Cancer prevalence in the city of Naples: Contribution of the GP database analyses to the cancer registries network

Pizzi,Claudia; Arpino,Grazia; Acampora,Giuseppe; Aiello,Nadia; De Rosa,Augusto; Diaferia,Immacolata; Di Nunzio,Alessandro; Fragna,Giuseppe; Franco,Amedeo; Russo,Maria; Sansone,Fulvia; Scarpati,Carmela; Spinuso,Antonio; Arpino,Giovanni; Luce,Amalia; Tommasielli,Giuseppina; Caraglia,Michele; De Placido,Sabino

doi:10.3892/mco.2013.101

July-August 2013 Volume 1 Issue 4

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July-August 2013 Volume 1 Issue 4

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Article

Cancer prevalence in the city of Naples: Contribution of the GP database analyses to the cancer registries network

Authors:
- Claudia Pizzi
- Grazia Arpino
- Giuseppe Acampora
- Nadia Aiello
- Augusto De Rosa
- Immacolata Diaferia
- Alessandro Di Nunzio
- Giuseppe Fragna
- Amedeo Franco
- Maria Russo
- Fulvia Sansone
- Carmela Scarpati
- Antonio Spinuso
- Giovanni Arpino
- Amalia Luce
- Giuseppina Tommasielli
- Michele Caraglia
- Sabino De Placido
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Affiliations: Consorzio Nazionale delle Cooperative Mediche - Italian Society of General Medicine (SIMG), 80131 Naples, Italy, Department of Clinical Medicine and Surgery, Faculty of Medicine, ‘Federico II’ University, 80131 Naples, Italy, Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, 80138 Naples, Italy
Pages: 726-732
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Published online on: April 4, 2013

https://doi.org/10.3892/mco.2013.101
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Abstract

The Italian cancer registries network has not been sufficiently developed in the Southern regions. General practitioners (GPs) are knowledgeable about the prevalence, incidence and mortality for different types of cancer in their patient populations. The aim of this pilot study was to verify the feasibility and reliability of the characterization of cancer populations using GP databases in order to evaluate the impact of cancer in the general population of Naples. The characteristics of the cases studied have been collected by interview or electronic health record and recorded on paper or magnetic supports, appropriately conforming to the current privacy law. Databases are centralized, stored and codified on electronic data‑sheets and periodically elaborated by the ‘Consorzio Nazionale delle Cooperative Mediche’ and ‘Federico II’ University. The present study was initiated on September 15, 2004. The analysed geographical area included the suburbs of ‘Stella’ and ‘San Carlo all'Arena’, situated in the historical center of Naples and corresponding to Health Care District 29 of the local health service. The analysis included 16,927 men and women (age range, 6‑97 years) from the outpatient offices of 12 GPs who agreed to participate in the study. Results showed that the analysed population represents 16.3% of the general population residing in the area under study. We identified 342 (2%) patients with cancer, 143 (0.8%) of whom were men and 199 (1.2%) women (M/F ratio of 0.7). Of the 342 patients, 10 (5 men and 5 women) had a double cancer; thus, a total of 352 malignancies was characterized. Cancer prevalence was 2,020/100,000 inhabitants. This estimate is lower compared to the national prevalence (2,683/100,000 inhabitants) but higher compared to that in other southern Italian areas. Results, stratified by International Classification of Disease, ninth revision (ICD‑IX), based on factors including gender and age, demonstrated that breast cancer, urogenital tumours and colorectal cancer are the most frequently occurring types of cancer identified among the inhabitants of Naples. Cancer prevalence in the historical center of Naples is in concordance with national estimates and projections and National Cancer Registries may be easily and accurately supported by GP medical databases.

