|
1.
|
El-Serag HB, Marrero JA, Rudolph L and
Reddy KR: Diagnosis and treatment of hepatocellular carcinoma.
Gastroenterology. 134:1752–1763. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
2.
|
Trinchet JC, Alperovitch A, Bedossa P,
Degos F, Hainaut P and Beers BV: Epidemiology, prevention,
screening and diagnosis of hepatocellular carcinoma. Bull Cancer.
96:35–43. 2009.(In French).
|
|
3.
|
Debruyne EN and Delanghe JR: Diagnosing
and monitoring hepatocellular carcinoma with alpha-fetoprotein: new
aspects and applications. Clin Chim Acta. 395:19–26. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
4.
|
Singhal A, Jayaraman M, Dhanasekaran DN
and Kohli V: Molecular and serum markers in hepatocellular
carcinoma: predictive tools for prognosis and recurrence. Crit Rev
Oncol Hematol. 82:116–140. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
5.
|
Leerapun A, Suravarapu SV, Bida JP, et al:
The utility of Lens culinaris agglutinin-reactive alpha-fetoprotein
in the diagnosis of hepatocellular carcinoma: evaluation in a
United States referral population. Clin Gastroenterol Hepatol.
5:394–402. 2007. View Article : Google Scholar
|
|
6.
|
Kobayashi M, Hosaka T, Ikeda K, et al:
Highly sensitive AFP-L3% assay is useful for predicting recurrence
of hepatocellular carcinoma after curative treatment pre- and
postoperatively. Hepatology Res. 41:1036–1045. 2011.
|
|
7.
|
Joo M, Chi JG and Lee H: Expressions of
HSP70 and HSP27 in hepatocellular carcinoma. J Korean Med Sci.
20:829–834. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Luk JM, Lam CT, Siu AF, et al: Proteomic
profiling of hepatocellular carcinoma in Chinese cohort reveals
heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their
associated prognostic values. Proteomics. 6:1049–1057. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
9.
|
Shin E, Ryu HS, Kim SH, Jung H, Jang JJ
and Lee K: The clinicopathological significance of heat shock
protein 70 and glutamine synthetase expression in hepatocellular
carcinoma. J Hepatobiliary Pancreat Sci. 18:544–550. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
10.
|
Tremosini S, Forner A, Boix L, et al:
Prospective validation of an immunohistochemical panel (glypican 3,
heat shock protein 70 and glutamine synthetase) in liver biopsies
for diagnosis of very early hepatocellular carcinoma. Gut.
61:1481–1487. 2012. View Article : Google Scholar
|
|
11.
|
Diehl JA, Yang W, Rimerman RA, Xiao H and
Emili A: Hsc70 regulates accumulation of cyclin D1 and cyclin
D1-dependent protein kinase. Mol Cell Biol. 23:1764–1774. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
12.
|
Calderwood SK, Khaleque MA, Sawyer DB and
Ciocca DR: Heat shock proteins in cancer: chaperones of
tumorigenesis. Trends Biochem Sci. 31:164–172. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13.
|
Filmus J, Capurro M and Rast J: Glypicans.
Genome Biol. 9:2242008. View Article : Google Scholar
|
|
14.
|
Zittermann SI, Capurro MI, Shi W and
Filmus J: Soluble Glypican 3 inhibits the growth of hepatocellular
carcinoma in vitro and in vivo. Int J Cancer. 126:1291–1301.
2010.PubMed/NCBI
|
|
15.
|
Zittermann SI, Capurro MI, Shi W and
Filmus J: Glypican-3 promotes the growth of hepatocellular
carcinoma by stimulating canonical Wnt signaling. Cancer Res.
65:6245–6254. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
16.
|
Shirakawa H, Kumnuma T, Nishimura Y, et
al: Glypican-3 is a useful diagnostic marker for a component of
hepatocellular carcinoma in human liver cancer. Int J Oncol.
