Survival benefit for patients with colorectal cancer detected by population-based screening program using an immunochemical fecal occult blood test

  • Authors:
    • T Wada
    • H Saito
    • Y Soma
    • J Koeda
    • H Kawaguchi
    • M Tanaka
    • Y Yoshida
    • A Munakata
  • View Affiliations

  • Published online on: October 1, 1996     https://doi.org/10.3892/ijo.9.4.685
  • Pages: 685-691
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Abstract

The effectiveness of screening for colorectal cancer by an immunochemical fecal occult blood test was investigated by comparing the survival time of 194 screen-detected colorectal cancer subjects (screen-detected group) with that of 352 routinely diagnosed subjects (control group). The rate of Dukes' A cancers was significantly higher in screen-detected group than in the control group (43.8% vs 16.8%, p<0.0001), whereas that of Dukes' D cancer was the opposite (5.7% vs 21.3%, p<0.0001). The survival rate for screen-detected group was higher than that for the control group (Kaplan-Meier method, p<0.0001). By a proportional hazard model with adjustment for prognostic factors except stage, the risk ratio of death from colorectal cancer was 0.40 (p=0.0007) for screen-detected group versus the control group. Therefore, the screening was suggested to be effective in survival benefit, although there might be potential biases inherent in observational studies.

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October 1996
Volume 9 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Wada T, Saito H, Soma Y, Koeda J, Kawaguchi H, Tanaka M, Yoshida Y and Munakata A: Survival benefit for patients with colorectal cancer detected by population-based screening program using an immunochemical fecal occult blood test. Int J Oncol 9: 685-691, 1996
APA
Wada, T., Saito, H., Soma, Y., Koeda, J., Kawaguchi, H., Tanaka, M. ... Munakata, A. (1996). Survival benefit for patients with colorectal cancer detected by population-based screening program using an immunochemical fecal occult blood test. International Journal of Oncology, 9, 685-691. https://doi.org/10.3892/ijo.9.4.685
MLA
Wada, T., Saito, H., Soma, Y., Koeda, J., Kawaguchi, H., Tanaka, M., Yoshida, Y., Munakata, A."Survival benefit for patients with colorectal cancer detected by population-based screening program using an immunochemical fecal occult blood test". International Journal of Oncology 9.4 (1996): 685-691.
Chicago
Wada, T., Saito, H., Soma, Y., Koeda, J., Kawaguchi, H., Tanaka, M., Yoshida, Y., Munakata, A."Survival benefit for patients with colorectal cancer detected by population-based screening program using an immunochemical fecal occult blood test". International Journal of Oncology 9, no. 4 (1996): 685-691. https://doi.org/10.3892/ijo.9.4.685