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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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January 2011 Volume 38 Issue 1

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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January 2011 Volume 38 Issue 1

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Article Open Access

miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples

  • Authors:
    • M. Rentoft
    • J. Fahlén
    • P. J. Coates
    • G. Laurell
    • B. Sjöström
    • P. Rydén
    • K. Nylander

  • View Affiliations / Copyright

    Affiliations: Department of Medical Biosciences/Pathology, Umeå University, SE 901 85, Sweden
  • Pages: 61-69
    |
    Published online on: January 1, 2011
       https://doi.org/10.3892/ijo_00000824
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Abstract

Global miRNA expression arrays were used for analysis of 836 miRNAs in formalin-fixed paraffin-embedded samples from 21 tongue cancer patients and 8 controls. Samples had been stored for one to eleven years. Results separated tumour samples from controls, however, the largest variation was correlated to sample storage time, detectable already after one year. With the use of a linear regression model we could adjust for the storage-dependent effect, leading to the identification of 54 differentially expressed miRNAs in tongue cancer, compared to 16 when using standard normalization, including up-regulation of a novel miRNA, miR-424.

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Copy and paste a formatted citation
Spandidos Publications style
Rentoft M, Fahlén J, Coates PJ, Laurell G, Sjöström B, Rydén P and Nylander K: miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. Int J Oncol 38: 61-69, 2011.
APA
Rentoft, M., Fahlén, J., Coates, P.J., Laurell, G., Sjöström, B., Rydén, P., & Nylander, K. (2011). miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. International Journal of Oncology, 38, 61-69. https://doi.org/10.3892/ijo_00000824
MLA
Rentoft, M., Fahlén, J., Coates, P. J., Laurell, G., Sjöström, B., Rydén, P., Nylander, K."miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples". International Journal of Oncology 38.1 (2011): 61-69.
Chicago
Rentoft, M., Fahlén, J., Coates, P. J., Laurell, G., Sjöström, B., Rydén, P., Nylander, K."miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples". International Journal of Oncology 38, no. 1 (2011): 61-69. https://doi.org/10.3892/ijo_00000824
Copy and paste a formatted citation
x
Spandidos Publications style
Rentoft M, Fahlén J, Coates PJ, Laurell G, Sjöström B, Rydén P and Nylander K: miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. Int J Oncol 38: 61-69, 2011.
APA
Rentoft, M., Fahlén, J., Coates, P.J., Laurell, G., Sjöström, B., Rydén, P., & Nylander, K. (2011). miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. International Journal of Oncology, 38, 61-69. https://doi.org/10.3892/ijo_00000824
MLA
Rentoft, M., Fahlén, J., Coates, P. J., Laurell, G., Sjöström, B., Rydén, P., Nylander, K."miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples". International Journal of Oncology 38.1 (2011): 61-69.
Chicago
Rentoft, M., Fahlén, J., Coates, P. J., Laurell, G., Sjöström, B., Rydén, P., Nylander, K."miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples". International Journal of Oncology 38, no. 1 (2011): 61-69. https://doi.org/10.3892/ijo_00000824
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