANALYSIS AND PROGNOSIS

RM TOMASINO, V MORELLO, V BAZAN, C NAGAR, V TRALONGO, G DARDANONI, F INGRIA, G MONTELEONE, S RESTIVO, R NUARA, E DANIELE, A RUSSO
Pages: 495-500
Published online on: 01 September 1994

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Article

SCID MICE MODEL FOR THE IN-VIVO STUDY OF HUMAN ONCOTHERAPY - STUDIES ON THE GROWTH AND METASTASIS OF HUMAN LUNG-CANCER

S TERAOKA, S KYOIZUMI, T SEYAMA, M YAMAKIDO, M AKIYAMA
Pages: 501-508
Published online on: 01 September 1994

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Article

CATHEPSIN-D ACTIVITY LEVELS IN COLORECTAL-CANCER - CORRELATION WITH CATHEPSIN-B AND CATHEPSIN-L AND OTHER BIOLOGICAL AND CLINICAL-PARAMETERS

G LETO, FM TUMMINELLO, A RUSSO, G PIZZOLANTI, V BAZAN, N GEBBIA
Pages: 509-515
Published online on: 01 September 1994

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Article

ANTIPROLIFERATIVE, CYTOTOXIC AND RECOVERY EFFECTS IN TUMOR-CELL CULTURES TREATED WITH SYNTHETIC PHOSPHOLIPIDS

O ROSEN, C SCHYMANIETZ, F HOLZEL
Pages: 517-523
Published online on: 01 September 1994

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Article

TGF-BETA-INDUCED APOPTOSIS OF TRANSFORMED FIBROBLASTS BY NORMAL FIBROBLASTS - INDEPENDENCE OF CELL-TO-CELL CONTACT AND DEPENDENCE ON REACTIVE OXYGEN SPECIES

JM JURGENSMEIER, P HOFLER, G BAUER
Pages: 525-531
Published online on: 01 September 1994

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Article

ASSOCIATION OF P53 EXPRESSION WITH PROLIFERATIVE ACTIVITY AND POOR-PROGNOSIS IN PATIENTS WITH SQUAMOUS-CELL LUNG CARCINOMAS

M VOLM, J MATTERN, S HECKER, EW POMMERENKE
Pages: 533-538
Published online on: 01 September 1994

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Article

TUMOR-SUPPRESSOR GENES IN COLORECTAL CARCINOMAS - P53 INACTIVATION IS HIGHLY ASSOCIATED WITH ALLELIC LOSS OF CHROMOSOME 5Q

DR SMITH, K KHINE, CS CHAN, HS GOH
Pages: 539-546
Published online on: 01 September 1994

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Article

TRANSFORMING GROWTH-FACTOR-ALPHA MODULATES REPLICATION AND DIFFERENTIATION MARKERS ON A HUMAN NEUROBLASTOMA CELL-LINE

S SCARPA, G MINCIONE, M RAGANO-CARACCIOLO, A MODESTI, G COLLETTA
Pages: 547-552
Published online on: 01 September 1994

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Article

LEVELS OF P53 ANTIGEN IN THE SERUM OF NONSMALL CELL LUNG-CANCER PATIENTS CORRELATE WITH POSITIVE P53 IMMUNOHISTOCHEMISTRY ON TUMOR SECTIONS, TUMOR NECROSIS AND NODAL INVOLVEMENT

G FONTANINI, L FIORE, D BIGINI, S VIGNATI, S CALVO, A MUSSI, M LUCCHI, CA ANGELETTI, GR MERLO, F BASOLO
Pages: 553-558
Published online on: 01 September 1994

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Article

PROGNOSTIC INDICATORS FOR EARLY-STAGE BREAST-CARCINOMA .2. VALUE OF CATHEPSIN-D EXPRESSION, DETECTED BY IMMUNOCYTOCHEMISTRY - A MULTIPARAMETRIC STUDY

