search button

COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES

  • Authors:
    • A DIB
    • J ADELAIDE
    • F COURJAL
    • A COURSEAUX
    • J JACQUEMIER
    • P GAUDRAY
    • C THEILLET
    • MJ PEBUSQUE
    • D BIRNBAUM

  • View Affiliations

  • Published online on: December 1, 1994     https://doi.org/10.3892/ijo.5.6.1375
  • Pages: 1375-1378
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )


Abstract

The CCND2 and FGF6 genes are both located at band p13 of human chromosome 12. The two genes are coamplified in some cases (3.6%) of breast tumors. They are physically linked within a 500 kb genomic segment. Thus, both 11q13 and 12p13 chromosomal regions host related linked cyclin and FGF genes, and can be amplified in human tumors. This strengthens the hypothesis of genome duplication involving chromosomes 11 and 12.

Related Articles

Journal Cover

December 1994
Volume 5 Issue 6

Print ISSN: 1019-6439
Online ISSN:1791-2423

Sign up for eToc alerts

Recommend to Library

  • Journal Metrics
  • Impact Factor: 5.2
  • Ranked Oncology
    (total number of cites)
  • CiteScore: 11.4
  • CiteScore Rank: Q1: #40/366 Oncology
  • Source Normalized Impact per Paper (SNIP): 1.125
  • SCImago Journal Rank (SJR): 1.105
International Symposium on Molecular Medicine Conference Banner
The Cancer Story
World Congress on Advances in Oncology and International Symposium on Molecular Medicine Conference Banner
World Academy Of Sciences Banner
Heyday Road Banner

0

Copy and paste a formatted citation
x
Spandidos Publications style
DIB A, ADELAIDE J, COURJAL F, COURSEAUX A, JACQUEMIER J, GAUDRAY P, THEILLET C, PEBUSQUE M and BIRNBAUM D: COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES. Int J Oncol 5: 1375-1378, 1994
APA
DIB, A., ADELAIDE, J., COURJAL, F., COURSEAUX, A., JACQUEMIER, J., GAUDRAY, P. ... BIRNBAUM, D. (1994). COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES. International Journal of Oncology, 5, 1375-1378. https://doi.org/10.3892/ijo.5.6.1375
MLA
DIB, A., ADELAIDE, J., COURJAL, F., COURSEAUX, A., JACQUEMIER, J., GAUDRAY, P., THEILLET, C., PEBUSQUE, M., BIRNBAUM, D."COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES". International Journal of Oncology 5.6 (1994): 1375-1378.
Chicago
DIB, A., ADELAIDE, J., COURJAL, F., COURSEAUX, A., JACQUEMIER, J., GAUDRAY, P., THEILLET, C., PEBUSQUE, M., BIRNBAUM, D."COAMPLIFICATION IN HUMAN BREAST-TUMORS AND PHYSICAL LINKAGE AT CHROMOSOMAL BAND 12P13, OF CCND2 AND FGF6 GENES". International Journal of Oncology 5, no. 6 (1994): 1375-1378. https://doi.org/10.3892/ijo.5.6.1375