Clinical significance of E-cadherin and vimentin co-expression in breast cancer

  • Authors:
    • R Yagasaki
    • M Noguchi
    • M Minami
    • M Earashi
  • View Affiliations

  • Published online on: October 1, 1996     https://doi.org/10.3892/ijo.9.4.755
  • Pages: 755-761
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Abstract

We examined the clinical significance of E-cadherin and vimentin expression in 83 patients with breast dancer. E-cadherin expression was correlated with axillary metastases, histologic grade, recurrence and disease-free survival, but not with overall survival. On the other hand, vimentin expression was correlated with axillary metastases and histologic grade, but not with recurrence, disease-free or overall survival. However, the co-expression of E-cadherin and vimentin was associated with axillary metastases, histologic grade and recurrence, and appeared as the most important prognostic factor in disease-free and overall survival. We therefore concluded that E-cadherin and vimentin expression in combination might provide prognostic information for breast cancer patients.

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October 1996
Volume 9 Issue 4

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Yagasaki R, Noguchi M, Minami M and Earashi M: Clinical significance of E-cadherin and vimentin co-expression in breast cancer. Int J Oncol 9: 755-761, 1996.
APA
Yagasaki, R., Noguchi, M., Minami, M., & Earashi, M. (1996). Clinical significance of E-cadherin and vimentin co-expression in breast cancer. International Journal of Oncology, 9, 755-761. https://doi.org/10.3892/ijo.9.4.755
MLA
Yagasaki, R., Noguchi, M., Minami, M., Earashi, M."Clinical significance of E-cadherin and vimentin co-expression in breast cancer". International Journal of Oncology 9.4 (1996): 755-761.
Chicago
Yagasaki, R., Noguchi, M., Minami, M., Earashi, M."Clinical significance of E-cadherin and vimentin co-expression in breast cancer". International Journal of Oncology 9, no. 4 (1996): 755-761. https://doi.org/10.3892/ijo.9.4.755