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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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September 1995 Volume 7 Issue 3

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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September 1995 Volume 7 Issue 3

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Article

POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION

  • Authors:
    • A DE
    • N BOYADJIEVA
    • MG PASTORCIC
    • DK SARKAR

  • View Affiliations / Copyright

    Affiliations: WASHINGTON STATE UNIV, DEPT VET & COMPARAT ANAT PHARMACOL & PHYSIOL, PULLMAN, WA 99164 USA.
  • Pages: 643-648
    |
    Published online on: September 1, 1995
       https://doi.org/10.3892/ijo.7.3.643
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Abstract

The effect of alcohol on estrogen-regulated lactotropic cell proliferation was examined in Fisher 344 rats. Alcohol was administered for 2 weeks using liquid diet containing 8.7% ethanol (v/v) and 37% ethanol-derived calories. The control group was pair-fed with an isocaloric diet minus the ethanol or adlib-fed with normal diet. Ethanol-treated rats showed mean blood ethanol concentrations between 60-90 mg/dl. Alcohol treatment did not effect the body growth rate, but increased the DNA synthesis in lactotropes and reduced the levels of lactotropic growth inhibitory transforming growth factor-beta 1 (TGF-beta 1) protein and mRNA in the pituitary. These results suggest that alcohol promotes estrogen-induced lactotropic proliferation, possibly by down regulating the inhibitory TGF-beta 1 control of lactotropic function.

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Copy and paste a formatted citation
Spandidos Publications style
DE A, BOYADJIEVA N, PASTORCIC M and SARKAR D: POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION. Int J Oncol 7: 643-648, 1995.
APA
DE, A., BOYADJIEVA, N., PASTORCIC, M., & SARKAR, D. (1995). POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION. International Journal of Oncology, 7, 643-648. https://doi.org/10.3892/ijo.7.3.643
MLA
DE, A., BOYADJIEVA, N., PASTORCIC, M., SARKAR, D."POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION". International Journal of Oncology 7.3 (1995): 643-648.
Chicago
DE, A., BOYADJIEVA, N., PASTORCIC, M., SARKAR, D."POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION". International Journal of Oncology 7, no. 3 (1995): 643-648. https://doi.org/10.3892/ijo.7.3.643
Copy and paste a formatted citation
x
Spandidos Publications style
DE A, BOYADJIEVA N, PASTORCIC M and SARKAR D: POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION. Int J Oncol 7: 643-648, 1995.
APA
DE, A., BOYADJIEVA, N., PASTORCIC, M., & SARKAR, D. (1995). POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION. International Journal of Oncology, 7, 643-648. https://doi.org/10.3892/ijo.7.3.643
MLA
DE, A., BOYADJIEVA, N., PASTORCIC, M., SARKAR, D."POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION". International Journal of Oncology 7.3 (1995): 643-648.
Chicago
DE, A., BOYADJIEVA, N., PASTORCIC, M., SARKAR, D."POTENTIATION OF THE MITOGENIC EFFECT OF ESTROGEN ON THE PITUITARY-GLAND BY ALCOHOL-CONSUMPTION". International Journal of Oncology 7, no. 3 (1995): 643-648. https://doi.org/10.3892/ijo.7.3.643
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