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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

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Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January 2011 Volume 38 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Instability and impending instability of the thoracolumbar spine in patients with spinal metastases: a systematic review

Michael H. Weber, Shane Burch, Jenny Buckley, Meic H. Schmidt, Michael G. Fehlings, Frank D. Vrionis, Charles G. Fisher
Pages: 5-12
Published online on: 01 January 2011

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Article Open Access

Utility of the novel bladder preservation therapy, BOAI-CDDP-radiation (OMC-regimen), for elderly patients with invasive bladder cancer

Haruhito Azuma, Teruo Inamoto, Naokazu Ibuki, Takanobu Ubai, Yatsugu Kotake, Kiyoshi Takahara, Satoshi Kiyama, Hayahito Nomi, Hiroshi Uehara, Kazumasa Komura, Kazuhiro Yamamoto, Yoshihumi Narumi, Yoji Katsuoka
Pages: 13-24
Published online on: 01 January 2011

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Article Open Access

Mutation in the RNA binding protein TIS11D/ZFP36L2 is associated with the pathogenesis of acute leukemia

Eisaku Iwanaga, Tomoko Nanri, Hiroaki Mitsuya, Norio Asou
Pages: 25-31
Published online on: 01 January 2011

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Article Open Access

Feasibility of tailored, selective and effective anticancer chemotherapy by direct injection of docetaxel-loaded immunoliposomes into Her2/neu positive gastric tumor xenografts

Yuji Yamamoto, Motohira Yoshida, Mitsunori Sato, Koichi Sato, Satoshi Kikuchi, Hiroki Sugishita, Jun Kuwabara, Yusuke Matsuno, You Kojima, Masamitsu Morimoto, Atsushi Horiuchi, Yuji Watanabe
Pages: 33-39
Published online on: 01 January 2011

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Article Open Access

Assessment of angiogenesis by CD105 and nestin expression in peritumor tissue of glioblastoma

Gigliola Sica, Gina Lama, Carmelo Anile, Maria Concetta Geloso, Giuseppe La Torre, Pasquale De Bonis, Giulio Maira, Libero Lauriola, Meena Jhanwar-Uniyal, Annunziato Mangiola
Pages: 41-49
Published online on: 01 January 2011

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Article Open Access

Tumor localization of an anti-TGF-β antibody and its effects on gliomas

Petra Hülper, Walter Schulz-Schaeffer, Christian Dullin, Peter Hoffmann, Jay Harper, Leslie Kurtzberg, Scott Lonning, Wilfried Kugler, Max Lakomek, Bernhard Erdlenbruch
Pages: 51-59
Published online on: 01 January 2011

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Article Open Access

miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples

M. Rentoft, J. Fahlén, P. J. Coates, G. Laurell, B. Sjöström, P. Rydén, K. Nylander
Pages: 61-69
Published online on: 01 January 2011

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Article

Adnectin CT-322 inhibits tumor growth and affects microvascular architecture and function in Colo205 tumor xenografts

Maximilian Ackermann, Irvith M. Carvajal, Brent A. Morse, Miguel Moreta, Steven O'Neil, Sylvie Kossodo, Jeffrey D. Peterson, Vera Delventhal, H. Nicholas Marsh, Eric S. Furfine, Moritz A. Konerding
Pages: 71-80
Published online on: 01 January 2011

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Article

Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo

Hidemi Toyoda, Eckard Wimmer, Jeronimo Cello
Pages: 81-87
Published online on: 01 January 2011

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Article

Overexpression of human ortholog of mammalian enabled (hMena) is associated with the expression of mutant p53 protein in human breast cancers

Akihiro Toyoda, Aya Yokota, Teruyoshi Saito, Hidetada Kawana, Morihiro Higashi, Yoshio Suzuki, Tomoaki Tanaka, Motoo Kitagawa, Kenichi Harigaya
Pages: 89-96
Published online on: 01 January 2011

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Article

CXCR4-transfected human umbilical cord blood-derived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomas

Soon A. Park, Chung Heon Ryu, Seong Muk Kim, Jung Yeon Lim, Sang In Park, Chang Hyun Jeong, Jin Ae Jun, Ji Hyeon Oh, Sun Hwa Park, Wonil Oh, Sin-Soo Jeun
Pages: 97-103
Published online on: 01 January 2011

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Article

Hsp90 inhibition increases p53 expression and destabilizes MYCN and MYC in neuroblastoma

Paul L. Regan, Joshua Jacobs, Gerald Wang, Jaime Torres, Robby Edo, Jennifer Friedmann, Xao X. Tang
Pages: 105-112
Published online on: 01 January 2011

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Article

Indoleamine 2,3-dioxygenase promotes peritoneal dissemination of ovarian cancer through inhibition of natural killercell function and angiogenesis promotion

Hiroaki Nonaka, Yasushi Saga, Hiroyuki Fujiwara, Hidetoshi Akimoto, Akiyo Yamada, Syota Kagawa, Yuji Takei, Shizuo Machida, Osamu Takikawa, Mitsuaki Suzuki
Pages: 113-120
Published online on: 01 January 2011

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Article

Down-regulation of CYLD as a trigger for NF-κB activation and a mechanism of apoptotic resistance in hepatocellular carcinoma cells

Toni Urbanik, Bruno Christian Köhler, Regina Johanna Boger, Marcus Alexander Wörns, Steffen Heeger, Gerd Otto, Nadine Hövelmeyer, Peter Robert Galle, Marcus Schuchmann, Ari Waisman, Henning Schulze-Bergkamen
Pages: 121-131
Published online on: 01 January 2011

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Article

Overexpression of fibroblast growth factor receptor 4 in high-grade pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

Norio Motoda, Yoko Matsuda, Munehiko Onda, Toshiyuki Ishiwata, Eiji Uchida, Zenya Naito
Pages: 133-143
Published online on: 01 January 2011

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Article

GLUT-1 staining of squamous cell carcinomas of the uterine cervix identifies a novel element of invasion

Arnulf Mayer, Michael Höckel, Lars-Christian Horn, Heinz Schmidberger, Peter Vaupel
Pages: 145-150
Published online on: 01 January 2011

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Article

Preponderance of cells with stem cell characteristics in metastasising mouse mammary tumours induced by deregulated EphB4 and ephrin-B2 expression

Philip Kaenel, Caroline Schwab, Kathrin Mülchi, Carlos Wotzkow, Anne-Catherine Andres
Pages: 151-160
Published online on: 01 January 2011

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Article

Genetic alterations after carbon ion irradiation in human lung adenocarcinoma cells

Emmanouil Fokas, An You, Janko Juricko, Rita Engenhart-Cabillic, Han-Xiang An
Pages: 161-168
Published online on: 01 January 2011

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Article

Leucine-rich protein 130 contributes to apoptosis resistance of human hepatocarcinoma cells

Mickaël Michaud, Stéphane Barakat, Sandrine Magnard, Dominique Rigal, Loris G. Baggetto
Pages: 169-178
Published online on: 01 January 2011

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Article

HARPΔ111-136 enhances radiation-induced apoptosis of U87MG glioblastoma by induction of the proapoptotic protein CHOP

Racha Karaky, Emilie Gobbo, Paule Opolon, Jean Delbé, José Courty, Franck Griscelli, Michel Perricaudet, Dominique Martel-Renoir
Pages: 179-188
Published online on: 01 January 2011

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Article

Mechanisms underlying resistance to cetuximab in the HNSCC cell line: Role of AKT inhibition in bypassing this resistance

Magali Rebucci, Paul Peixoto, Amélie Dewitte, Nicole Wattez, Marie-Adeline De Nuncques, Nicolas Rezvoy, Claire Vautravers-Dewas, Marie-Pierre Buisine, Eric Guerin, Jean-Philippe Peyrat, Eric Lartigau, Amélie Lansiaux
Pages: 189-200
Published online on: 01 January 2011