34:649–656. 2009.PubMed/NCBI
|
|
17.
|
Guido M, Roskams T, Pontisso P, et al:
Squamous cell carcinoma antigen in human liver carcinogenesis. J
Clin Pathol. 61:445–447. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18.
|
Trerotoli P, Fransvea E, Angelotti U, et
al: Tissue expression of squamous cellular carcinoma antigen (SCCA)
is inversely correlated to tumor size in HCC. Mol Cancer. 8:292009.
View Article : Google Scholar : PubMed/NCBI
|
|
19.
|
Giannelli G, Marinosci F, Sgarra C, Lupo
L, Dentico P and Antonaci S: Clinical role of tissue and serum
levels of SCCA antigen in hepatocellular carcinoma. Int J Cancer.
116:579–583. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
20.
|
Beneduce L, Castaldi F, Marino M, et al:
Squamous cell carcinoma antigen-immunoglobulin M complexes as novel
biomarkers for hepatocellular carcinoma. Cancer. 103:2558–2565.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
21.
|
Pontisso P, Quarta S, Caberlotto C, et al:
Progressive increase of SCCA-IgM immune complexes in cirrhotic
patients is associated with development of hepatocellular
carcinoma. Int J Cancer. 119:735–740. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
22.
|
Kladney RD, Bulla GA, Guo L, et al: GP73,
a novel Golgi-localized protein upregulated by viral infection.
Gene. 249:53–65. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
23.
|
Zhang F, Gu Y, Li X, Wang W, He J and Peng
T: Up-regulated Golgi phosphoprotein 2 (GOLPH2) expression in lung
adenocarcinoma tissue. Clin Biochem. 43:983–991. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
24.
|
Fritzsche FR, Kristiansen G, Riener MO,
Dietel M and Oelrich B: GOLPH2 expression may serve as diagnostic
marker in seminomas. BMC Urol. 10:42010. View Article : Google Scholar : PubMed/NCBI
|
|
25.
|
Fritzsche FR, Riener MO, Dietel M, Moch H,
Jung K and Kristiansen G: GOLPH2 expression in renal cell cancer.
BMC Urol. 8:152008. View Article : Google Scholar : PubMed/NCBI
|
|
26.
|
Kristiansen G, Fritzsche FR, Wassermann K,
et al: GOLPH2 protein expression as a novel tissue biomarker for
prostate cancer: implications for tissue-based diagnostics. Br J
Cancer. 99:939–948. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
27.
|
Shi Y, Chen J, Li L, et al: A study of
diagnostic value of golgi protein GP73 and its genetic assay in
primary hepatic carcinoma. Technol Cancer Res Treat. 10:287–294.
2011.PubMed/NCBI
|
|
28.
|
Tian L, Wang Y, Xu D, et al: Serological
AFP/Golgi protein 73 could be a new diagnostic parameter of hepatic
diseases. Int J Cancer. 129:1923–1931. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29.
|
Riener MO, Stenner F, Liewen H, et al:
Golgi phosphoprotein 2 (GOLPH2) expression in liver tumors and its
value as a serum marker in hepatocellular carcinomas. Hepatology.
49:1602–1609. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
30.
|
Zhou Y, Yin X, Ying J and Zhang B: Golgi
protein 73 versus alpha-fetoprotein as a biomarker for
hepatocellular carcinoma: a diagnostic meta-analysis. BMC Cancer.
12:172012. View Article : Google Scholar : PubMed/NCBI
|
|
31.
|
Mao YL, Yang HY, Xu HF, et al:
Significance of Golgi glyco-protein 73, a new tumor marker in
diagnosis of hepatocellular carcinoma: a primary study. Zhonghua Yi
Xue Za Zhi. 88:948–951. 2008.(In Chinese).
|
|
32.
|
Drake RR, Schwegler EE, Malik G, Diaz J,
Block T, Mehta A and Semmes OJ: Lectin capture strategies combined
with mass spectrometry for the discovery of serum glycoprotein
biomarkers. Mol Cell Proteomics. 5:1957–1967. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
33.
|
Zhang Y, Deng ZS, Liao MM, Wang N, Zhang
XQ, Yu HY and Zhang YD: Tumor associated glycoprotein-72 is a novel
marker for poor survival in hepatocellular carcinoma. Pathol Oncol
Res. 18:911–916. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34.
|
Milenic DE, Brady ED, Garmestani K, Albert
PS, Abdulla A and Brechbiel MW: Improved efficacy of
alpha-particle-targeted radiation therapy: dual targeting of human
epidermal growth factor receptor-2 and tumor-associated glycoprote
in 72. Cancer. 116:1059–1066. 2010. View Article : Google Scholar
|
|
35.
|
Mracek T, Stephens NA, Gao D, et al:
Enhanced ZAG production by subcutaneous adipose tissue is linked to
weight loss in gastrointestinal cancer patients. Br J Cancer.