P BEVILACQUA, P BORACCHI, G GASPARINI
Pages: 559-564
Published online on: 01 September 1994

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Article

VARIABLE P-GLYCOPROTEIN IMMUNOREACTIVITY UNRELATED TO CYTOTOXIC DRUG-RESISTANCE IN-VITRO OF HUMAN ADRENOCORTICAL CARCINOMA

C BACKLIN, H FRIDBORG, C JUHLIN, P NYGREN, G AKERSTROM, J RASTAD, R LARSSON
Pages: 565-571
Published online on: 01 September 1994

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Article

INTEGRIN BETA-4 EXPRESSION IN COLORECTAL-CANCER

R FALCIONI, V TURCHI, P VITULLO, G NAVARRA, F FICARI, F CAVALIERE, A SACCHI, R MARIANICOSTANTINI
Pages: 573-578
Published online on: 01 September 1994

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Article

LOSS OF HETEROZYGOSITY AND MICROSATELLITE INSTABILITY OF THE H-RAS GENE IN CANCER OF THE HEAD AND NECK

H KIARIS, DA SPANDIDOS, AS JONES, JK FIELD
Pages: 579-582
Published online on: 01 September 1994

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Article

DIFFERENT PATTERNS OF P53 GENE-MUTATIONS IN ENDOMETRIAL CARCINOMAS AND ENDOMETRIOID CARCINOMAS OF THE OVARY

M SAWAIRI-ITOH, A IMAI, T MURASE, K NIWA, N ITOH, H MORI, T TAMAYA
Pages: 583-588
Published online on: 01 September 1994

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Article

DNA HISTOGRAM TYPING AND DNA INDEX MEASUREMENTS IN 508 INVASIVE BREAST CARCINOMAS FROM FINE-NEEDLE ASPIRATES AND IMPRINT SMEARS AS OPPOSED TO FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUES

P GASPERIN, V BUDEL, M PETEIN, JL PASTEELS, R KISS
Pages: 589-595
Published online on: 01 September 1994

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Article

DNA CROSS-LINKING AND REPAIR IN CISPLATIN-RESISTANT HUMAN TUMOR-CELLS FOLLOWING EXPOSURE TO A NEW CISPLATIN ANALOG, CI-973

LY YANG, YZ LIU, L LI, HH KANTARJIAN, MJ KEATING
Pages: 597-602
Published online on: 01 September 1994

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Article

AUTONOMOUSLY REPLICATING SEQUENCES IDENTIFIED IN TRANSCRIPTIONAL REGULATORY REGIONS OF HUMAN N-MYC GENE

T NAKAGAWA, Y IMAMURA, SMM IGUCHIARIGA, H ARIGA
Pages: 603-609
Published online on: 01 September 1994

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Article

ONCOGENES AND CELLULAR-SENSITIVITY TO RADIOTHERAPY - A STUDY ON MURINE KERATINOCYTES TRANSFORMED BY V-H-RAS, V-MYC, V-NEU, ADENOVIRUS E1A AND MUTANT P53

E MARCHETTI, J ROMERO, R SANCHEZ, JA VARGAS, C DOMINGUEZ, JC LACAL, SRY CAJAL
Pages: 611-618
Published online on: 01 September 1994

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Article

SERUM MODIFIES THE CONCENTRATION-DEPENDENT EFFECTS THAT SEX STEROIDS EXERT ON CGMP AND CAMP LEVELS, AND THE GROWTH OF HUMAN C4-I CELLS (CARCINOMA OF THE UTERINE CERVIX)