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Article

RUNX3 copy number predicts the development of UC-associated colorectal cancer

Toshiaki Watanabe, Takashi Kobunai, Hiroki Ikeuchi, Yoko Yamamoto, Keiji Matsuda, Soichiro Ishihara, Keijiro Nozawa, Hisae Iinuma, Takamitsu Kanazawa, Toshiaki Tanaka, Tadashi Yokoyama, Tsuyoshi Konishi, Kiyoshi Eshima, Yoichi Ajioka, Toshifumi HIbi, Mamoru Watanabe, Tetsuichiro Muto, Hirokazu Nagawa
Pages: 201-207
Published online on: 01 January 2011

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Article

Caveolin-1 mediates tumor cell migration and invasion and its regulation by miR-133a in head and neck squamous cell carcinoma

Nijiro Nohata, Toyoyuki Hanazawa, Naoko Kikkawa, Muradil Mutallip, Lisa Fujimura, Hirofumi Yoshino, Kazumori Kawakami, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
Pages: 209-217
Published online on: 01 January 2011

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Article Open Access

SKP2 confers resistance of pancreatic cancer cells towards TRAIL-induced apoptosis

Susanne Schüler, Sandra Diersch, Rainer Hamacher, Roland M. Schmid, Dieter Saur, Günter Schneider
Pages: 219-225
Published online on: 01 January 2011

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Article

Evaluation of the anticancer activities of two fungal polycyclic ethanones, alternethanoxins A and B, and two of their derivatives

Marina Bury, Biancavaleria Punzo, Alexander Berestetskiy, Benjamin Lallemand, Jacques Dubois, Florence Lefranc, Véronique Mathieu, Anna Andolfi, Robert Kiss, Antonio Evidente
Pages: 227-232
Published online on: 01 January 2011

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Article

Patient surveillance after treatment for soft-tissue sarcoma

Frank E. Johnson, Keita Sakata, Suchira Sarkar, Riccardo A. Audisio, William G. Kraybill, John F. Gibbs, Alan L. Beitler, Katherine S. Virgo
Pages: 233-239
Published online on: 01 January 2011

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Article

Placenta growth factor induces melanoma resistance to temozolomide through a mechanism that involves the activation of the transcription factor NF-κB

Lauretta Levati, Federica Ruffini, Alessia Muzi, Kazuo Umezawa, Grazia Graziani, Stefania D'Atri, Pedro Miguel Lacal
Pages: 241-247
Published online on: 01 January 2011

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Article

TRAIL-induced caspase/p38 activation is responsible for the increased catalytic and invasive activities of Akt

Bo K. Sun, Joo-Hang Kim, Hoan N. Nguyen, So Y. Kim, Seeun Oh, Yong J. Lee, Jae J. Song
Pages: 249-256
Published online on: 01 January 2011

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Article

Binding of the transcription factor Slug to the L1CAM promoter is essential for transforming growth factor-β1 (TGF-β)-induced L1CAM expression in human pancreatic ductal adenocarcinoma cells

Claudia Geismann, Alexander Arlt, Iris Bauer, Marco Pfeifer, Uwe Schirmer, Peter Altevogt, Susanne Sebens Müerköster, Heiner Schäfer
Pages: 257-266
Published online on: 01 January 2011

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Article

PI3 kinase integrates Akt and MAP kinase signaling pathways in the regulation of prostate cancer

Anna Goc, Belal Al-Husein, Samith T. Kochuparambil, Junxiu Liu, Warren W.D. Heston, Payaningal R. Somanath
Pages: 267-277
Published online on: 01 January 2011

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Article

Two small molecule compounds, LLL12 and FLLL32, exhibit potent inhibitory activity on STAT3 in human rhabdomyosarcoma cells

Chang-Ching Wei, Sarah Ball, Li Lin, Aiguo Liu, James R. Fuchs, Pui-Kai Li, Chenglong Li, Jiayuh Lin
Pages: 279-285
Published online on: 01 January 2011

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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