Regional differences of physiological functions and cancer susceptibility in the human large intestine

  • Authors:
    • A Cats
    • E DeVries
    • N Mulder
    • J Kleibeuker
  • View Affiliations

  • Published online on: November 1, 1996     https://doi.org/10.3892/ijo.9.5.1055
  • Pages: 1055-1069
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Abstract

Regional differences in function, metabolism and morphology between proximal colon, distal colon and rectum may be important in the pathogenesis and biologic behaviour of tumours originating from these segments. Thus, the effect of primary prevention of colorectal cancer may also differ from one large bowel segment to another. Therefore, this review underscores that one should be careful extrapolating results obtained in a short segment of the large bowel to the entire colorectum. Obviously, future studies concerning the pathogenesis and possibilities for prevention of large bowel cancer should certainly examine results by subsite as a routine procedure.

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November 1996
Volume 9 Issue 5

Print ISSN: 1019-6439
Online ISSN:1791-2423

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Spandidos Publications style
Cats A, DeVries E, Mulder N and Kleibeuker J: Regional differences of physiological functions and cancer susceptibility in the human large intestine. Int J Oncol 9: 1055-1069, 1996
APA
Cats, A., DeVries, E., Mulder, N., & Kleibeuker, J. (1996). Regional differences of physiological functions and cancer susceptibility in the human large intestine. International Journal of Oncology, 9, 1055-1069. https://doi.org/10.3892/ijo.9.5.1055
MLA
Cats, A., DeVries, E., Mulder, N., Kleibeuker, J."Regional differences of physiological functions and cancer susceptibility in the human large intestine". International Journal of Oncology 9.5 (1996): 1055-1069.
Chicago
Cats, A., DeVries, E., Mulder, N., Kleibeuker, J."Regional differences of physiological functions and cancer susceptibility in the human large intestine". International Journal of Oncology 9, no. 5 (1996): 1055-1069. https://doi.org/10.3892/ijo.9.5.1055