A ORBO, R JAEGER, G SAGER
Pages: 619-625
Published online on: 01 September 1994

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Article

PERIPHERAL BENZODIAZEPINE RECEPTORS IN ANDROGEN SENSITIVE DUNNING RAT PROSTATIC ADENOCARCINOMA

J ALENFALL, S BATRA
Pages: 627-631
Published online on: 01 September 1994

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Article

FLOW CYTOMETRIC DNA ANALYSIS IN PREDICTION OF INTRAVESICAL RECURRENCE FROM HUMAN BLADDER-CANCER

A RUSSO, V BAZAN, R CAMPANELLA, G DARDANONI, I CARRECA, S CUCCIARRE, A VECCHIONE, M PAVONEMACALUSO
Pages: 633-638
Published online on: 01 September 1994

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Article

A COMPARISON OF 4 METHODS FOR ASSESSING TUMOR VASCULARITY IN CARCINOMA OF THE CERVIX

SE DAVIDSON, R NGAN, DP WILKS, JV MOORE, CML WEST
Pages: 639-645
Published online on: 01 September 1994

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Article

ORG-2766, AN ACTH(4-9)-MSH(4-9) ANALOG, MODULATES VINCRISTINE-INDUCED NEUROTOXICITY IN THE SNAIL LYMNAEA-STAGNALIS

LJ MULLER, CM MOORERVANDELFT, B KIBURG, JB VERMORKEN, JJ HEIMANS, HH BOER
Pages: 647-653
Published online on: 01 September 1994

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Article

REVERSIBLE PROLIFERATION ARREST OF RAT 3Y1 FIBROBLASTS AND SELECTIVE KILLING OF SIMIAN-VIRUS TRANSFORMED DERIVATION OF 3Y1 BY SHORT-CHAIN FATTY-ACIDS

N MATSUO, K YAMADA, S NODA, K YAMASHITA, A OKUDA, G KIMURA, M SUGANO
Pages: 655-660
Published online on: 01 September 1994

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Article

RECOMBINANT RET ONCOGENE PRODUCTS INDUCE T-LYMPHOCYTE PROLIFERATION, AND SUPPRESS LYMPHOMA DERIVED FROM RET TRANSGENIC MICE

D YAN, K ISOBE, M TAKAHASHI, I NAKASHIMA
Pages: 661-665
Published online on: 01 September 1994

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Article

A NEW 42-KDA PROTEIN-BINDING TO THE GROWTH SUPPRESSOR PROTEIN-P53

K APPEL, E SCHNEIDER, P WAGNER, JO HOOG, M MONTENARH, C KARLSSON
Pages: 667-673
Published online on: 01 September 1994

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Article

THE EFFECT OF LOW-DOSE OKT3 MONOCLONAL-ANTIBODY THERAPY ON K562 CYTOTOXICITY IN HUMAN CANCER-PATIENTS

J HOLLINGWORTH, RE CATTERICK, T HORSBURGH, PS VEITCH, PRF BELL
Pages: 675-681
Published online on: 01 September 1994

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Article

ANTI-CD3 AND ANTI-CD16 MONOCLONAL-ANTIBODY IN-VITRO ENHANCEMENT OF NK ACTIVITY IN PBL FROM GASTROINTESTINAL-TRACT CANCER-PATIENTS

RE CATTERICK, J HOLLINGWORTH, T HORSBURGH, PS VEITCH, PRF BELL, RFL JAMES
Pages: 683-688
Published online on: 01 September 1994

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Article

INTEGRINS AND THEIR EXTRACELLULAR-MATRIX LIGANDS IN GASTRIC-CANCER

YD RAMKISSOON, R DEL BUONO, IM FILIPE, S BUK, PA HALL, M PIGNATELLI
Pages: 689-695
Published online on: 01 September 1994

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Article

BACILLUS-CALMETTE-GUERIN (BCG) ORGANISMS DIRECTLY ALTER THE GROWTH OF BLADDER-TUMOR CELLS

AM JACKSON, AB ALEXANDROFF, D FLEMING, S PRESCOTT, GD CHISHOLM, K JAMES
Pages: 697-703
Published online on: 01 September 1994

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Momo
Article Number: 58
Published online on: 13 March 2026

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Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.k.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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