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1.	Greenlee RT, Murray T, Bolden S and Wingo PA: Cancer statistics, 2000. CA Cancer J Clin. 50:7–33. 2000. View Article : Google Scholar
2.	Jemal A, Siegel R, Xu J and Ward E: Cancer statistics, 2010. CA Cancer J Clin. 60:277–300. 2010. View Article : Google Scholar
3.	World Health Organization: Regional Office for Europe: Population health and waste management: scientific data and policy opinions. Report of a WHO workshop. Rome, Italy. 29–30–March. 2007
4.	Berrino F, Verdecchia A, Lutz JM, Lombardo C, Micheli A and Capocaccia R; EUROCARE Working Group: Comparative cancer survival information in Europe. Eur J Cancer. 45:901–908. 2009. View Article : Google Scholar : PubMed/NCBI
5.	Lillini R, Vercelli M, Quaglia A, Micheli A and Capocaccia R: Use of socio-economic factors and healthcare resources to estimate cancer survival in European countries with partial national cancer registration. Tumori. 97:265–274. 2011.
6.	Micheli A, Mugno E, Krogh V, et al EUROPREVAL Working Group: Cancer prevalence in European registry areas. Ann Oncol. 13:840–865. 2002. View Article : Google Scholar : PubMed/NCBI
7.	Mariotto A, Dally LG, Micheli A, Canario F and Verdecchia A: Cancer prevalence in Italian regions with local cancer registries. Tumori. 85:400–407. 1999.PubMed/NCBI
8.	Micheli A, Francisci S, Krogh V, Rossi AG and Crosignani P: Cancer prevalence in Italian cancer registry areas: the ITAPREVAL study. ITAPREVAL Working Group. Tumori. 85:309–369. 1999.PubMed/NCBI
9.	De Angelis R, Grande E, Inghelmann R, et al: Cancer prevalence estimates in Italy from 1970 to 2010. Tumori. 93:392–397. 2007.PubMed/NCBI
10.	AIRTUM Working Group: Italian cancer figures, report 2010: cancer prevalence in Italy. Patients living with cancer, long-term survivors and cured patients. Epidemiol Prev. 34:1–188. 2010.PubMed/NCBI
11.	Crocetti E and Buzzoni C; AIRTUM Working Group: Italy is one of the European countries with the greatest population observed by cancer registries. Epidemiol Prev. 34:822010.PubMed/NCBI
12.	AIRTUM Working Group; Crocetti E and Buzzoni C: New incidence and mortality data. 2003–2005. Epidemiol Prev. 33:e1–e3. e5–e26. 2009.(In Italian).
13.	Grande E, Inghelmann R, Francisci S, et al: Regional estimates of all cancer malignancies in Italy. Tumori. 93:345–351. 2007.PubMed/NCBI
14.	Fazzo L, Belli S, Minichilli F, et al Working Group: Cluster analysis of mortality and malformations in the provinces of Naples and Caserta (Campania Region). Ann Ist Super Sanita. 44:99–111. 2008.PubMed/NCBI
15.	Martuzzi M, Mitis F, Bianchi F, Minichilli F, Comba P and Fazzo L: Cancer mortality and congenital anomalies in a region of Italy with intense environmental pressure due to waste. Occup Environ Med. 66:725–732. 2009. View Article : Google Scholar : PubMed/NCBI
16.	Fazzo L, De Santis M, Mitis F, Benedetti M, Martuzzi M, Comba P and Fusco M: Ecological studies of cancer incidence in an area interested by dumping waste sites in Campania (Italy). Ann Ist Super Sanita. 47:181–191. 2011.PubMed/NCBI
17.	Altavista P, Belli S, Bianchi F, et al: Cause-specific mortality in an area of Campania with numerous waste disposal sites. Epidemiol Prev. 28:311–321. 2004.PubMed/NCBI
18.	Barba M, Mazza A, Guerriero C, et al: Wasting lives: the effects of toxic waste exposure on health. The case of Campania, Southern Italy. Cancer Biol Ther. 12:106–111. 2011. View Article : Google Scholar
19.	Guerriero C and Cairns J: The potential monetary benefits of reclaiming hazardous waste sites in the Campania region: an economic evaluation. Environ Health. 8:282009. View Article : Google Scholar : PubMed/NCBI
20.	Bidoli E, Franceschi S and Montella M: Cancer mortality by urbanization and proximity to the sea coast in Campania Region, southern Italy. Tumori. 84:460–466. 1998.PubMed/NCBI
21.	Picone GM, Pizzi C, Quartuccio A, Scognamiglio G, et al: Incidence and pathological characteristics of prostate cancer in Italy: a contribution to the screening debate. Cancer Detect Prev. 30:455–458. 2006. View Article : Google Scholar : PubMed/NCBI
22.	Riccardi F, Nappi O, Balzano A, et al: Neuroendocrine tumors diagnosed at the Antonio Cardarelli hospital (Naples, Italy) between 2006–2009: a single-institution analysis. Int J Immunopathol Pharmacol. 24:251–256. 2011.PubMed/NCBI
23.	Fusco M, Pezzi A, Benatti P, et al: Clinical features and colorectal cancer survival: an attempt to explain differences between two different Italian regions. Eur J Cancer. 46:142–149. 2010. View Article : Google Scholar : PubMed/NCBI
24.	Pizzi C, Acampora G, Aiello N, De Rosa A, et al: Cancer prevalence in Naples: analysis in a general practitioners network. Ann Oncol. 16(Suppl 7): H362005.

Journals

International Journal of Molecular Medicine

International Journal of Oncology

Molecular Medicine Reports

Oncology Reports

Experimental and Therapeutic Medicine

Oncology Letters

Biomedical Reports

Molecular and Clinical Oncology

World Academy of Sciences Journal

International Journal of Functional Nutrition

International Journal of Epigenetics

Medicine International

Cancer prevalence in the city of Naples: Contribution of the GP database analyses to the cancer registries network

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