104:441–447. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
36.
|
Wang F, Geng Y, Zhang WM and Geng X:
Identification of ZAG protein as a novel serologic biomarker
candidate for liver cancer. Adv Mater Res. 340:383–389. 2012.
View Article : Google Scholar
|
|
37.
|
Naraki T, Kohno N, Saito H, Fujimoto Y,
Ohhira M, Morita T and Kohgo Y: Gamma-carboxyglutamic acid content
of hepatocellular carcinoma-associated des-gamma-carboxy
prothrombin. Biochim Biophys Acta. 1586:287–298. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
38.
|
Nakamura S, Nouso K, Sakaguchi K, et al:
Sensitivity and specificity of des-gamma-carboxy prothrombin for
diagnosis of patients with hepatocellular carcinomas varies
according to tumor size. Am J Gastroenterol. 101:2038–2043. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
39.
|
Baek YH, Lee JH, Jang JS, et al:
Diagnostic role and correlation with staging systems of PIVKA-II
compared with AFP. Hepatogastroenterology. 56:763–767.
2009.PubMed/NCBI
|
|
40.
|
Yamamoto K, Imamura H, Matsuyama Y, et al:
Significance of alpha-fetopmtein and des-gamma-carbroxy prothrombin
in patients with hepatocellular carcinoma undergoing hepatectomy.
Ann Surg Oncol. 16:2795–2804. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
41.
|
Yamamoto K, Imamura H, Matsuyama Y, et al:
AFP, AFP-L3, DCP, and GP73 as markers for monitoring treatment
response and recurrence and as surrogate markers of
clinicopathological variables of HCC. J Gastroenterol.
45:1272–1282. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
42.
|
Yao DF, Dong ZZ and Yao M: Specific
molecular markers in hepatocellular carcinoma. Hepatobiliary
Pancreat Dis Int. 6:241–247. 2007.PubMed/NCBI
|
|
43.
|
Cui R, He J, Zhang F, et al: Diagnostic
value of protein induced by vitamin K absence (PIVKAII) and
hepatoma-specific band of serum gamma-glutamyl transferase (GGTII)
as hepatocellular carcinoma markers complementary to
alpha-fetoprotein. Br J Cancer. 88:1878–1882. 2003. View Article : Google Scholar
|
|
44.
|
Wang CS, Lin CL, Lee HC, et al: Usefulness
of serum des-gamma-carboxy prothrombin in detection of
hepatocellular carcinoma. World J Gastroenterol. 11:6115–6119.
2005.PubMed/NCBI
|
|
45.
|
Tangkijvanich P, Tosukhowong P, Bunyongyod
P, et al: Alpha-L-fucosidase as a serum marker of hepatocellular
carcinoma in Thailand. Southeast Asian J Trop Med Public Health.
30:110–114. 1999.PubMed/NCBI
|
|
46.
|
Fawzy Montaser M, Amin Sakr M and Omar
Khalifa M: Alpha-L-fucosidase as a tumour marker of hepatocellular
carcinoma. Arab J Gastroenterol. 13:9–13. 2012.PubMed/NCBI
|
|
47.
|
Pillai AA and Fimmel CJ: Emerging serum
biomarkers of HCC. Clin Gastroenterol. 27:247–262. 2012.
|
|
48.
|
Zhou L, Liu J and Luo F: Serum tumor
markers for detection of hepatocellular carcinoma. World J
Gastroenterol. 12:1175–1181. 2006.PubMed/NCBI
|
|
49.
|
Balzarini P, Benetti A, Invernici G, et
al: Transforming growth factor-beta1 induces microvascular
abnormalities through a down-modulation of neural cell adhesion
molecule in human hepatocellular carcinoma. Lab Invest.
