CORRELATION BETWEEN TPS AND CEA IN PATIENTS WITH COLORECTAL-CANCER

  • Authors:
    • B KLEIN
    • I LEVIN
    • M MICHAELI
    • LR WOLFSON
    • R GAL
    • I SHAPIRA
    • B KFIR
    • E RAKOVSKY
    • T KLEIN
  • View Affiliations

  • Published online on: August 1, 1995     https://doi.org/10.3892/ijo.7.2.267
  • Pages: 267-271
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Abstract

Serum TPS and CEA levels were measured in 173 cancer patients with various disease stages. The patients were divided into 4 groups: preoperative group, 16 patients in whom TPS and CEA were measured pre- and postoperatively; group I, 66 newly diagnosed patients up to 40 days post surgery; group II, 86 patients whose blood was taken 40-365 days post surgery, and group III, 47 patients on long-term follow-up in whom blood was taken more than one year after surgery. The median preoperative TPS levels were significantly higher (p<0.01) than the postoperative levels. Patients with Dukes' D had significantly higher TPS (p<0.01) and CEA levels as compared to patients with Dukes' B or C. For both Dukes' B and C stages there was a significant increase in median TPS level between group I and II and III. There was no similar increase in median CEA level. Serial measurements in individual patients show a significant increase in TPS levels between groups I, II and III. In Dukes' D patients, individual TPS levels decreased in response to therapy. There was a significant correlation between TPS and CEA levels. These results suggest that TPS measurement is additive to CEA in follow-up of asymptomatic patients, and to monitor response to therapy in patients with metastatic disease.

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August 1995
Volume 7 Issue 2

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
KLEIN B, LEVIN I, MICHAELI M, WOLFSON L, GAL R, SHAPIRA I, KFIR B, RAKOVSKY E and KLEIN T: CORRELATION BETWEEN TPS AND CEA IN PATIENTS WITH COLORECTAL-CANCER. Int J Oncol 7: 267-271, 1995.
APA
KLEIN, B., LEVIN, I., MICHAELI, M., WOLFSON, L., GAL, R., SHAPIRA, I. ... KLEIN, T. (1995). CORRELATION BETWEEN TPS AND CEA IN PATIENTS WITH COLORECTAL-CANCER. International Journal of Oncology, 7, 267-271. https://doi.org/10.3892/ijo.7.2.267
MLA
KLEIN, B., LEVIN, I., MICHAELI, M., WOLFSON, L., GAL, R., SHAPIRA, I., KFIR, B., RAKOVSKY, E., KLEIN, T."CORRELATION BETWEEN TPS AND CEA IN PATIENTS WITH COLORECTAL-CANCER". International Journal of Oncology 7.2 (1995): 267-271.
Chicago
KLEIN, B., LEVIN, I., MICHAELI, M., WOLFSON, L., GAL, R., SHAPIRA, I., KFIR, B., RAKOVSKY, E., KLEIN, T."CORRELATION BETWEEN TPS AND CEA IN PATIENTS WITH COLORECTAL-CANCER". International Journal of Oncology 7, no. 2 (1995): 267-271. https://doi.org/10.3892/ijo.7.2.267