92:1297–1309. 2012. View Article : Google Scholar
|
|
50.
|
Dong ZZ, Yao DF, Yao M, et al: Clinical
impact of plasma TGF-beta1 and circulating TGF-beta1 mRNA in
diagnosis of hepatocellular carcinoma. Hepatobiliary Pancreat Dis
Int. 7:288–295. 2008.PubMed/NCBI
|
|
51.
|
Xiang ZL, Zeng ZC, Fan J, et al: Gene
expression profiling of fixed tissues identified hypoxia-inducible
factor-1α, VEGF, and matrix metalloproteinase-2 as biomarkers of
lymph node metastasis in hepatocellular carcinoma. Clin Cancer Res.
17:5463–5472. 2011.PubMed/NCBI
|
|
52.
|
Zhang L, Wang JN, Tang JM, et al: VEGF is
essential for the growth and migration of human hepatocellular
carcinoma cells. Mol Biol Rep. 39:5085–5093. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
53.
|
Zhi H, Zhan J, Deng QL, et al:
Postoperative detection of AFP mRNA in the peripheral blood of
hepatic cellular carcinoma patients and its correlation with
recurrence. Zhonghua Zhong Liu Za Zhi. 29:112–115. 2007.(In
Chinese).
|
|
54.
|
Yamamoto Y, Kosaka N, Tanaka M, et al:
MicroRNA-500 as a potential diagnostic marker for hepatocellular
carcinoma. Biomarkers. 14:529–538. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
55.
|
Xiong Y, Fang JH, Yun JP, et al: Effects
of microRNA-29 on apoptosis, tumorigenicity, and prognosis of
hepatocellular carcinoma. Hepatology. 51:836–845. 2010.PubMed/NCBI
|
|
56.
|
Hou J, Lin L, Zhou W, et al:
Identification of miRNomes in human liver and hepatocellular
carcinoma reveals miR-199a/b-3p as therapeutic target for
hepatocellular carcinoma. Cancer Cell. 19:232–243. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
57.
|
Xu Y, Xia F, Ma L, Shan J, et al:
MicroRNA-122 sensitizes HCC cancer cells to adriamycin and
vincristine through modulating expression of MDR and inducing cell
cycle arrest. Cancer Lett. 310:160–169. 2011.PubMed/NCBI
|
|
58.
|
Volinia S, Calin GA, Liu CG, et al: A
microRNA expression signature of human solid tumors defines cancer
gene targets. Proc Natl Acad Sci USA. 103:2257–2261. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
59.
|
Medina PP, Nolde M and Slack FJ: OncomiR
addiction in an in vivo model of microRNA-21-induced pre-B-cell
lymphoma. Nature. 467:86–90. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
60.
|
Meng F, Henson R, Wehbe-Janek H, Ghoshal
K, Jacob ST and Patel T: MicroRNA-21 regulates expression of the
PTEN tumor suppressor gene in human hepatocellular cancer.
Gastroenterology. 133:647–58. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
61.
|
Tomimaru Y, Eguchi H, et al: Circulating
microRNA-21 as a novel biomarker for hepatocellular carcinoma. J
Hepatol. 56:167–175. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
62.
|
Jin ZH, Yang RJ, Dong B and Xing BC:
Progenitor gene DLK1 might be an independent prognostic factor of
liver cancer. Expert Opin Biol Ther. 8:371–377. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
63.
|
Liu Y, Li Y, Guo F, et al: Identification
of HTA as a novel-specific marker for human hepatocellular
carcinoma. J Cancer Res Clin Oncol. 136:1187–1192. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
64.
|
Xieraili M, Yasen M, Mogushi K, et al:
Villin 1 is a predictive factor for the recurrence of high serum
alpha-fetoprotein-associated hepatocellular carcinoma after
hepatectomy. Cancer Sci. 103:1493–1501. 2012. View Article : Google Scholar
|
